NO314308B1 - Biotin-innholdende chemiluminiserende markör, anvendelse av markören for fremstilling av en diagnostisk analyse, diagnostisk analyse og settfor diagnostisk analysering - Google Patents

Biotin-innholdende chemiluminiserende markör, anvendelse av markören for fremstilling av en diagnostisk analyse, diagnostisk analyse og settfor diagnostisk analysering Download PDF

Info

Publication number: NO314308B1
Authority: NO; Norway
Prior art keywords: chemiluminescent; analyte; marker; assay; conjugate
Prior art date: 1992-08-21

Application number

NO19950632A

Other languages

English (en)

Norwegian (no)

Other versions

NO950632L (no

NO950632D0 (no

Inventor

Kastooriranganath Remakrishnan

Original Assignee

Nichols Inst Diagnostics

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-08-21

Filing date

1995-02-20

Publication date

2003-03-03

1995-02-20 Application filed by Nichols Inst Diagnostics filed Critical Nichols Inst Diagnostics

1995-02-20 Publication of NO950632D0 publication Critical patent/NO950632D0/no

1995-04-07 Publication of NO950632L publication Critical patent/NO950632L/no

2003-03-03 Publication of NO314308B1 publication Critical patent/NO314308B1/no

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239000000700 radioactive tracer Substances 0.000 description 1
239000012429 reaction media Substances 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
238000011160 research Methods 0.000 description 1
238000012552 review Methods 0.000 description 1
239000012488 sample solution Substances 0.000 description 1
229960001153 serine Drugs 0.000 description 1
235000004400 serine Nutrition 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
238000001542 size-exclusion chromatography Methods 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000000638 solvent extraction Methods 0.000 description 1
150000003431 steroids Chemical class 0.000 description 1
229940124530 sulfonamide Drugs 0.000 description 1
150000003456 sulfonamides Chemical class 0.000 description 1
150000003573 thiols Chemical class 0.000 description 1
229960002898 threonine Drugs 0.000 description 1
235000008521 threonine Nutrition 0.000 description 1
125000003944 tolyl group Chemical group 0.000 description 1
229960004799 tryptophan Drugs 0.000 description 1
229960004441 tyrosine Drugs 0.000 description 1
235000002374 tyrosine Nutrition 0.000 description 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
229960004295 valine Drugs 0.000 description 1
239000004474 valine Substances 0.000 description 1
235000019156 vitamin B Nutrition 0.000 description 1
239000011720 vitamin B Substances 0.000 description 1
229940046001 vitamin b complex Drugs 0.000 description 1
125000005023 xylyl group Chemical group 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Food Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Biotechnology (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

NO19950632A 1992-08-21 1995-02-20 Biotin-innholdende chemiluminiserende markör, anvendelse av markören for fremstilling av en diagnostisk analyse, diagnostisk analyse og settfor diagnostisk analysering NO314308B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/933,478 US5395938A (en)	1992-08-21	1992-08-21	Biotinylated chemiluminescent labels and their conjugates, assays and assay kits
PCT/US1993/007896 WO1994004538A1 (en)	1992-08-21	1993-08-19	Biotinylated chemiluminescent labels, conjugates, assays, assay kits

Publications (3)

Publication Number	Publication Date
NO950632D0 NO950632D0 (no)	1995-02-20
NO950632L NO950632L (no)	1995-04-07
NO314308B1 true NO314308B1 (no)	2003-03-03

Family

ID=25464042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19950632A NO314308B1 (no)	1992-08-21	1995-02-20	Biotin-innholdende chemiluminiserende markör, anvendelse av markören for fremstilling av en diagnostisk analyse, diagnostisk analyse og settfor diagnostisk analysering

Country Status (12)

