NO884497L - Dideoksycytidin-derivater. - Google Patents

Dideoksycytidin-derivater.

Info

Publication number
NO884497L
NO884497L NO88884497A NO884497A NO884497L NO 884497 L NO884497 L NO 884497L NO 88884497 A NO88884497 A NO 88884497A NO 884497 A NO884497 A NO 884497A NO 884497 L NO884497 L NO 884497L
Authority
NO
Norway
Prior art keywords
dideoxycytidine
didehydro
cytidine
methylene
dideoxy
Prior art date
Application number
NO88884497A
Other languages
English (en)
Norwegian (no)
Other versions
NO884497D0 (no
Inventor
John J Partridge
Steve Tam
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO884497D0 publication Critical patent/NO884497D0/no
Publication of NO884497L publication Critical patent/NO884497L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO88884497A 1987-10-09 1988-10-07 Dideoksycytidin-derivater. NO884497L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10722187A 1987-10-09 1987-10-09

Publications (2)

Publication Number Publication Date
NO884497D0 NO884497D0 (no) 1988-10-07
NO884497L true NO884497L (no) 1989-04-10

Family

ID=22315505

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88884497A NO884497L (no) 1987-10-09 1988-10-07 Dideoksycytidin-derivater.

Country Status (14)

Country Link
EP (1) EP0311100A3 (fr)
JP (1) JPH01132597A (fr)
KR (1) KR890006624A (fr)
AU (1) AU2355488A (fr)
DK (1) DK564088A (fr)
FI (1) FI884627L (fr)
HU (1) HU201090B (fr)
IL (1) IL87949A0 (fr)
MC (1) MC1982A1 (fr)
NO (1) NO884497L (fr)
NZ (1) NZ226481A (fr)
PT (1) PT88716B (fr)
YU (1) YU187788A (fr)
ZA (1) ZA886890B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US6448392B1 (en) 1985-03-06 2002-09-10 Chimerix, Inc. Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use
NZ223910A (en) * 1987-03-20 1991-02-26 Bristol Myers Co 2',3'-dideoxynucleosides, process for their production and intermediates therefor
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
EP0500610A1 (fr) * 1989-11-06 1992-09-02 Nycomed Imaging As Derives de nucleosides
US5192764A (en) * 1991-05-30 1993-03-09 Research Foundation Of State Of N.Y. Pyrazinone n-oxide nucleosides and analogs thereof
RU2085557C1 (ru) * 1991-09-30 1997-07-27 Санкио Компани Лимитед Производные нуклеозидов пиримидина или их фармацевтически приемлемые соли и способ их получения
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
AU1412299A (en) * 1997-11-25 1999-06-15 Protarga, Inc. Nucleoside analog compositions and uses thereof
JP4634694B2 (ja) 2001-03-23 2011-02-16 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪アルコール薬物複合体
US8552054B2 (en) 2001-03-23 2013-10-08 Luitpold Pharmaceuticals, Inc. Fatty amine drug conjugates
EP1569652A4 (fr) 2001-12-14 2008-07-02 Pharmasset Inc Nucleosides n sp 4 /sp -acylcytosines pour le traitement d'infections virales
US9326983B2 (en) 2013-08-01 2016-05-03 University Of Kentucky Research Foundation Compositions and methods for treating retinal degradation
DK3261644T3 (da) * 2015-02-26 2021-06-28 Univ Kentucky Res Found Sammensætninger og fremgangsmåder til behandling af nethindenedbrydning
US11219623B2 (en) 2015-02-26 2022-01-11 University Of Kentucky Research Foundation Inflammasome inhibition for the treatment of Parkinson's disease, Alzheimer's disease and multiple sclerosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ216172A (en) * 1985-05-15 1989-08-29 Wellcome Found Nucleosides and pharmaceutical compositions
DE3850571T2 (de) * 1987-03-24 1994-10-27 Nycomed Imaging As 2',3'-dideoxyribofuranoxid-derivate.
EP0294113A1 (fr) * 1987-05-29 1988-12-07 The Wellcome Foundation Limited Nucléosides thérapeutiques
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds

Also Published As

Publication number Publication date
FI884627A0 (fi) 1988-10-07
DK564088A (da) 1989-04-10
DK564088D0 (da) 1988-10-07
MC1982A1 (fr) 1989-11-23
PT88716B (pt) 1992-12-31
NZ226481A (en) 1992-01-29
AU2355488A (en) 1989-04-13
YU187788A (en) 1990-04-30
EP0311100A3 (fr) 1990-10-31
EP0311100A2 (fr) 1989-04-12
IL87949A0 (en) 1989-03-31
NO884497D0 (no) 1988-10-07
ZA886890B (en) 1989-05-30
HU201090B (en) 1990-09-28
KR890006624A (ko) 1989-06-14
HUT47592A (en) 1989-03-28
FI884627A7 (fi) 1989-04-10
FI884627L (fi) 1989-04-10
JPH01132597A (ja) 1989-05-25

Similar Documents

Publication Publication Date Title
RU2144027C1 (ru) Изохинолины, способ их получения и фармацевтическая композиция на их основе
HU201090B (en) Process for producing dideoxocytidine derivatives and pharmaceutical compositions comprising same as active ingredient
IL128652A (en) History of adenosine substituted N6 heterocyclic and pharmaceutical preparations containing them
JP2007526291A (ja) アデノシン受容体アゴニスト
IE49701B1 (en) Amides of acyl-carnitines,process for preparing same and pharmaceutical compositions containing such amides
NO144211B (no) Analogifremgangsmaate til fremstilling av nye tyrosinderivater med farmasoeytisk virkning paa glatte muskler
CN115960148B (zh) 一种新型的胞苷衍生物及其药物组合物和用途
JPS6229566A (ja) 新規グアニジノメチル安息香酸誘導体
US4315920A (en) Adenosine deaminase inhibitors
JPH02124884A (ja) Ｎ―置換アミド誘導体
US3956277A (en) Purine sugar derivatives
JP3885900B2 (ja) ベンゾピラン誘導体及びそれを有効成分とする心臓疾患治療剤
PT100216B (pt) N-{{4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil} carbonil}-aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem
US4086416A (en) Septacidin analogs
HU180617B (en) Process for producing 1,2-bis-bracket-nicotinamido-bracket closed-propane,salts and pharmaceutical compositions containing them
Wu et al. Discovery, synthesis, and biological mechanism evaluation of novel quinoline derivatives as potent NLRP3 inhibitors
CN117343072B (zh) 一种1-取代肉桂酰基-2-氧代石蒜碱类化合物及其制备方法和应用
US4539402A (en) Quinazolinone derivatives
SK146096A3 (en) Adenosine derivatives, processes for their preparation, their use for the preparation of drugs, their use in therapy and pharmaceutical compositions containing them
KR870001935B1 (ko) 항포진성을 갖는 뉴클레오시 유도체 및 그의 산부가염의 제조방법
CN104211748B (zh) 6‑羟基双脱氧鸟嘌呤核苷磷酸酯制备和用途
US4992446A (en) Tricyclic quinolizine amides
FI70019C (fi) Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara och isynnerhet vid behandling av psoriasis laempliga poycykliska foereningar och mellanprodukter som anvaends vi d oerfarandet
CA2373015A1 (fr) Dihydrate derive de purine, medicaments le contenant comme principe actif et intermediaire utilise dans sa preparation
JPS6117832B2 (fr)