NO873568L - Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav. - Google Patents

Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav.

Info

Publication number: NO873568L
Authority: NO; Norway
Prior art keywords: loweralkyl; hydrogen; quinolinmethanols; aralkylamino; alkanols
Prior art date: 1986-08-25

Application number

NO873568A

Other languages

English (en)

Norwegian (no)

Other versions

NO873568D0 (no

Inventor

Richard Charles Effland

Joseph Thomas Klein

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-25

Filing date

1987-08-24

Publication date

1988-02-26

1987-08-24 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1987-08-24 Publication of NO873568D0 publication Critical patent/NO873568D0/no

1988-02-26 Publication of NO873568L publication Critical patent/NO873568L/no

Links

238000000034 method Methods 0.000 title 1
150000002431 hydrogen Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
208000024827 Alzheimer disease Diseases 0.000 abstract 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002708 enhancing effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Quinoline Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Photoreceptors In Electrophotography (AREA)

NO873568A 1986-08-25 1987-08-24 Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav. NO873568L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/899,584 US4789678A (en)	1986-08-25	1986-08-25	Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Publications (2)

Publication Number	Publication Date
NO873568D0 NO873568D0 (no)	1987-08-24
NO873568L true NO873568L (no)	1988-02-26

Family

ID=25411249

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO873568A NO873568L (no)	1986-08-25	1987-08-24	Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav.

Country Status (19)

