NO862193L - Antracyklinholdig preparater og fremgangsmaate for deres fremstilling. - Google Patents

Antracyklinholdig preparater og fremgangsmaate for deres fremstilling.

Info

Publication number: NO862193L
Authority: NO; Norway
Prior art keywords: anthracycle; procedures; preparation; containing preparations; vesicles
Prior art date: 1985-10-15

Application number

NO862193A

Other languages

English (en)

Other versions

NO862193D0 (no

NO172729B (no

NO172729C (no

Inventor

Eric Forssen

Original Assignee

Vestar Research Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-15

Filing date

1986-06-03

Publication date

1987-04-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25141806&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO862193(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-06-03 Application filed by Vestar Research Inc filed Critical Vestar Research Inc

1986-06-03 Publication of NO862193D0 publication Critical patent/NO862193D0/no

1987-04-21 Publication of NO862193L publication Critical patent/NO862193L/no

1993-05-24 Publication of NO172729B publication Critical patent/NO172729B/no

1993-09-01 Publication of NO172729C publication Critical patent/NO172729C/no

Links

238000002360 preparation method Methods 0.000 title 2
238000000034 method Methods 0.000 title 1
229940045799 anthracyclines and related substance Drugs 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
239000002245 particle Substances 0.000 abstract 2
HVVJCLFLKMGEIY-UHFFFAOYSA-N 2,3-dioctadecoxypropyl 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CCCCCCCCCCCCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)OCCCCCCCCCCCCCCCCCC HVVJCLFLKMGEIY-UHFFFAOYSA-N 0.000 abstract 1
STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 abstract 1
AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 abstract 1
229940034982 antineoplastic agent Drugs 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
229960000975 daunorubicin Drugs 0.000 abstract 1
STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
239000008121 dextrose Substances 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Dispersion Chemistry (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO862193A 1985-10-15 1986-06-03 Fremgangsmaate for fremstilling av en suspensjon av fosfolipidvesikler. NO172729C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US78753585A	1985-10-15	1985-10-15

Publications (4)

Publication Number	Publication Date
NO862193D0 NO862193D0 (no)	1986-06-03
NO862193L true NO862193L (no)	1987-04-21
NO172729B NO172729B (no)	1993-05-24
NO172729C NO172729C (no)	1993-09-01

Family

ID=25141806

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO862193A NO172729C (no)	1985-10-15	1986-06-03	Fremgangsmaate for fremstilling av en suspensjon av fosfolipidvesikler.

Country Status (10)

Country	Link
US (1)	US4769250A (no)
EP (1)	EP0219922B2 (no)
JP (1)	JPH0761947B2 (no)
KR (1)	KR890004689B1 (no)
AT (1)	ATE65392T1 (no)
AU (1)	AU587232B2 (no)
DE (1)	DE3680447D1 (no)
DK (1)	DK175201B1 (no)
IE (1)	IE58981B1 (no)
NO (1)	NO172729C (no)

