NO310060B1 - Materiale for ben-erstatning og fremstilling derav - Google Patents

Materiale for ben-erstatning og fremstilling derav Download PDF

Info

Publication number: NO310060B1
Authority: NO; Norway
Prior art keywords: titanium; apatite; bone; surface layer; alkali
Prior art date: 1993-11-09

Application number

NO951567A

Other languages

English (en)

Norwegian (no)

Other versions

NO951567D0 (no

NO951567L (no

Inventor

Tadashi Kokubo

Original Assignee

Found Promotion Ind Science

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-09

Filing date

1995-04-25

Publication date

2001-05-14

1995-04-25 Application filed by Found Promotion Ind Science filed Critical Found Promotion Ind Science

1995-04-25 Publication of NO951567D0 publication Critical patent/NO951567D0/no

1995-05-18 Publication of NO951567L publication Critical patent/NO951567L/no

2001-05-14 Publication of NO310060B1 publication Critical patent/NO310060B1/no

Links

239000000463 material Substances 0.000 title claims abstract description 38
210000000988 bone and bone Anatomy 0.000 title claims description 27
238000004519 manufacturing process Methods 0.000 title claims description 10
RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims abstract description 52
239000010936 titanium Substances 0.000 claims abstract description 50
229910052719 titanium Inorganic materials 0.000 claims abstract description 46
229910052586 apatite Chemical group 0.000 claims abstract description 40
VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical group [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims abstract description 39
239000003513 alkali Substances 0.000 claims abstract description 25
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims abstract description 15
238000010438 heat treatment Methods 0.000 claims abstract description 15
238000000034 method Methods 0.000 claims abstract description 15
OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims abstract description 13
239000000316 bone substitute Substances 0.000 claims abstract description 8
230000007704 transition Effects 0.000 claims abstract description 8
229910045601 alloy Inorganic materials 0.000 claims abstract description 5
239000000956 alloy Substances 0.000 claims abstract description 5
239000000758 substrate Substances 0.000 claims description 27
239000002184 metal Substances 0.000 claims description 20
239000010410 layer Substances 0.000 claims description 17
239000002344 surface layer Substances 0.000 claims description 17
238000007654 immersion Methods 0.000 claims description 16
229910052751 metal Inorganic materials 0.000 claims description 15
229910001069 Ti alloy Inorganic materials 0.000 claims description 11
239000000243 solution Substances 0.000 claims description 11
239000011575 calcium Substances 0.000 claims description 9
150000002500 ions Chemical class 0.000 claims description 9
239000007864 aqueous solution Substances 0.000 claims description 7
239000011574 phosphorus Substances 0.000 claims description 6
229910052698 phosphorus Inorganic materials 0.000 claims description 6
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 5
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 5
229910052791 calcium Inorganic materials 0.000 claims description 5
229910001092 metal group alloy Inorganic materials 0.000 claims description 5
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 3
229910001424 calcium ion Inorganic materials 0.000 claims description 3
229910001415 sodium ion Inorganic materials 0.000 claims description 3
230000007423 decrease Effects 0.000 claims description 2
229910001414 potassium ion Inorganic materials 0.000 claims description 2
239000002585 base Substances 0.000 abstract description 3
239000011248 coating agent Substances 0.000 abstract description 3
238000000576 coating method Methods 0.000 abstract description 3
239000007943 implant Substances 0.000 description 18
239000012890 simulated body fluid Substances 0.000 description 13
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
238000002513 implantation Methods 0.000 description 10
230000015572 biosynthetic process Effects 0.000 description 8
241000283973 Oryctolagus cuniculus Species 0.000 description 7
239000010839 body fluid Substances 0.000 description 6
210000001124 body fluid Anatomy 0.000 description 6
210000002303 tibia Anatomy 0.000 description 5
230000000975 bioactive effect Effects 0.000 description 4
238000006243 chemical reaction Methods 0.000 description 4
-1 hydrogen ions Chemical class 0.000 description 4
229910052588 hydroxylapatite Inorganic materials 0.000 description 4
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 4
210000002381 plasma Anatomy 0.000 description 4
238000002233 thin-film X-ray diffraction Methods 0.000 description 4
238000001727 in vivo Methods 0.000 description 3
239000007769 metal material Substances 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
239000000853 adhesive Substances 0.000 description 2
230000001070 adhesive effect Effects 0.000 description 2
239000012670 alkaline solution Substances 0.000 description 2
238000004458 analytical method Methods 0.000 description 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
230000003247 decreasing effect Effects 0.000 description 2
238000009792 diffusion process Methods 0.000 description 2
239000012153 distilled water Substances 0.000 description 2
210000004394 hip joint Anatomy 0.000 description 2
239000000203 mixture Substances 0.000 description 2
230000006911 nucleation Effects 0.000 description 2
238000010899 nucleation Methods 0.000 description 2
229910052760 oxygen Inorganic materials 0.000 description 2
239000001301 oxygen Substances 0.000 description 2
239000011734 sodium Substances 0.000 description 2
239000000126 substance Substances 0.000 description 2
LLZRNZOLAXHGLL-UHFFFAOYSA-J titanic acid Chemical compound O[Ti](O)(O)O LLZRNZOLAXHGLL-UHFFFAOYSA-J 0.000 description 2
238000011282 treatment Methods 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
238000002441 X-ray diffraction Methods 0.000 description 1
239000002253 acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000004913 activation Effects 0.000 description 1
239000012237 artificial material Substances 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
230000001054 cortical effect Effects 0.000 description 1
239000013078 crystal Substances 0.000 description 1
229910003460 diamond Inorganic materials 0.000 description 1
239000010432 diamond Substances 0.000 description 1
238000002149 energy-dispersive X-ray emission spectroscopy Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
239000002241 glass-ceramic Substances 0.000 description 1
230000036571 hydration Effects 0.000 description 1
238000006703 hydration reaction Methods 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
229910001410 inorganic ion Inorganic materials 0.000 description 1
230000010354 integration Effects 0.000 description 1
150000002739 metals Chemical class 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000007586 pull-out test Methods 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
238000000550 scanning electron microscopy energy dispersive X-ray spectroscopy Methods 0.000 description 1
230000002269 spontaneous effect Effects 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
238000004154 testing of material Methods 0.000 description 1
239000010409 thin film Substances 0.000 description 1
210000004746 tooth root Anatomy 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/06—Titanium or titanium alloys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Medicinal Chemistry (AREA)
Orthopedic Medicine & Surgery (AREA)
Cardiology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Materials For Medical Uses (AREA)
Prostheses (AREA)

