NO20085257L - Purinonderivater som HM74a-agonister - Google Patents

Purinonderivater som HM74a-agonister

Info

Publication number: NO20085257L
Authority: NO; Norway
Prior art keywords: purinone derivatives; hm74a agonists; agonists; purinone; derivatives
Prior art date: 2006-06-23

Application number

NO20085257A

Other languages

English (en)

Norwegian (no)

Inventor

Brian Metcalf

Anlai Wang

Chu-Biao Xue

Changsheng Zheng

Ganfeng Cao

Michael Xia

Hai Fen Ye

Original Assignee

Incyte Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-23

Filing date

2008-12-16

Publication date

2009-01-19

2008-12-16 Application filed by Incyte Corp filed Critical Incyte Corp

2009-01-19 Publication of NO20085257L publication Critical patent/NO20085257L/no

Links

239000000556 agonist Substances 0.000 title abstract 2
UFZNZKGKBWOSJG-UHFFFAOYSA-N purin-2-one Chemical class O=C1N=CC2=NC=NC2=N1 UFZNZKGKBWOSJG-UHFFFAOYSA-N 0.000 title abstract 2
101001035752 Homo sapiens Hydroxycarboxylic acid receptor 3 Proteins 0.000 abstract 1
102100039356 Hydroxycarboxylic acid receptor 3 Human genes 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO20085257A 2006-06-23 2008-12-16 Purinonderivater som HM74a-agonister NO20085257L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US81595506P	2006-06-23	2006-06-23
US92281807P	2007-04-11	2007-04-11
PCT/US2007/071891 WO2007150025A2 (en)	2006-06-23	2007-06-22	Purinone derivatives as hm74a agonists

Publications (1)

Publication Number	Publication Date
NO20085257L true NO20085257L (no)	2009-01-19

Family

ID=38721463

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20085257A NO20085257L (no)	2006-06-23	2008-12-16	Purinonderivater som HM74a-agonister

Country Status (14)

Country	Link
US (4)	US7511050B2 (de)
EP (1)	EP2044074A2 (de)
JP (1)	JP5584466B2 (de)
KR (1)	KR20090025261A (de)
CN (1)	CN101466714B (de)
AR (1)	AR061625A1 (de)
AU (1)	AU2007260851B2 (de)
BR (1)	BRPI0713619A2 (de)
CA (1)	CA2656039A1 (de)
IL (1)	IL195904A0 (de)
MX (1)	MX2009000170A (de)
NO (1)	NO20085257L (de)
TW (1)	TWI423977B (de)
WO (1)	WO2007150025A2 (de)

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SE0302756D0 (sv) *	2003-10-17	2003-10-17	Astrazeneca Ab	Novel Compounds
MX2009000170A (es)	2006-06-23	2009-01-23	Incyte Corp	Derivados de purinona como agonistas de hm74a.
MX2009000169A (es) *	2006-06-23	2009-01-26	Incyte Corp	Derivados de purinona como agonistas de hm74a.
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
KR101799429B1 (ko) *	2010-05-03	2017-11-21	에스케이바이오팜 주식회사	신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물
EP2582709B1 (de)	2010-06-18	2018-01-24	Sanofi	Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP3490579B1 (de)	2016-07-27	2025-09-10	Hartis-Pharma SA	Kombinationstherapie zur behandlung von sichelzellanämie und wiederherstellung von rbc-funktionen
AR112457A1 (es) *	2017-08-02	2019-10-30	Lilly Co Eli	Derivados de [1,2,4]triazolo[4,3-a]pirazin-6(5h)-ona
PE20200932A1 (es)	2017-10-27	2020-09-17	Bayer Pharma AG	Novedosos derivados de pirazolo-pirrolo-pirimidina como inhibidores de p2x3
TWI877770B (zh)	2018-02-27	2025-03-21	美商英塞特公司	作為a2a / a2b抑制劑之咪唑并嘧啶及三唑并嘧啶
US11220510B2 (en)	2018-04-09	2022-01-11	Incyte Corporation	Pyrrole tricyclic compounds as A2A / A2B inhibitors
EP3810610A1 (de)	2018-05-18	2021-04-28	Incyte Corporation	Kondensierte pyrimidinderivate als a2a/a2b-inhibitoren
WO2020010197A1 (en)	2018-07-05	2020-01-09	Incyte Corporation	Fused pyrazine derivatives as a2a / a2b inhibitors
TWI829857B (zh)	2019-01-29	2024-01-21	美商英塞特公司	作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶

