ATE238309T1 - Biotinylierte, chemolumineszente label, konjugate,assays sowie assay kits - Google Patents

Biotinylierte, chemolumineszente label, konjugate,assays sowie assay kits

Info

Publication number: ATE238309T1
Authority: AT; Austria
Prior art keywords: assays; conjugates; streptavidin; avidin; biotinylated
Prior art date: 1992-08-21

Application number

AT94908153T

Other languages

English (en)

Inventor

Kastooriranganath Remakrishnan

Original Assignee

Nichols Inst Diagnostics

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-08-21

Filing date

1993-08-19

Publication date

2003-05-15

1993-08-19 Application filed by Nichols Inst Diagnostics filed Critical Nichols Inst Diagnostics

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE238309T1 publication Critical patent/ATE238309T1/de

Links

238000003556 assay Methods 0.000 title abstract 5
238000003149 assay kit Methods 0.000 title 1
108090001008 Avidin Proteins 0.000 abstract 3
108010090804 Streptavidin Proteins 0.000 abstract 3
YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical group N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 abstract 2
239000012491 analyte Substances 0.000 abstract 1
229960002685 biotin Drugs 0.000 abstract 1
235000020958 biotin Nutrition 0.000 abstract 1
239000011616 biotin Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
238000002372 labelling Methods 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Immunology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT94908153T 1992-08-21 1993-08-19 Biotinylierte, chemolumineszente label, konjugate,assays sowie assay kits ATE238309T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/933,478 US5395938A (en)	1992-08-21	1992-08-21	Biotinylated chemiluminescent labels and their conjugates, assays and assay kits
PCT/US1993/007896 WO1994004538A1 (en)	1992-08-21	1993-08-19	Biotinylated chemiluminescent labels, conjugates, assays, assay kits

Publications (1)

Publication Number	Publication Date
ATE238309T1 true ATE238309T1 (de)	2003-05-15

Family

ID=25464042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94908153T ATE238309T1 (de)	1992-08-21	1993-08-19	Biotinylierte, chemolumineszente label, konjugate,assays sowie assay kits

Country Status (12)

