NO941550D0 - - Google Patents

Info

Publication number
NO941550D0
NO941550D0 NO941550A NO941550A NO941550D0 NO 941550 D0 NO941550 D0 NO 941550D0 NO 941550 A NO941550 A NO 941550A NO 941550 A NO941550 A NO 941550A NO 941550 D0 NO941550 D0 NO 941550D0
Authority
NO
Norway
Prior art keywords
subjecting
esters
fatty acids
eicosapentaenoic acid
fraction
Prior art date
Application number
NO941550A
Other languages
English (en)
Norwegian (no)
Other versions
NO941550L (fr
NO302038B1 (no
Original Assignee
Nippon Suisan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Suisan Kaisha Ltd filed Critical Nippon Suisan Kaisha Ltd
Publication of NO941550D0 publication Critical patent/NO941550D0/no
Publication of NO941550L publication Critical patent/NO941550L/no
Publication of NO302038B1 publication Critical patent/NO302038B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08Refining
    • C11C1/10Refining by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/43Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C07C51/44Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/52Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C07C67/54Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/56Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/10Refining fats or fatty oils by adsorption
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00Refining fats or fatty oils
    • C11B3/12Refining fats or fatty oils by distillation
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08Refining

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
NO941550A 1991-10-28 1994-04-27 Fremgangsmåte for å produsere höy-ren eikosapentaensyre eller dens ester NO302038B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28168691A JP3400466B2 (ja) 1991-10-28 1991-10-28 高純度エイコサペンタエン酸またはそのエステルの製造方法
PCT/JP1992/001393 WO1993009210A1 (fr) 1991-10-28 1992-10-28 Procede de production d'acide eicosapentaenoique de haute purete ou d'un ester de celui-ci

Publications (3)

Publication Number Publication Date
NO941550D0 true NO941550D0 (fr) 1994-04-27
NO941550L NO941550L (fr) 1994-06-27
NO302038B1 NO302038B1 (no) 1998-01-12

Family

ID=17642575

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941550A NO302038B1 (no) 1991-10-28 1994-04-27 Fremgangsmåte for å produsere höy-ren eikosapentaensyre eller dens ester

Country Status (11)

