NO944093L - Lineære adhesjonsinhibitorer - Google Patents

Lineære adhesjonsinhibitorer

Info

Publication number: NO944093L
Authority: NO; Norway
Prior art keywords: disorders; adhesion inhibitors; linear adhesion; linear; aiibss3
Prior art date: 1993-10-28

Application number

NO944093A

Other languages

English (en)

Norwegian (no)

Other versions

NO944093D0 (no

Inventor

Alfred Jonczyk

Brunhilde Felding-Habermann

Beate Diefenbach

Friedrich Rippmann

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-28

Filing date

1994-10-27

Publication date

1995-05-02

1994-10-27 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1994-10-27 Publication of NO944093D0 publication Critical patent/NO944093D0/no

1995-05-02 Publication of NO944093L publication Critical patent/NO944093L/no

Links

239000003112 inhibitor Substances 0.000 title abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
206010003210 Arteriosclerosis Diseases 0.000 abstract 1
201000001320 Atherosclerosis Diseases 0.000 abstract 1
206010061216 Infarction Diseases 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
208000007536 Thrombosis Diseases 0.000 abstract 1
208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
210000001772 blood platelet Anatomy 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
208000019622 heart disease Diseases 0.000 abstract 1
230000007574 infarction Effects 0.000 abstract 1
102000006495 integrins Human genes 0.000 abstract 1
108010044426 integrins Proteins 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000000010 osteolytic effect Effects 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
230000029663 wound healing Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Public Health (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Medicinal Preparation (AREA)

NO944093A 1993-10-28 1994-10-27 Lineære adhesjonsinhibitorer NO944093L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4336758A DE4336758A1 (de)	1993-10-28	1993-10-28	Lineare Adhäsionsinhibitoren

Publications (2)

Publication Number	Publication Date
NO944093D0 NO944093D0 (no)	1994-10-27
NO944093L true NO944093L (no)	1995-05-02

Family

ID=6501202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO944093A NO944093L (no)	1993-10-28	1994-10-27	Lineære adhesjonsinhibitorer

Country Status (16)

Country	Link
US (1)	US5747457A (ja)
EP (1)	EP0655462B1 (ja)
JP (1)	JPH07149794A (ja)
KR (1)	KR950011466A (ja)
CN (1)	CN1107159A (ja)
AT (1)	ATE165837T1 (ja)
AU (1)	AU690923B2 (ja)
CA (1)	CA2134418A1 (ja)
CZ (1)	CZ265594A3 (ja)
DE (2)	DE4336758A1 (ja)
HU (1)	HUT69179A (ja)
NO (1)	NO944093L (ja)
PL (1)	PL305632A1 (ja)
RU (1)	RU94039288A (ja)
SK (1)	SK130094A3 (ja)
ZA (1)	ZA948479B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6100423A (en) *	1995-08-30	2000-08-08	G. D. Searle & Co.	Amino benzenepropanoic acid compounds and derivatives thereof
IL123164A (en)	1995-08-30	2001-03-19	Searle & Co	Meta-guanidine urea thiourea or azacyclic amino benzoic acid derivatives and pharmaceutical compositions containing them
DE19534016A1 (de) *	1995-09-14	1997-03-20	Merck Patent Gmbh	Biotinderivate
AU2592600A (en)	1998-12-23	2000-07-31	G.D. Searle & Co.	Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
ES2436170T3 (es) *	2003-12-03	2013-12-27	The Scripps Research Institute	Anticuerpos y péptidos específicos de la integrina alfa II beta3
CN108203465B (zh) *	2016-12-20	2022-09-02	山西医科大学	一种双重靶向抑制肿瘤细胞和肿瘤血管且性质稳定的多肽

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2799670A (en) *	1954-04-13	1957-07-16	Laufer Louis	Method of preparing cysteinylglycine
US4177277A (en) *	1977-01-17	1979-12-04	E. R. Squibb & Sons, Inc.	Method for alleviating hypertension
JP2945680B2 (ja) *	1988-09-09	1999-09-06	旭硝子株式会社	ペプチド誘導体およびその用途
JPH02275899A (ja) *	1989-02-09	1990-11-09	Merck & Co Inc	ポリペプチド合成
AU5939890A (en) *	1989-06-07	1991-01-07	Genentech Inc.	Platelet aggregation inhibitors and related molecules

