NO890801L - Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer. - Google Patents

Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer.

Info

Publication number
NO890801L
NO890801L NO89890801A NO890801A NO890801L NO 890801 L NO890801 L NO 890801L NO 89890801 A NO89890801 A NO 89890801A NO 890801 A NO890801 A NO 890801A NO 890801 L NO890801 L NO 890801L
Authority
NO
Norway
Prior art keywords
preparation
group
hydrogen
lysyloxydase
inhibitors
Prior art date
Application number
NO89890801A
Other languages
English (en)
Norwegian (no)
Other versions
NO890801D0 (no
Inventor
Michael G Palfreyman
Ian A Mcdonald
Philippe Bey
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO890801D0 publication Critical patent/NO890801D0/no
Publication of NO890801L publication Critical patent/NO890801L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
NO89890801A 1988-02-25 1989-02-24 Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer. NO890801L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16038288A 1988-02-25 1988-02-25
US16036488A 1988-02-25 1988-02-25

Publications (2)

Publication Number Publication Date
NO890801D0 NO890801D0 (no) 1989-02-24
NO890801L true NO890801L (no) 1989-08-28

Family

ID=26856831

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89890801A NO890801L (no) 1988-02-25 1989-02-24 Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer.

Country Status (17)

Country Link
EP (1) EP0330218B1 (de)
JP (1) JP2772660B2 (de)
KR (1) KR890012641A (de)
CN (1) CN1035497A (de)
AT (1) ATE117549T1 (de)
AU (1) AU618076B2 (de)
CA (1) CA1338647C (de)
DE (1) DE68920757T2 (de)
DK (1) DK89489A (de)
ES (1) ES2070134T3 (de)
FI (1) FI890827A7 (de)
GR (1) GR3015470T3 (de)
IE (1) IE65553B1 (de)
IL (1) IL89388A (de)
NO (1) NO890801L (de)
NZ (1) NZ228068A (de)
PT (1) PT89839B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011504485A (ja) 2007-11-21 2011-02-10 ファーマクシス リミテッド Ssao/vap−1のハロアリルアミン阻害剤およびその用途
BR112017019150B1 (pt) * 2015-03-06 2023-05-09 Pharmakea, Inc Compostos inibidores de lisil oxidase-like 2 fluorados, composição farmacêutica e uso desses compostos
GB201602934D0 (en) 2016-02-19 2016-04-06 Cancer Res Inst Royal Compounds
JP2020508996A (ja) * 2017-03-02 2020-03-26 ファーマクシス リミテッド リシルオキシダーゼのハロアリルアミンピラゾール誘導体阻害剤およびその使用
GB201809295D0 (en) 2018-06-06 2018-07-25 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
GB201818750D0 (en) 2018-11-16 2019-01-02 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
JP2025528475A (ja) * 2022-08-29 2025-08-28 シンタラ・リミテッド リシルオキシダーゼの新規選択的阻害剤
CN119732928A (zh) * 2024-12-26 2025-04-01 国家纳米科学中心 一种抑制胶原纤维形成的药物分子及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891064A (en) * 1956-05-28 1959-06-16 Dow Chemical Co 3, 3-dichloro-2-methylallylamines
US4454158A (en) * 1981-06-01 1984-06-12 Merrell Toraude Et Compagnie Allyl amine MAO inhibitors
US4650907A (en) * 1985-12-05 1987-03-17 Merrell Dow Pharmaceuticals Inc. Nonaromatic fluoroallylamine MAO inhibitors
DD246990A1 (de) * 1986-02-26 1987-06-24 Univ Leipzig Verfahren zur herstellung von gamma-chlorallylverbindungen aus polychloralkanen

Also Published As

Publication number Publication date
DE68920757T2 (de) 1995-06-08
GR3015470T3 (en) 1995-06-30
ATE117549T1 (de) 1995-02-15
PT89839A (pt) 1989-10-04
EP0330218A3 (de) 1992-01-02
FI890827A0 (fi) 1989-02-21
KR890012641A (ko) 1989-09-18
IL89388A (en) 1995-03-15
AU618076B2 (en) 1991-12-12
DK89489A (da) 1989-08-26
AU3016089A (en) 1989-08-31
PT89839B (pt) 1994-04-29
IE65553B1 (en) 1995-11-01
ES2070134T3 (es) 1995-06-01
EP0330218A2 (de) 1989-08-30
NZ228068A (en) 1991-11-26
JP2772660B2 (ja) 1998-07-02
DK89489D0 (da) 1989-02-24
EP0330218B1 (de) 1995-01-25
FI890827A7 (fi) 1989-08-26
IE890612L (en) 1989-08-25
JPH023626A (ja) 1990-01-09
CN1035497A (zh) 1989-09-13
DE68920757D1 (de) 1995-03-09
CA1338647C (en) 1996-10-15
NO890801D0 (no) 1989-02-24

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