Country Link
US (1) US5840944A (fr)
EP (1) EP0610506B1 (fr)
JP (1) JP3400466B2 (fr)
AT (1) ATE181567T1 (fr)
AU (1) AU664866B2 (fr)
CA (1) CA2122345C (fr)
DE (1) DE69229480T2 (fr)
DK (1) DK0610506T3 (fr)
ES (1) ES2132133T3 (fr)
NO (1) NO302038B1 (fr)
WO (1) WO1993009210A1 (fr)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08512336A (ja) * 1993-04-29 1996-12-24 ノルスク・ヒドロ・アクシェセルスカープ 脂肪酸およびその誘導体のクロマトグラフィーによる分画方法
JP4151853B2 (ja) 1996-10-11 2008-09-17 スカリスタ リミテッド エイコサペンタエン酸および/またはステアリドン酸を含む治療用薬剤
JP2872986B1 (ja) * 1998-01-21 1999-03-24 池田食研株式会社 高純度高度不飽和脂肪酸の低級アルコールエステル精製方法
GB9901809D0 (en) 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
DE60012934T2 (de) 1999-02-26 2005-08-25 Martek Biosciences Corp. Verfahren zum Abtrennen von einem Docosahexaensäure enthaltenden Triglycerid aus einem Triglyceridgemisch
ES2159257B1 (es) * 1999-11-19 2002-04-16 Kd Iqa S L Nuevo procedimiento de preparacion del ester etilico del acido eicosa pentaenoico.
EP1125914A1 (fr) 2000-02-14 2001-08-22 Nisshin Flour Milling Co., Ltd. Procédé de séparation et de purification d'acide eicosapentaénoique ou d'un ester de celui-ci
FR2833006A1 (fr) * 2001-11-30 2003-06-06 Cognis France Sa Procede de preparation d'ester methylique d'acide oleique industriel
JP4109893B2 (ja) * 2002-04-24 2008-07-02 株式会社日本触媒 アジリジン類およびn−ビニルアミド類の製造方法
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
WO2007149577A2 (fr) * 2006-06-23 2007-12-27 The Procter & Gamble Company Acides gras oméga 3 concentrés et sans odeur
KR101357298B1 (ko) * 2008-06-20 2014-01-28 에이케이 앤 엠엔 바이오팜 주식회사 오메가-3계 고도불포화 지방산의 고순도 정제방법
EP4137128A1 (fr) 2008-09-02 2023-02-22 Amarin Pharmaceuticals Ireland Limited Composition pharmaceutique contenant de l'acide eicosapentaénoïque et leurs procédés d'utilisation
ES2768091T3 (es) 2009-02-10 2020-06-19 Amarin Pharmaceuticals Ie Ltd Uso del éster etílico del ácido eicosapentaenoico para tratar la hipertrigliceridemia
NZ720946A (en) 2009-04-29 2017-09-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
MX350088B (es) 2009-04-29 2017-08-25 Amarin Pharma Inc Composicion farmaceutica estable y metodos de uso de la misma.
CN108096209A (zh) 2009-06-15 2018-06-01 阿马里纳制药公司 在相伴他汀类疗法的对象中降低甘油三酯、没有增加ldl-c水平的组合物和方法
US20110071176A1 (en) 2009-09-23 2011-03-24 Amarin Pharma, Inc. Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
CA2873141C (fr) * 2009-12-30 2018-05-29 Adam Kelliher Procede de separation chromatographique en lit mobile simule
PH12012501755A1 (en) * 2010-03-04 2012-11-12 Amarin Pharma Inc Compositions and methods for treating and/or preventing cardiovascular disease
CA2814849A1 (fr) * 2010-10-13 2012-04-19 Cognis Ip Management Gmbh Dispositif et procede de distillation de substances sensibles a la temperature
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
NZ712068A (en) 2010-11-29 2017-03-31 Amarin Pharmaceuticals Ie Ltd Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US9119826B2 (en) 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US8951514B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
CN102391112B (zh) * 2011-10-31 2014-06-04 赵永俊 一种工业化生产二十碳五烯酸乙酯的方法
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US20130131170A1 (en) 2011-11-07 2013-05-23 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
WO2013083482A1 (fr) 2011-12-05 2013-06-13 Chromacon Ag Procédé chromatographique de séparation de mélanges d'acides gras
ES2891473T3 (es) 2012-01-06 2022-01-28 Amarin Pharmaceuticals Ie Ltd Composiciones y métodos para reducir los niveles de alta sensibilidad (hs-CRP) en un sujeto
CA3225865A1 (fr) 2012-05-14 2013-11-21 Nissui Corporation Methode de production d'acide gras tres insature ou d'ester ethylique d'acide gras tres insature presentant une reduction des polluants environnementaux
CA3067012C (fr) 2012-06-29 2021-10-05 Amarin Pharmaceuticals Ireland Limited Procedes de reduction du risque d'un evenement cardiovasculaire chez un sujet soumis a un traitement par une statine
WO2014050692A1 (fr) * 2012-09-28 2014-04-03 持田製薬株式会社 Composition pour réduire de nouvelles apparitions de diabète
WO2014074552A2 (fr) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions et procédés pour diminuer les triglycérides sans augmenter les taux de ldl-c chez un sujet traité en même temps par la statine
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP2801604B1 (fr) 2013-05-07 2017-04-12 Groupe Novasep Procédé chromatographique pour la production d'acides gras polyinsaturés hautement purifiés
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
HUE055277T2 (hu) 2013-12-04 2021-11-29 Nippon Suisan Kaisha Ltd Dihomo-gamma-linolénsavat tartalmazó mikrobális olaj és dihomo-gamma-linolénsavat tartalmazó mikrobális biomassza
EP2883860B1 (fr) * 2013-12-11 2016-08-24 Novasep Process Procédé chromatographique de production d'acides gras polyinsaturés
JP6303017B2 (ja) 2014-01-07 2018-03-28 ノヴァセプ プロセスNovasep Process 芳香族アミノ酸を精製する方法
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
CA2953319C (fr) 2014-07-02 2022-11-29 Nippon Suisan Kaisha, Ltd. Methode de production d'acides gras mono-insatures libres derives de produits de la mer ou d'esters a faible teneur en alcool de ceux-ci
CN120623044A (zh) * 2014-09-17 2025-09-12 株式会社日水 含有二十碳五烯酸烷基酯的组合物及其制造方法
HK1258568A1 (zh) * 2015-10-05 2019-11-15 Dsm Ip Assets B.V. 油组合物和制备方法
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
WO2018213663A1 (fr) 2017-05-19 2018-11-22 Amarin Pharmaceuticals Ireland Limited Compositions et méthodes pour dimunuer les triglycérides chez un sujet ayant une fonction rénale réduite
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
MA51766A (fr) 2018-09-24 2020-12-16 Amarin Pharmaceuticals Ie Ltd Procédés de réduction du risque d'événements cardiovasculaires chez un sujet
CN109438220B (zh) * 2018-10-31 2021-04-13 苏州赛分科技有限公司 一种从鱼油中纯化epa的方法
ES2915598T3 (es) 2018-12-12 2022-06-23 Nippon Suisan Kaisha Ltd Una composición que contiene un ácido graso altamente insaturado o un éster alquílico del mismo y un método para producirla
BR112022009189A2 (pt) 2019-11-12 2022-07-26 Amarin Pharmaceuticals Ie Ltd Métodos para reduzir o risco de eventos cardiovasculares em um sujeito com fibrilação atrial e/ou palpitação atrial
EP4086621B1 (fr) * 2021-03-17 2025-12-31 Nissui Corporation Procédé de purification
US11986452B2 (en) 2021-04-21 2024-05-21 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure
TW202515986A (zh) 2023-06-30 2025-04-16 日商日水股份有限公司 含有高度不飽和脂肪酸或其酯衍生物的組合物及其製造方法
CN117800839A (zh) * 2024-01-08 2024-04-02 浙江可明生物医药有限公司 一种含二十碳五烯酸乙酯的组合物及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57149400A (en) * 1981-03-12 1982-09-14 Kureha Chemical Ind Co Ltd Manufacture of high purity long chain highly unsaturated fatty acid ester
US4377526A (en) * 1981-05-15 1983-03-22 Nippon Suisan Kaisha, Ltd. Method of purifying eicosapentaenoic acid and its esters
JPS588037A (ja) * 1981-07-03 1983-01-18 Nippon Suisan Kaisha Ltd エイコサペンタエン酸またはそのエステルの製法
JPS58109444A (ja) * 1981-11-19 1983-06-29 Kureha Chem Ind Co Ltd エイコサペンタエン酸又はそのエステル、ドコサヘキサエン酸又はそのエステルの分離精製法
JPS5888339A (ja) * 1981-11-20 1983-05-26 Kagakuhin Kensa Kyokai エイコサペンタエン酸又はそのエステルとドコサヘキサエン酸又はそのエステルの分離精製方法
JPS60208940A (ja) * 1984-03-31 1985-10-21 Nippon Zeon Co Ltd 長鎮不飽和脂肪酸化合物の分離精製法
JPH0768169B2 (ja) * 1989-03-30 1995-07-26 千代田化工建設株式会社 エイコサペンタエン酸エステル及び/又はドコサヘキサエン酸エステルの分離方法
JPH02268133A (ja) * 1989-04-10 1990-11-01 Nippon Suisan Kaisha Ltd エイコサペンタエン酸またはそのエステルの製造法
CA2043615C (fr) * 1990-06-04 2001-08-14 Kazuhiko Hata Methode de preparation de l'acide icosapentenoique ou d'un ester de ce dernier
US5215630A (en) * 1991-06-04 1993-06-01 Nippon Suisan Kaisha, Ltd. Method of purifying eicosapentaenoic acid or the ester derivative thereof by fractional distillation