Country	Link
US (1)	US5395938A (de)
EP (1)	EP0656005B1 (de)
JP (1)	JP4068137B2 (de)
AT (1)	ATE238309T1 (de)
AU (1)	AU677017B2 (de)
CA (1)	CA2142867C (de)
DE (1)	DE69332903T2 (de)
ES (1)	ES2198417T3 (de)
FI (1)	FI111946B (de)
NO (1)	NO314308B1 (de)
NZ (1)	NZ255853A (de)
WO (1)	WO1994004538A1 (de)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE111083T1 (de) *	1986-10-22	1994-09-15	Abbott Lab	Chemilumineszierende acridinium- und phenantridiniumsalze.
US6087188A (en) *	1992-11-13	2000-07-11	Alk A/S	Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand
DE4407423A1 (de) *	1994-03-05	1995-09-07	Boehringer Mannheim Gmbh	Entstörmittel zum Einsatz bei Immunoassays
GB2289334B (en) *	1994-05-10	1998-08-26	Molecular Light Technology Lim	Enzyme linked chemiluminescent assay
US5663054A (en) *	1995-03-03	1997-09-02	Abbott Laboratories	Determination of steroids by competitive immunoassay
US6056923A (en) *	1997-06-25	2000-05-02	Clmp, Inc.	Dual injector for chemiluminescence immunoanalyzing system
FR2781802B1 (fr) *	1998-07-31	2001-05-11	Bio Merieux	Derives satures ou insatures de l'abietane, conjugues derives et utilisations dans une composition diagnostique, un reactif et un dispositif
KR20000074881A (ko) *	1999-05-26	2000-12-15	황승용	마이크로웰을 이용한 디엔에이 돌연변이의 확인방법 및 키트
US7087395B1 (en)	2001-01-16	2006-08-08	Quest Diagnostics Investments Incorporated	Vitamin D assay
US20030082179A1 (en) *	2001-07-03	2003-05-01	Hutchison James Scott	Parathyroid hormone antibodies and related methods
US6723851B2 (en)	2001-10-31	2004-04-20	Quest Diagnostics Investment Incorporated	Chemiluminescent compounds and use thereof
US20050042632A1 (en) *	2002-02-13	2005-02-24	Sirna Therapeutics, Inc.	Antibodies having specificity for nucleic acids
US7071311B2 (en) *	2002-02-13	2006-07-04	Sirna Therapeutics, Inc.	Antibodies having specificity for 2′-C-allyl nucleic acids
US6924154B2 (en)	2002-08-20	2005-08-02	Quest Diagnostics Investments Incorporated	Hydrophilic chemilumescent acridinium labeling reagents
ATE553089T1 (de) *	2002-08-20	2012-04-15	Quest Diagnostics Invest Inc	Hydrophile, chemilumineszente acridiniummarkierungsreagenzien
US20050112586A1 (en) *	2003-11-24	2005-05-26	Roland Janzen	Method and composition for stabilizing liquid reagents
KR100778633B1 (ko)	2007-04-13	2007-11-28	성균관대학교산학협력단	비오틴과 비오틴-폴리에틸렌글리콜이 접합된 ｇｌｐ-1유도체, 이의 제조방법 및 이를 포함하는 약학 조성물
US9075055B2 (en)	2013-03-15	2015-07-07	Hycor Biomedical, Inc.	Device and associated methods for performing luminescence and fluorescence measurements of a sample

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4363759A (en) *	1978-04-10	1982-12-14	Miles Laboratories, Inc.	Chemiluminescent-labeled haptens and antigens
US4656252A (en) *	1980-01-24	1987-04-07	Giese Roger W	Amidobiotin compounds useful in a avidin-biotin multiple layering process
EP0082636B2 (de) *	1981-12-11	2006-10-18	The Welsh National School of Medicine	Lumineszierende Markierungssubstanzen und -verfahren
US4687747A (en) *	1984-07-02	1987-08-18	Mallinckrodt, Inc.	Phenanthridinium ester as a labelling compound in luminometric immunoassay
DE3601031A1 (de) *	1986-01-16	1987-07-23	Behringwerke Ag	Maleimido-derivate von biotin-hydrazid, verfahren zu ihrer herstellung und ihre verwendung
US4709037A (en) *	1987-02-17	1987-11-24	Hoechst Celanese Corporation	Biotinylating agents
US5180828A (en) *	1990-02-09	1993-01-19	Molecular Devices Corporation	Chromophoric reagents for incorporation of biotin or other haptens into macromolecules
DE473984T1 (de) *	1990-09-07	1992-08-13	The Board Of Governors Of Wayne State University, Detroit, Mich.	1,2-dioxetan-verbindungen als chemilumineszierende markierungen fuer organische und biologische molekuele.
US5162352A (en) *	1991-08-22	1992-11-10	E. R. Squibb & Sons, Inc.	7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs

