NO930594L - Nye arylkarbonylaminoalkyl-dihydro-okso-pyridiner, deres fremstilling og anvendelse - Google Patents
Nye arylkarbonylaminoalkyl-dihydro-okso-pyridiner, deres fremstilling og anvendelseInfo
- Publication number
- NO930594L NO930594L NO93930594A NO930594A NO930594L NO 930594 L NO930594 L NO 930594L NO 93930594 A NO93930594 A NO 93930594A NO 930594 A NO930594 A NO 930594A NO 930594 L NO930594 L NO 930594L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- disturbances
- hydrogen
- compounds
- arylcarbonylaminoalkyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 230000017531 blood circulation Effects 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010004663 Biliary colic Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 abstract 1
- 206010036600 Premature labour Diseases 0.000 abstract 1
- 206010038419 Renal colic Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 210000003445 biliary tract Anatomy 0.000 abstract 1
- 210000000621 bronchi Anatomy 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000003779 hair growth Effects 0.000 abstract 1
- 230000003676 hair loss Effects 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 230000008991 intestinal motility Effects 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
- 230000035935 pregnancy Effects 0.000 abstract 1
- 208000026440 premature labor Diseases 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 210000000626 ureter Anatomy 0.000 abstract 1
- 210000003708 urethra Anatomy 0.000 abstract 1
- 210000003932 urinary bladder Anatomy 0.000 abstract 1
- 210000001635 urinary tract Anatomy 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92102828 | 1992-02-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO930594D0 NO930594D0 (no) | 1993-02-19 |
| NO930594L true NO930594L (no) | 1993-08-23 |
Family
ID=8209352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO93930594A NO930594L (no) | 1992-02-20 | 1993-02-19 | Nye arylkarbonylaminoalkyl-dihydro-okso-pyridiner, deres fremstilling og anvendelse |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5360808A (de) |
| EP (1) | EP0556738B1 (de) |
| JP (1) | JPH069560A (de) |
| KR (1) | KR930017895A (de) |
| CN (1) | CN1075480A (de) |
| AT (1) | ATE122659T1 (de) |
| AU (1) | AU3375993A (de) |
| CA (1) | CA2089955A1 (de) |
| CZ (1) | CZ403592A3 (de) |
| DE (1) | DE69300152D1 (de) |
| FI (1) | FI930716L (de) |
| HU (1) | HU9300463D0 (de) |
| IL (1) | IL104781A0 (de) |
| MA (1) | MA22806A1 (de) |
| MX (1) | MX9300915A (de) |
| NO (1) | NO930594L (de) |
| ZA (1) | ZA931185B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020052295A1 (en) * | 1999-12-21 | 2002-05-02 | Hegde Shridhar G. | Diacyl derivatives of propylene diamine having herbicidal activity |
| DE10205219A1 (de) * | 2002-02-08 | 2003-08-21 | Bayer Ag | Chinoxalinone und ihre Verwendung |
| US6869966B2 (en) * | 2002-09-30 | 2005-03-22 | Banyu Pharmaceutical Co., Ltd. | N-substituted-2-oxodihydropyridine derivatives |
| US20040127129A1 (en) * | 2002-12-31 | 2004-07-01 | Shuiyuan Luo | Grooved-shape monofilaments and the fabrics made thereof |
| US8138209B2 (en) * | 2005-07-13 | 2012-03-20 | Jenrin Discovery, Inc. | Substituted picolinamides as MAO-B inhibitors useful for treating obesity |
