DK98886A - Antineoplastiske anthracyclin-midler indkapslet i micellulaere phospholipidpartikler og fremgangsmaader til deres anvendelse ved tumor-terapi - Google Patents

Antineoplastiske anthracyclin-midler indkapslet i micellulaere phospholipidpartikler og fremgangsmaader til deres anvendelse ved tumor-terapi Download PDF

Info

Publication number: DK98886A
Authority: DK; Denmark
Prior art keywords: micellular; procedures; tumor therapy; agents included; particles
Prior art date: 1985-10-15

Application number

DK098886A

Other languages

English (en)

Other versions

DK175201B1 (da

DK98886D0 (da

Inventor

Eric Forssen

Original Assignee

Vestar Research Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-15

Filing date

1986-03-04

Publication date

1987-04-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25141806&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK98886(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-03-04 Application filed by Vestar Research Inc filed Critical Vestar Research Inc

1986-03-04 Publication of DK98886D0 publication Critical patent/DK98886D0/da

1987-04-16 Publication of DK98886A publication Critical patent/DK98886A/da

2004-07-05 Application granted granted Critical

2004-07-05 Publication of DK175201B1 publication Critical patent/DK175201B1/da

Links

229940045799 anthracyclines and related substance Drugs 0.000 title abstract 3
239000002245 particle Substances 0.000 title abstract 3
150000003904 phospholipids Chemical class 0.000 title abstract 2
206010028980 Neoplasm Diseases 0.000 title 1
230000000118 anti-neoplastic effect Effects 0.000 title 1
238000000034 method Methods 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
HVVJCLFLKMGEIY-UHFFFAOYSA-N 2,3-dioctadecoxypropyl 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CCCCCCCCCCCCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)OCCCCCCCCCCCCCCCCCC HVVJCLFLKMGEIY-UHFFFAOYSA-N 0.000 abstract 1
STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 abstract 1
AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 abstract 1
229940034982 antineoplastic agent Drugs 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
229960000975 daunorubicin Drugs 0.000 abstract 1
STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
239000008121 dextrose Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK198600988A 1985-10-15 1986-03-04 Kompositioner omfattende antineoplastiske anthracyclinmidler indkapslet i micellulære phospholipidpartikler og fremgangsmåder til fremstilling deraf DK175201B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US78753585A	1985-10-15	1985-10-15
US78753585		1985-10-15

Publications (3)

Publication Number	Publication Date
DK98886D0 DK98886D0 (da)	1986-03-04
DK98886A true DK98886A (da)	1987-04-16
DK175201B1 DK175201B1 (da)	2004-07-05

Family

ID=25141806

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198600988A DK175201B1 (da)	1985-10-15	1986-03-04	Kompositioner omfattende antineoplastiske anthracyclinmidler indkapslet i micellulære phospholipidpartikler og fremgangsmåder til fremstilling deraf

Country Status (10)

Country	Link
US (1)	US4769250A (da)
EP (1)	EP0219922B2 (da)
JP (1)	JPH0761947B2 (da)
KR (1)	KR890004689B1 (da)
AT (1)	ATE65392T1 (da)
AU (1)	AU587232B2 (da)
DE (1)	DE3680447D1 (da)
DK (1)	DK175201B1 (da)
IE (1)	IE58981B1 (da)
NO (1)	NO172729C (da)

