NO315005B1 - Innretning for massedyrking av celler - Google Patents

Innretning for massedyrking av celler Download PDF

Info

Publication number: NO315005B1
Authority: NO; Norway
Prior art keywords: cell culture; carrier; oxygen; culture carrier; collagen layer
Prior art date: 1992-03-03

Application number

NO19943242A

Other languages

English (en)

Norwegian (no)

Other versions

NO943242D0 (no

NO943242L (no

Inventor

Augustinus Bader

Original Assignee

Organogenesis Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-03

Filing date

1994-09-01

Publication date

2003-06-23

1994-09-01 Application filed by Organogenesis Inc filed Critical Organogenesis Inc

1994-09-01 Publication of NO943242D0 publication Critical patent/NO943242D0/no

1994-09-01 Publication of NO943242L publication Critical patent/NO943242L/no

2003-06-23 Publication of NO315005B1 publication Critical patent/NO315005B1/no

Links

238000004113 cell culture Methods 0.000 claims abstract description 105
108010035532 Collagen Proteins 0.000 claims abstract description 48
102000008186 Collagen Human genes 0.000 claims abstract description 48
229920001436 collagen Polymers 0.000 claims abstract description 48
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 45
239000001301 oxygen Substances 0.000 claims abstract description 45
229910052760 oxygen Inorganic materials 0.000 claims abstract description 45
210000003494 hepatocyte Anatomy 0.000 claims abstract description 23
239000001963 growth medium Substances 0.000 claims abstract description 19
239000007789 gas Substances 0.000 claims abstract description 12
210000004027 cell Anatomy 0.000 claims description 27
239000000969 carrier Substances 0.000 claims description 20
239000002609 medium Substances 0.000 claims description 14
238000007789 sealing Methods 0.000 claims description 9
239000012528 membrane Substances 0.000 claims description 8
235000015097 nutrients Nutrition 0.000 claims description 8
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239000002184 metal Substances 0.000 claims description 7
239000004033 plastic Substances 0.000 claims description 7
229920001296 polysiloxane Polymers 0.000 claims description 7
210000004738 parenchymal cell Anatomy 0.000 claims description 6
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125000006850 spacer group Chemical group 0.000 claims description 5
239000006143 cell culture medium Substances 0.000 claims description 4
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238000002474 experimental method Methods 0.000 description 9
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CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 8
239000011159 matrix material Substances 0.000 description 7
239000002207 metabolite Substances 0.000 description 7
238000000034 method Methods 0.000 description 7
IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 6
239000003814 drug Substances 0.000 description 6
241000282412 Homo Species 0.000 description 5
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239000004809 Teflon Substances 0.000 description 2
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208000030507 AIDS Diseases 0.000 description 1
235000001674 Agaricus brunnescens Nutrition 0.000 description 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 description 1
108010036949 Cyclosporine Proteins 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
206010019695 Hepatic neoplasm Diseases 0.000 description 1
206010019851 Hepatotoxicity Diseases 0.000 description 1
206010067125 Liver injury Diseases 0.000 description 1
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208000012868 Overgrowth Diseases 0.000 description 1
241001504519 Papio ursinus Species 0.000 description 1
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241000288906 Primates Species 0.000 description 1
230000009471 action Effects 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
230000001154 acute effect Effects 0.000 description 1
210000004102 animal cell Anatomy 0.000 description 1
238000010171 animal model Methods 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
210000000941 bile Anatomy 0.000 description 1
230000023852 carbohydrate metabolic process Effects 0.000 description 1
235000021256 carbohydrate metabolism Nutrition 0.000 description 1
210000000845 cartilage Anatomy 0.000 description 1
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230000030833 cell death Effects 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
229960001265 ciclosporin Drugs 0.000 description 1
238000003776 cleavage reaction Methods 0.000 description 1
238000003501 co-culture Methods 0.000 description 1
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210000005260 human cell Anatomy 0.000 description 1
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238000002955 isolation Methods 0.000 description 1
210000003734 kidney Anatomy 0.000 description 1
150000002605 large molecules Chemical class 0.000 description 1
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238000002360 preparation method Methods 0.000 description 1
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238000005086 pumping Methods 0.000 description 1
238000004064 recycling Methods 0.000 description 1
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238000002271 resection Methods 0.000 description 1
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239000002356 single layer Substances 0.000 description 1
238000005245 sintering Methods 0.000 description 1
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231100000765 toxin Toxicity 0.000 description 1
108700012359 toxins Proteins 0.000 description 1
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230000000472 traumatic effect Effects 0.000 description 1
238000009827 uniform distribution Methods 0.000 description 1
238000009423 ventilation Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/04—Flat or tray type, drawers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/06—Plates; Walls; Drawers; Multilayer plates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis

