NO782403L - Fremgangsmaate for fremstilling av benzylidenderivarter - Google Patents

Fremgangsmaate for fremstilling av benzylidenderivarter

Info

Publication number: NO782403L
Authority: NO; Norway
Prior art keywords: alkyl; benzyl; radical; formula; procedure
Prior art date: 1977-07-12

Application number

NO782403A

Other languages

English (en)

Norwegian (no)

Inventor

Jean-Pierre Kaplan

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-07-12

Filing date

1978-07-10

Publication date

1979-01-15

1978-07-10 Application filed by Synthelabo filed Critical Synthelabo

1979-01-15 Publication of NO782403L publication Critical patent/NO782403L/no

Links

238000000034 method Methods 0.000 title claims description 10
238000002360 preparation method Methods 0.000 title claims description 3
-1 BENZYLIDENE Chemical class 0.000 title 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 18
239000002253 acid Substances 0.000 claims description 5
SDGHXWKVBZYHRR-UHFFFAOYSA-N 2-(1h-imidazol-2-ylsulfonyl)-1h-imidazole Chemical compound N=1C=CNC=1S(=O)(=O)C1=NC=CN1 SDGHXWKVBZYHRR-UHFFFAOYSA-N 0.000 claims description 4
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 4
150000001412 amines Chemical class 0.000 claims description 4
125000004432 carbon atom Chemical group C* 0.000 claims description 4
125000005843 halogen group Chemical group 0.000 claims description 3
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 claims description 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 2
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 2
125000000217 alkyl group Chemical group 0.000 claims description 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims description 2
229910052801 chlorine Inorganic materials 0.000 claims description 2
239000000460 chlorine Substances 0.000 claims description 2
125000000753 cycloalkyl group Chemical group 0.000 claims description 2
229910052731 fluorine Inorganic materials 0.000 claims description 2
239000011737 fluorine Substances 0.000 claims description 2
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
150000003254 radicals Chemical class 0.000 claims description 2
239000002904 solvent Substances 0.000 claims description 2
125000001424 substituent group Chemical group 0.000 claims description 2
229910021529 ammonia Inorganic materials 0.000 claims 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 claims 1
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 22
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 6
239000003208 petroleum Substances 0.000 description 5
239000003610 charcoal Substances 0.000 description 4
239000000203 mixture Substances 0.000 description 4
238000003756 stirring Methods 0.000 description 4
150000001408 amides Chemical class 0.000 description 3
150000001875 compounds Chemical class 0.000 description 3
239000011521 glass Substances 0.000 description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 description 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
DNSISZSEWVHGLH-UHFFFAOYSA-N butanamide Chemical compound CCCC(N)=O DNSISZSEWVHGLH-UHFFFAOYSA-N 0.000 description 2
PFKFTWBEEFSNDU-UHFFFAOYSA-N carbonyldiimidazole Chemical compound C1=CN=CN1C(=O)N1C=CN=C1 PFKFTWBEEFSNDU-UHFFFAOYSA-N 0.000 description 2
230000008020 evaporation Effects 0.000 description 2
238000001704 evaporation Methods 0.000 description 2
239000005457 ice water Substances 0.000 description 2
230000008018 melting Effects 0.000 description 2
238000002844 melting Methods 0.000 description 2
239000002244 precipitate Substances 0.000 description 2
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 2
239000005711 Benzoic acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
229940125681 anticonvulsant agent Drugs 0.000 description 1
239000001961 anticonvulsive agent Substances 0.000 description 1
125000004429 atom Chemical group 0.000 description 1
235000010233 benzoic acid Nutrition 0.000 description 1
JYYOBHFYCIDXHH-UHFFFAOYSA-N carbonic acid;hydrate Chemical compound O.OC(O)=O JYYOBHFYCIDXHH-UHFFFAOYSA-N 0.000 description 1
238000001035 drying Methods 0.000 description 1
239000000706 filtrate Substances 0.000 description 1
125000001153 fluoro group Chemical group F* 0.000 description 1
239000002198 insoluble material Substances 0.000 description 1
150000002576 ketones Chemical class 0.000 description 1
229910052943 magnesium sulfate Inorganic materials 0.000 description 1
235000019341 magnesium sulphate Nutrition 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
AFDMODCXODAXLC-UHFFFAOYSA-N phenylmethanimine Chemical class N=CC1=CC=CC=C1 AFDMODCXODAXLC-UHFFFAOYSA-N 0.000 description 1
239000000047 product Substances 0.000 description 1
239000007787 solid Substances 0.000 description 1
230000003595 spectral effect Effects 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Detergent Compositions (AREA)