Country	Link
US (1)	US4789678A (de)
EP (1)	EP0258755B1 (de)
JP (1)	JPS6360968A (de)
KR (1)	KR880002834A (de)
AT (2)	ATE67189T1 (de)
AU (1)	AU589029B2 (de)
CA (1)	CA1297111C (de)
DE (1)	DE3772905D1 (de)
DK (1)	DK441187A (de)
ES (1)	ES2029812T3 (de)
FI (1)	FI86299C (de)
GR (1)	GR3003299T3 (de)
HU (1)	HU199425B (de)
IL (1)	IL83629A (de)
NO (1)	NO873568L (de)
NZ (1)	NZ221543A (de)
PH (1)	PH25571A (de)
PT (1)	PT85583B (de)
ZA (1)	ZA876254B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2581382B1 (fr) *	1985-05-06	1987-06-26	Sanofi Sa	Derives n-(quinolyl) glycinamides, leur procede de preparation et leur application therapeutique en tant que psychotropes
GB8610981D0 (en) *	1986-05-06	1986-06-11	Ici America Inc	Quinoline amides
GB8621425D0 (en) *	1986-09-05	1986-10-15	Smith Kline French Lab	Compounds
US4743601A (en) *	1987-07-13	1988-05-10	Hoechst-Roussel Pharmaceuticals Inc.	Dihydro-1,4-oxazino(2,3-C)quinolines
US4942168A (en) *	1987-07-13	1990-07-17	Hoechst-Roussel Pharmaceuticals Inc.	Hydroxyquinoline amines, and method of enhancing memory in mammals
GB8804445D0 (en) *	1988-02-25	1988-03-23	Smithkline Beckman Intercredit	Compounds
GB8804443D0 (en) *	1988-02-25	1988-03-23	Smithkline Beckman Intercredit	Compounds
US5019574A (en) *	1988-09-30	1991-05-28	Chugai Seiyaku Kabushiki Kaisha	3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function
CA2011086A1 (en) *	1989-03-17	1990-09-17	Karl-Heinz Geiss	2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
US4916135A (en) *	1989-05-08	1990-04-10	Hoechst Roussel Pharmaceuticals Inc.	N-heteroaryl-4-quinolinamines
GB8918265D0 (en) *	1989-08-10	1989-09-20	Smithkline Beckman Intercredit	Compounds
US5110815A (en) *	1990-12-03	1992-05-05	Hoechst-Roussel Pharmaceuticals Inc.	5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use
GB9122051D0 (en) *	1991-10-17	1991-11-27	Univ Nottingham	Medicines
US5493027A (en) *	1993-01-22	1996-02-20	Board Of Regents, The University Of Texas System	Anticonvulsive agents and uses thereof
HUP0203045A3 (en) *	1999-09-22	2004-06-28	Sanofi Aventis Deutschland	4-benzylaminoquinoline conjugates with bile acid and their heteroanalogues, methods for producing the same, medicaments containing these compounds and their use
US8420670B2 (en)	2007-08-22	2013-04-16	Abbott Laboratories	4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy
MX2010010773A (es)	2008-04-01	2011-04-11	Abbott Gmbh & Co Kg	Tetrahidroisoquinolinas, composiciones farmaceuticas que las contienen y su uso en terapia.
AR075442A1 (es)	2009-02-16	2011-03-30	Abbott Gmbh & Co Kg	Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
US9045459B2 (en)	2010-08-13	2015-06-02	AbbVie Deutschland GmbH & Co. KG	Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en)	2010-08-13	2014-09-30	Abbott Laboratories	Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en)	2010-08-13	2014-11-11	Abbott Laboratories	Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8877794B2 (en)	2010-08-13	2014-11-04	Abbott Laboratories	Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en)	2010-08-13	2015-06-09	AbbVie Deutschland GmbH & Co. KG	Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en)	2011-05-12	2016-04-12	AbbVie Deutschland GmbH & Co. KG	Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
US8853196B2 (en)	2011-08-05	2014-10-07	AbbVie Deutschland GmbH & Co. KG	Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2014006004A (es)	2011-11-18	2015-04-16	Abbvie Deutschland	Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia.
US9365512B2 (en)	2012-02-13	2016-06-14	AbbVie Deutschland GmbH & Co. KG	Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
US9650334B2 (en)	2013-03-15	2017-05-16	Abbvie Inc.	Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en)	2013-03-15	2017-05-23	Abbvie Inc.	Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
EP3057960B1 (de)	2013-10-17	2019-02-27	AbbVie Deutschland GmbH & Co. KG	Aminochroman-, aminothiochroman- und amino-1,2,3,4-tetrahydrochinolin-derivate, pharmazeutische zusammensetzungen damit und verwendung in der therapie
MX2016004934A (es)	2013-10-17	2016-12-20	Abbvie Deutschland	Derivados de aminotetralina y aminoindano, composiciones farmaceuticas que los contienen, y su uso en terapia.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2785165A (en) *	1953-12-22	1957-03-12	Abbott Lab	Preparation of 4-aminoquinoline
US3391146A (en) *	1964-11-10	1968-07-02	Bristol Myers Co	Nu-substituted carbamates and thiocarbamates of 2-quinolinemethanols
US4180670A (en) *	1977-02-02	1979-12-25	John Wyeth & Brother Limited	Amino pyridine derivatives
FR2498187A1 (fr) *	1981-01-16	1982-07-23	Rhone Poulenc Sante	Procede de preparation d'amino-4 chloro-7 quinoleines
US4631286A (en) *	1984-10-25	1986-12-23	Hoechst-Roussel Pharmaceuticals Inc.	9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
DE3582995D1 (de) *	1984-10-25	1991-07-04	Hoechst Roussel Pharma	9-amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte verbindungen, verfahren zu ihrer herstellung und verwendung als arzneimittel.
US4695573A (en) *	1984-10-25	1987-09-22	Hoechst-Roussel Pharmaceuticals Inc.	9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
GB8621425D0 (en) *	1986-09-05	1986-10-15	Smith Kline French Lab	Compounds
US4816456A (en) *	1986-10-01	1989-03-28	Summers William K	Administration of monoamine acridines in cholinergic neuronal deficit states