1993
- 1993-10-28 DE DE4336758A patent/DE4336758A1/de not_active Withdrawn
1994
- 1994-10-20 DE DE59405893T patent/DE59405893D1/de not_active Expired - Fee Related
- 1994-10-20 EP EP94116556A patent/EP0655462B1/de not_active Expired - Lifetime
- 1994-10-20 AT AT94116556T patent/ATE165837T1/de not_active IP Right Cessation
- 1994-10-24 JP JP6258198A patent/JPH07149794A/ja active Pending
- 1994-10-26 CN CN94117737A patent/CN1107159A/zh active Pending
- 1994-10-26 AU AU77501/94A patent/AU690923B2/en not_active Ceased
- 1994-10-26 SK SK1300-94A patent/SK130094A3/sk unknown
- 1994-10-26 CA CA002134418A patent/CA2134418A1/en not_active Abandoned
- 1994-10-27 KR KR1019940027613A patent/KR950011466A/ko not_active Withdrawn
- 1994-10-27 HU HU9403100A patent/HUT69179A/hu unknown
- 1994-10-27 ZA ZA948479A patent/ZA948479B/xx unknown
- 1994-10-27 RU RU94039288/04A patent/RU94039288A/ru unknown
- 1994-10-27 PL PL94305632A patent/PL305632A1/xx unknown
- 1994-10-27 US US08/329,820 patent/US5747457A/en not_active Expired - Fee Related
- 1994-10-27 NO NO944093A patent/NO944093L/no unknown
- 1994-10-27 CZ CZ942655A patent/CZ265594A3/cs unknown

Also Published As

Publication number	Publication date
CN1107159A (zh)	1995-08-23
SK130094A3 (en)	1995-05-10
PL305632A1 (en)	1995-05-02
EP0655462A1 (de)	1995-05-31
HU9403100D0 (en)	1994-12-28
JPH07149794A (ja)	1995-06-13
US5747457A (en)	1998-05-05
HUT69179A (en)	1995-08-28
AU7750194A (en)	1995-05-18
NO944093D0 (no)	1994-10-27
ATE165837T1 (de)	1998-05-15
AU690923B2 (en)	1998-05-07
DE59405893D1 (de)	1998-06-10
ZA948479B (en)	1995-06-20
DE4336758A1 (de)	1995-05-04
CZ265594A3 (en)	1995-07-12
CA2134418A1 (en)	1995-04-29
RU94039288A (ru)	1996-09-10
KR950011466A (ko)	1995-05-15
EP0655462B1 (de)	1998-05-06

Publication	Publication Date	Title
RU94031102A (ru)	1996-07-10	Сульфамиды в качестве антагонистов эндотелина и способ лечения соответствующих заболеваний
ATE207355T1 (de)	2001-11-15	Behandlung von hyperproliferativen gefässerkrankungen
FR2698780B1 (fr)	1995-06-23	Catheter pour le traitement d'un tissu pathologique.
DE68913667D1 (de)	1994-04-14	Imidazole für die Behandlung von Atherosclerose.
NO923130D0 (no)	1992-08-11	Behandling av kongestiv hjertesvikt
EP0458641A3 (en)	1992-10-28	Use of prostaglandin derivatives in the treatment of congestive heart failure
FI892065A7 (fi)	1989-04-28	Transformoidut maitohappobakteerit
TR199901962T2 (xx)	1999-12-21	Bisiklik amino asitler.
DE69429160D1 (de)	2002-01-03	Behandlung von textilprodukt
DK465488D0 (da)	1988-08-19	Farmaceutisk praeparat indeholdende en triazol-forbindelse
NO944093D0 (no)	1994-10-27	Lineære adhesjonsinhibitorer
DE69110937D1 (de)	1995-08-10	Herzschrittmacher zur Beendung von Herzarrhythmia.
EP0302595A3 (en)	1990-11-14	Pinacidil for treatment of pulmonary hypertension or right heart failure
RU96112829A (ru)	1998-09-27	Способ лечения ишемической болезни сердца
DE58906814D1 (de)	1994-03-10	Verwendung von ACE-Inhibitoren gegen Neointimabildung nach Gefässverletzung.
DE69121104D1 (de)	1996-08-29	Frequenzadaptierender herzschrittmacher
DE68911776D1 (de)	1994-02-10	Konjugierte Oxybutenolide zur Behandlung von Ulcera.
BR9810394A (pt)	2000-09-05	Azapeptìdeos cìclicos
SE8301004D0 (sv)	1983-02-23	Pyridinforeningar
ATE100826T1 (de)	1994-02-15	Behandlung von celluloseblaettern.
CA2185394A1 (en)	1997-03-15	Biotinderivate
GEP20012511B (en)	2001-08-27	Method for Lowering Level of Lipoproteins (a) in Serum or Plasma of Mammals, Method for Treatment of Peripheral Vascular Diseases or Restenosis
DE3888228D1 (de)	1994-04-14	Bakterienzellulose für die Oberflächenbehandlung von Faserbahnen.
DK455185A (da)	1986-04-06	Pyridinderivater
DE69522685D1 (de)	2001-10-18	Behandlung von blut-plasma