NO20092376L - Sfingosin-1-fosfat-reseptoragonist og -antagonistforbindelser - Google Patents

Sfingosin-1-fosfat-reseptoragonist og -antagonistforbindelser

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Publication number
NO20092376L
NO20092376L NO20092376A NO20092376A NO20092376L NO 20092376 L NO20092376 L NO 20092376L NO 20092376 A NO20092376 A NO 20092376A NO 20092376 A NO20092376 A NO 20092376A NO 20092376 L NO20092376 L NO 20092376L
Authority
NO
Norway
Prior art keywords
sphingosine
receptor agonist
antagonist compounds
phosphate receptor
receptor family
Prior art date
Application number
NO20092376A
Other languages
English (en)
Inventor
Thomas D Gordon
Kevin P Cusack
Grier A Wallace
Eric C Breinlinger
Shannon R Fix-Stenzel
Adrian D Hobson
Martin E Hayes
Graham K Ansell
Pintipa Grongsaard
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39562856&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20092376(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO20092376L publication Critical patent/NO20092376L/no

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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
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Abstract

Den foreliggende oppfinnelsen er rettet mot nye, kraftige og selektive midler, som er agonister eller antagonister av en eller flere av de individuelle reseptorer av S1P reseptor-familien. Forbindelsene ifølge oppfinnelsen er nyttige som terapeutika for å behandle medisinske tilstander assosiert med agonisme eller antagonisme av de individuelle reseptorene av S1P reseptor-familien.
NO20092376A 2006-12-21 2009-06-22 Sfingosin-1-fosfat-reseptoragonist og -antagonistforbindelser NO20092376L (no)

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PCT/US2007/026263 WO2008079382A1 (en) 2006-12-21 2007-12-21 Sphingosine-1 -phosphate receptor agonist and antagonist compounds

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DOP2009000149A (es) 2010-05-15
ECSP099435A (es) 2009-07-31
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AR064650A1 (es) 2009-04-15
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