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JP2501336B2 (ja) *	1987-07-02	1996-05-29	第一製薬株式会社	安定なリポソ−ム製剤
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JP3533215B2 (ja) *	1990-07-31	2004-05-31	ザリポソームカンパニー，インコーポレイテッド	アミノ酸及びペプチドのリポソーム内への蓄積
JP2599492B2 (ja) *	1990-08-21	1997-04-09	第一製薬株式会社	リポソーム製剤の製造法
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US5665381A (en) *	1992-02-25	1997-09-09	Nexstar Pharmaceuticals, Inc.	Inhibition of aggregation of drug containing particles
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DE69329792T2 (de) *	1992-10-08	2001-05-31	Supratek Pharma, Inc.	Zusammensetzung von in mizellen eingeschlossenen antineoplastischen wirkstoffen
US6093391A (en) *	1992-10-08	2000-07-25	Supratek Pharma, Inc.	Peptide copolymer compositions
US5817321A (en) *	1992-10-08	1998-10-06	Supratek Pharma, Inc.	Biological agent compositions
US5455044A (en) *	1993-05-14	1995-10-03	Depotech Corporation	Method for treating neurological disorders
JP3002702B2 (ja) *	1993-11-16	2000-01-24	スカイファームインコーポレーテッド	活性物質の制御放出を有する小胞
EP0664117A1 (de) *	1994-01-25	1995-07-26	F. Hoffmann-La Roche Ag	Liposomenlösungen
US5714163A (en) *	1994-06-27	1998-02-03	Nexstar Pharmaceuticals, Inc.	Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties
US5993850A (en) *	1994-09-13	1999-11-30	Skyepharma Inc.	Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
US20040208922A1 (en) *	1995-06-07	2004-10-21	The Regents Of The University Of California	Method for loading lipid like vesicles with drugs or other chemicals
US5931809A (en)	1995-07-14	1999-08-03	Depotech Corporation	Epidural administration of therapeutic compounds with sustained rate of release
WO1997042939A1 (en) *	1996-05-14	1997-11-20	Burzynski Research Inst	Liposomal antineoplaston therapies with markedly improved antineoplastic activity
US6060518A (en) *	1996-08-16	2000-05-09	Supratek Pharma Inc.	Polymer compositions for chemotherapy and methods of treatment using the same
DE19639811A1 (de) *	1996-09-27	1998-04-02	Artur Herzog Dr Mesmer	Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
US5997899A (en)	1996-10-01	1999-12-07	Skyepharma Inc.	Method for producing liposomes with increased percent of compound encapsulated
WO1999002139A1 (en) *	1997-07-10	1999-01-21	Keith Baker	Methods for universally distributing therapeutic agents to the brain
US6306432B1 (en)	1997-09-08	2001-10-23	Chiron Corporation	High and low load formulations of IGF-I in multivesicular liposomes
ES2343767T3 (es) *	1997-09-18	2010-08-09	Pacira Pharmaceuticals, Inc.	Composiciones anestesicas liposomicas de liberacion sostenida.
US6120800A (en) *	1997-09-25	2000-09-19	Nexstar Pharmaceuticals, Inc.	Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties
JP4575592B2 (ja) *	1997-11-14	2010-11-04	パシラファーマシューティカルズインコーポレーテッド	多小胞リポソームの製造
WO2000076525A1 (fr) *	1999-06-14	2000-12-21	Meiji Milk Products Co., Ltd.	Emulsions anticancereuses contenant des composes d'anthracycline
JP2005500293A (ja) *	2001-06-15	2005-01-06	コーナーストーンファーマシューティカルズ	標的とする組織及び細胞の治療に有用なナノ粒子を含む薬剤組成物及び診断のための組成物
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US20050118250A1 (en) *	2001-11-13	2005-06-02	Paul Tardi	Lipid carrier compositions with enhanced blood stability
US20030180348A1 (en) *	2002-03-22	2003-09-25	Levinson R. Saul	Transcellular drug delivery system
US8980310B2 (en) *	2002-12-31	2015-03-17	Bharat Serums and Vaccines, Ltd.	Non-pegylated long-circulating liposomes
GB2398495B (en) *	2003-01-23	2007-08-22	Kent G Lau	A drug delivery preparation comprising at least one anti-tumour drug and a topical carrier for the drug
US9149543B2 (en) *	2005-12-15	2015-10-06	The Trustees Of The University Of Pennsylvania	Methods and models for rapid, widespread delivery of genetic material to the CNS using non-viral, cationic lipid-mediated vectors
CA2706923A1 (en) *	2007-11-30	2009-06-11	Endo Pharmaceuticals Solutions, Inc.	Intravesical compositions with valrubicin for the treatment of bladder cancer
US11980636B2 (en)	2020-11-18	2024-05-14	Jazz Pharmaceuticals Ireland Limited	Treatment of hematological disorders
US11278494B1 (en)	2021-01-22	2022-03-22	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en)	2021-01-22	2021-06-15	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en)	2021-01-22	2024-11-26	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en)	2021-01-22	2022-06-14	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
GB2627096A (en)	2021-10-14	2024-08-14	Pacira Pharmaceuticals Inc	Bupivacaine multivesicular liposome formulations and uses thereof
US12246092B1 (en)	2024-05-20	2025-03-11	Pacira Pharmaceuticals, Inc.	Manufacturing of bupivacaine multivesicular liposomes
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1986
- 1986-02-27 IE IE53586A patent/IE58981B1/en not_active IP Right Cessation
- 1986-02-28 AU AU54184/86A patent/AU587232B2/en not_active Expired
- 1986-03-04 DK DK198600988A patent/DK175201B1/da not_active IP Right Cessation
- 1986-03-04 AT AT86301513T patent/ATE65392T1/de not_active IP Right Cessation
- 1986-03-04 DE DE8686301513T patent/DE3680447D1/de not_active Expired - Lifetime
- 1986-03-04 EP EP86301513A patent/EP0219922B2/en not_active Expired - Lifetime
- 1986-03-10 JP JP61052346A patent/JPH0761947B2/ja not_active Expired - Lifetime
- 1986-03-31 KR KR1019860002412A patent/KR890004689B1/ko not_active Expired
- 1986-06-03 NO NO862193A patent/NO172729C/no not_active IP Right Cessation
1987
- 1987-10-26 US US07/112,073 patent/US4769250A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU5418486A (en)	1987-04-16
DK98886D0 (da)	1986-03-04
DK175201B1 (da)	2004-07-05
IE58981B1 (en)	1993-12-15
IE860535L (en)	1987-04-15
JPS6287514A (ja)	1987-04-22
EP0219922A3 (en)	1987-10-28
EP0219922A2 (en)	1987-04-29
NO862193D0 (no)	1986-06-03
NO172729B (no)	1993-05-24
JPH0761947B2 (ja)	1995-07-05
KR870003775A (ko)	1987-05-04
US4769250A (en)	1988-09-06
EP0219922B2 (en)	2002-08-28
AU587232B2 (en)	1989-08-10
ATE65392T1 (de)	1991-08-15
DK98886A (da)	1987-04-16
DE3680447D1 (de)	1991-08-29
NO172729C (no)	1993-09-01
EP0219922B1 (en)	1991-07-24
KR890004689B1 (ko)	1989-11-25