NO951567A 1993-11-09 1995-04-25 Materiale for ben-erstatning og fremstilling derav NO310060B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP30465993		1993-11-09
PCT/JP1994/001885 WO1995013100A1 (en)	1993-11-09	1994-11-07	Bone substitute material and process for producing the same

Publications (3)

Publication Number	Publication Date
NO951567D0 NO951567D0 (no)	1995-04-25
NO951567L NO951567L (no)	1995-05-18
NO310060B1 true NO310060B1 (no)	2001-05-14

Family

ID=17935689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO951567A NO310060B1 (no)	1993-11-09	1995-04-25	Materiale for ben-erstatning og fremstilling derav

Country Status (14)

Country	Link
US (1)	US5609633A (de)
EP (1)	EP0678300B1 (de)
KR (2)	KR0149134B1 (de)
CN (1)	CN1101705C (de)
AT (1)	ATE191856T1 (de)
AU (1)	AU671567B2 (de)
CA (1)	CA2150036C (de)
DE (1)	DE69424035T2 (de)
DK (1)	DK0678300T3 (de)
ES (1)	ES2147831T3 (de)
FI (1)	FI115445B (de)
NO (1)	NO310060B1 (de)
PT (1)	PT678300E (de)
WO (1)	WO1995013100A1 (de)

Families Citing this family (46)