Country	Link
US (1)	US5395938A (de)
EP (1)	EP0656005B1 (de)
JP (1)	JP4068137B2 (de)
AT (1)	ATE238309T1 (de)
AU (1)	AU677017B2 (de)
CA (1)	CA2142867C (de)
DE (1)	DE69332903T2 (de)
ES (1)	ES2198417T3 (de)
FI (1)	FI111946B (de)
NO (1)	NO314308B1 (de)
NZ (1)	NZ255853A (de)
WO (1)	WO1994004538A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3750503T2 (de) *	1986-10-22	1995-02-09	Abbott Lab	Chemilumineszierende Acridinium- und Phenantridiniumsalze.
US6087188A (en) *	1992-11-13	2000-07-11	Alk A/S	Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand
DE4407423A1 (de) *	1994-03-05	1995-09-07	Boehringer Mannheim Gmbh	Entstörmittel zum Einsatz bei Immunoassays
GB2289334B (en) *	1994-05-10	1998-08-26	Molecular Light Technology Lim	Enzyme linked chemiluminescent assay
US5663054A (en)	1995-03-03	1997-09-02	Abbott Laboratories	Determination of steroids by competitive immunoassay
US6056923A (en) *	1997-06-25	2000-05-02	Clmp, Inc.	Dual injector for chemiluminescence immunoanalyzing system
FR2781802B1 (fr) *	1998-07-31	2001-05-11	Bio Merieux	Derives satures ou insatures de l'abietane, conjugues derives et utilisations dans une composition diagnostique, un reactif et un dispositif
KR20000074881A (ko) *	1999-05-26	2000-12-15	황승용	마이크로웰을 이용한 디엔에이 돌연변이의 확인방법 및 키트
US7087395B1 (en)	2001-01-16	2006-08-08	Quest Diagnostics Investments Incorporated	Vitamin D assay
US20030082179A1 (en) *	2001-07-03	2003-05-01	Hutchison James Scott	Parathyroid hormone antibodies and related methods
US6723851B2 (en)	2001-10-31	2004-04-20	Quest Diagnostics Investment Incorporated	Chemiluminescent compounds and use thereof
US7071311B2 (en) *	2002-02-13	2006-07-04	Sirna Therapeutics, Inc.	Antibodies having specificity for 2′-C-allyl nucleic acids
US20050042632A1 (en) *	2002-02-13	2005-02-24	Sirna Therapeutics, Inc.	Antibodies having specificity for nucleic acids
ATE553089T1 (de) *	2002-08-20	2012-04-15	Quest Diagnostics Invest Inc	Hydrophile, chemilumineszente acridiniummarkierungsreagenzien
US6924154B2 (en)	2002-08-20	2005-08-02	Quest Diagnostics Investments Incorporated	Hydrophilic chemilumescent acridinium labeling reagents
US20050112586A1 (en) *	2003-11-24	2005-05-26	Roland Janzen	Method and composition for stabilizing liquid reagents
KR100778633B1 (ko)	2007-04-13	2007-11-28	성균관대학교산학협력단	비오틴과 비오틴-폴리에틸렌글리콜이 접합된 ｇｌｐ-1유도체, 이의 제조방법 및 이를 포함하는 약학 조성물
HK1220759A1 (zh)	2013-03-15	2017-05-12	Hycor Biomedical Llc	用於进行过敏症和自身免疫性疾病的诊断测定的自动化免疫分析系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4363759A (en) *	1978-04-10	1982-12-14	Miles Laboratories, Inc.	Chemiluminescent-labeled haptens and antigens
US4656252A (en) *	1980-01-24	1987-04-07	Giese Roger W	Amidobiotin compounds useful in a avidin-biotin multiple layering process
DE3279029D1 (en) *	1981-12-11	1988-10-20	Welsh Nat School Med	Luminescent labelling materials and procedures
US4687747A (en) *	1984-07-02	1987-08-18	Mallinckrodt, Inc.	Phenanthridinium ester as a labelling compound in luminometric immunoassay
DE3601031A1 (de) *	1986-01-16	1987-07-23	Behringwerke Ag	Maleimido-derivate von biotin-hydrazid, verfahren zu ihrer herstellung und ihre verwendung
US4709037A (en) *	1987-02-17	1987-11-24	Hoechst Celanese Corporation	Biotinylating agents
US5180828A (en) *	1990-02-09	1993-01-19	Molecular Devices Corporation	Chromophoric reagents for incorporation of biotin or other haptens into macromolecules
EP0473984A1 (de) *	1990-09-07	1992-03-11	The Board Of Governors Of Wayne State University	1,2-Dioxetan-Verbindungen als chemilumineszierende Markierungen für organische und biologische Moleküle
US5162352A (en) *	1991-08-22	1992-11-10	E. R. Squibb & Sons, Inc.	7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs

1992
- 1992-08-21 US US07/933,478 patent/US5395938A/en not_active Expired - Lifetime
1993
- 1993-08-19 AU AU50864/93A patent/AU677017B2/en not_active Expired
- 1993-08-19 CA CA2142867A patent/CA2142867C/en not_active Expired - Lifetime
- 1993-08-19 WO PCT/US1993/007896 patent/WO1994004538A1/en not_active Ceased
- 1993-08-19 DE DE69332903T patent/DE69332903T2/de not_active Expired - Lifetime
- 1993-08-19 ES ES94908153T patent/ES2198417T3/es not_active Expired - Lifetime
- 1993-08-19 AT AT94908153T patent/ATE238309T1/de not_active IP Right Cessation
- 1993-08-19 NZ NZ255853A patent/NZ255853A/en not_active IP Right Cessation
- 1993-08-19 EP EP94908153A patent/EP0656005B1/de not_active Expired - Lifetime
- 1993-08-19 JP JP50657494A patent/JP4068137B2/ja not_active Expired - Lifetime
1995
- 1995-02-20 FI FI950764A patent/FI111946B/fi not_active IP Right Cessation
- 1995-02-20 NO NO19950632A patent/NO314308B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
US5395938A (en)	1995-03-07
DE69332903D1 (de)	2003-05-28
JPH08504751A (ja)	1996-05-21
EP0656005A1 (de)	1995-06-07
CA2142867A1 (en)	1994-03-03
AU677017B2 (en)	1997-04-10
FI111946B (fi)	2003-10-15
NO314308B1 (no)	2003-03-03
CA2142867C (en)	2010-03-16
JP4068137B2 (ja)	2008-03-26
DE69332903T2 (de)	2004-03-04
FI950764L (fi)	1995-04-20
AU5086493A (en)	1994-03-15
NZ255853A (en)	1997-05-26
EP0656005A4 (de)	1995-07-26
EP0656005B1 (de)	2003-04-23
WO1994004538A1 (en)	1994-03-03
NO950632D0 (no)	1995-02-20
ES2198417T3 (es)	2004-02-01
FI950764A0 (fi)	1995-02-20
NO950632L (no)	1995-04-07