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US11980636B2 (en)	2020-11-18	2024-05-14	Jazz Pharmaceuticals Ireland Limited	Treatment of hematological disorders
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1986
- 1986-02-27 IE IE53586A patent/IE58981B1/en not_active IP Right Cessation
- 1986-02-28 AU AU54184/86A patent/AU587232B2/en not_active Expired
- 1986-03-04 DK DK198600988A patent/DK175201B1/da not_active IP Right Cessation
- 1986-03-04 EP EP86301513A patent/EP0219922B2/en not_active Expired - Lifetime
- 1986-03-04 AT AT86301513T patent/ATE65392T1/de not_active IP Right Cessation
- 1986-03-04 DE DE8686301513T patent/DE3680447D1/de not_active Expired - Lifetime
- 1986-03-10 JP JP61052346A patent/JPH0761947B2/ja not_active Expired - Lifetime
- 1986-03-31 KR KR1019860002412A patent/KR890004689B1/ko not_active Expired
- 1986-06-03 NO NO862193A patent/NO172729C/no not_active IP Right Cessation
1987
- 1987-10-26 US US07/112,073 patent/US4769250A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR870003775A (ko)	1987-05-04
EP0219922A2 (en)	1987-04-29
IE860535L (en)	1987-04-15
NO862193D0 (no)	1986-06-03
JPH0761947B2 (ja)	1995-07-05
IE58981B1 (en)	1993-12-15
US4769250A (en)	1988-09-06
KR890004689B1 (ko)	1989-11-25
ATE65392T1 (de)	1991-08-15
EP0219922A3 (en)	1987-10-28
DE3680447D1 (de)	1991-08-29
EP0219922B2 (en)	2002-08-28
AU5418486A (en)	1987-04-16
DK175201B1 (da)	2004-07-05
NO862193L (no)	1987-04-21
NO172729C (no)	1993-09-01
NO172729B (no)	1993-05-24
EP0219922B1 (en)	1991-07-24
AU587232B2 (en)	1989-08-10
DK98886D0 (da)	1986-03-04
JPS6287514A (ja)	1987-04-22

Legal Events

Date	Code	Title	Description
2006-03-20	PUP	Patent expired

Publication	Publication Date	Title
DK98886A (da)	1987-04-16	Antineoplastiske anthracyclin-midler indkapslet i micellulaere phospholipidpartikler og fremgangsmaader til deres anvendelse ved tumor-terapi
GR1000074B (el)	1990-10-31	Λιποειδη σφαιριδια (κυστιδια) για ενδοπεριτονειακη χορηγηση θεραπευτικων παραγοντων.
EP0260811A3 (en)	1988-07-20	Phospholipid particles encapsulating polyene antibiotics for the treatment of systemic fungal infections
GR1001503B (el)	1994-02-28	Μέ?οδος δια την παρασκευή φαρμακευτικών ενώσεων αι οποίαι περιέχουν ως δραστική ουσία καρβονικά οξέα τα οποία περιέχουν ?είον κα?ώς και η χρησιμοποίησις αυτών δια την καταπολέμησιν των ρετροιών.
DE3855265D1 (de)	1996-06-13	Liposomen-Formulierungen mit hohem antineoplastischem Wirkstoff/Lipid-Verhältnis
DK86988D0 (da)	1988-02-19	Liposompraeparat og anvendelse deraf
DE3782492D1 (de)	1992-12-10	Liposom-anthrachinon-arzneimittel-zusammensetzung und herstellung.
DK524884A (da)	1985-05-18	Farmaceutiske praeparater indeholdende phosphatidylserin og fremgangsmaade til fremstilling deraf
CO4480019A1 (es)	1997-07-09	Liposomas de cetoprofeno
DK122190A (da)	1990-07-17	Phospholipid-indesluttet cationisk, lipofilt farmaceutisk praeparat og fremgangsmaade til fremstilling af samme
DK329985A (da)	1985-07-19	Antitumor-farmaceutiske midler og fremgangsmaade til deres fremstilling
IT1260155B (it)	1996-03-28	Uso terapeutico della fosforil-l-serina-n-acil-sfingosina
PT100155A (pt)	1993-05-31	Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do carcinoma das celulas nao pequenas do pulmao e composicoes farmaceuticas
DE3851842D1 (de)	1994-11-17	Wässrige bereitung von liposomenzusammensetzungen.
ATE70456T1 (de)	1992-01-15	Verwendung von micellaren partikeln zur herstellung von zusammensetzungen zum beschiessen von tumoren in menschen und deren verwendung.
DK299590D0 (da)	1990-12-18	Phospholipidderivater, fremgangsmaade til deres fremstilling og terapeutiske praeparater indeholdende disse
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