NO20100192L - Stabile salter av S-adenosylmetionin og fremgangsmater for fremstilling derav - Google Patents

Stabile salter av S-adenosylmetionin og fremgangsmater for fremstilling derav

Info

Publication number
NO20100192L
NO20100192L NO20100192A NO20100192A NO20100192L NO 20100192 L NO20100192 L NO 20100192L NO 20100192 A NO20100192 A NO 20100192A NO 20100192 A NO20100192 A NO 20100192A NO 20100192 L NO20100192 L NO 20100192L
Authority
NO
Norway
Prior art keywords
adenosylmethionine
processes
preparation
stable salts
same
Prior art date
Application number
NO20100192A
Other languages
English (en)
Other versions
NO343103B1 (no
Inventor
Ermanno Valoti
Daniele Giovannone
Marco Berna
Original Assignee
Gnosis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20100192(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gnosis Spa filed Critical Gnosis Spa
Publication of NO20100192L publication Critical patent/NO20100192L/no
Publication of NO343103B1 publication Critical patent/NO343103B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Den foreliggende oppfinnelse angår nye salter av Sadenosylmetionin (SAMe) med forbedret stabilitet og som inneholder i det minste 70 vekt% SAMe.
NO20100192A 2007-07-10 2010-02-08 Stabile salter av S-adenosylmetionin og fremgangsmåter for fremstilling derav NO343103B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001374A ITMI20071374A1 (it) 2007-07-10 2007-07-10 Sali stabili di s-adenosilmetionina e processo per il loro ottenimento.
PCT/IT2007/000736 WO2009008019A1 (en) 2007-07-10 2007-10-22 Stable salts of s-adenosylmethionine and process for the preparation thereof

Publications (2)

Publication Number Publication Date
NO20100192L true NO20100192L (no) 2010-02-08
NO343103B1 NO343103B1 (no) 2018-11-05

Family

ID=39639465

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20100192A NO343103B1 (no) 2007-07-10 2010-02-08 Stabile salter av S-adenosylmetionin og fremgangsmåter for fremstilling derav

Country Status (19)

Country Link
US (1) US8258115B2 (no)
EP (1) EP2170920B1 (no)
JP (2) JP2010533165A (no)
KR (1) KR101455208B1 (no)
CN (1) CN101730704B (no)
AU (1) AU2007356297B2 (no)
BR (1) BRPI0721887B8 (no)
CA (1) CA2707344C (no)
CY (1) CY1116266T1 (no)
DK (1) DK2170920T3 (no)
ES (1) ES2536402T3 (no)
IT (1) ITMI20071374A1 (no)
NO (1) NO343103B1 (no)
NZ (1) NZ582149A (no)
PL (1) PL2170920T3 (no)
PT (1) PT2170920E (no)
RS (1) RS54021B1 (no)
SI (1) SI2170920T1 (no)
WO (1) WO2009008019A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102186066B1 (ko) * 2013-01-16 2020-12-04 허버트 샘-이 엘엘씨 S-아데노실-l-메티오닌의 안정한 인돌-3-프로피오네이트염
WO2015028927A1 (en) * 2013-08-25 2015-03-05 Mahesh Kandula Compositions and methods for the treatment of metabolic diseases
WO2016185413A1 (en) 2015-05-20 2016-11-24 Nestec S.A. Modified release formulations
CN106349311B (zh) * 2016-08-23 2018-04-13 北京金阳利康医药有限公司 从酵母发酵液中提取s‑腺苷蛋氨酸的方法
IT201700074957A1 (it) * 2017-07-04 2019-01-04 Gnosis Spa Sale di (ss)-adenosil metionina con inositolo esafosfato e procedimento per ottenerlo
IT202000030914A1 (it) 2020-12-15 2022-06-15 Mario Antonio Basile Composizione farmaceutica solida di ademetionina e cannabidiolo e procedimento per ottenerla

