NO20081548L - Prosess for syntese av forbindelser for selektininhibitorer - Google Patents

Prosess for syntese av forbindelser for selektininhibitorer

Info

Publication number
NO20081548L
NO20081548L NO20081548A NO20081548A NO20081548L NO 20081548 L NO20081548 L NO 20081548L NO 20081548 A NO20081548 A NO 20081548A NO 20081548 A NO20081548 A NO 20081548A NO 20081548 L NO20081548 L NO 20081548L
Authority
NO
Norway
Prior art keywords
compounds
synthesis
selectin inhibitors
preparation
present application
Prior art date
Application number
NO20081548A
Other languages
English (en)
Inventor
Youchu Wang
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20081548L publication Critical patent/NO20081548L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Foreliggende søknad vedrører området anti-inflammatoriske substanser, og mer spesielt fremstilling av forbindelser som virker som antagonister til pattedyr-adhesjonsproteiner kjent som selektiner. I noen utførelsesformer tilveiebringer foreliggende søknad metoder for fremstilling av forbindelser for behandling av selektin-medierte lidelser som har formelen VI: VI hvor R1, R2, R3, p og q er definert her.
NO20081548A 2005-10-05 2008-03-31 Prosess for syntese av forbindelser for selektininhibitorer NO20081548L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72373405P 2005-10-05 2005-10-05
PCT/US2006/039000 WO2007044475A1 (en) 2005-10-05 2006-10-05 Process for the synthesis of compounds for selectin inhibition

Publications (1)

Publication Number Publication Date
NO20081548L true NO20081548L (no) 2008-04-28

Family

ID=37672216

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081548A NO20081548L (no) 2005-10-05 2008-03-31 Prosess for syntese av forbindelser for selektininhibitorer

Country Status (19)

Country Link
US (1) US20070082923A1 (no)
EP (1) EP1931638A1 (no)
JP (1) JP2009511488A (no)
KR (1) KR20080053389A (no)
CN (1) CN101277936A (no)
AR (1) AR058079A1 (no)
AU (1) AU2006302375A1 (no)
BR (1) BRPI0616906A2 (no)
CA (1) CA2624552A1 (no)
CR (1) CR9854A (no)
EC (1) ECSP088340A (no)
GT (1) GT200600447A (no)
IL (1) IL190435A0 (no)
NO (1) NO20081548L (no)
PE (1) PE20070590A1 (no)
RU (1) RU2008112191A (no)
TW (1) TW200738639A (no)
WO (1) WO2007044475A1 (no)
ZA (1) ZA200802990B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0809509A2 (pt) * 2007-03-30 2014-09-16 Wyeth Corp Composto, composição farmacêutica, métodos para inibir a adesão intracelular mediada pela selectina, e para tratar ou prevenir uma doença ou distúrbio em um mamífero, e, uso de um composto.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239280B1 (en) * 1999-06-30 2001-05-29 Merck & Co., Inc. Process for synthesizing biaryl inhibitors of farnesyl-protein transferase
WO2005047258A2 (en) * 2003-11-10 2005-05-26 Wyeth Methods and compositions for selectin inhibition

Also Published As

Publication number Publication date
CR9854A (es) 2008-05-21
EP1931638A1 (en) 2008-06-18
US20070082923A1 (en) 2007-04-12
IL190435A0 (en) 2008-11-03
AU2006302375A1 (en) 2007-04-19
BRPI0616906A2 (pt) 2011-07-05
CN101277936A (zh) 2008-10-01
KR20080053389A (ko) 2008-06-12
CA2624552A1 (en) 2007-04-19
PE20070590A1 (es) 2007-07-11
AR058079A1 (es) 2008-01-23
TW200738639A (en) 2007-10-16
ECSP088340A (es) 2008-06-30
WO2007044475A1 (en) 2007-04-19
JP2009511488A (ja) 2009-03-19
GT200600447A (es) 2007-05-08
RU2008112191A (ru) 2009-11-10
ZA200802990B (en) 2008-12-31

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application