NO820090L - Fremgangsmaate for fremstilling og behandling av renninderivater - Google Patents

Fremgangsmaate for fremstilling og behandling av renninderivater

Info

Publication number
NO820090L
NO820090L NO820090A NO820090A NO820090L NO 820090 L NO820090 L NO 820090L NO 820090 A NO820090 A NO 820090A NO 820090 A NO820090 A NO 820090A NO 820090 L NO820090 L NO 820090L
Authority
NO
Norway
Prior art keywords
prorennin
derivatives
cleaning
procedure
preparation
Prior art date
Application number
NO820090A
Other languages
English (en)
Norwegian (no)
Inventor
Bernadette Lavetsky Alford
Jen-I Mao
Donald Taylor Moir
Alison Taunton-Rigby
Gerald Francis Vovis
Original Assignee
Collaborative Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26919852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO820090(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Collaborative Res Inc filed Critical Collaborative Res Inc
Publication of NO820090L publication Critical patent/NO820090L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C12N1/185—Saccharomyces isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/865—Saccharomyces cerevisiae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO820090A 1981-01-16 1982-01-13 Fremgangsmaate for fremstilling og behandling av renninderivater NO820090L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22571781A 1981-01-16 1981-01-16
US06/325,481 US4666847A (en) 1981-01-16 1981-12-01 Recombinant DNA means and method

Publications (1)

Publication Number Publication Date
NO820090L true NO820090L (no) 1982-07-19

Family

ID=26919852

Family Applications (1)

Application Number Title Priority Date Filing Date
NO820090A NO820090L (no) 1981-01-16 1982-01-13 Fremgangsmaate for fremstilling og behandling av renninderivater

Country Status (15)