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3330729A (en) * 1963-10-04 1967-07-11 Goodrich Co B F Sustained release tablet containing medicament admixed in a waterinsoluble acrylic acid cross-linked polymer and selected basic magnesium or calcium diluent
JPS4845950A (no) * 1971-10-13 1973-06-30
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
CA1187388A (en) 1978-09-20 1985-05-21 American Monitor Corporation Stabilization of working reagent solutions containing nadh, nadph, and/or enzymes, and the use of such stabilized reagents in enzymes or substrate assays
JPS5817392B2 (ja) * 1978-11-10 1983-04-06 大阪瓦斯株式会社 微粒子状凍結物製造装置
GB2064523B (en) * 1979-12-04 1983-06-29 Kanegafuchi Chemical Ind Stable composition of s-adenosyl-l-methionine
JPS5699797A (en) * 1980-01-10 1981-08-11 Kanegafuchi Chem Ind Co Ltd S-adenosyl-l-methionine-containing composition and its preparation
IT1137892B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
IT1139974B (it) * 1981-09-11 1986-09-24 Bioresearch Srl Derivati della s-adenosilmetionina,processo per la preparazione e composizioni terapeutiche che li contengono come principio attivo
JPS5849397A (ja) * 1981-09-18 1983-03-23 Kanegafuchi Chem Ind Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物およびその製造法
JPS60181095A (ja) 1984-02-27 1985-09-14 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物及びその製造法
US4704365A (en) * 1986-02-24 1987-11-03 Abbott Laboratories Composition and method for stabilization of dinucleotides
JPS6327424A (ja) 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
EP0421581A1 (en) 1989-10-03 1991-04-10 Warner-Lambert Company Chewable spray dried spheroidal microcapsules and wax coated microcapsules and methods for preparing same
US6451341B1 (en) * 1990-02-05 2002-09-17 Thomas J. Slaga Time release formulation of vitamins, minerals and other beneficial supplements
FR2695804B1 (fr) 1992-09-18 1994-11-25 Rhone Poulenc Nutrition Animal Compositions nutritives ou médicamenteuses pour l'administration aux ruminants à base de chitosane.
US5332727A (en) 1993-04-29 1994-07-26 Birkmayer U.S.A. Stable, ingestable and absorbable NADH and NADPH therapeutic compositions
GB2341798B (en) 1998-09-25 2001-03-14 Brian Whittle Associates Ltd Nutritional and pharmaceutical compositions comprising desiccants
MXPA02003230A (es) * 1999-09-30 2004-04-21 Saitec Srl Metodo y sistema para enfriar y efectuar un cambio de estado en una mezcla liquida.
IT1318535B1 (it) * 2000-05-25 2003-08-27 Chementecno Srl Processo per la preparazione di sali farmaceuticamente accettabili di(ss,rs)-s-adenosil-l-metionina.
US20020132780A1 (en) * 2001-01-12 2002-09-19 Heisey Matthew Thomas Low carbohydrate compositions, kits thereof, and methods of use
US20030069202A1 (en) 2000-06-02 2003-04-10 Kern Kenneth Norman Compositions, kits, and methods for promoting defined health benefits
US6759395B2 (en) * 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
WO2002102823A1 (en) 2001-06-14 2002-12-27 Orchid Chemicals & Pharmaceuticals Limited Stable salts of s-adenosyl-l-methionine (same) and the process for their preparation
US7799765B2 (en) * 2001-08-10 2010-09-21 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Association compound of trehalose or maltitol with metal ion compound
ITMI20012462A1 (it) 2001-11-22 2003-05-22 Gnosis Srl Processo per la preparazione di compresse comprendenti s-adenosilmetionina
US20050090512A1 (en) * 2003-10-28 2005-04-28 Kurt-Reiner Geiss Method of treating extreme physical or mental stress using L-theanine to obtain accelerated regeneration
ITRM20050344A1 (it) 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.

Also Published As

Publication number Publication date
BRPI0721887B1 (pt) 2019-06-25
ITMI20071374A1 (it) 2009-01-11
BRPI0721887A2 (pt) 2014-03-25
DK2170920T3 (en) 2015-05-11
AU2007356297B2 (en) 2012-05-24
US8258115B2 (en) 2012-09-04
CN101730704B (zh) 2013-08-14
AU2007356297A1 (en) 2009-01-15
EP2170920B1 (en) 2015-03-11
EP2170920A1 (en) 2010-04-07
JP2010533165A (ja) 2010-10-21
CY1116266T1 (el) 2017-02-08
KR20100032893A (ko) 2010-03-26
NZ582149A (en) 2012-02-24
BRPI0721887B8 (pt) 2021-05-25
RS54021B1 (sr) 2015-10-30
JP2015028043A (ja) 2015-02-12
US20100184715A1 (en) 2010-07-22
SI2170920T1 (sl) 2015-06-30
NO343103B1 (no) 2018-11-05
CA2707344A1 (en) 2009-01-15
PT2170920E (pt) 2015-07-06
CA2707344C (en) 2014-12-16
ES2536402T3 (es) 2015-05-25
CN101730704A (zh) 2010-06-09
KR101455208B1 (ko) 2014-10-28
PL2170920T3 (pl) 2015-07-31
WO2009008019A1 (en) 2009-01-15

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Legal Events

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Representative=s name: OSLO PATENTKONTOR AS, HOFFSVEIEN 1A, 0275 OSLO