NO922358L - Tert.-butylfenyl-1-amino-4-hydroksybutanderivater, fremgangsmaate ved deres fremstilling og farmasoeytiske preparaterinneholdende forbindelsene - Google Patents

Tert.-butylfenyl-1-amino-4-hydroksybutanderivater, fremgangsmaate ved deres fremstilling og farmasoeytiske preparaterinneholdende forbindelsene

Info

Publication number: NO922358L
Authority: NO; Norway
Prior art keywords: compounds; preparation; butylphenyl; tert; procedures
Prior art date: 1990-10-17

Application number

NO92922358A

Other languages

English (en)

Norwegian (no)

Other versions

NO922358D0 (no

Inventor

Paule Bonnet

Remi Delansorne

Maurice Faure

Michel Lanquetin

Serge Zunino

Original Assignee

Theramex

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-17

Filing date

1992-06-16

Publication date

1992-08-11

1992-06-16 Application filed by Theramex filed Critical Theramex

1992-06-16 Publication of NO922358D0 publication Critical patent/NO922358D0/no

1992-08-11 Publication of NO922358L publication Critical patent/NO922358L/no

Links

150000001875 compounds Chemical class 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 2
-1 4-substituted-phenyl Chemical group 0.000 abstract 1
LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical group O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
150000007522 mineralic acids Chemical class 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
150000007524 organic acids Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

NO92922358A 1990-10-17 1992-06-16 Tert.-butylfenyl-1-amino-4-hydroksybutanderivater, fremgangsmaate ved deres fremstilling og farmasoeytiske preparaterinneholdende forbindelsene NO922358L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR909012562A FR2668150B1 (fr)	1990-10-17	1990-10-17	Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
PCT/FR1991/000811 WO1992006977A1 (fr)	1990-10-17	1991-10-17	NOUVEAUX DERIVES p-SUBSTITUES DE PHENYL 4-OXYBUTANE AMINE, LEURS PROCEDES DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES EN RENFERMANT

Publications (2)

Publication Number	Publication Date
NO922358D0 NO922358D0 (no)	1992-06-16
NO922358L true NO922358L (no)	1992-08-11

Family

ID=9401134

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO92922358A NO922358L (no)	1990-10-17	1992-06-16	Tert.-butylfenyl-1-amino-4-hydroksybutanderivater, fremgangsmaate ved deres fremstilling og farmasoeytiske preparaterinneholdende forbindelsene

Country Status (23)

Country	Link
US (1)	US5461059A (fr)
EP (1)	EP0505543A1 (fr)
JP (1)	JPH05503298A (fr)
KR (1)	KR927003589A (fr)
AP (1)	AP282A (fr)
BG (1)	BG60680B1 (fr)
BR (1)	BR9106188A (fr)
CA (1)	CA2071911A1 (fr)
CZ (1)	CZ182292A3 (fr)
FI (1)	FI922773L (fr)
FR (2)	FR2668150B1 (fr)
HU (1)	HUT61297A (fr)
IE (1)	IE913636A1 (fr)
IL (1)	IL99776A0 (fr)
MA (1)	MA22321A1 (fr)
NO (1)	NO922358L (fr)
NZ (1)	NZ240274A (fr)
OA (1)	OA09835A (fr)
PL (2)	PL169452B1 (fr)
PT (1)	PT99266A (fr)
RO (1)	RO108241B1 (fr)
WO (1)	WO1992006977A1 (fr)
ZA (1)	ZA918282B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2048109B1 (es) *	1992-07-20	1994-12-16	Espanola Prod Quimicos	Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
CA2161876A1 (fr) *	1993-05-20	1994-12-08	Den-Ichi Momose	Composes de type 1-(2-benzimidazolyl)-1,5-diazacyclooctane
ES2072193B1 (es) *	1993-05-21	1996-02-16	Espanola Prod Quimicos	Nuevos derivados del1-fenilmetil bencimidazol piperacinas.
US5691323A (en) *	1995-05-12	1997-11-25	Merck & Co., Inc.	Muscarine antagonists
FR2727865B1 (fr) *	1994-12-08	1997-07-18	Esteve Labor Dr	Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
WO1997036592A1 (fr) *	1996-04-03	1997-10-09	Merck & Co., Inc.	Inhibiteurs de farnesyle-proteine transferase
MXPA02012272A (es) *	2000-07-04	2003-04-25	Novo Nordisk As	Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv.
WO2004009091A1 (fr) *	2002-06-17	2004-01-29	Glaxo Group Limited	Agonistes des recepteurs x du foie