1986
- 1986-08-25 US US06/899,584 patent/US4789678A/en not_active Expired - Fee Related
1987
- 1987-08-21 EP EP87112131A patent/EP0258755B1/de not_active Expired - Lifetime
- 1987-08-21 ES ES198787112131T patent/ES2029812T3/es not_active Expired - Lifetime
- 1987-08-21 DE DE8787112131T patent/DE3772905D1/de not_active Expired - Fee Related
- 1987-08-21 AT AT87112131T patent/ATE67189T1/de active
- 1987-08-21 FI FI873631A patent/FI86299C/fi not_active IP Right Cessation
- 1987-08-24 ZA ZA876254A patent/ZA876254B/xx unknown
- 1987-08-24 NZ NZ221543A patent/NZ221543A/xx unknown
- 1987-08-24 CA CA000545157A patent/CA1297111C/en not_active Expired - Lifetime
- 1987-08-24 IL IL83629A patent/IL83629A/xx not_active IP Right Cessation
- 1987-08-24 HU HU873738A patent/HU199425B/hu not_active IP Right Cessation
- 1987-08-24 JP JP62208386A patent/JPS6360968A/ja active Pending
- 1987-08-24 KR KR870009224A patent/KR880002834A/ko not_active Withdrawn
- 1987-08-24 AU AU77343/87A patent/AU589029B2/en not_active Ceased
- 1987-08-24 NO NO873568A patent/NO873568L/no unknown
- 1987-08-24 DK DK441187A patent/DK441187A/da not_active Application Discontinuation
- 1987-08-24 PH PH35724A patent/PH25571A/en unknown
- 1987-08-25 PT PT85583A patent/PT85583B/pt not_active IP Right Cessation
- 1987-10-08 AT AT0260187A patent/AT388729B/de not_active IP Right Cessation
1991
- 1991-12-11 GR GR91401396T patent/GR3003299T3/el unknown

Also Published As

Publication number	Publication date
HU199425B (en)	1990-02-28
AU7734387A (en)	1988-02-25
DK441187D0 (da)	1987-08-24
FI86299B (fi)	1992-04-30
ATA260187A (de)	1989-01-15
EP0258755A1 (de)	1988-03-09
US4789678A (en)	1988-12-06
FI86299C (fi)	1992-08-10
DK441187A (da)	1988-02-26
ES2029812T3 (es)	1992-10-01
PH25571A (en)	1991-08-08
JPS6360968A (ja)	1988-03-17
NZ221543A (en)	1990-09-26
PT85583B (pt)	1990-05-31
FI873631A7 (fi)	1988-02-26
HUT45503A (en)	1988-07-28
ATE67189T1 (de)	1991-09-15
IL83629A (en)	1992-02-16
GR3003299T3 (en)	1993-02-17
NO873568D0 (no)	1987-08-24
AT388729B (de)	1989-08-25
ZA876254B (en)	1988-04-27
KR880002834A (ko)	1988-05-11
FI873631A0 (fi)	1987-08-21
IL83629A0 (en)	1988-01-31
CA1297111C (en)	1992-03-10
EP0258755B1 (de)	1991-09-11
DE3772905D1 (de)	1991-10-17
AU589029B2 (en)	1989-09-28
PT85583A (en)	1987-09-01

Publication	Publication Date	Title
NO873568D0 (no)	1987-08-24	Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav.
ES2132284T3 (es)	1999-08-16	Derivados de carbamato de 2-(piperidin-4-il, piridin-4-il y tetrahidropiridin-4-il)-benzofurano-7, su preparacion y su uso como inhibidores de acetilcolinesterasa.
NO874872D0 (no)	1987-11-23	Kondenderte heterocykliske tetrahydroaminokinolinoler og beslektede forbindelser samt fremgangsmaate for fremstilling derav.
PT92234A (pt)	1990-05-31	Processo para a preparacao de 1,2,3,4-tetraidro-1,9-acridinodiaminas
NO902813D0 (no)	1990-06-25	(1,2,3,4-tetrahydro-9-acridinimino)cykloheksankarboksylsyre og relaterte forbindelser, fremgangsmaate for fremstilling og anvendelse som medikamenter.
DK592589D0 (da)	1989-11-24	Kondenserede heterocycliske derivater af 1,2,3,4-tetrahydroacridin, deres fremstilling og anvendelse
NO902556D0 (no)	1990-06-08	4,5,5a,6-tetrahydro-3h-isoksazol(5,4,3-kl)akridinderivater og fremgangsmaate for fremstilling derav.
DK571989D0 (da)	1989-11-15	Hydroxy-1,2,3,4-tetrahydroaminoacridiner, deres fremstilling og anvendelse
ATE130002T1 (de)	1995-11-15	1-(pyridinylalkyl)-1h-indole, -indoline und analoge.
FI861001A0 (fi)	1986-03-11	Benzo/c/-1,5-naftyridiner, foerfarande foer deras framstaellning och i deras framstaellning anvaendbara mellanprodukter samt deras anvaendning saosom laekemedel.