NO323696B1 - Anvendelse av sentrale cannabinoid-reseptor-antagonister for regulering av appetitt - Google Patents

Anvendelse av sentrale cannabinoid-reseptor-antagonister for regulering av appetitt Download PDF

Info

Publication number: NO323696B1
Authority: NO; Norway
Prior art keywords: receptor antagonists; alcohol; administration; cannabinoid receptor; receptor antagonist
Prior art date: 1997-01-28

Application number

NO19993634A

Other languages

English (en)

Norwegian (no)

Other versions

NO993634D0 (no

NO993634L (no

Inventor

Philippe Soubrie

Jeanne Maruani

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-28

Filing date

1999-07-27

Publication date

2007-06-25

1999-07-27 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

1999-07-27 Publication of NO993634D0 publication Critical patent/NO993634D0/no

1999-09-27 Publication of NO993634L publication Critical patent/NO993634L/no

2007-06-25 Publication of NO323696B1 publication Critical patent/NO323696B1/no

Links

229940122820 Cannabinoid receptor antagonist Drugs 0.000 title description 4
239000003536 cannabinoid receptor antagonist Substances 0.000 title description 4
235000021407 appetite control Nutrition 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 claims description 14
239000002464 receptor antagonist Substances 0.000 claims description 14
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 13
239000003814 drug Substances 0.000 claims description 13
235000019441 ethanol Nutrition 0.000 claims description 13
JZCPYUJPEARBJL-UHFFFAOYSA-N rimonabant Chemical compound CC=1C(C(=O)NN2CCCCC2)=NN(C=2C(=CC(Cl)=CC=2)Cl)C=1C1=CC=C(Cl)C=C1 JZCPYUJPEARBJL-UHFFFAOYSA-N 0.000 claims description 13
229940079593 drug Drugs 0.000 claims description 12
238000011282 treatment Methods 0.000 claims description 10
208000019454 Feeding and Eating disease Diseases 0.000 claims description 9
239000000126 substance Substances 0.000 claims description 9
208000030814 Eating disease Diseases 0.000 claims description 8
235000014632 disordered eating Nutrition 0.000 claims description 8
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150000001720 carbohydrates Chemical class 0.000 claims description 5
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238000004519 manufacturing process Methods 0.000 claims description 4
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GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
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FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
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229920002472 Starch Polymers 0.000 description 1
HQVHOQAKMCMIIM-HXUWFJFHSA-N WIN 55212-2 Chemical compound C([C@@H]1COC=2C=CC=C3C(C(=O)C=4C5=CC=CC=C5C=CC=4)=C(N1C3=2)C)N1CCOCC1 HQVHOQAKMCMIIM-HXUWFJFHSA-N 0.000 description 1
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201000011510 cancer Diseases 0.000 description 1
229930003827 cannabinoid Natural products 0.000 description 1
239000003557 cannabinoid Substances 0.000 description 1
239000003555 cannabinoid 1 receptor antagonist Substances 0.000 description 1
229940065144 cannabinoids Drugs 0.000 description 1
239000000969 carrier Substances 0.000 description 1
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238000012512 characterization method Methods 0.000 description 1
230000001684 chronic effect Effects 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Addiction (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Hematology (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO19993634A 1997-01-28 1999-07-27 Anvendelse av sentrale cannabinoid-reseptor-antagonister for regulering av appetitt NO323696B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9700870A FR2758723B1 (fr)	1997-01-28	1997-01-28	Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments
PCT/FR1998/000154 WO1998032441A1 (fr)	1997-01-28	1998-01-28	Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour reguler l'appetance

Publications (3)

Publication Number	Publication Date
NO993634D0 NO993634D0 (no)	1999-07-27
NO993634L NO993634L (no)	1999-09-27
NO323696B1 true NO323696B1 (no)	2007-06-25

Family

ID=9503028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19993634A NO323696B1 (no)	1997-01-28	1999-07-27	Anvendelse av sentrale cannabinoid-reseptor-antagonister for regulering av appetitt

Country Status (31)