Country Link
US (1) US4666847A (da)
EP (1) EP0057350B1 (da)
JP (2) JPH0716419B2 (da)
AT (1) ATE172493T1 (da)
AU (1) AU560340B2 (da)
BR (1) BR8200191A (da)
CA (1) CA1341300C (da)
DE (1) DE3280479T2 (da)
DK (1) DK15182A (da)
ES (2) ES8401132A1 (da)
FI (1) FI84080C (da)
GB (1) GB2091271B (da)
IE (1) IE52760B1 (da)
NO (1) NO820090L (da)
NZ (1) NZ199445A (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525484A (en) * 1981-01-16 1996-06-11 Genome Therapeutics Corp. Recombinant DNA means and method for producing rennin, prorenin and pre-prorennin
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
IE53517B1 (en) * 1981-06-17 1988-12-07 Celltech Ltd Process for the production of a polypeptide
JPS5832896A (ja) * 1981-08-24 1983-02-25 Teruhiko Beppu 複合プラスミド及びそれを含有する微生物
US4615974A (en) * 1981-08-25 1986-10-07 Celltech Limited Yeast expression vectors
BR8205954A (pt) * 1981-10-14 1983-09-13 Unilever Nv Sequencia de dna,plasmidio recombinante,cultura bacteriana e microorganismos
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
JPS59501572A (ja) * 1982-05-19 1984-09-06 ユニリーバー　ナームローゼ　ベンノートシヤープ クルイベロミセス属酵母およびその製造法
IL68797A0 (en) * 1982-07-01 1983-09-30 Genex Corp Cloned bovine calf chymosin and calf prochymosin genes,their preparation,plasmids containing them and microorganisms transformed by those plasmids
IE56372B1 (en) * 1982-12-22 1991-07-03 Genentech Inc Microbially produced rennet methods for its production and plasmids used for its production
US4961938A (en) * 1982-12-22 1990-10-09 Genentech, Inc. Preparation of cheese with rennin from recombinant microbial cells
US4935369A (en) * 1982-12-22 1990-06-19 Genentech, Inc. Isolation of active microbially produced bovine rennin
US4661454A (en) * 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
JPS59166086A (ja) * 1983-03-09 1984-09-19 Teruhiko Beppu 新規な発現型プラスミドとそれらを用いて仔牛プロキモシン遺伝子を大腸菌内で発現させる方法
DE3480006D1 (en) * 1983-05-19 1989-11-09 Unilever Nv Improvements in the expression of newly introduced genes in yeast cells
EP0128743A3 (en) * 1983-06-07 1985-12-27 Genex Corporation Expression of foreign genes in yeast
AU3036684A (en) * 1983-07-07 1985-01-10 Genex Corp. Production of bovine calf chymosin
US4935354A (en) * 1983-07-14 1990-06-19 Genentech, Inc. Rennin from recombinant microbial cells for preparation of cheese
US4721673A (en) * 1983-09-01 1988-01-26 Genex Corporation Recovery and activation process for microbially produced calf prochymosin
US5639639A (en) * 1983-11-02 1997-06-17 Genzyme Corporation Recombinant heterodimeric human fertility hormones, and methods, cells, vectors and DNA for the production thereof
US4935370A (en) * 1983-12-23 1990-06-19 Pfizer Inc. Expression plasmids for improved production of heterologous protein in bacteria
NL8400687A (nl) * 1984-03-02 1985-10-01 Unilever Nv Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit.
JPS60188093A (ja) * 1984-03-09 1985-09-25 Teruhiko Beppu 枯草菌に於ける形質発現プラスミド
JPS60188077A (ja) * 1984-03-09 1985-09-25 Teruhiko Beppu 仔牛プロキモシンｃＤΝＡの全配列を有する新規な発現プラスミド
ATE71147T1 (de) * 1984-05-11 1992-01-15 Berlex Lab Verfahren zur herstellung eines im wesentlichen nichtloeslichen polypetids unter verwendung nichtionischer detergentien.
US5082775A (en) * 1984-05-11 1992-01-21 Berlex Laboratories, Inc. Efficient process for isolating insoluble heterologous protein using non-ionic detergents
GB2178431B (en) * 1985-07-15 1989-11-22 Bioteknika International Genetically engineered yeast strains
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US6004785A (en) 1985-08-29 1999-12-21 Genencor International Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
US4937189A (en) * 1985-10-18 1990-06-26 Pfizer Inc. Expression and secretion of heterologous proteins by Yarrowia lipolytica transformants
US5536661A (en) * 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
US5766912A (en) 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
JPH0673456B2 (ja) * 1986-04-26 1994-09-21 三共株式会社 ヒト・膵臓エラスタ−ゼ▲ｉ▼
DE3781217T2 (de) * 1986-07-22 1992-12-17 Ciba Geigy Ag Herstellung von verwandten polypeptiden des bindungsfaktors.
GB2200118A (en) * 1987-01-23 1988-07-27 Allelix Inc Synthetic chymosin-and prochymosin-encoding DNA segments
US4977089A (en) * 1987-01-30 1990-12-11 Eli Lilly And Company Vector comprising signal peptide-encoding DNA for use in Bacillus and other microorganisms
US5162226A (en) 1987-08-24 1992-11-10 University Of Tennessee Research Corp. (U.T.R.C.) Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products
JPH02109984A (ja) * 1988-12-01 1990-04-23 Teruhiko Beppu 複合プラスミド及びそれを含有する微生物
US5139943A (en) * 1989-06-13 1992-08-18 Genencor International, Inc. Processes for the recovery of microbially produced chymosin
US5151358A (en) * 1989-06-13 1992-09-29 Genencor International, Inc. Processes for the recovery of naturally produced chymosin
JPH05505308A (ja) * 1990-03-13 1993-08-12 ハワイ・バイオテクノロジー・グループ・インコーポレイテツド アオパンカビ発現システム
AU9113991A (en) * 1990-11-19 1992-06-11 Biotechnology Research And Development Corporation Mutant orientable proteins and coated substrates
ES2171454T3 (es) * 1993-06-04 2002-09-16 Whitehead Biomedical Inst Proteinas de estres y sus usos.
US7157089B1 (en) * 1996-11-26 2007-01-02 Stressgen Biotechnologies Corporation Immune responses using compositions containing stress proteins
JP2003504074A (ja) * 1999-07-08 2003-02-04 ストレスゲン バイオテクノロジーズ コーポレイション インビトロでのＴｈ１様応答の誘導
US7390936B1 (en) * 1999-08-23 2008-06-24 Sembiosys Genetics Inc. Commercial production of chymosin in plants
US6964851B2 (en) * 1999-12-07 2005-11-15 Stressgen Biotechnologies Corp. Compositions and methods for detecting stress-inducible proteins
CA2396384A1 (en) * 2000-01-14 2001-07-19 Whitehead Institute For Biomedical Research In vivo ctl elicitation by heat shock protein fusion proteins maps to a discrete atp binding domain and is cd4+ t cell-independent
NZ523408A (en) * 2000-06-26 2006-02-24 Stressgen Biotechnologies Corp Human papilloma virus treatment
KR20030074787A (ko) * 2001-02-05 2003-09-19 스트레스젠 바이오테크놀러지스 코포레이션 Ｂ형 간염 바이러스 치료
EP1745068A4 (en) * 2004-03-30 2009-11-04 Sudershan Biotech Ltd RECOMBINANT CALM CHYMOSIN AND PROCESS FOR PRODUCING THE SAME

