NO20092248L - Ny forbindelse med affinitet for amyloid - Google Patents

Ny forbindelse med affinitet for amyloid

Info

Publication number
NO20092248L
NO20092248L NO20092248A NO20092248A NO20092248L NO 20092248 L NO20092248 L NO 20092248L NO 20092248 A NO20092248 A NO 20092248A NO 20092248 A NO20092248 A NO 20092248A NO 20092248 L NO20092248 L NO 20092248L
Authority
NO
Norway
Prior art keywords
group
carbon
compound
amyloid
alzheimer
Prior art date
Application number
NO20092248A
Other languages
English (en)
Norwegian (no)
Inventor
Shigeyuki Tanifuji
Daisaku Nakamura
Shinya Takasaki
Yuki Okumura
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of NO20092248L publication Critical patent/NO20092248L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20092248A 2006-11-30 2009-06-10 Ny forbindelse med affinitet for amyloid NO20092248L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006324701 2006-11-30
PCT/JP2007/065955 WO2008065785A1 (en) 2006-11-30 2007-08-16 Novel compound having affinity for amyloid

Publications (1)

Publication Number Publication Date
NO20092248L true NO20092248L (no) 2009-08-05

Family

ID=39467583

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092248A NO20092248L (no) 2006-11-30 2009-06-10 Ny forbindelse med affinitet for amyloid

Country Status (14)

Country Link
US (1) US8207189B2 (de)
EP (1) EP2098522B1 (de)
JP (1) JP5180838B2 (de)
KR (1) KR20090083414A (de)
CN (1) CN101595108A (de)
AT (1) ATE529425T1 (de)
AU (1) AU2007326707A1 (de)
CA (1) CA2670436A1 (de)
ES (1) ES2371682T3 (de)
IL (1) IL198995A (de)
NO (1) NO20092248L (de)
NZ (1) NZ577511A (de)
TW (1) TW200823211A (de)
WO (1) WO2008065785A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
KR20100091965A (ko) * 2007-10-24 2010-08-19 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
AU2008314871A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
KR20100101577A (ko) * 2007-10-30 2010-09-17 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법
WO2009057576A1 (ja) * 2007-10-30 2009-05-07 Nihon Medi-Physics Co., Ltd. 新規アミロイド親和性化合物の使用及び製造方法
EP2218464A1 (de) * 2009-02-11 2010-08-18 Technische Universität München Verbindungen zur nichtinvasiven Messung von Aggregaten von Amyloidpeptiden
US20120263646A1 (en) 2009-10-15 2012-10-18 Guerbet Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases
CA2839199C (en) * 2011-06-24 2018-11-06 Nihon Medi-Physics Co., Ltd. Novel compound with amyloid affinity
CN107105667B (zh) * 2014-08-29 2021-08-17 Chdi基金会股份有限公司 用于成像亨廷顿蛋白的探针
CN121248676B (zh) * 2025-12-04 2026-03-06 重庆华邦制药有限公司 咪唑并[1,2-a]吡啶化合物及其制备方法与应用

Family Cites Families (26)

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US4727145A (en) * 1986-09-22 1988-02-23 Ortho Pharmaceutical Corporation 2- Or 3- aryl substituted imidazo [1,2-a]pyridines
US4791117A (en) 1986-09-22 1988-12-13 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines and their use as calcium channel blockers
US4871745A (en) 1986-09-22 1989-10-03 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo(1,2-A)pyridines and their use as antisecretory agents
DE4327027A1 (de) 1993-02-15 1994-08-18 Bayer Ag Imidazoazine
BR9611047A (pt) 1995-10-17 2000-03-08 Searle & Co Processo de deteção de ciclo oxigenase-2
US6812327B1 (en) 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
WO1999055304A1 (en) 1998-04-29 1999-11-04 Novartis Ag Methods and compositions for stabilizing acetylcholine compositions
AU759945B2 (en) 1998-08-20 2003-05-01 Regents Of The University Of California, The Methods for labeling beta-amyloid plaques and neurofibrillary tangles
JP4025468B2 (ja) 1999-07-29 2007-12-19 三井化学株式会社 有機電界発光素子
WO2001074813A2 (en) * 2000-03-31 2001-10-11 Ortho Mcneil Pharmaceutical, Inc. METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS
AU2001249679A1 (en) 2000-03-31 2001-10-15 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituted imidazopyridines
RU2324686C2 (ru) 2000-08-24 2008-05-20 Юнивесити Оф Питсбэг ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
CZ20032597A3 (cs) 2001-02-26 2004-12-15 Bristol-Myers Squibb Pharma Company Analogy kyseliny askorbové pro metaloradiofarmaceutika
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
CA2444214A1 (en) 2001-04-23 2002-10-31 The Trustees Of The University Of Pennsylvania Amyloid plaque aggregation inhibitors and diagnostic imaging agents
ATE337316T1 (de) 2001-06-21 2006-09-15 Smithkline Beecham Corp Imidazo 1,2-aöpyridin-derivate zur prophylaxe und behandlung von herpes-infektionen
CN1299777C (zh) 2001-08-27 2007-02-14 宾夕法尼亚州大学理事会 茋衍生物及其用于结合和成像淀粉样蛋白斑的用途
EP1547996A4 (de) 2002-08-30 2006-08-02 Bf Res Inst Inc Diagnostische sonden und heilmittel für krankheiten, bei denen prionprotein akkumuliert wird, und anfürbereagenzien für prionprotein
JP2006505610A (ja) 2002-11-05 2006-02-16 イヨン ベアム アプリカスィヨン エッス．アー． １８−ｆ標識放射性製剤の安定化
BRPI0418328A (pt) 2003-12-31 2007-05-02 Schering Plough Ltd controle de parasitas em animais pelo uso de derivados de imidazo [1,2-b]piridazina
TW200803903A (en) 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
US8303935B2 (en) * 2006-05-19 2012-11-06 Nihon Medi-Physics Co., Ltd. Alkoxy substituted imidazo[1,2-a]pyridines having affinity for amyloid
WO2007148755A1 (ja) 2006-06-21 2007-12-27 Nihon Medi-Physics Co., Ltd. 新規アミロイド親和性化合物
KR20100091965A (ko) * 2007-10-24 2010-08-19 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
AU2008314871A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
KR20100101577A (ko) * 2007-10-30 2010-09-17 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법

Also Published As

Publication number Publication date
AU2007326707A1 (en) 2008-06-05
CA2670436A1 (en) 2008-06-05
IL198995A (en) 2012-10-31
US8207189B2 (en) 2012-06-26
US20100069640A1 (en) 2010-03-18
WO2008065785A1 (en) 2008-06-05
CN101595108A (zh) 2009-12-02
IL198995A0 (en) 2010-02-17
EP2098522A1 (de) 2009-09-09
NZ577511A (en) 2012-04-27
JPWO2008065785A1 (ja) 2010-03-04
ES2371682T3 (es) 2012-01-09
KR20090083414A (ko) 2009-08-03
JP5180838B2 (ja) 2013-04-10
TW200823211A (en) 2008-06-01
EP2098522B1 (de) 2011-10-19
ATE529425T1 (de) 2011-11-15
EP2098522A4 (de) 2010-05-05

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