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SE513556C2 (sv) *	1997-11-11	2000-10-02	Nobel Biocare Ab	Implantatelement med tunt ytskickt applicerat genom het isostatisk pressning
WO1999030632A1 (en) *	1997-12-18	1999-06-24	Comfort Biomedical, Inc.	Bone augmentation for prosthetic implants and the like
US6214049B1 (en)	1999-01-14	2001-04-10	Comfort Biomedical, Inc.	Method and apparatus for augmentating osteointegration of prosthetic implant devices
ATE235928T1 (de)	1998-09-15	2003-04-15	Isotis Nv	Beschichtungsverfahren von medizinischen implantaten
JP3325529B2 (ja)	1999-01-05	2002-09-17	有限会社相和	生体親和性薄膜を被覆した生体材料
KR20010018331A (ko) *	1999-08-18	2001-03-05	정태섭	알칼리 처리에 의한 생체용 임플란트의 생체활성 부여
JP2002035109A (ja) *	2000-07-21	2002-02-05	Tadashi Kokubo	抗血栓性材料及びその製造方法
KR100431159B1 (ko) *	2001-03-22	2004-05-12	김철생	생체활성 표면을 갖는 Ｔｉ-소재 경조직 대체재료의제조방법
JP4804648B2 (ja) *	2001-05-23	2011-11-02	株式会社神戸製鋼所	骨代替材料
US7291178B2 (en) *	2001-05-29	2007-11-06	Mediteam Dental Ab	Modified oxide
JP4911855B2 (ja) *	2001-10-17	2012-04-04	正小久保	生体親和性に優れた骨代替材料の製造方法
US7132015B2 (en) *	2002-02-20	2006-11-07	University Of Southern California	Materials for dental and biomedical application
US7410502B2 (en) *	2002-04-09	2008-08-12	Numat As	Medical prosthetic devices having improved biocompatibility
RU2313370C2 (ru) *	2002-04-09	2007-12-27	Астра Тек АБ	Медицинские протезы, имеющие улучшенную биологическую совместимость
JP3806061B2 (ja) *	2002-05-21	2006-08-09	富士通株式会社	金属修飾アパタイト含有膜の形成方法、これに用いられるコーティング液、および金属修飾アパタイト含有膜で被覆された部位を有する電子機器
US7740481B2 (en) *	2002-06-21	2010-06-22	Politecnico Di Milano	Osteointegrative interface for implantable prostheses and a method for the treatment of the osteointegrative interface
US20060122708A1 (en) *	2003-01-10	2006-06-08	Takashi Nakamura	Osteoinductive artificial bone and manufacturing method thereof
CN100367917C (zh) *	2003-04-11	2008-02-13	四川大学	表面骨诱导活性钛接骨板及其制造方法
WO2004103423A1 (en) *	2003-05-21	2004-12-02	Dentium Co., Ltd	Titanium substrate for biocompatible implant coated with hydroxyapatite/titania double layer and a coating method of the same
US7067169B2 (en) *	2003-06-04	2006-06-27	Chemat Technology Inc.	Coated implants and methods of coating
CN100421734C (zh) *	2005-04-26	2008-10-01	中国科学院金属研究所	一种快速制备钛或钛合金表面生物活性涂层的方法
CN101340935B (zh) *	2005-11-14	2013-05-08	拜奥美特3i有限责任公司	于植入物表面上淀积纳米粒子
US20070179618A1 (en) *	2006-01-31	2007-08-02	Sdgi Holdings, Inc.	Intervertebral prosthetic disc
US20070179615A1 (en) *	2006-01-31	2007-08-02	Sdgi Holdings, Inc.	Intervertebral prosthetic disc
WO2007090433A2 (en) *	2006-02-09	2007-08-16	Plus Orthopedics Ag	Purified oxides with novel morphologies formed from ti-alloys
JP5052506B2 (ja) *	2006-04-13	2012-10-17	佐川印刷株式会社	人工骨の製造方法
JP2008080102A (ja) *	2006-08-29	2008-04-10	Nagasaki Univ	インプラント
GB0624423D0 (en) *	2006-12-06	2007-01-17	Univ Brighton	Biomaterials with Functionalised Surfaces
WO2008081861A1 (ja) *	2006-12-28	2008-07-10	Saga University	チタネートでコーティングされた抗菌性部材
WO2008143219A1 (ja) *	2007-05-18	2008-11-27	National University Corporation Okayama University	生体親和性インプラントの製造方法
CA2696954C (en)	2007-08-20	2016-09-13	Smith & Nephew Plc	Implant material with an enlarged implant-to-bone interface layer and method of formation
AU2014268254B2 (en) *	2007-08-20	2015-11-05	Smith & Nephew Plc	Bioactive material
ITTO20070719A1 (it)	2007-10-12	2009-04-13	Torino Politecnico	Superfici di titanio multifunzionali per osteointegrazione.
EP2240116B1 (de)	2008-01-28	2015-07-01	Biomet 3I, LLC	Implantatoberfläche mit erhöhter hydrophilie
WO2009147819A1 (ja)	2008-06-03	2009-12-10	学校法人中部大学	骨修復材料及びその製造方法
IT1390847B1 (it)	2008-07-29	2011-10-19	Milano Politecnico	Trattamento biomimetico a base silicio per l'osteointegrazione di substrati in metallo.
EP2392357B1 (de)	2009-01-30	2016-01-27	Chubu University Educational Foundation	Material für knochenreparatur und verfahren zu seiner herstellung
JP2013508262A (ja)	2009-10-26	2013-03-07	ラトガース，ザステートユニバーシティオブニュージャージー	制御可能なサイズおよび形態を有するハイドロキシアパタイト
US8641418B2 (en)	2010-03-29	2014-02-04	Biomet 3I, Llc	Titanium nano-scale etching on an implant surface
ES2671740T3 (es)	2012-03-20	2018-06-08	Biomet 3I, Llc	Superficie de tratamiento para una superficie de implante
JP2013236700A (ja) *	2012-05-14	2013-11-28	Chube Univ	抗菌性骨修復材料及びその製造方法
WO2013180237A1 (ja) *	2012-05-30	2013-12-05	京セラメディカル株式会社	歯科インプラント
JP6206880B2 (ja) *	2012-08-16	2017-10-04	学校法人中部大学	骨修復材料及びその製造方法
CN105126176B (zh) *	2015-09-21	2018-07-24	高瑞杰	一种用于股骨修复的牡蛎壳生物相容仿生材料以及制备方法
CN109701082B (zh) *	2019-02-22	2021-10-08	九江学院	一种羟基磷灰石-氢氧化钛复合粉体的制备方法和应用