Also Published As

Publication number Publication date
EP0610506B1 (fr) 1999-06-23
JP3400466B2 (ja) 2003-04-28
DE69229480D1 (de) 1999-07-29
DE69229480T2 (de) 2000-02-17
AU2873992A (en) 1993-06-07
ATE181567T1 (de) 1999-07-15
EP0610506A1 (fr) 1994-08-17
NO941550L (fr) 1994-06-27
JPH05222392A (ja) 1993-08-31
AU664866B2 (en) 1995-12-07
ES2132133T3 (es) 1999-08-16
EP0610506A4 (en) 1995-12-13
CA2122345C (fr) 2004-03-09
DK0610506T3 (da) 2000-01-24
NO302038B1 (no) 1998-01-12
CA2122345A1 (fr) 1993-05-13
WO1993009210A1 (fr) 1993-05-13
US5840944A (en) 1998-11-24

Similar Documents

Publication Publication Date Title
NO941550L (fr)
US4377526A (en) Method of purifying eicosapentaenoic acid and its esters
CA2043615A1 (fr) Methode de preparation de l'acide icosapentenoique ou d'un ester de ce dernier
AU3388289A (en) Purification of fish oil
DK0697034T3 (da) Fremgangsmåder til kromatografisk fraktionering af fedtsyrer og deres derivater
ES2017268A6 (es) Procedimiento para preparar mezclas de alta concentracion de acidos grasos poliinsaturados y de sus esteres, a partir de aceites de origen animal yno vegetal, mezclas asi obtenidas y su uso para fines dietetico-alimentarios.
FR2710638B1 (fr) Procédé de préparation d'isomères d'acides benzènedicarboxyliques de haute pureté.
KR900002771A (ko) 지방산 조성물
PL312565A1 (en) Method of manufacturing alkyl esters of fatty acids
CA2273570A1 (fr) Concentration et purification d'ester d'acides gras polyinsatures par distillation-transesterification enzymatique
RO105609B1 (ro) Procedeu de transvinilare a derivatilor vinilici cu acizi bronsted
GB1500474A (en) Process for preparing purified methacrylates
DE59106041D1 (de) Polyglycerinfettsäureestergemisch.
MY109839A (en) Triglyceride fractionation
CA2220463A1 (fr) Procede d'amelioration de la couleur et de la stabilite de la couleur de l'acide oleique
JP3614177B2 (ja) 高純度ドコサヘキサエン酸またはそのエステルの 製造方法
ATE297371T1 (de) Verfahren zur herstellung von hochreinen fettsäure-niedrigalkylestern
GB2350610A (en) Preparation of pure unsaturated fatty acids
JPS6448898A (en) Production of eicosapentaenoic acid or ester thereof and docosahexaenoic acid or ester thereof
Painuly et al. Purification of erucic acid by preparative high-performance liquid chromatography and crystallization
FR2650274B1 (fr) Procede de fractionnement d'un melange d'esters d'acides gras
JPS51131506A (en) A method for the fractionation of solid fats
JPS5446710A (en) Separation of mixed solution of dicarbolylic acid and its ester

Legal Events

Date Code Title Description
MK1K Patent expired