NO322252B1 - Anti-EGFR-enkeltkjede-Fv-er, DNA-molekyl som koder for denne, fremgangsmate for fremstilling av denne, kimert anti-EGFR-antistoff, fremgangsmate for fremstilling av helt kimert anti-EGFR-antistoff, farmasoytisk preparat som omfatter disse og anvendelse av disse for fremstilling av legemiddel mot tumorer. - Google Patents

Anti-EGFR-enkeltkjede-Fv-er, DNA-molekyl som koder for denne, fremgangsmate for fremstilling av denne, kimert anti-EGFR-antistoff, fremgangsmate for fremstilling av helt kimert anti-EGFR-antistoff, farmasoytisk preparat som omfatter disse og anvendelse av disse for fremstilling av legemiddel mot tumorer. Download PDF

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Publication number
NO322252B1
NO322252B1 NO19954626A NO954626A NO322252B1 NO 322252 B1 NO322252 B1 NO 322252B1 NO 19954626 A NO19954626 A NO 19954626A NO 954626 A NO954626 A NO 954626A NO 322252 B1 NO322252 B1 NO 322252B1
Authority
NO
Norway
Prior art keywords
egfr
chain
antibody
cells
light chain
Prior art date
Application number
NO19954626A
Other languages
English (en)
Norwegian (no)
Other versions
NO954626D0 (no
NO954626L (no
Inventor
Mary M Bendig
Cathrine A Kettleborough
Keith H Ansell
Detlef Guessow
Jaume Adan
Francesc Mitjans
Elisabet Rosell
Francesc Blasco
Jaume Piulats
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO954626D0 publication Critical patent/NO954626D0/no
Publication of NO954626L publication Critical patent/NO954626L/no
Publication of NO322252B1 publication Critical patent/NO322252B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19954626A 1994-03-17 1995-11-16 Anti-EGFR-enkeltkjede-Fv-er, DNA-molekyl som koder for denne, fremgangsmate for fremstilling av denne, kimert anti-EGFR-antistoff, fremgangsmate for fremstilling av helt kimert anti-EGFR-antistoff, farmasoytisk preparat som omfatter disse og anvendelse av disse for fremstilling av legemiddel mot tumorer. NO322252B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94104160 1994-03-17
EP94118970 1994-12-02
PCT/EP1995/000978 WO1995025167A1 (en) 1994-03-17 1995-03-16 Anti-egfr single-chain fvs and anti-egfr antibodies

Publications (3)

Publication Number Publication Date
NO954626D0 NO954626D0 (no) 1995-11-16
NO954626L NO954626L (no) 1995-11-16
NO322252B1 true NO322252B1 (no) 2006-09-04

Family

ID=26135522

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19954626A NO322252B1 (no) 1994-03-17 1995-11-16 Anti-EGFR-enkeltkjede-Fv-er, DNA-molekyl som koder for denne, fremgangsmate for fremstilling av denne, kimert anti-EGFR-antistoff, fremgangsmate for fremstilling av helt kimert anti-EGFR-antistoff, farmasoytisk preparat som omfatter disse og anvendelse av disse for fremstilling av legemiddel mot tumorer.

Country Status (20)

Country Link
US (1) US5844093A (de)
EP (1) EP0699237B1 (de)
JP (2) JPH08510922A (de)
KR (1) KR100376038B1 (de)
AT (1) ATE232902T1 (de)
AU (1) AU2071695A (de)
CA (1) CA2163012C (de)
CZ (1) CZ292061B6 (de)
DE (1) DE69529649T2 (de)
DK (1) DK0699237T3 (de)
ES (1) ES2191702T3 (de)
HU (1) HU221001B1 (de)
MX (1) MX9504802A (de)
NO (1) NO322252B1 (de)
PL (1) PL181342B1 (de)
PT (1) PT699237E (de)
RU (1) RU2170257C2 (de)
SK (1) SK283889B6 (de)
UA (1) UA41929C2 (de)
WO (1) WO1995025167A1 (de)

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US5844093A (en) 1998-12-01
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