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JPS5214095A (en) *	1975-07-23	1977-02-02	Sumitomo Chemical Co	Implant in bone
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1994
- 1994-11-07 AU AU81157/94A patent/AU671567B2/en not_active Ceased
- 1994-11-07 CN CN94190749A patent/CN1101705C/zh not_active Expired - Lifetime
- 1994-11-07 KR KR1019950702262A patent/KR0149134B1/ko not_active Expired - Lifetime
- 1994-11-07 CA CA002150036A patent/CA2150036C/en not_active Expired - Fee Related
- 1994-11-07 EP EP95900273A patent/EP0678300B1/de not_active Expired - Lifetime
- 1994-11-07 WO PCT/JP1994/001885 patent/WO1995013100A1/ja not_active Ceased
- 1994-11-07 AT AT95900273T patent/ATE191856T1/de active
- 1994-11-07 PT PT95900273T patent/PT678300E/pt unknown
- 1994-11-07 ES ES95900273T patent/ES2147831T3/es not_active Expired - Lifetime
- 1994-11-07 DK DK95900273T patent/DK0678300T3/da active
- 1994-11-07 DE DE69424035T patent/DE69424035T2/de not_active Expired - Lifetime
- 1994-11-07 KR KR1019950702262A patent/KR950704004A/ko active Granted
- 1994-11-09 US US08/338,171 patent/US5609633A/en not_active Expired - Lifetime
1995
- 1995-04-25 NO NO951567A patent/NO310060B1/no not_active IP Right Cessation
- 1995-05-09 FI FI952234A patent/FI115445B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI952234A0 (fi)	1995-05-09
AU671567B2 (en)	1996-08-29
KR950704004A (ko)	1995-11-17
CN1115170A (zh)	1996-01-17
DK0678300T3 (da)	2000-07-17
NO951567D0 (no)	1995-04-25
FI952234L (fi)	1995-05-10
CA2150036A1 (en)	1995-05-18
AU8115794A (en)	1995-05-29
ATE191856T1 (de)	2000-05-15
CA2150036C (en)	2001-07-10
WO1995013100A1 (en)	1995-05-18
DE69424035D1 (de)	2000-05-25
DE69424035T2 (de)	2000-12-14
EP0678300B1 (de)	2000-04-19
NO951567L (no)	1995-05-18
CN1101705C (zh)	2003-02-19
PT678300E (pt)	2000-11-30
KR0149134B1 (ko)	1998-10-01
EP0678300A1 (de)	1995-10-25
US5609633A (en)	1997-03-11
ES2147831T3 (es)	2000-10-01
FI115445B (fi)	2005-05-13
EP0678300A4 (de)	1996-04-03

Legal Events

Date	Code	Title	Description
2012-06-25	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO310060B1 (no)	2001-05-14	Materiale for ben-erstatning og fremstilling derav
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US20050221259A1 (en)	2005-10-06	Dental or orthopaedic implant
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