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CA1095906A (en) *	1977-02-14	1981-02-17	Davis L. Temple, Jr.	Heterocyclopyrimidines, compositions and therapeutic process
BE863525A (fr)	1977-02-14	1978-07-31	Bristol Myers Co	Heterocyclopyrimidines
US4404380A (en) *	1977-02-14	1983-09-13	Mead Johnson & Company	Triazolopyrimidines
WO1990001031A1 (en) *	1988-07-21	1990-02-08	The Upjohn Company	Pyrazolo-pyrrolo-pyrimidine-diones
DK0417790T3 (da) *	1989-09-14	1997-04-07	Kyowa Hakko Kogyo Kk	S-triazolo(3,4-i)purin-derivater
JPH083168A (ja) *	1994-06-15	1996-01-09	Yamasa Shoyu Co Ltd	４−メチル−９Ｈ−イミダゾ［１，２−ａ］プリン−９−オン類
JP3204879B2 (ja)	1995-08-04	2001-09-04	オリエンタル酵母工業株式会社	パン用酵母の包装紙
WO1998003411A1 (fr)	1996-07-18	1998-01-29	Montania	Bouchon avec recipient auxiliaire et procede de realisation
DE19629378A1 (de)	1996-07-20	1998-01-29	Boehringer Ingelheim Kg	Neue Triazolopurine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO1998056820A1 (en)	1997-06-12	1998-12-17	Smithkline Beecham Corporation	Hm74a receptor
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EP1377834A2 (de)	2001-04-11	2004-01-07	Glaxo Group Limited	Medikamente die modulatoren von hm74 und/oder hm74a activität sind
UA80258C2 (en)	2001-09-06	2007-09-10	Biogen Inc	Methods of treating pulmonary disease
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EP1597587A2 (de) *	2003-02-17	2005-11-23	Bayer HealthCare AG	Diagnose und therapie von erkrankungen, die mit dem g-protein gekoppelten rezeptor hm74a (hm74a) assoziiert sind
PL1781657T3 (pl) *	2004-02-14	2013-08-30	Glaxosmithkline Ip Dev Ltd	Leki o aktywności wobec receptora HM74A
WO2005089188A2 (en)	2004-03-12	2005-09-29	General Motors Corporation	Variable resistance strut assemblies and articles containing the same
US7267695B2 (en)	2004-06-25	2007-09-11	American Prosthetic Components, Inc.	Four hole offset alignment device
WO2006021892A2 (en)	2004-08-27	2006-03-02	Endocube S.A.S.	Hm74 and hm74a in cuboidal endothelial cells as associated with inflammation
KR20070070231A (ko) *	2004-10-22	2007-07-03	스미스클라인 비참 코포레이션	Ｈｍ７４ａ 수용체 활성을 가지는 크산틴 유도체
WO2006045564A1 (en) *	2004-10-22	2006-05-04	Smithkline Beecham Corporation	Xanthine derivatives with hm74a receptor activity
GB0516462D0 (en)	2005-08-10	2005-09-14	Smithkline Beecham Corp	Novel compounds
ES2401128T3 (es)	2005-08-10	2013-04-17	Glaxosmithkline Llc	Derivados de xantina como agonistas selectivos de HM74A
MX2009000170A (es) *	2006-06-23	2009-01-23	Incyte Corp	Derivados de purinona como agonistas de hm74a.
MX2009000169A (es)	2006-06-23	2009-01-26	Incyte Corp	Derivados de purinona como agonistas de hm74a.

