NO323761B1 - Fremgangsmate for fremstilling av en poros matrise av legemiddel samt farmasoytisk preparat omfattende denne. - Google Patents

Fremgangsmate for fremstilling av en poros matrise av legemiddel samt farmasoytisk preparat omfattende denne. Download PDF

Info

Publication number: NO323761B1
Authority: NO; Norway
Prior art keywords: drug; solution; matrix; forming agent; hydrochloride
Prior art date: 1999-05-27

Application number

NO20015753A

Other languages

English (en)

Norwegian (no)

Other versions

NO20015753D0 (no

NO20015753L (no

Inventor

Julie Ann Straub

Greg Randall

Iii Donald E Chickering

Sarwat Khatak

Howard Bernstein

Original Assignee

Acusphere Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-27

Filing date

2001-11-26

Publication date

2007-07-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27495210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO323761(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-11-04 Priority claimed from US09/433,486 external-priority patent/US6395300B1/en

2001-11-26 Application filed by Acusphere Inc filed Critical Acusphere Inc

2001-11-26 Publication of NO20015753D0 publication Critical patent/NO20015753D0/no

2002-01-28 Publication of NO20015753L publication Critical patent/NO20015753L/no

2007-07-02 Publication of NO323761B1 publication Critical patent/NO323761B1/no

Links

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LCTORFDMHNKUSG-XTTLPDOESA-N vancomycin monohydrochloride Chemical compound Cl.O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 LCTORFDMHNKUSG-XTTLPDOESA-N 0.000 description 1
229960003048 vinblastine Drugs 0.000 description 1
JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
229960004528 vincristine Drugs 0.000 description 1
OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000019155 vitamin A Nutrition 0.000 description 1
239000011719 vitamin A Substances 0.000 description 1
235000019166 vitamin D Nutrition 0.000 description 1
239000011710 vitamin D Substances 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
235000019168 vitamin K Nutrition 0.000 description 1
239000011712 vitamin K Substances 0.000 description 1
229960002647 warfarin sodium Drugs 0.000 description 1
238000005303 weighing Methods 0.000 description 1
238000001238 wet grinding Methods 0.000 description 1
239000000811 xylitol Substances 0.000 description 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
229960002675 xylitol Drugs 0.000 description 1
FYGDTMLNYKFZSV-BYLHFPJWSA-N β-1,4-galactotrioside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-BYLHFPJWSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Materials For Medical Uses (AREA)
Epoxy Compounds (AREA)

NO20015753A 1999-05-27 2001-11-26 Fremgangsmate for fremstilling av en poros matrise av legemiddel samt farmasoytisk preparat omfattende denne. NO323761B1 (no)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US13632399P	1999-05-27	1999-05-27
US15865999P	1999-10-08	1999-10-08
US09/433,486 US6395300B1 (en)	1999-05-27	1999-11-04	Porous drug matrices and methods of manufacture thereof
US18631000P	2000-03-02	2000-03-02
PCT/US2000/014578 WO2000072827A2 (en)	1999-05-27	2000-05-25	Porous drug matrices and methods of manufacture thereof

Publications (3)

Publication Number	Publication Date
NO20015753D0 NO20015753D0 (no)	2001-11-26
NO20015753L NO20015753L (no)	2002-01-28
NO323761B1 true NO323761B1 (no)	2007-07-02

Family

ID=27495210

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20015753A NO323761B1 (no)	1999-05-27	2001-11-26	Fremgangsmate for fremstilling av en poros matrise av legemiddel samt farmasoytisk preparat omfattende denne.

Country Status (18)

Country	Link
EP (1)	EP1180020B2 (de)
JP (1)	JP4722295B2 (de)
KR (2)	KR100883477B1 (de)
CN (1)	CN1240373C (de)
AT (1)	ATE312601T1 (de)
AU (1)	AU768022B2 (de)
BR (1)	BR0010984A (de)
CA (1)	CA2371836C (de)
DE (1)	DE60024811T3 (de)
DK (1)	DK1180020T4 (de)
ES (1)	ES2250141T5 (de)
HK (1)	HK1048956B (de)
IL (2)	IL146659A0 (de)
MX (1)	MXPA01012106A (de)
NO (1)	NO323761B1 (de)
NZ (1)	NZ516083A (de)
TW (1)	TWI274589B (de)
WO (1)	WO2000072827A2 (de)