NO782403A 1977-07-12 1978-07-10 Fremgangsmaate for fremstilling av benzylidenderivarter NO782403L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7721445A FR2397397A2 (fr)	1977-07-12	1977-07-12	Preparation de derives benzylideniques

Publications (1)

Publication Number	Publication Date
NO782403L true NO782403L (no)	1979-01-15

Family

ID=9193280

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO782403A NO782403L (no)	1977-07-12	1978-07-10	Fremgangsmaate for fremstilling av benzylidenderivarter

Country Status (16)

Country	Link
JP (1)	JPS5419953A (it)
AT (1)	ATA501078A (it)
AU (1)	AU3794678A (it)
BE (1)	BE868949R (it)
DE (1)	DE2830034A1 (it)
DK (1)	DK310878A (it)
ES (1)	ES471606A2 (it)
FR (1)	FR2397397A2 (it)
GB (1)	GB2001066A (it)
IL (1)	IL55103A0 (it)
IT (1)	IT1108730B (it)
LU (1)	LU79946A1 (it)
NL (1)	NL7807354A (it)
NO (1)	NO782403L (it)
SE (1)	SE7807729L (it)
ZA (1)	ZA783940B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH662664A5 (de) *	1983-07-01	1987-10-15	Loepfe Ag Geb	Regelverfahren und regeleinrichtung fuer eine vorrichtung oder vorrichtungsgruppe und vorrichtung mit einer regeleinrichtung.

1977
- 1977-07-12 FR FR7721445A patent/FR2397397A2/fr active Granted
1978
- 1978-07-07 NL NL7807354A patent/NL7807354A/xx not_active Application Discontinuation
- 1978-07-07 DE DE19782830034 patent/DE2830034A1/de not_active Withdrawn
- 1978-07-07 IL IL55103A patent/IL55103A0/xx unknown
- 1978-07-10 NO NO782403A patent/NO782403L/no unknown
- 1978-07-10 LU LU79946A patent/LU79946A1/xx unknown
- 1978-07-10 ZA ZA00783940A patent/ZA783940B/xx unknown
- 1978-07-10 IT IT25496/78A patent/IT1108730B/it active
- 1978-07-11 JP JP8501678A patent/JPS5419953A/ja active Pending
- 1978-07-11 SE SE7807729A patent/SE7807729L/xx unknown
- 1978-07-11 DK DK783108A patent/DK310878A/da unknown
- 1978-07-11 AU AU37946/78A patent/AU3794678A/en active Pending
- 1978-07-11 AT AT501078A patent/ATA501078A/de not_active Application Discontinuation
- 1978-07-11 ES ES471606A patent/ES471606A2/es not_active Expired
- 1978-07-11 GB GB7829520A patent/GB2001066A/en not_active Withdrawn
- 1978-07-12 BE BE189243A patent/BE868949R/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES471606A2 (es)	1979-02-16
ATA501078A (de)	1980-02-15
ZA783940B (en)	1979-07-25
IT7825496A0 (it)	1978-07-10
SE7807729L (sv)	1979-01-13
GB2001066A (en)	1979-01-24
LU79946A1 (it)	1978-12-12
FR2397397A2 (fr)	1979-02-09
DK310878A (da)	1979-01-13
AU3794678A (en)	1980-01-17
BE868949R (fr)	1979-01-12
JPS5419953A (en)	1979-02-15
IT1108730B (it)	1985-12-09
FR2397397B2 (it)	1982-09-17
DE2830034A1 (de)	1979-02-01
IL55103A0 (en)	1978-09-29
NL7807354A (nl)	1979-01-16

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