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136201A (en) * 1967-12-06 1979-01-23 Gb Fermentation Industries, Inc. Microbial rennin
FR2441659A1 (fr) * 1978-11-14 1980-06-13 Anvar Nouveaux plasmides hybrides et microorganismes les contenant
US4332892A (en) * 1979-01-15 1982-06-01 President And Fellows Of Harvard College Protein synthesis
DK159976C (da) * 1979-06-01 1991-05-27 Searle & Co Plasmidvektorer, fremgangsmaade til fremstilling deraf, bakterieceller transformeret med plasmidvektorer samt udtrykkelse af protein i transformerede bakterieceller
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
IE53517B1 (en) * 1981-06-17 1988-12-07 Celltech Ltd Process for the production of a polypeptide

Also Published As

Publication number Publication date
NZ199445A (en) 1985-07-12
DE3280479D1 (de) 1998-11-26
EP0057350A3 (en) 1982-12-01
FI820075L (fi) 1982-07-17
JPS57141287A (en) 1982-09-01
ATE172493T1 (de) 1998-11-15
ES508813A0 (es) 1983-12-01
US4666847A (en) 1987-05-19
JPH07108221B2 (ja) 1995-11-22
ES8700320A1 (es) 1986-10-01
ES524986A0 (es) 1986-10-01
DK15182A (da) 1982-07-17
BR8200191A (pt) 1982-11-09
FI84080B (fi) 1991-06-28
EP0057350A2 (en) 1982-08-11
CA1341300C (en) 2001-10-09
IE52760B1 (en) 1988-02-17
GB2091271B (en) 1984-08-30
IE820069L (en) 1983-06-01
ES8401132A1 (es) 1983-12-01
EP0057350B1 (en) 1998-10-21
GB2091271A (en) 1982-07-28
JPH0716419B2 (ja) 1995-03-01
DE3280479T2 (de) 1999-03-11
AU7945682A (en) 1982-07-22
FI84080C (fi) 1991-10-10
AU560340B2 (en) 1987-04-02
JPH07170978A (ja) 1995-07-11

Similar Documents

Publication Publication Date Title
NO820090L (no) Fremgangsmaate for fremstilling og behandling av renninderivater
EP0279582A3 (en) Dna sequences to target proteins to the mammary gland for efficient secretion
ES8700868A1 (es) Metodo de aislamiento de un fragmento de gen que codifica por lo menos una porcion de una proteina.
AU9058091A (en) Preparation of nucleic acid samples
PT76546B (en) Process for preparing functional human urokinase protein
ES2059367T3 (es) Produccion de proteinas mediante cultivo de celulas.
EP0232523A3 (en) Dna sequences which encode for proteins with the biological activity of husi-type i inhibitors, their production by gene technology and drugs containing these proteins
DE3382068D1 (de) Verfahren zum einbringen von klonierten amplifizierbaren genen in eukaryotische zellen und zur herstellung von proteinprodukten.
DK358787D0 (da) Vaekstfaktor, nucleotidsekvens kodende for vaekstfaktoren ekspressionsplasmid omfattende nucleotidsekvensen,vaert indeholdende plasmidet protein fremstillet af vaerten, fremgangsmaade til fremstilling af vaekstfaktoren og farmaceutisk praeparat indeholdendevaekstfaktoren
ATE2442T1 (de) Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung.
FR2227276A1 (en) Non-toxic nitrogen-active blood serum fractions - for culture of human diploid fibro-blasts, are prepd. by fractionation using ultrafiltration membrane sieves
DE69920216D1 (de) Biologisches material zur herstellung pharmazeutischer zusammensetzungen zur behandlung von säugetieren
ES8800723A1 (es) Un metodo para preparar renina humana.
ATE87977T1 (de) Herstellung menschlichen somatomedins c.
EP0396402A3 (en) Cell growth activators
ATE122097T1 (de) Expressionsvektor und verfahren zur regulierbaren herstellung von proteinen in eukaryonten.
JPS52148683A (en) Treatment of microbial cultivation liquid
SE8901715L (sv) En plasmid dna-konstruktion innehaallande dna-sekvenser
DK544789A (da) Transkaryot implantering
ATE59204T1 (de) Verfahren zum einbringen von klonierten amplifizierbaren genen in eukaryotische zellen und zur herstellung von proteinprodukten.
TH9321A (th) ผลิตภัณฑ์ปรากฎการณ์ใหม่สำหรับการรักษามะเร็ง