| US8314087B2 (en) | 2007-02-16 | 2012-11-20 | Amgen Inc. | Nitrogen-containing heterocyclyl ketones and methods of use |
| EP2393781B1 (de) | 2008-12-23 | 2014-03-12 | F. Hoffmann-La Roche AG | Dihydropyridonharnstoffe als p2x7-modulatoren |
| BRPI0923488A2 (pt) | 2008-12-23 | 2019-09-24 | Hoffmann La Roche | amidas de didropiridona como modulares p2x7 |
| US8153808B2 (en) | 2008-12-23 | 2012-04-10 | Roche Palo Alto Llc | Dihydropyridone amides as P2X7 modulators |
| JP5478637B2 (ja) | 2008-12-23 | 2014-04-23 | エフ.ホフマン−ラ ロシュ アーゲー | P2x7モジュレーターとしてのジヒドロピリドンアミド |
| CA2745952A1 (en) | 2008-12-23 | 2010-07-01 | F.Hoffmann-La Roche Ag | Dihydropyridone amides as p2x7 modulators |
| US8816085B2 (en) | 2009-08-26 | 2014-08-26 | Takeda Gmbh | Methylpyrrolopyridinecarboxamides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2637477A1 (de) * | 1976-08-20 | 1978-02-23 | Hoechst Ag | Dihydro-oxo-nicotinsaeuren und verfahren zu ihrer herstellung |
| IL61501A (en) * | 1979-11-26 | 1984-06-29 | Sterling Drug Inc | 5-(pyridinyl)-2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| US4297360A (en) * | 1980-03-28 | 1981-10-27 | Sterling Drug Inc. | 5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use |
| IT8367883A0 (it) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche |
| GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
-
1992
- 1992-12-31 CZ CS924035A patent/CZ403592A3/cs unknown
-
1993
- 1993-02-12 EP EP93102220A patent/EP0556738B1/de not_active Expired - Lifetime
- 1993-02-12 DE DE69300152T patent/DE69300152D1/de not_active Expired - Lifetime
- 1993-02-12 AT AT93102220T patent/ATE122659T1/de not_active IP Right Cessation
- 1993-02-18 FI FI930716A patent/FI930716L/fi not_active Application Discontinuation
- 1993-02-18 KR KR1019930002218A patent/KR930017895A/ko not_active Withdrawn
- 1993-02-18 IL IL104781A patent/IL104781A0/xx unknown
- 1993-02-18 US US08/019,296 patent/US5360808A/en not_active Expired - Fee Related
- 1993-02-19 NO NO93930594A patent/NO930594L/no unknown
- 1993-02-19 CA CA002089955A patent/CA2089955A1/en not_active Abandoned
- 1993-02-19 ZA ZA931185A patent/ZA931185B/xx unknown
- 1993-02-19 HU HU9300463A patent/HU9300463D0/hu unknown
- 1993-02-19 AU AU33759/93A patent/AU3375993A/en not_active Abandoned
- 1993-02-19 MX MX9300915A patent/MX9300915A/es unknown
- 1993-02-19 JP JP5029515A patent/JPH069560A/ja active Pending
- 1993-02-19 MA MA23099A patent/MA22806A1/fr unknown
- 1993-02-19 CN CN93101816A patent/CN1075480A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MA22806A1 (fr) | 1993-10-01 |
| FI930716A0 (fi) | 1993-02-18 |
| US5360808A (en) | 1994-11-01 |
| AU3375993A (en) | 1993-08-26 |
| IL104781A0 (en) | 1993-06-10 |
| FI930716A7 (fi) | 1993-08-21 |
| EP0556738A1 (de) | 1993-08-25 |
| HU9300463D0 (en) | 1993-05-28 |
| NO930594D0 (no) | 1993-02-19 |
| ZA931185B (en) | 1993-09-16 |
| CN1075480A (zh) | 1993-08-25 |
| CA2089955A1 (en) | 1993-08-21 |
| MX9300915A (es) | 1993-09-01 |
| CZ403592A3 (en) | 1993-12-15 |
| DE69300152D1 (de) | 1995-06-22 |
| EP0556738B1 (de) | 1995-05-17 |
| ATE122659T1 (de) | 1995-06-15 |
| JPH069560A (ja) | 1994-01-18 |
| KR930017895A (ko) | 1993-09-20 |
| FI930716L (fi) | 1993-08-21 |
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