1992
- 1992-08-21 US US07/933,478 patent/US5395938A/en not_active Expired - Lifetime
1993
- 1993-08-19 DE DE69332903T patent/DE69332903T2/de not_active Expired - Lifetime
- 1993-08-19 CA CA2142867A patent/CA2142867C/en not_active Expired - Lifetime
- 1993-08-19 NZ NZ255853A patent/NZ255853A/en not_active IP Right Cessation
- 1993-08-19 ES ES94908153T patent/ES2198417T3/es not_active Expired - Lifetime
- 1993-08-19 EP EP94908153A patent/EP0656005B1/de not_active Expired - Lifetime
- 1993-08-19 AT AT94908153T patent/ATE238309T1/de not_active IP Right Cessation
- 1993-08-19 JP JP50657494A patent/JP4068137B2/ja not_active Expired - Lifetime
- 1993-08-19 AU AU50864/93A patent/AU677017B2/en not_active Expired
- 1993-08-19 WO PCT/US1993/007896 patent/WO1994004538A1/en not_active Ceased
1995
- 1995-02-20 FI FI950764A patent/FI111946B/fi not_active IP Right Cessation
- 1995-02-20 NO NO19950632A patent/NO314308B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO950632L (no)	1995-04-07
ATE238309T1 (de)	2003-05-15
JP4068137B2 (ja)	2008-03-26
FI950764L (fi)	1995-04-20
AU5086493A (en)	1994-03-15
JPH08504751A (ja)	1996-05-21
DE69332903D1 (de)	2003-05-28
FI950764A0 (fi)	1995-02-20
CA2142867C (en)	2010-03-16
CA2142867A1 (en)	1994-03-03
US5395938A (en)	1995-03-07
NO950632D0 (no)	1995-02-20
NZ255853A (en)	1997-05-26
FI111946B (fi)	2003-10-15
EP0656005B1 (de)	2003-04-23
DE69332903T2 (de)	2004-03-04
AU677017B2 (en)	1997-04-10
EP0656005A1 (de)	1995-06-07
WO1994004538A1 (en)	1994-03-03
EP0656005A4 (de)	1995-07-26
ES2198417T3 (es)	2004-02-01

Legal Events

Date	Code	Title	Description
2013-10-07	MK1K	Patent expired

Publication	Publication Date	Title
NO314308B1 (no)	2003-03-03	Biotin-innholdende chemiluminiserende markör, anvendelse av markören for fremstilling av en diagnostisk analyse, diagnostisk analyse og settfor diagnostisk analysering
US5281712A (en)	1994-01-25	Ammonium substituted chemiluminescent labels and their conjugates, and assays therefrom
US20110014721A1 (en)	2011-01-20	Hydrophilic chemiluminescent acridinium labeling reagents
US6162610A (en)	2000-12-19	Xanthan-ester and acridan substrates for horseradish peroxidase
JP2604993B2 (ja)	1997-04-30	新規なビオチン化試薬
JP4699756B2 (ja)	2011-06-15	親水性化学発光アクリジニウムラベル化剤
US5321136A (en)	1994-06-14	Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
US5338847A (en)	1994-08-16	Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation
US6171520B1 (en)	2001-01-09	Reagents for labeling SH groups, process for the preparation of them and method for labeling with them
CN114778816A (zh)	2022-07-22	一种吖啶酯标记复合物及制备方法
EP2457916A1 (de)	2012-05-30	Verbindung zur kovalenten Anheftung der chemolumineszenten Sonde N-(4-Aminobutyl)-N-ethylisoluminol (ABEI) zur Bestimmung von Molekülen und Verwendungen dafür
JP3174729B2 (ja)	2001-06-11	アクリジン誘導体、その製法およびこれを用いた標識法
CN119775256B (zh)	2025-09-19	吖啶磺酰胺衍生物、制备方法、其应用及试剂盒
JPH06316599A (ja)	1994-11-15	ジフェンヒドラミンおよびその代謝産物の免疫学的測定のための組成物および方法
EP0079489A1 (de)	1983-05-25	Methotrexat markierte Jodthyronin-Konjugate und Verfahren, Reagenz und Testeinrichtung zum Nachweis von Jodthyronin oder der Jodthyronin-Aufnahme einer Flüssigkeit
JP2002195999A (ja)	2002-07-10	有機ハロゲン化合物の免疫測定方法