Legal Events

Date	Code	Title	Description
2006-06-26	MK1K	Patent expired

Publication	Publication Date	Title
NO862193D0 (no)	1986-06-03	Antracyklingholdig preparater og fremgangsmaate for deres fremstilling.
NO873492L (no)	1988-02-22	Fremgangsmaate for fremstilling av antifungale preparater.
Racker	1973	A new procedure for the reconstitution of biologically active phospholipid vesicles
NL300036I1 (nl)	2001-03-01	Liposomale formuleringen met een hoge anti-neoplastisch middel/lipideverhouding.
DK86988D0 (da)	1988-02-19	Liposompraeparat og anvendelse deraf
GR1000074B (el)	1990-10-31	Λιποειδη σφαιριδια (κυστιδια) για ενδοπεριτονειακη χορηγηση θεραπευτικων παραγοντων.
DK15087A (da)	1987-07-15	Immunogenkomplekser og deres anvendelse i laegemidler, isaer vacciner
ATE141166T1 (de)	1996-08-15	Guanidinaminoglycosid enthaltende liposome
GR1001503B (el)	1994-02-28	Μέ?οδος δια την παρασκευή φαρμακευτικών ενώσεων αι οποίαι περιέχουν ως δραστική ουσία καρβονικά οξέα τα οποία περιέχουν ?είον κα?ώς και η χρησιμοποίησις αυτών δια την καταπολέμησιν των ρετροιών.
AR241117A2 (es)	1991-11-15	Procedimiento para la preparacion de complejos de flavanolignanos con fosfolipidos
KR950700725A (ko)	1995-02-20	리포솜 조성물(liposome composition)
FI872576A0 (fi)	1987-06-09	Peptider med inverkan pao diures och natriures, foerfarande foer framstaellning av dessa och medel innehaollande dessa och deras anvaendning.
DK122190A (da)	1990-07-17	Phospholipid-indesluttet cationisk, lipofilt farmaceutisk praeparat og fremgangsmaade til fremstilling af samme
DE3851842D1 (de)	1994-11-17	Wässrige bereitung von liposomenzusammensetzungen.