NO920125L - Fremgangsmaate for aa bestemme den funksjonelle aktivitetentil fritt protein s eller protein c i en plasmaproeve - Google Patents

Fremgangsmaate for aa bestemme den funksjonelle aktivitetentil fritt protein s eller protein c i en plasmaproeve

Info

Publication number
NO920125L
NO920125L NO92920125A NO920125A NO920125L NO 920125 L NO920125 L NO 920125L NO 92920125 A NO92920125 A NO 92920125A NO 920125 A NO920125 A NO 920125A NO 920125 L NO920125 L NO 920125L
Authority
NO
Norway
Prior art keywords
protein
tent
procedure
functional activity
pct
Prior art date
Application number
NO92920125A
Other languages
English (en)
Norwegian (no)
Other versions
NO920125D0 (no
Inventor
Steffen Rosen
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of NO920125D0 publication Critical patent/NO920125D0/no
Publication of NO920125L publication Critical patent/NO920125L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G01N2333/462—Snake venom from Agkistrodon sp., e.g. acutase, ACTE
    • G01N2333/4626—Snake venom from Agkistrodon sp., e.g. acutase, ACTE from Agkistrodon contortrix contortrix (copperhead snake); Protac (R)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/9645—Factor IX (3.4.21.22)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96461—Protein C (3.4.21.69)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NO92920125A 1989-07-14 1992-01-09 Fremgangsmaate for aa bestemme den funksjonelle aktivitetentil fritt protein s eller protein c i en plasmaproeve NO920125L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902532A SE464135B (sv) 1989-07-14 1989-07-14 Foerfarande foer bestaemning av funktionell aktivitet av fritt protein s eller protein c i ett plasmaprov
PCT/SE1990/000478 WO1991001382A1 (en) 1989-07-14 1990-07-04 A method for determining the functional activity of free protein s or protein c in a plasma sample

Publications (2)

Publication Number Publication Date
NO920125D0 NO920125D0 (no) 1992-01-09
NO920125L true NO920125L (no) 1992-01-09

Family

ID=20376547

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92920125A NO920125L (no) 1989-07-14 1992-01-09 Fremgangsmaate for aa bestemme den funksjonelle aktivitetentil fritt protein s eller protein c i en plasmaproeve

Country Status (13)

