NO912071L - Fremgangsmaater for fremstilling av anti-tumorforbindelser - Google Patents

Fremgangsmaater for fremstilling av anti-tumorforbindelser

Info

Publication number
NO912071L
NO912071L NO91912071A NO912071A NO912071L NO 912071 L NO912071 L NO 912071L NO 91912071 A NO91912071 A NO 91912071A NO 912071 A NO912071 A NO 912071A NO 912071 L NO912071 L NO 912071L
Authority
NO
Norway
Prior art keywords
alkyl
carbon atoms
hydrogen
pharmaceutically acceptable
formula
Prior art date
Application number
NO91912071A
Other languages
English (en)
Norwegian (no)
Other versions
NO912071D0 (no
Inventor
Robert George Andrew
Andrew John Barker
Francis Thomas Boyle
James Michael Wardleworth
Original Assignee
Ici Plc
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10676728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO912071(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ici Plc, Nat Res Dev filed Critical Ici Plc
Publication of NO912071D0 publication Critical patent/NO912071D0/no
Publication of NO912071L publication Critical patent/NO912071L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO91912071A 1990-05-30 1991-05-29 Fremgangsmaater for fremstilling av anti-tumorforbindelser NO912071L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9011989 1990-05-30

Publications (2)

Publication Number Publication Date
NO912071D0 NO912071D0 (no) 1991-05-29
NO912071L true NO912071L (no) 1991-12-02

Family

ID=10676728

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91912071A NO912071L (no) 1990-05-30 1991-05-29 Fremgangsmaater for fremstilling av anti-tumorforbindelser

Country Status (15)

Country Link
US (1) US5280027A (cs)
EP (1) EP0459730A3 (cs)
JP (1) JPH04235173A (cs)
AU (1) AU640016B2 (cs)
CA (1) CA2042922A1 (cs)
CS (1) CS160591A3 (cs)
FI (1) FI912600A7 (cs)
GB (1) GB2244708B (cs)
HU (1) HUT57739A (cs)
IE (1) IE64085B1 (cs)
IL (1) IL98167A0 (cs)
NO (1) NO912071L (cs)
NZ (1) NZ238259A (cs)
PT (1) PT97799A (cs)
ZA (1) ZA913730B (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
GB9220571D0 (en) * 1992-09-30 1992-11-11 Ici Plc Quinazoline derivatives
US6174887B1 (en) 1995-08-22 2001-01-16 Japan Tobacco Inc. Amide compounds and use of the same
US5786358A (en) * 1995-09-08 1998-07-28 The Trustees Of Princeton University Pyridopyrimidines as nonclassical antifolates
GB9904275D0 (en) * 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US6518292B1 (en) * 1999-03-12 2003-02-11 Bristol-Myers Squibb Co. Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7230000B1 (en) * 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
AU2002346471A1 (en) * 2001-11-20 2003-06-10 Cytokinetics, Inc. Process for the racemization of chiral quinazolinones
AU2003213092A1 (en) * 2002-02-15 2003-09-09 Smithkline Beecham Corporation Syntheses of quinazolinones
US7214800B2 (en) * 2002-05-09 2007-05-08 Cytokinetics, Inc. Compounds, compositions, and methods
WO2003094839A2 (en) * 2002-05-09 2003-11-20 Cytokinetics, Inc. Pyrimidinone compounds, compositions and methods
AU2003265242A1 (en) * 2002-05-23 2003-12-22 Cytokinetics, Inc. Compounds, compositions, and methods
WO2003106426A1 (en) * 2002-06-14 2003-12-24 Cytokinetics, Inc. Compounds, compositions, and methods
WO2004009036A2 (en) * 2002-07-23 2004-01-29 Cytokinetics, Inc. Compounds compositions and methods
AU2003262747A1 (en) * 2002-08-21 2004-03-11 Cytokinetics, Inc. Compounds, compositions, and methods
US7557115B2 (en) 2002-09-30 2009-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
WO2005041888A2 (en) * 2003-11-03 2005-05-12 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions and methods
JP2007510660A (ja) * 2003-11-07 2007-04-26 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
US7439254B2 (en) * 2003-12-08 2008-10-21 Cytokinetics, Inc. Compounds, compositions, and methods
MX2009013815A (es) * 2007-06-22 2010-03-01 Arqule Inc Compuestos de quinazolinona y metodos de uso para los mismos.
DE102010001064A1 (de) * 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
CN103906733A (zh) 2011-06-24 2014-07-02 安姆根有限公司 Trpm8拮抗剂及其在治疗中的用途
WO2012177896A1 (en) 2011-06-24 2012-12-27 Amgen Inc. Trpm8 antagonists and their use in treatments
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
US10413583B2 (en) * 2016-11-30 2019-09-17 The University Of Chicago Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods
AU2024277518A1 (en) * 2023-05-25 2025-11-27 Allorion Therapeutics Inc N-(1h-indol-2-yl)methyl)-4-ethynyl-picolinamide derivatives as egfr inhibitors for the treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2065653B (en) * 1979-12-19 1983-03-09 Nat Res Dev Anti-cancer quinazoline derivatives
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds

Also Published As

Publication number Publication date
GB9111656D0 (en) 1991-07-24
IE911757A1 (en) 1991-12-04
US5280027A (en) 1994-01-18
FI912600A0 (fi) 1991-05-30
GB2244708A (en) 1991-12-11
IL98167A0 (en) 1992-06-21
IE64085B1 (en) 1995-07-12
NZ238259A (en) 1993-07-27
EP0459730A2 (en) 1991-12-04
CA2042922A1 (en) 1991-12-01
ZA913730B (en) 1992-02-26
NO912071D0 (no) 1991-05-29
JPH04235173A (ja) 1992-08-24
CS160591A3 (en) 1992-01-15
GB2244708B (en) 1993-12-08
FI912600A7 (fi) 1991-12-01
AU640016B2 (en) 1993-08-12
HUT57739A (en) 1991-12-30
PT97799A (pt) 1992-02-28
AU7707591A (en) 1991-12-05
EP0459730A3 (en) 1993-01-20

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