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL297097A (fr) *	1962-08-31
US3161645A (en) *	1962-12-18	1964-12-15	Res Lab Dr C Janssen N V	1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
US3491103A (en) *	1963-12-19	1970-01-20	Sandoz Ag	Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
JPS5879983A (ja) *	1981-11-06	1983-05-13	Kanebo Ltd	新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
NZ223654A (en) *	1987-03-09	1990-03-27	Janssen Pharmaceutica Nv	1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
MY106964A (en) *	1988-04-28	1995-08-30	Schering Corp	Fused polycyclic compounds, compositions, methods of manufacture, and their use as paf antagonists, antihistamines and/or antiinflammatory agents.
US4908372A (en) *	1988-10-13	1990-03-13	Merrell Dow Pharmaceuticals Inc.	Antihistaminic piperidinyl benzimidazoles
PH30434A (en) *	1989-04-07	1997-05-09	Janssen Pharmaceutica Nv	Hydroxyalkylfuranyl derivatives
US5217980A (en) *	1990-07-19	1993-06-08	Janssen Pharmaceutica N.V.	Oxazolyl and piperidinyl substituted benimidazolyl compounds

1990
- 1990-10-17 FR FR909012562A patent/FR2668150B1/fr not_active Expired - Fee Related
1991
- 1991-10-11 FR FR919112515A patent/FR2670783B1/fr not_active Expired - Fee Related
- 1991-10-16 MA MA22603A patent/MA22321A1/fr unknown
- 1991-10-17 KR KR1019920701452A patent/KR927003589A/ko not_active Ceased
- 1991-10-17 BR BR919106188A patent/BR9106188A/pt not_active Application Discontinuation
- 1991-10-17 EP EP91918443A patent/EP0505543A1/fr not_active Withdrawn
- 1991-10-17 ZA ZA918282A patent/ZA918282B/xx unknown
- 1991-10-17 PL PL91310562A patent/PL169452B1/pl unknown
- 1991-10-17 CA CA002071911A patent/CA2071911A1/fr not_active Abandoned
- 1991-10-17 HU HU922176A patent/HUT61297A/hu unknown
- 1991-10-17 AP APAP/P/1991/000328A patent/AP282A/en active
- 1991-10-17 PL PL91295029A patent/PL169022B1/pl unknown
- 1991-10-17 JP JP3517705A patent/JPH05503298A/ja active Pending
- 1991-10-17 WO PCT/FR1991/000811 patent/WO1992006977A1/fr not_active Ceased
- 1991-10-17 IL IL99776A patent/IL99776A0/xx unknown
- 1991-10-17 PT PT99266A patent/PT99266A/pt not_active Application Discontinuation
- 1991-10-17 FI FI922773A patent/FI922773L/fi not_active Application Discontinuation
- 1991-10-17 NZ NZ240274A patent/NZ240274A/en unknown
- 1991-10-17 RO RO92-0818A patent/RO108241B1/ro unknown
- 1991-10-17 IE IE363691A patent/IE913636A1/en not_active Application Discontinuation
- 1991-10-17 US US07/861,816 patent/US5461059A/en not_active Expired - Fee Related
1992
- 1992-06-15 CZ CS921822A patent/CZ182292A3/cs unknown
- 1992-06-16 BG BG96487A patent/BG60680B1/bg unknown
- 1992-06-16 NO NO92922358A patent/NO922358L/no unknown
- 1992-06-17 OA OA60229A patent/OA09835A/fr unknown

