NO300954B1 - Fremgangsmåte for fremstilling av et fosfolipid-innesluttet kationisk, lipofilt medikamentpreparat - Google Patents

Fremgangsmåte for fremstilling av et fosfolipid-innesluttet kationisk, lipofilt medikamentpreparat Download PDF

Info

Publication number: NO300954B1
Authority: NO; Norway
Prior art keywords: acid; cationic; drug; liposome; stated
Prior art date: 1987-11-18

Application number

NO902184A

Other languages

English (en)

Norwegian (no)

Other versions

NO902184L (no

NO902184D0 (no

Inventor

Eric Anton Forssen

Original Assignee

Nexstar Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-18

Filing date

1990-05-16

Publication date

1997-08-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22402210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO300954(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-05-16 Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc

1990-05-16 Publication of NO902184D0 publication Critical patent/NO902184D0/no

1990-07-13 Publication of NO902184L publication Critical patent/NO902184L/no

1997-08-25 Publication of NO300954B1 publication Critical patent/NO300954B1/no

Links

239000003814 drug Substances 0.000 title claims abstract description 57
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238000000034 method Methods 0.000 title claims abstract description 50
125000002091 cationic group Chemical group 0.000 title claims abstract description 20
238000002360 preparation method Methods 0.000 title claims description 10
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239000002253 acid Substances 0.000 claims abstract description 37
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO902184A 1987-11-18 1990-05-16 Fremgangsmåte for fremstilling av et fosfolipid-innesluttet kationisk, lipofilt medikamentpreparat NO300954B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12235487A	1987-11-18	1987-11-18
PCT/US1988/003995 WO1989004656A1 (en)	1987-11-18	1988-11-18	Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes

Publications (3)

Publication Number	Publication Date
NO902184D0 NO902184D0 (no)	1990-05-16
NO902184L NO902184L (no)	1990-07-13
NO300954B1 true NO300954B1 (no)	1997-08-25

Family

ID=22402210

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO902184A NO300954B1 (no)	1987-11-18	1990-05-16	Fremgangsmåte for fremstilling av et fosfolipid-innesluttet kationisk, lipofilt medikamentpreparat

Country Status (12)

Country	Link
EP (1)	EP0394314B2 (da)
JP (1)	JP2870657B2 (da)
KR (1)	KR960013282B1 (da)
AT (1)	ATE86104T1 (da)
AU (1)	AU609926B2 (da)
CA (1)	CA1331860C (da)
DE (1)	DE3878922T2 (da)
DK (1)	DK175736B1 (da)
HK (1)	HK120093A (da)
IE (1)	IE63518B1 (da)
NO (1)	NO300954B1 (da)
WO (1)	WO1989004656A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5227170A (en) *	1989-06-22	1993-07-13	Vestar, Inc.	Encapsulation process
IS1685B (is) *	1990-12-11	1998-02-24	Bracco International B.V.	Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
AU652247B2 (en) *	1992-02-11	1994-08-18	Nexstar Pharmaceuticals, Inc.	Inhibition of aggregation of drug containing particles
DE19639811A1 (de) *	1996-09-27	1998-04-02	Artur Herzog Dr Mesmer	Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
EP2198854B1 (en)	1997-09-18	2011-11-30	Pacira Pharmaceuticals, Inc.	Sustained-release liposomal anesthetic compositions
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1988
- 1988-11-17 IE IE344188A patent/IE63518B1/en not_active IP Right Cessation
- 1988-11-18 DE DE3878922T patent/DE3878922T2/de not_active Expired - Lifetime
- 1988-11-18 CA CA000583476A patent/CA1331860C/en not_active Expired - Lifetime
- 1988-11-18 JP JP1500971A patent/JP2870657B2/ja not_active Expired - Lifetime
- 1988-11-18 KR KR1019890701340A patent/KR960013282B1/ko not_active Expired - Lifetime
- 1988-11-18 WO PCT/US1988/003995 patent/WO1989004656A1/en not_active Ceased
- 1988-11-18 AU AU28162/89A patent/AU609926B2/en not_active Expired
- 1988-11-18 EP EP89900483A patent/EP0394314B2/en not_active Expired - Lifetime
- 1988-11-18 AT AT89900483T patent/ATE86104T1/de not_active IP Right Cessation
1990
- 1990-05-16 NO NO902184A patent/NO300954B1/no unknown
- 1990-05-17 DK DK199001221A patent/DK175736B1/da not_active IP Right Cessation
1993
- 1993-11-04 HK HK1200/93A patent/HK120093A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO902184L (no)	1990-07-13
AU609926B2 (en)	1991-05-09
HK120093A (en)	1993-11-12
DK122190A (da)	1990-07-17
JP2870657B2 (ja)	1999-03-17
CA1331860C (en)	1994-09-06
KR890701092A (ko)	1989-12-19
EP0394314B1 (en)	1993-03-03
NO902184D0 (no)	1990-05-16
IE63518B1 (en)	1995-05-03
DK122190D0 (da)	1990-05-17
EP0394314A4 (en)	1991-01-09
JPH03501019A (ja)	1991-03-07
DK175736B1 (da)	2005-02-07
DE3878922D1 (de)	1993-04-08
DE3878922T2 (de)	1996-04-11
EP0394314B2 (en)	1995-12-06
KR960013282B1 (ko)	1996-10-02
EP0394314A1 (en)	1990-10-31
IE883441L (en)	1989-05-18
ATE86104T1 (de)	1993-03-15
WO1989004656A1 (en)	1989-06-01
AU2816289A (en)	1989-06-14

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EP0219922B2 (en)	2002-08-28	Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
NO300954B1 (no)	1997-08-25	Fremgangsmåte for fremstilling av et fosfolipid-innesluttet kationisk, lipofilt medikamentpreparat
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CA1272686A (en)	1990-08-14	Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles and methods for using same for tumor therapy
AU2003207462A1 (en)	2003-07-30	Efficient liposomal encapsulation under mild conditions
WO2003057189A1 (en)	2003-07-17	Efficient liposomal encapsulation under mild conditions
CA2467060A1 (en)	2003-05-22	Lipid carrier compositions and methods for improved drug retention