NO20084056L - Oktahydro-pyrrol[3,4-B]pyrrolderivater og deres anvendelse som histamin-3-reseptorligander - Google Patents
Oktahydro-pyrrol[3,4-B]pyrrolderivater og deres anvendelse som histamin-3-reseptorliganderInfo
- Publication number
- NO20084056L NO20084056L NO20084056A NO20084056A NO20084056L NO 20084056 L NO20084056 L NO 20084056L NO 20084056 A NO20084056 A NO 20084056A NO 20084056 A NO20084056 A NO 20084056A NO 20084056 L NO20084056 L NO 20084056L
- Authority
- NO
- Norway
- Prior art keywords
- pyrrole
- octahydro
- histamine
- receptor ligands
- derivatives
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 150000003233 pyrroles Chemical class 0.000 title 1
- YETODIXQMRZKEG-UHFFFAOYSA-N 1,2,3,3a,4,5,6,6a-octahydropyrrolo[2,3-c]pyrrole Chemical class C1NCC2NCCC21 YETODIXQMRZKEG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Addiction (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77650906P | 2006-02-24 | 2006-02-24 | |
| PCT/US2007/062329 WO2007100990A2 (en) | 2006-02-24 | 2007-02-16 | Octahydro-pyrrolo[3,4-b] pyrrole derivatives and their use as histamine-3 receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20084056L true NO20084056L (no) | 2008-10-27 |
Family
ID=38325247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20084056A NO20084056L (no) | 2006-02-24 | 2008-09-24 | Oktahydro-pyrrol[3,4-B]pyrrolderivater og deres anvendelse som histamin-3-reseptorligander |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7728031B2 (es) |
| EP (1) | EP2001885A2 (es) |
| JP (1) | JP5463038B2 (es) |
| KR (2) | KR20140097612A (es) |
| CN (2) | CN101415709A (es) |
| AU (1) | AU2007220889B2 (es) |
| BR (1) | BRPI0708258A2 (es) |
| CA (1) | CA2641624A1 (es) |
| CR (2) | CR10287A (es) |
| EC (1) | ECSP088687A (es) |
| GT (1) | GT200800166A (es) |
| IL (1) | IL193270A0 (es) |
| MX (1) | MX2008010805A (es) |
| MY (2) | MY149513A (es) |
| NO (1) | NO20084056L (es) |
| NZ (2) | NZ595275A (es) |
| RU (1) | RU2492172C2 (es) |
| SG (2) | SG170033A1 (es) |
| TW (1) | TWI389910B (es) |
| UA (1) | UA97639C2 (es) |
| WO (1) | WO2007100990A2 (es) |
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| MX2007014114A (es) | 2005-05-10 | 2008-03-14 | Intermune Inc | Derivados de piridona para modular el sistema de proteina cinasa activada por estres. |
| US7728031B2 (en) | 2006-02-24 | 2010-06-01 | Abbott Laboratories | Octahydro-pyrrolo[3,4-b]pyrrole derivatives |
| PE20090362A1 (es) | 2007-06-08 | 2009-04-04 | Janssen Pharmaceutica Nv | Derivados de piperidina/piperazina como moduladores de dgat |
| AU2008258560C1 (en) | 2007-06-08 | 2014-04-10 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| WO2008148840A1 (en) | 2007-06-08 | 2008-12-11 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| RU2486187C2 (ru) * | 2007-09-11 | 2013-06-27 | Эбботт Лэборетриз | N-ОКСИДЫ ОКТАГИДРО-ПИРРОЛО[3,4-b]ПИРРОЛА |
| CN101918409A (zh) * | 2007-11-21 | 2010-12-15 | 雅培制药有限公司 | 联芳基取代的二氮杂双环烷衍生物 |
| US8383657B2 (en) | 2007-12-21 | 2013-02-26 | Abbott Laboratories | Thiazolylidine urea and amide derivatives and methods of use thereof |
| JP5627574B2 (ja) | 2008-06-03 | 2014-11-19 | インターミューン, インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| PE20140572A1 (es) | 2008-06-05 | 2014-05-16 | Janssen Pharmaceutica Nv | Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar |
| WO2010135470A1 (en) * | 2009-05-19 | 2010-11-25 | Intermune, Inc. | Pifenidone derivatives for treating bronchial asthma |
| US8252801B1 (en) | 2009-06-03 | 2012-08-28 | Abbott Laboratories | Treatment of schizophrenia and related disorders |
| WO2011068926A1 (en) * | 2009-12-04 | 2011-06-09 | Tetralogic Pharmaceuticals Corp. | Iap inhibitors |
| US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| US10233195B2 (en) | 2014-04-02 | 2019-03-19 | Intermune, Inc. | Anti-fibrotic pyridinones |
| GB201416351D0 (en) * | 2014-09-16 | 2014-10-29 | Shire Internat Gmbh | Heterocyclic derivatives |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CS229067B1 (en) * | 1981-08-20 | 1984-04-16 | Svorad Stolc | Medicinal preparation with antiarhythmic and supporting effect applied with hypoxia,and method of preparing active substance thereof |
| DE3906365A1 (de) | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| ES2079391T3 (es) * | 1989-04-17 | 1996-01-16 | Bayer Ag | Procedimiento para la obtencion de 2,7-diazabiciclo(3.3.0)octanos. |
| AU702752B2 (en) | 1995-05-11 | 1999-03-04 | Pharmacia & Upjohn Company | Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones |
| PT874849E (pt) * | 1995-12-21 | 2002-01-30 | Pfizer | Derivados octa-hidro-pirrolo¬1,2-a|pirazina 2,7-substituidos |
| KR100666838B1 (ko) | 1998-10-27 | 2007-01-11 | 아보트 러보러터리즈 | 프로스타글란딘 엔도퍼옥사이드 h 신타제 생합성 억제제 및 이를 포함하는 약제학적 조성물 |
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| AU2003276930A1 (en) | 2003-03-24 | 2004-11-23 | Novascreen Biosciences Corporation | Drug discovery method and apparatus |
| DE602004018637D1 (de) | 2003-04-09 | 2009-02-05 | Biogen Idec Inc | A2a-adenosinrezeptorantagonisten |
| US7399765B2 (en) * | 2003-09-19 | 2008-07-15 | Abbott Laboratories | Substituted diazabicycloalkane derivatives |
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| EP1687271A1 (en) | 2003-11-25 | 2006-08-09 | Texcontor Etablissement | A method for the preparation of (2s, 3ar, 7as)-octahydro-1h-indole-2-carboxylic acid as key intermediate in the preparation of trandolapril by reacting a cyclohexyl aziridine with a dialkyl malonate |
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