Legal Events

Date	Code	Title	Description
2003-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69332903D1 (de)	2003-05-28	Biotinylierte, chemolumineszente label, konjugate, assays sowie assay kits
CA2210888A1 (en)	1996-07-25	Fluorescent petroleum markers
HN1998000118A (es)	1999-02-09	2 - aminopiridinas que contienen sustituyentes de anillos condensados.
HN1998000011A (es)	1999-02-09	Derivados de acidos arilsulfonilaminohidroxamicos
DE69737683D1 (de)	2007-06-14	Antikörper gegen die ed-b domäne von fibronektin, ihre herstellung und verwendungen
KR880701379A (ko)	1988-07-26	전기 화학 발광 분석법
DE69432589D1 (de)	2003-06-05	Substrate für die übertragung von fluoreszenzenergie
ATE50066T1 (de)	1990-02-15	Gleichseitige mehrfache proben und in denselben zu verwendende zusammensetzungen.
WO1996032004A3 (en)	1996-11-14	Chemiluminescent immunoassay for antibody detection
MXPA04001730A (es)	2004-05-31	Metodo para determinacion de multiples analitos.
MX9207137A (es)	1993-08-01	Nuevos oligodesoxirribonucleotidos, que tienen una actividad anti-isquemica, y metodos para su preparacion
AU3030195A (en)	1996-03-14	Chemiluminescent reagent and assay using a substituted acetanilide for light generation
DE68929213D1 (de)	2000-06-21	Immunoessay auf einer vorbeschichteten festen Oberfläche
ES2103559T3 (es)	1997-09-16	Inmunoensayo de dos sitios para un anticuerpo con marcado luminiscente y ligando unido a biotina.
AU3745799A (en)	1999-11-01	Assays for the detection of microtubule depolymerization inhibitors
SE8802478L (sv)	1989-01-03	Foerfarande foer fluorescent maerkning av sockerarter
DE60017019D1 (de)	2005-02-03	Antikörper gegen Spaltprodukte von Vimentin
BR9609390A (pt)	1999-05-18	Ensaio quimiluminescente de ligação específica com não-separação
AU2002245206A1 (en)	2002-07-30	Dendritic chemiluminescent substrates
CA2097545A1 (en)	1993-12-04	Process for the immunochemical determination of an analyte
EP1026156A3 (de)	2001-10-24	Neue 10, 10'-substituierte-9,9'-biacridin-Lumineszenz-Moleküle sowie ihrer Herstellung
AU3642701A (en)	2001-05-30	Hydrolytic enzyme substrates and assay method
FR2756827B1 (fr)	1999-01-29	Composes synthetiques biepitopiques utilisables comme etalons dans les dosages biologiques de la troponine i
WO1996041015A3 (en)	1997-05-01	Enhancement of alkaline phosphatase with sds in chemiluminescent substrates and enzyme inhibition assays
AU5305990A (en)	1990-10-11	Enzyme luminescence assay