2007
- 2007-06-22 MX MX2009000170A patent/MX2009000170A/es active IP Right Grant
- 2007-06-22 US US11/766,981 patent/US7511050B2/en active Active
- 2007-06-22 EP EP07798937A patent/EP2044074A2/de not_active Withdrawn
- 2007-06-22 BR BRPI0713619-6A patent/BRPI0713619A2/pt not_active IP Right Cessation
- 2007-06-22 CA CA002656039A patent/CA2656039A1/en not_active Abandoned
- 2007-06-22 AU AU2007260851A patent/AU2007260851B2/en not_active Ceased
- 2007-06-22 TW TW096122480A patent/TWI423977B/zh not_active IP Right Cessation
- 2007-06-22 JP JP2009516748A patent/JP5584466B2/ja not_active Expired - Fee Related
- 2007-06-22 WO PCT/US2007/071891 patent/WO2007150025A2/en not_active Ceased
- 2007-06-22 AR ARP070102782A patent/AR061625A1/es not_active Application Discontinuation
- 2007-06-22 KR KR1020087031335A patent/KR20090025261A/ko not_active Abandoned
- 2007-06-22 CN CN2007800221892A patent/CN101466714B/zh not_active Expired - Fee Related
2008
- 2008-11-03 US US12/263,990 patent/US8039478B2/en not_active Expired - Fee Related
- 2008-12-11 IL IL195904A patent/IL195904A0/en unknown
- 2008-12-16 NO NO20085257A patent/NO20085257L/no not_active Application Discontinuation
2011
- 2011-10-17 US US13/275,214 patent/US8703783B2/en active Active
2014
- 2014-04-18 US US14/256,350 patent/US20140371216A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2007260851B2 (en)	2013-01-17
CN101466714A (zh)	2009-06-24
WO2007150025A3 (en)	2008-02-07
US8039478B2 (en)	2011-10-18
US8703783B2 (en)	2014-04-22
US20140371216A1 (en)	2014-12-18
MX2009000170A (es)	2009-01-23
AR061625A1 (es)	2008-09-10
IL195904A0 (en)	2009-09-01
EP2044074A2 (de)	2009-04-08
CA2656039A1 (en)	2007-12-27
AU2007260851A1 (en)	2007-12-27
KR20090025261A (ko)	2009-03-10
TW200813064A (en)	2008-03-16
JP5584466B2 (ja)	2014-09-03
US7511050B2 (en)	2009-03-31
US20080045554A1 (en)	2008-02-21
TWI423977B (zh)	2014-01-21
BRPI0713619A2 (pt)	2013-01-15
US20090286774A1 (en)	2009-11-19
CN101466714B (zh)	2013-02-06
WO2007150025A2 (en)	2007-12-27
US20120035172A1 (en)	2012-02-09
JP2009541355A (ja)	2009-11-26

Legal Events

Date	Code	Title	Description
2016-01-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20085257L (no)	2009-01-19	Purinonderivater som HM74a-agonister
NO20085099L (no)	2009-02-16	Puritonderivativer som HM74A agonister
MY148429A (en)	2013-04-30	Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with benzyl groups, method for producing drugs containing said compounds and use thereof
NO20075298L (no)	2007-12-20	Novel thiophene derivatives as sphingosine-1-phosphate-1 receptor agonists
NO20083726L (no)	2008-11-25	Spiroindolinon derivater
NO20083462L (no)	2008-10-09	Nye tiofenderivater som S1P1/EDG1-reseptoragonister
NO20083669L (no)	2008-10-27	4-aryl-2amino-pyrimidiner eller 4-aryl-2-aminoalkylpyrimidiner som jak-2-modulatorer og fremgangsmater for anvendelse derav
WO2008094992A3 (en)	2008-12-04	2-aminopyridine derivatives useful as kinase inhibitors
EA201100503A1 (ru)	2011-10-31	Глюкозидные производные и их применения
EA200870193A1 (ru)	2009-02-27	Цитотоксические агенты, включающие новые производные томаймицина, и их терапевтическое применение
NO20082793L (no)	2008-06-20	Nye tiofenderivater
NO20080675L (no)	2008-03-13	P38-Map kinaseinhibitorer og metoder for deres anvendelse
TNSN08326A1 (en)	2009-12-29	Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
WO2007133802A3 (en)	2008-01-24	Pharmaceutical formulations of pimavanserin
MA32467B1 (fr)	2011-07-03	Derives de piperidinyle agonistes de gpcr
TW200728307A (en)	2007-08-01	Novel spirochromanone derivatives
NO20093146L (no)	2009-10-15	Amino-pyridinderivater som S1P1/EDG1-reseptoragonister
UA102251C2 (ru)	2013-06-25	Производные аминодигидротиазина как ингибиторы васе для лечения болезни альцгеймера
NO20083918L (no)	2008-11-12	Dihydridiazepiner anvendelige som inhibitorer av proteinkinaser
NO20082124L (no)	2008-06-20	Bifenyloksyeddiksyrederivater for behandling av respiratorisk sykdom
NO20083708L (no)	2008-09-23	4-Fenyl-tiazol-5-karboksylsyre og 4-fenyl-tiazol-5-karboksylmider som PLK1-inhibitorer
EA201001747A1 (ru)	2011-08-30	Бензоксазиноновые производные, действующие в качестве агониста бета-2-адренорецептора, для лечения респираторных расстройств
EA201100612A1 (ru)	2011-12-30	Новые производные 2-амидотиадиазола
MY149854A (en)	2013-10-31	Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
UY32055A (es)	2010-03-26	Derivados sustituidos de la 5-Halo-N2-[sustituido](1-metil-1H-imidazol-4-il)pirimidin-2,-diamina y sus sales farmacéuticamente aceptables, procesos de preparación, composiciones y aplicaciones.