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AU756693B2 (en) *	1997-09-29	2003-01-23	Novartis Ag	Stabilized bioactive preparations and methods of use
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2000
- 2000-05-25 NZ NZ516083A patent/NZ516083A/en not_active IP Right Cessation
- 2000-05-25 DK DK00939365T patent/DK1180020T4/da active
- 2000-05-25 HK HK03101310.8A patent/HK1048956B/zh not_active IP Right Cessation
- 2000-05-25 CN CNB008081611A patent/CN1240373C/zh not_active Expired - Fee Related
- 2000-05-25 WO PCT/US2000/014578 patent/WO2000072827A2/en not_active Ceased
- 2000-05-25 BR BR0010984-3A patent/BR0010984A/pt not_active IP Right Cessation
- 2000-05-25 DE DE60024811T patent/DE60024811T3/de not_active Expired - Lifetime
- 2000-05-25 KR KR1020077012286A patent/KR100883477B1/ko not_active Expired - Fee Related
- 2000-05-25 ES ES00939365T patent/ES2250141T5/es not_active Expired - Lifetime
- 2000-05-25 AU AU54459/00A patent/AU768022B2/en not_active Ceased
- 2000-05-25 IL IL14665900A patent/IL146659A0/xx unknown
- 2000-05-25 KR KR1020017015052A patent/KR100752000B1/ko not_active Expired - Fee Related
- 2000-05-25 CA CA002371836A patent/CA2371836C/en not_active Expired - Fee Related
- 2000-05-25 JP JP2000620939A patent/JP4722295B2/ja not_active Expired - Fee Related
- 2000-05-25 AT AT00939365T patent/ATE312601T1/de active
- 2000-05-25 EP EP00939365A patent/EP1180020B2/de not_active Expired - Lifetime
- 2000-05-25 MX MXPA01012106A patent/MXPA01012106A/es active IP Right Grant
- 2000-05-29 TW TW089110363A patent/TWI274589B/zh not_active IP Right Cessation
2001
- 2001-11-21 IL IL146659A patent/IL146659A/en not_active IP Right Cessation
- 2001-11-26 NO NO20015753A patent/NO323761B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1048956B (zh)	2006-07-28
JP2003500438A (ja)	2003-01-07
CA2371836A1 (en)	2000-12-07
DE60024811D1 (de)	2006-01-19
KR100752000B1 (ko)	2007-08-28
AU768022B2 (en)	2003-11-27
KR100883477B1 (ko)	2009-02-16
CA2371836C (en)	2006-01-31
ES2250141T3 (es)	2006-04-16
KR20020011992A (ko)	2002-02-09
EP1180020B1 (de)	2005-12-14
DK1180020T4 (da)	2009-10-05
CN1365274A (zh)	2002-08-21
HK1094775A1 (zh)	2007-04-13
NO20015753D0 (no)	2001-11-26
DE60024811T2 (de)	2006-09-14
WO2000072827A2 (en)	2000-12-07
ES2250141T5 (es)	2009-11-05
NZ516083A (en)	2003-08-29
BR0010984A (pt)	2002-04-30
HK1048956A1 (en)	2003-04-25
EP1180020A2 (de)	2002-02-20
IL146659A0 (en)	2002-07-25
JP4722295B2 (ja)	2011-07-13
WO2000072827A3 (en)	2001-01-25
AU5445900A (en)	2000-12-18
MXPA01012106A (es)	2003-06-30
TWI274589B (en)	2007-03-01
CN1240373C (zh)	2006-02-08
EP1180020B2 (de)	2009-06-24
KR20070069219A (ko)	2007-07-02
DE60024811T3 (de)	2010-01-07
IL146659A (en)	2010-05-31
NO20015753L (no)	2002-01-28
WO2000072827A9 (en)	2002-01-31
DK1180020T3 (da)	2006-03-27
ATE312601T1 (de)	2005-12-15

Legal Events

Date	Code	Title	Description
2016-12-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
EP1180020B2 (de)	2009-06-24	Poröse arzneistoffmatrizen und deren herstellungsverfahren
US6932983B1 (en)	2005-08-23	Porous drug matrices and methods of manufacture thereof
US7919119B2 (en)	2011-04-05	Porous drug matrices and methods of manufacture thereof
EP1973527B1 (de)	2009-10-07	Verfahren zur herstellung von pharmazeutischen formulierungen auf teilchenbasis zur parenteralen verabreichung
US20070264343A1 (en)	2007-11-15	Methods for making and using particulate pharmaceutical formulations for sustained release
US20100151036A1 (en)	2010-06-17	Multiphase drug delivery system
EP1642572A1 (de)	2006-04-05	Poröse Matrices für Arzneistoffe und deren Herstellungsverfahren
ZA200110347B (en)	2003-07-30	Porous drug matrices and methods of manufacture thereof.
HK1094775B (en)	2008-08-22	Porous drug matrices and methods of manufacture thereof