NO20092547L - Antibakterielle kinolin-derivater - Google Patents

Antibakterielle kinolin-derivater

Info

Publication number
NO20092547L
NO20092547L NO20092547A NO20092547A NO20092547L NO 20092547 L NO20092547 L NO 20092547L NO 20092547 A NO20092547 A NO 20092547A NO 20092547 A NO20092547 A NO 20092547A NO 20092547 L NO20092547 L NO 20092547L
Authority
NO
Norway
Prior art keywords
quinoline derivatives
pharmaceutically acceptable
treatment
bacterial infection
compounds
Prior art date
Application number
NO20092547A
Other languages
English (en)
Other versions
NO342774B1 (no
Inventor
Jerome Emile Georges Guillemont
Koenraad Jozef Lodewij Andries
Anil Koul
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20092547L publication Critical patent/NO20092547L/no
Publication of NO342774B1 publication Critical patent/NO342774B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Den foreliggende oppfinnelsen angår nye substituerte kinolinderivater ifølge den generelle formel (Ia) eller formel (Ib): inkludert enhver stereokjemisk isomerform derav, et N-oksid derav, et farmasøytisk akseptabelt salt derav eller et solvat derav. De krevde forbindelsene er nyttige i behandlingen av en bakteriell infeksjon. Også krevet er en sammensetning omfattende en farmasøytisk akseptabel bærer og, som aktiv ingrediens, en terapeutisk effektiv mengde av de krevde forbindelsene, anvendelsen av de krevde forbindelsene eller sammensetninger for fremstillingen av et medikament for behandlingen av en bakteriell infeksjon og en fremgangsmåte for å fremstille de krevde forbindelsene.
NO20092547A 2006-12-06 2009-07-06 Antibakterielle kinolin-derivater NO342774B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125529 2006-12-06
PCT/EP2007/063316 WO2008068270A1 (en) 2006-12-06 2007-12-04 Antibacterial quinoline derivatives

Publications (2)

Publication Number Publication Date
NO20092547L true NO20092547L (no) 2009-08-24
NO342774B1 NO342774B1 (no) 2018-08-06

Family

ID=38124123

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092547A NO342774B1 (no) 2006-12-06 2009-07-06 Antibakterielle kinolin-derivater

Country Status (28)

Country Link
US (1) US20110166179A1 (no)
EP (1) EP2099759B1 (no)
JP (1) JP5356246B2 (no)
KR (1) KR101526175B1 (no)
CN (1) CN101553471B (no)
AR (1) AR064152A1 (no)
AT (1) ATE509915T1 (no)
AU (1) AU2007328890B2 (no)
BR (1) BRPI0720133A2 (no)
CA (1) CA2669829C (no)
CL (1) CL2007003517A1 (no)
CY (1) CY1112230T1 (no)
DK (1) DK2099759T3 (no)
ES (1) ES2366062T3 (no)
HR (1) HRP20110540T1 (no)
IL (1) IL199084A0 (no)
JO (1) JO2725B1 (no)
ME (1) ME01245B (no)
MX (1) MX2009005981A (no)
NO (1) NO342774B1 (no)
NZ (1) NZ577069A (no)
PL (1) PL2099759T3 (no)
PT (1) PT2099759E (no)
RS (1) RS51848B (no)
RU (1) RU2439058C2 (no)
SI (1) SI2099759T1 (no)
TW (1) TWI487525B (no)
WO (1) WO2008068270A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU24144B1 (es) * 2010-01-04 2016-01-29 Nippon Soda Co Compuesto heterocíclico conteniendo nitrógeno y fungicida para el uso en agricultura y jardinería
AR086411A1 (es) 2011-05-20 2013-12-11 Nippon Soda Co Compuesto heterociclico conteniendo nitrogeno y fungicida para el uso en agricultura y jardineria
RU2486175C2 (ru) * 2011-09-12 2013-06-27 Закрытое Акционерное Общество "Фарм-Синтез" Производные хинолина, в частности 5,6,7-замещенные 1-(2-хлорхинолин-3-ил)-4-диметиламино-2-(нафталин-1-ил)-1-фенилбутан-2-олы, способ получения и применение соединений
AU2013254670B2 (en) * 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
ES2576491T3 (es) * 2012-04-27 2016-07-07 Janssen Pharmaceutica, N.V. Derivados de quinolina antibacterianos
CN105232540A (zh) * 2015-09-29 2016-01-13 王洪燕 一种治疗烧伤后感染的药物组合物
US20250214980A1 (en) 2022-03-14 2025-07-03 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1042295B1 (en) * 1997-12-22 2005-09-07 Pharmacia & Upjohn Company LLC 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents
SI1527050T1 (sl) * 2002-07-25 2010-08-31 Janssen Pharmaceutica Nv Kinolinski derivati in njihova uporaba kot mikobakterijski inhibitorji
US7902225B2 (en) * 2004-01-23 2011-03-08 Janssen Pharmaceutica Nv Mycobacterial inhibitors
MXPA06013888A (es) * 2004-05-28 2007-01-26 Janssen Pharmaceutica Nv Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a los farmacos.
EE05394B1 (et) * 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis

Also Published As

Publication number Publication date
CY1112230T1 (el) 2015-12-09
ATE509915T1 (de) 2011-06-15
PT2099759E (pt) 2011-07-27
EP2099759B1 (en) 2011-05-18
KR101526175B1 (ko) 2015-06-05
AR064152A1 (es) 2009-03-18
TWI487525B (zh) 2015-06-11
BRPI0720133A2 (pt) 2014-02-04
EP2099759A1 (en) 2009-09-16
MX2009005981A (es) 2009-06-16
HRP20110540T1 (hr) 2011-08-31
DK2099759T3 (da) 2011-08-15
JP2010511671A (ja) 2010-04-15
CA2669829A1 (en) 2008-06-12
PL2099759T3 (pl) 2011-09-30
KR20090086611A (ko) 2009-08-13
ES2366062T3 (es) 2011-10-14
SI2099759T1 (sl) 2011-09-30
AU2007328890B2 (en) 2013-03-14
NO342774B1 (no) 2018-08-06
WO2008068270A1 (en) 2008-06-12
RU2009125520A (ru) 2011-01-20
RU2439058C2 (ru) 2012-01-10
CL2007003517A1 (es) 2008-07-11
TW200845986A (en) 2008-12-01
RS51848B (sr) 2012-02-29
US20110166179A1 (en) 2011-07-07
HK1137431A1 (en) 2010-07-30
CN101553471B (zh) 2013-04-03
CN101553471A (zh) 2009-10-07
ME01245B (me) 2013-06-20
JP5356246B2 (ja) 2013-12-04
JO2725B1 (en) 2013-09-15
AU2007328890A1 (en) 2008-06-12
CA2669829C (en) 2016-08-30
IL199084A0 (en) 2010-03-28
NZ577069A (en) 2011-09-30

Similar Documents

Publication Publication Date Title
NO20092542L (no) Antibakterielle kinolin-derivater
NO20092539L (no) Antibakterielle kinolin-derivater
MX2007010072A (es) Derivados de piperidina antibacterianos.
ATE455786T1 (de) 6-11 bicyclische ketolidderivate
NO20061657L (no) Pyrolderivater med antibakteriell aktivitet
JO2725B1 (en) Quinoline antibacterial derivatives
MX355050B (es) Derivados de quinolina antibacterianos.
NO20092540L (no) Antibakterielle kinolin-derivater
NO20092536L (no) Antibakterielle kinolin-derivater
NO20092541L (no) Antibakterielle kinolin-derivater
EA201491971A1 (ru) Антибактериальные хинолиновые производные