Country Link
US (1) US5439802A (de)
EP (1) EP0486515B1 (de)
JP (1) JP2892828B2 (de)
AT (1) ATE127853T1 (de)
AU (1) AU6053390A (de)
CA (1) CA2063564A1 (de)
DE (1) DE69022425T2 (de)
DK (1) DK0486515T3 (de)
ES (1) ES2079481T3 (de)
IE (1) IE902431A1 (de)
NO (1) NO920125L (de)
SE (1) SE464135B (de)
WO (1) WO1991001382A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4006634A1 (de) * 1990-03-03 1991-09-05 Behringwerke Ag Funktioneller test zur bestimmung der protein s-aktivitaet
US5716795A (en) * 1991-10-04 1998-02-10 Matschiner; John T. Thrombomodulin-based coagulometric assay of the protein C system
WO1993007491A1 (en) * 1991-10-04 1993-04-15 Board Of Regents Of The University Of Nebraska A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins
AU663343B2 (en) * 1991-10-04 1995-10-05 Dade Behring Inc. Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids
CA2119761C (en) * 1991-11-13 1997-12-16 Bjorn Dahlback Method for the diagnosis of blood coagulation disorders
SE470274B (sv) * 1991-11-13 1993-12-20 Bjoern Dahlbaeck Användning av en in vitro-metod för diagnos av blodkoagulationssjukdomar
US5308756A (en) * 1991-11-20 1994-05-03 Baxter Diagnostics Inc. Protein S chromogenic assay
DE4229933A1 (de) * 1992-09-08 1994-03-10 Max Planck Gesellschaft Verfahren zur Bestimmung von Thrombose verursachenden Lupus-anticoagulant-Antikörpern
DK0690991T4 (da) * 1993-01-29 2004-02-16 T A C Thrombosis And Coagulati Ny antikoagulant-cofaktor-aktivitet
CA2137041C (en) * 1993-12-03 2003-06-10 Katalin Varadi Assay for determining sensitivity to activated protein c
AUPM731394A0 (en) * 1994-08-05 1994-09-01 Life Therapeutics Limited Improved activated protein c resistance test
DE4427785A1 (de) * 1994-08-08 1996-02-15 Behringwerke Ag Verfahren zum Nachweis von Störungen des Protein C/Protein S-Systems
SE9403833D0 (sv) * 1994-11-08 1994-11-08 Global Hemostasis Inst Mgr Ab Analysförfarande och kit
US5780255A (en) * 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test
US5766869A (en) * 1995-11-30 1998-06-16 Ahs Hospital Corp. Factor V ratio blood test for susceptibility to thromboembolism
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
SE9701228D0 (sv) * 1997-04-03 1997-04-03 Bjoern Dahlbaeck Rekombinanta protein-C-och protein-S-varianter
AUPP159698A0 (en) * 1998-02-02 1998-02-26 Life Therapeutics Limited Improved blood coagulation test
PT947585E (pt) 1998-03-19 2001-11-30 Instrumentation Lab Spa Metodo in vitro melhorado, kits e reagentes para a peaquisa de defeitos de coagulacao sanguinea
US6855509B2 (en) 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
RU2270020C2 (ru) * 2004-04-20 2006-02-20 Государственное учреждение Кировский научно-исследовательский институт гематологии и переливания крови (ГУ Книги ПК) Способ получения контрольной плазмы с нормальным уровнем протромбинового комплекса
JP5839256B2 (ja) 2011-03-14 2016-01-06 学校法人九州文化学園 総プロテインｓ異常症の検出方法において用いる試薬
CN106153612A (zh) * 2015-12-04 2016-11-23 上海贞元诊断用品科技有限公司 抗凝血酶活性检测试剂及其制备方法和应用
CN120761656A (zh) * 2025-09-03 2025-10-10 湖南赛新生物科技有限公司 一种高稳定性蛋白s活性测定试剂盒及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
DE3516579A1 (de) * 1984-11-19 1986-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Gerinnungstest auf teststreifen
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
DE3607559A1 (de) * 1986-03-07 1987-09-10 Boehringer Mannheim Gmbh Verfahren zur photometrischen bestimmung der protein c- und/oder protein s-aktivitaet
US4908314A (en) * 1987-07-02 1990-03-13 American National Red Cross Protein C activator
DE3724443A1 (de) * 1987-07-23 1989-02-02 Max Planck Gesellschaft Funktioneller test zur bestimmung der protein s-aktivitaet
JP2739050B2 (ja) * 1988-01-28 1998-04-08 ヘキスト薬品工業株式会社 抗血液凝固剤
US5051357A (en) * 1989-07-14 1991-09-24 Board Of Trustees Operating Michigan State University Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor

Also Published As

Publication number Publication date
NO920125D0 (no) 1992-01-09
DK0486515T3 (da) 1996-01-29
SE464135B (sv) 1991-03-11
ATE127853T1 (de) 1995-09-15
US5439802A (en) 1995-08-08
JPH04506603A (ja) 1992-11-19
SE8902532L (sv) 1991-01-15
CA2063564A1 (en) 1991-01-15
AU6053390A (en) 1991-02-22
JP2892828B2 (ja) 1999-05-17
DE69022425T2 (de) 1996-05-02
EP0486515B1 (de) 1995-09-13
ES2079481T3 (es) 1996-01-16
EP0486515A1 (de) 1992-05-27
IE902431A1 (en) 1991-06-19
WO1991001382A1 (en) 1991-02-07
DE69022425D1 (de) 1995-10-19
SE8902532D0 (sv) 1989-07-14