Country	Link
US (3)	US6344474B1 (sr)
EP (2)	EP0969835B1 (sr)
JP (1)	JP3676383B2 (sr)
AR (1)	AR011776A1 (sr)
AT (1)	ATE358480T1 (sr)
AU (1)	AU6219398A (sr)
BR (1)	BR9806801A (sr)
CA (1)	CA2278661A1 (sr)
DE (1)	DE69837473T2 (sr)
DK (1)	DK0969835T3 (sr)
DZ (1)	DZ2405A1 (sr)
EE (1)	EE04630B1 (sr)
ES (1)	ES2285760T3 (sr)
FR (1)	FR2758723B1 (sr)
GT (1)	GT199800021A (sr)
HR (1)	HRP980042A2 (sr)
ID (1)	ID22216A (sr)
IS (1)	IS5113A (sr)
LV (1)	LV12354B (sr)
ME (1)	MEP26508A (sr)
MY (1)	MY117251A (sr)
NO (1)	NO323696B1 (sr)
PT (1)	PT969835E (sr)
RS (1)	RS49830B (sr)
SA (1)	SA98181113B1 (sr)
SK (1)	SK99799A3 (sr)
TR (1)	TR199901721T2 (sr)
TW (1)	TW450808B (sr)
UY (1)	UY24847A1 (sr)
WO (1)	WO1998032441A1 (sr)
ZA (1)	ZA98691B (sr)

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1997
- 1997-01-28 FR FR9700870A patent/FR2758723B1/fr not_active Expired - Fee Related
1998
- 1998-01-20 UY UY24847A patent/UY24847A1/es not_active Application Discontinuation
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- 1998-01-28 WO PCT/FR1998/000154 patent/WO1998032441A1/fr not_active Ceased
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- 1998-01-28 EP EP98904238A patent/EP0969835B1/fr not_active Expired - Lifetime
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- 1998-04-21 SA SA98181113A patent/SA98181113B1/ar unknown
1999
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2002
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Also Published As

Publication number	Publication date
MY117251A (en)	2004-06-30
HRP980042A2 (en)	1998-10-31
AR011776A1 (es)	2000-09-13
EE04630B1 (et)	2006-06-15
NO993634D0 (no)	1999-07-27
HK1022829A1 (en)	2000-08-25
ATE358480T1 (de)	2007-04-15
MEP26508A (en)	2010-06-10
BR9806801A (pt)	2000-05-16
US20020128302A1 (en)	2002-09-12
AU6219398A (en)	1998-08-18
WO1998032441A1 (fr)	1998-07-30
SK99799A3 (en)	2000-06-12
EP0969835B1 (fr)	2007-04-04
EP1795194A2 (fr)	2007-06-13
GT199800021A (es)	1999-07-22
FR2758723B1 (fr)	1999-04-23
UY24847A1 (es)	1998-04-21
LV12354A (lv)	1999-10-20
FR2758723A1 (fr)	1998-07-31
RS49830B (sr)	2008-08-07
DZ2405A1 (fr)	2003-01-04
DE69837473D1 (de)	2007-05-16
ES2285760T3 (es)	2007-11-16
SA98181113B1 (ar)	2006-06-25
JP3676383B2 (ja)	2005-07-27
TW450808B (en)	2001-08-21
IS5113A (is)	1999-07-12
EP1795194A3 (fr)	2008-04-30
ZA98691B (en)	1998-08-05
JP2001501971A (ja)	2001-02-13
PT969835E (pt)	2007-07-12
US6344474B1 (en)	2002-02-05
LV12354B (en)	2000-02-20
NO993634L (no)	1999-09-27
DE69837473T2 (de)	2007-12-13
DK0969835T3 (da)	2007-08-06
EE9900304A (et)	2000-02-15
YU35099A (sh)	2002-08-12
EP0969835A1 (fr)	2000-01-12
CA2278661A1 (en)	1998-07-30
US20050026986A1 (en)	2005-02-03
TR199901721T2 (xx)	1999-10-21
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HK1022829B (en)	2007-09-14	Use of central cannabinoid receptor antagonists for regulating appetency
MXPA99006785A (en)	2000-07-01	Use of central cannabinoid receptor antagonists for regulating appetence
HK1102368A (en)	2007-11-16	Use of an antagonist of cb1 receivers associated with a beta3-agonist for preparing medication to be used for treating appetence
CA2451798C (en)	2010-11-02	Use of d4 and 5-ht2a antagonists, inverse agonists or partial agonists
HK1128229A (en)	2009-10-23	Pharmaceutical compositions comprising cbx cannabinoid receptor modulators and potassium channel modulators