NO812720L - Fremgangsmaate for fremstilling av heteroprostaglandinderivater - Google Patents

Fremgangsmaate for fremstilling av heteroprostaglandinderivater

Info

Publication number
NO812720L
NO812720L NO812720A NO812720A NO812720L NO 812720 L NO812720 L NO 812720L NO 812720 A NO812720 A NO 812720A NO 812720 A NO812720 A NO 812720A NO 812720 L NO812720 L NO 812720L
Authority
NO
Norway
Prior art keywords
hydroxy
acid
compound
benzyloxy
compounds
Prior art date
Application number
NO812720A
Other languages
English (en)
Norwegian (no)
Inventor
Stephan Gero
Jeanine Cleophax
Jean-Claude Barriere
Andre Cier
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO812720L publication Critical patent/NO812720L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/18—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C43/196—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/60—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/38—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/47—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
NO812720A 1980-08-12 1981-08-11 Fremgangsmaate for fremstilling av heteroprostaglandinderivater NO812720L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8026240 1980-08-12
GB8113487 1981-05-01

Publications (1)

Publication Number Publication Date
NO812720L true NO812720L (no) 1982-02-15

Family

ID=26276527

Family Applications (1)

Application Number Title Priority Date Filing Date
NO812720A NO812720L (no) 1980-08-12 1981-08-11 Fremgangsmaate for fremstilling av heteroprostaglandinderivater

Country Status (27)

Country Link
US (1) US4377704A (fr)
AU (2) AU542975B2 (fr)
BG (1) BG36345A3 (fr)
CH (2) CH655716A5 (fr)
DD (3) DD213437A5 (fr)
DE (1) DE3131616A1 (fr)
DK (1) DK356481A (fr)
ES (2) ES504681A0 (fr)
FI (1) FI812468A7 (fr)
FR (2) FR2488604A1 (fr)
GR (1) GR74314B (fr)
HU (1) HU191416B (fr)
IL (1) IL63369A (fr)
IS (1) IS1184B6 (fr)
IT (1) IT1214436B (fr)
LU (1) LU83547A1 (fr)
NL (1) NL8103710A (fr)
NO (1) NO812720L (fr)
NZ (1) NZ197729A (fr)
OA (1) OA06879A (fr)
PL (2) PL137212B1 (fr)
PT (1) PT73457B (fr)
RO (2) RO82680B (fr)
SE (2) SE442297B (fr)
SU (1) SU1187716A3 (fr)
YU (2) YU193781A (fr)
ZW (1) ZW17881A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8510277D0 (en) * 1985-04-23 1985-05-30 Glaxo Group Ltd Carbocyclic compounds
AU635065B2 (en) * 1989-09-08 1993-03-11 Emmanouilidis, Theo Mountable washing device
US6711436B1 (en) 1997-08-08 2004-03-23 Duke University Compositions, apparatus and methods for facilitating surgical procedures
AU758370B2 (en) * 1997-08-08 2003-03-20 Duke University Compositions, apparatus and methods for facilitating surgical procedures

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3664502A (en) * 1970-06-26 1972-05-23 Bird Machine Co Slurry screen and process of making it
US4229592A (en) * 1978-02-06 1980-10-21 Kansas University Endowment Association Intermediate for prostaglandins and process for preparing the intermediate
SE7906017L (sv) * 1978-07-11 1980-02-13 Glaxo Group Ltd Prostanoida foreningar