Landscapes

Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Sustainable Development (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Clinical Laboratory Science (AREA)
Immunology (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Cultivation Receptacles Or Flower-Pots, Or Pots For Seedlings (AREA)

NO19943242A 1992-03-03 1994-09-01 Innretning for massedyrking av celler NO315005B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4206585A DE4206585C2 (de)	1992-03-03	1992-03-03	Vorrichtung zur Massenkultur von Zellen
PCT/EP1993/000468 WO1993018133A1 (fr)	1992-03-03	1993-03-02	Dispositif pour le traitement de cultures cellulaires

Publications (3)

Publication Number	Publication Date
NO943242D0 NO943242D0 (no)	1994-09-01
NO943242L NO943242L (no)	1994-09-01
NO315005B1 true NO315005B1 (no)	2003-06-23

Family

ID=6453071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19943242A NO315005B1 (no)	1992-03-03	1994-09-01	Innretning for massedyrking av celler

Country Status (12)

Country	Link
US (1)	US5658797A (fr)
EP (1)	EP0629237B1 (fr)
JP (1)	JP3176628B2 (fr)
AT (1)	ATE131867T1 (fr)
AU (1)	AU668922B2 (fr)
CA (1)	CA2129648C (fr)
DE (2)	DE4206585C2 (fr)
DK (1)	DK0629237T3 (fr)
ES (1)	ES2083851T3 (fr)
GR (1)	GR3019255T3 (fr)
NO (1)	NO315005B1 (fr)
WO (1)	WO1993018133A1 (fr)

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- 1992-03-03 DE DE4206585A patent/DE4206585C2/de not_active Expired - Fee Related
1993
- 1993-03-02 EP EP93906477A patent/EP0629237B1/fr not_active Expired - Lifetime
- 1993-03-02 AU AU37456/93A patent/AU668922B2/en not_active Ceased
- 1993-03-02 DE DE59301218T patent/DE59301218D1/de not_active Expired - Fee Related
- 1993-03-02 DK DK93906477.0T patent/DK0629237T3/da active
- 1993-03-02 AT AT93906477T patent/ATE131867T1/de not_active IP Right Cessation
- 1993-03-02 ES ES93906477T patent/ES2083851T3/es not_active Expired - Lifetime
- 1993-03-02 US US08/295,732 patent/US5658797A/en not_active Expired - Lifetime
- 1993-03-02 CA CA002129648A patent/CA2129648C/fr not_active Expired - Lifetime
- 1993-03-02 JP JP51530693A patent/JP3176628B2/ja not_active Expired - Fee Related
- 1993-03-02 WO PCT/EP1993/000468 patent/WO1993018133A1/fr not_active Ceased
1994
- 1994-09-01 NO NO19943242A patent/NO315005B1/no unknown
1996
- 1996-03-11 GR GR960400654T patent/GR3019255T3/el unknown

Also Published As

Publication number	Publication date
JPH07504325A (ja)	1995-05-18
CA2129648C (fr)	2009-08-11
JP3176628B2 (ja)	2001-06-18
ES2083851T3 (es)	1996-04-16
AU668922B2 (en)	1996-05-23
GR3019255T3 (en)	1996-06-30
EP0629237B1 (fr)	1995-12-20
US5658797A (en)	1997-08-19
DE4206585C2 (de)	1994-11-24
NO943242D0 (no)	1994-09-01
DK0629237T3 (da)	1996-04-09
WO1993018133A1 (fr)	1993-09-16
DE59301218D1 (de)	1996-02-01
ATE131867T1 (de)	1996-01-15
CA2129648A1 (fr)	1993-09-16
DE4206585A1 (de)	1993-09-09
NO943242L (no)	1994-09-01
AU3745693A (en)	1993-10-05
EP0629237A1 (fr)	1994-12-21

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