NO865122L - Beskyttelse av methionin i en polypeptidkjede mot irreversibel oxydasjon. - Google Patents

Beskyttelse av methionin i en polypeptidkjede mot irreversibel oxydasjon.

Info

Publication number: NO865122L
Authority: NO; Norway
Prior art keywords: irreversible; chain; polypeptime; oxydation; methionin
Prior art date: 1985-12-18

Application number

NO865122A

Other languages

English (en)

Norwegian (no)

Other versions

NO865122D0 (no

Inventor

Umberto Canosi

Stefano Villa

Original Assignee

Serono Cesare Ist Ricerca

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-18

Filing date

1986-12-17

Publication date

1987-06-19

1986-12-17 Application filed by Serono Cesare Ist Ricerca filed Critical Serono Cesare Ist Ricerca

1986-12-17 Publication of NO865122D0 publication Critical patent/NO865122D0/no

1987-06-19 Publication of NO865122L publication Critical patent/NO865122L/no

Links

230000002427 irreversible effect Effects 0.000 title abstract 2
229930182817 methionine Natural products 0.000 title abstract 2
XUYPXLNMDZIRQH-LURJTMIESA-N N-acetyl-L-methionine Chemical compound CSCC[C@@H](C(O)=O)NC(C)=O XUYPXLNMDZIRQH-LURJTMIESA-N 0.000 title 1
238000007254 oxidation reaction Methods 0.000 title 1
DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 abstract 2
JUIKUQOUMZUFQT-UHFFFAOYSA-N 2-bromoacetamide Chemical compound NC(=O)CBr JUIKUQOUMZUFQT-UHFFFAOYSA-N 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical class S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 abstract 1
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000029936 alkylation Effects 0.000 abstract 1
238000005804 alkylation reaction Methods 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000010511 deprotection reaction Methods 0.000 abstract 1
VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 abstract 1
PGLTVOMIXTUURA-UHFFFAOYSA-N iodoacetamide Chemical compound NC(=O)CI PGLTVOMIXTUURA-UHFFFAOYSA-N 0.000 abstract 1
INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 1
125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
150000003573 thiols Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)
Adhesives Or Adhesive Processes (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO865122A 1985-12-18 1986-12-17 Beskyttelse av methionin i en polypeptidkjede mot irreversibel oxydasjon. NO865122L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT48955/85A IT1200162B (it)	1985-12-18	1985-12-18	Protezione della metionina in una catena polipeptidica dalla ossidazione irreversibile

Publications (2)

Publication Number	Publication Date
NO865122D0 NO865122D0 (no)	1986-12-17
NO865122L true NO865122L (no)	1987-06-19

Family

ID=11269152

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO865122A NO865122L (no)	1985-12-18	1986-12-17	Beskyttelse av methionin i en polypeptidkjede mot irreversibel oxydasjon.

Country Status (12)

Country	Link
EP (1)	EP0226827B1 (de)
JP (1)	JPS62201898A (de)
AT (1)	ATE85343T1 (de)
AU (1)	AU606851B2 (de)
DE (1)	DE3687702T2 (de)
DK (1)	DK572286A (de)
ES (1)	ES2001460A6 (de)
FI (1)	FI94134C (de)
IL (1)	IL80742A0 (de)
IT (1)	IT1200162B (de)
NO (1)	NO865122L (de)
ZA (1)	ZA868958B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2831090A4 (de) *	2012-03-26	2015-11-11	Univ California	Herstellung von funktionalisierten polypeptiden, peptiden und proteinen durch alkylierung von thioethergruppen
US9718921B2 (en)	2013-02-26	2017-08-01	The Regents Of The University Of California	Amphiphilic derivatives of thioether containing block copolypeptides
US10351591B2 (en)	2015-03-20	2019-07-16	The Regents Of The University Of California	Polypeptides, peptides, and proteins functionalized by alkylation of thioether groups via ring-opening reactions
EP3124495A1 (de)	2015-07-31	2017-02-01	Centre National de la Recherche Scientifique (C.N.R.S.)	Derivate von elastin-ähnlichen polypeptiden und verwendungen davon
EP3448872A4 (de)	2016-04-27	2019-12-11	The Regents of the University of California	Herstellung von funktionellen homocysteinresten in polypeptiden und peptiden

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1234977B (it) *	1985-03-22	1992-06-09	Serono Ist Farm	Espressione in e. coli polipeptidi ibridi contenenti la sequenza del fattore di rilascio dell'ormone della crescita

1985
- 1985-12-18 IT IT48955/85A patent/IT1200162B/it active
1986
- 1986-11-20 AT AT86116075T patent/ATE85343T1/de not_active IP Right Cessation
- 1986-11-20 EP EP86116075A patent/EP0226827B1/de not_active Expired - Lifetime
- 1986-11-20 DE DE8686116075T patent/DE3687702T2/de not_active Expired - Fee Related
- 1986-11-24 IL IL80742A patent/IL80742A0/xx not_active IP Right Cessation
- 1986-11-26 ZA ZA868958A patent/ZA868958B/xx unknown
- 1986-11-27 DK DK572286A patent/DK572286A/da not_active Application Discontinuation
- 1986-12-04 AU AU66089/86A patent/AU606851B2/en not_active Ceased
- 1986-12-17 NO NO865122A patent/NO865122L/no unknown
- 1986-12-17 ES ES8603467A patent/ES2001460A6/es not_active Expired
- 1986-12-17 JP JP61299018A patent/JPS62201898A/ja active Pending
- 1986-12-18 FI FI865200A patent/FI94134C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO865122D0 (no)	1986-12-17
FI94134B (fi)	1995-04-13
ATE85343T1 (de)	1993-02-15
FI865200A0 (fi)	1986-12-18
IL80742A0 (en)	1987-02-27
DE3687702D1 (de)	1993-03-18
AU606851B2 (en)	1991-02-21
EP0226827A3 (en)	1988-08-31
FI94134C (fi)	1995-07-25
IT1200162B (it)	1989-01-05
EP0226827B1 (de)	1993-02-03
FI865200L (fi)	1987-06-19
IT8548955A0 (it)	1985-12-18
DK572286D0 (da)	1986-11-27
ZA868958B (en)	1987-07-29
AU6608986A (en)	1987-06-25
DE3687702T2 (de)	1993-06-09
DK572286A (da)	1987-06-19
JPS62201898A (ja)	1987-09-05
EP0226827A2 (de)	1987-07-01
ES2001460A6 (es)	1988-05-16

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