Also Published As

Publication number Publication date
SE442297B (sv) 1985-12-16
US4377704A (en) 1983-03-22
DE3131616A1 (de) 1982-04-22
AU3406784A (en) 1985-01-31
FR2509306A1 (fr) 1983-01-14
SE8502007D0 (sv) 1985-04-25
IS1184B6 (is) 1985-05-13
IT1214436B (it) 1990-01-18
FI812468L (fi) 1982-02-13
PL133879B1 (en) 1985-07-31
FI812468A7 (fi) 1982-02-13
HU191416B (en) 1987-02-27
SE8104703L (sv) 1982-02-13
CH650251A5 (fr) 1985-07-15
IL63369A (en) 1985-11-29
ZW17881A1 (en) 1981-10-14
AU542975B2 (en) 1985-03-28
DD202428A5 (de) 1983-09-14
YU86183A (en) 1984-04-30
RO82680B (ro) 1984-06-30
FR2488604B1 (fr) 1984-11-09
SU1187716A3 (ru) 1985-10-23
DD223712A5 (de) 1985-06-19
PL137212B1 (en) 1986-05-31
IT8123455A0 (it) 1981-08-10
ES8305710A1 (es) 1983-04-16
SE8502007L (sv) 1985-04-25
PT73457A (en) 1981-08-01
ES514592A0 (es) 1983-04-16
PT73457B (en) 1982-10-15
AU7400781A (en) 1982-03-04
ES8301465A1 (es) 1982-12-01
FR2488604A1 (fr) 1982-02-19
DK356481A (da) 1982-02-13
GR74314B (fr) 1984-06-22
IS2661A7 (is) 1982-02-13
NL8103710A (nl) 1982-03-01
DD213437A5 (de) 1984-09-12
OA06879A (fr) 1983-02-28
FR2509306B1 (fr) 1984-04-13
IL63369A0 (en) 1981-10-30
YU193781A (en) 1984-02-29
ES504681A0 (es) 1982-12-01
BG36345A3 (bg) 1984-10-15
NZ197729A (en) 1985-03-20
RO82680A (fr) 1984-05-12
HUT34147A (en) 1985-02-28
RO87011A (fr) 1985-05-20
LU83547A1 (fr) 1981-12-01
PL232567A1 (en) 1983-01-03
CH655716A5 (fr) 1986-05-15

Similar Documents

Publication Publication Date Title
KR880002298B1 (ko) 술포네이트 유도체의 제조법
Aristoff et al. Total synthesis of a novel antiulcer agent via a modification of the intramolecular Wadsworth-Emmons-Wittig reaction
US7057076B2 (en) Bicyclic and tricyclic cannabinoids
US5459160A (en) Iridoid derivatives and the use thereof as a drug
NO833871L (no) Fremgangsmaate for fremstilling av prostaglandinanaloger med 7-oksabicykloheptan og substituert amino
Wipf et al. Synthesis and biological evaluation of deoxypreussomerin A and palmarumycin CP1 and related naphthoquinone spiroketals
FR2553774A1 (fr) Analogues interphenylene de prostaglandines a substitution 7-oxabicycloheptane, utiles notamment comme agents cardiovasculaires
Grieco et al. Synthesis of mono-and bifunctional. alpha.-methylene lactone systems as potential tumor inhibitors
BE1003843A4 (fr) Procede stereospecifique pour la preparation des enantiomeres de la furo (3,4-c) pyridine et composes ainsi obtenus.
GB1574246A (en) Prostaglandin derivatives and process for preparing the same
US7910752B2 (en) Anticancer compound, intermediate therefor, and processes for producing these
DeBoer et al. Baeyer-Villiger oxidation of. DELTA. 1, 9-octalone-2 and. DELTA. 1, 8-indanone-2
US4377704A (en) Hetero-prostaglandin derivatives and processes for preparing them
JPS60174753A (ja) ノルボルナン‐及びノルボルネン‐カルボン酸アミド、その製法及びその用途
US4292432A (en) Novel aldol derivatives and production thereof
IE41850B1 (en) Benzofuran derivatives and a process for the manufacture thereof
Cantrell Reactivity of photochemically excited 3-acylthiophenes, 3-acylfurans, and the formylthiophenes and furans
GB2082176A (en) Heteroprostaglandin derivatives and processes for preparing them
CA1194021A (fr) Heteroprostaglandines derivees et procede de preparation
RU2036913C1 (ru) Способ получения производных бензоксазолона
HU185645B (en) Process for the production of 11-hydroxy-13-oxa-prostaglandine-derivatives
US3799967A (en) Synthetic prostaglandins
BE884145R (fr) Composes indoliques nouveaux
US4176196A (en) Hypoglycemic arylcyclohexane acetic acids
CA1180339A (fr) Composes pour la preparation de derives hetero des prostaglandines