Also Published As

Publication number	Publication date
EP0505543A1 (fr)	1992-09-30
KR927003589A (ko)	1992-12-18
FR2670783B1 (fr)	1994-11-18
HU9202176D0 (en)	1992-10-28
FR2668150B1 (fr)	1994-11-18
FI922773A7 (fi)	1992-06-16
PL169452B1 (pl)	1996-07-31
CZ182292A3 (en)	1993-01-13
MA22321A1 (fr)	1992-07-01
AP9100328A0 (en)	1991-10-31
BG60680B1 (bg)	1995-12-29
NZ240274A (en)	1995-07-26
PT99266A (pt)	1992-08-31
FI922773A0 (fi)	1992-06-16
ZA918282B (en)	1992-07-29
NO922358D0 (no)	1992-06-16
US5461059A (en)	1995-10-24
BR9106188A (pt)	1993-03-16
PL169022B1 (pl)	1996-05-31
JPH05503298A (ja)	1993-06-03
WO1992006977A1 (fr)	1992-04-30
RO108241B1 (ro)	1994-03-31
HUT61297A (en)	1992-12-28
AP282A (en)	1993-09-08
BG96487A (bg)	1993-12-24
IL99776A0 (en)	1992-08-18
IE913636A1 (en)	1992-04-22
CA2071911A1 (fr)	1992-04-18
FI922773L (fi)	1992-06-16
OA09835A (fr)	1994-08-15
FR2670783A1 (fr)	1992-06-26
FR2668150A1 (fr)	1992-04-24

Publication	Publication Date	Title
DE68925223D1 (de)	1996-02-08	3-Alkenyl-1-azabicyclo(3.2.0)hept-2-en-2-carbonsäure-Verbindungen
ATE79376T1 (de)	1992-08-15	Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DK0457686T3 (da)	1994-12-12	Hidtil ukendte aminopiperidin-, aminopyrrolidin- og aminoperhydroazepinderivater, fremgangsmåder til fremstilling heraf og farmaceutiske midler, som indeholder dem
LU91362I2 (fr)	2007-11-12	Palipéridone et ses dérivés pharmaceutiquement acceptables (INVEGA)
ES2057016T3 (es)	1994-10-16	Compuestos de acido 3-pirrolidiniltio-1-azabiciclo (3.2.0) hept-2-eno-2-carboxilico.
ATE107306T1 (de)	1994-07-15	3-pyrrolidinylthio-1-azabicyclo (3.2.0)hept-2-en- 2-carbonsäure-verbindungen.
NO20001169L (no)	2000-04-05	6,9-bro erythromycinderivater
ES2011427A4 (es)	1990-01-16	Derivados de oxina de octahidronaftaleno para inhibicion de la sintesis del colesterol, procesos para su preparacion y composiciones que los contienen.
NO167803C (no)	1991-12-11	Analogifremgangsmaate til fremstilling av terapeutiskordskilleaktive n-(4-piperidinyl)bicyklisk kondenserte 2-imidazolaminderivater.
NO963655L (no)	1996-11-01	Nye aminosyrederivater, fremgangsmåte for fremstilling av dem og farmasöytiske blandinger som inneholder dem
FR2672213B1 (fr)	1995-03-10	Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.
FI872930A0 (fi)	1987-07-02	Analogiamenetelmä ripulinvastaisten 4-(bentsoyyliamino)piperidiinibutaaniamidijohdannaisten valmistamiseksi
BG96487A (bg)	1993-12-24	Р-заместени производни на 4-оксибутанамина,методи за получаването им и тяхното приложение
EP0123962A3 (en)	1987-10-07	Novel benzimidazole derivative, process for the preparation thereof and pharmaceutical composition
NO180443C (no)	1997-04-23	Oktahydronaftalenoksimderivater samt farmasöytiske preparater som omfatter et slikt derivat til inhibering av kolesterolbiosyntese
FI853866A0 (fi)	1985-10-04	2-pyridin-tiol-derivat, foerfarande foer framstaellning av dessa samt farmaceutiska foereningar innehaollande dessa.
DK360388A (da)	1989-01-02	Laegemiddel til behandling af hjerteinsufficiens
NO942181L (fr)	1994-06-10
NO934881L (no)	1994-07-01	Benzotiazolderivater, fremgangsmåte for deres fremstilling og farmasöytisk preparat derav
DK198282A (da)	1982-11-05	Penicillin- eller cephalosporinderivater, deres fremstilling og anvendelse som farmaceutika