Similar Documents

Publication Publication Date Title
NO920125L (no) Fremgangsmaate for aa bestemme den funksjonelle aktivitetentil fritt protein s eller protein c i en plasmaproeve
ATE247173T1 (de) Charakterisierung von polypeptiden
WO1995021601A3 (en) Kallikrein-inhibiting 'kunitz domain' proteins and analogues thereof
DK0756638T3 (da) Midler til behandling af forstyrrelser i blodkoagulationskaskaden
TR200001709T2 (tr) Yeni neisseria meningitids yüzey proteini
WO1998033509A3 (en) Useful properties of human lactoferrin and variants thereof
DE69932845D1 (de) Methoden zur quantifizierung von hla-dr und cd11b
ATE196147T1 (de) Wachstumsdifferenzierungsfaktor-12
NO953770L (no) Analysemetode
SE9403833D0 (sv) Analysförfarande och kit
DK0687180T3 (da) Fremgangsmåde til påvisning og behandling af individer, som har unormale celler, som udtrykker HLC-A2/tyrosinasepeptid-anti
EP1132402A4 (de) Peptidfragmente mit den zelltod verhindernden aktivität
DE60120374D1 (de) Methoden zur reinigung von stark anionischen proteinen
SE8501614L (sv) Solubiliserbar, fibrinbaserad komposition och anvendning derav
ES548529A0 (es) Procedimiento de modificacion de celulas eucariotas.
DK0791073T3 (da) Analysemetode
EA199800352A1 (ru) ПОЛИПЕПТИД ХЕМОКИНА β-8 (ВАРИАНТЫ) И СПОСОБ ЕГО ПОЛУЧЕНИЯ, КОМПОЗИЦИИ ПОЛИПЕПТИДОВ, ВЕКТОР, КЛЕТКА-ХОЗЯИН, АГОНИСТ И АНТАГОНИСТ, ВСЕ - УПОМЯНУТОГО ПОЛИПЕПТИДА, И СПОСОБ ИДЕНТИФИКАЦИИ ПОСЛЕДНЕГО, СПОСОБ ЛЕЧЕНИЯ БОЛЬНОГО, ИСПЫТЫВАЮЩЕГО ПОТРЕБНОСТЬ В Хк-β-8 (ВАРИАНТЫ), СПОСОБ ЛЕЧЕНИЯ БОЛЬНОГО, ИСПЫТЫВАЮЩЕГО ПОТРЕБНОСТЬ В ПОДАВЛЕНИИ Хк-β-8, СПОСОБ ДИАГНОСТИКИ ЗАБОЛЕВАНИЯ ИЛИ ПРЕДРАСПОЛОЖЕННОСТИ К ЗАБОЛЕВАНИЮ, ОБУСЛОВЛЕННОМУ НЕДОСТАТОЧНОЙ ЭКСПРЕССИЕЙ ПОЛИПЕПТИДА
DE69636041D1 (de) Nachweis von brusttumorvirus-artigen sequenzen in brustkrebs bei menschen
ATE312179T1 (de) Serin-threonin-kinase enthaltendes mittel zur tumortherapie und tumordiagnose
ATE390440T1 (de) Neuroaktive peptide
ATE242883T1 (de) Verfahren zur bestimmung von blutgerinnungsfaktoren viii und ix
ATE267253T1 (de) Von htlv-i und htlv-ii gp21 abgeleitete peptide zur diagnostischen verwendung
ATE243320T1 (de) Diagnostische verfahren und zusammensetzungen auf basis der verteilung von rad51
DE59708783D1 (de) Diagnosehilfe sowie verfahren zum nachweis der trächtigkeit von wiederkäuern
Jaiswala et al. Sperm capacitation is, after all, a prerequisite for both partial and complete acrosome reaction