NO952198L - Triazolbenzazepinderivater med antiallergisk virkning - Google Patents

Triazolbenzazepinderivater med antiallergisk virkning

Info

Publication number: NO952198L
Authority: NO; Norway
Prior art keywords: 4alkyl; pct; substituted; hydroxycarbonyl; alk
Prior art date: 1992-12-04

Application number

NO952198A

Other languages

English (en)

Other versions

NO305250B1 (no

NO952198D0 (no

Inventor

Frans Eduard Janssens

Jean Fernand Armand Lacrampe

Isabelle Noelle Consta Pilatte

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-04

Filing date

1995-06-02

Publication date

1995-08-03

1995-06-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1995-06-02 Publication of NO952198D0 publication Critical patent/NO952198D0/no

1995-08-03 Publication of NO952198L publication Critical patent/NO952198L/no

1999-04-26 Publication of NO305250B1 publication Critical patent/NO305250B1/no

Links

-1 Triazole benzazepine derivatives Chemical class 0.000 title 1
230000003266 anti-allergic effect Effects 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
150000002431 hydrogen Chemical group 0.000 abstract 4
125000001475 halogen functional group Chemical group 0.000 abstract 3
ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 3
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pulmonology (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

NO952198A 1992-12-04 1995-06-02 Triazolbenzazepinderivater med antiallergisk virkning NO305250B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP92203776		1992-12-04
PCT/EP1993/003320 WO1994013671A1 (en)	1992-12-04	1993-11-25	Antiallergic triazolobenzazepine derivatives

Publications (3)

Publication Number	Publication Date
NO952198D0 NO952198D0 (no)	1995-06-02
NO952198L true NO952198L (no)	1995-08-03
NO305250B1 NO305250B1 (no)	1999-04-26

Family

ID=8211104

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO952198A NO305250B1 (no)	1992-12-04	1995-06-02	Triazolbenzazepinderivater med antiallergisk virkning

Country Status (16)

Country	Link
US (1)	US5932569A (no)
EP (1)	EP0675887B1 (no)
JP (1)	JP3572074B2 (no)
KR (1)	KR100251893B1 (no)
AT (1)	ATE236164T1 (no)
AU (1)	AU676701B2 (no)
CA (1)	CA2150806C (no)
DE (1)	DE69332830T2 (no)
ES (1)	ES2196020T3 (no)
FI (1)	FI952722A0 (no)
HU (1)	HU223464B1 (no)
NO (1)	NO305250B1 (no)
NZ (1)	NZ258551A (no)
PL (1)	PL176593B1 (no)
RU (1)	RU2126802C1 (no)
WO (1)	WO1994013671A1 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU223465B1 (hu) *	1992-12-04	2004-07-28	Janssen Pharmaceutica N.V.	Allergia elleni triazolo(pirrolo, tieno vagy furán)-azepin-származékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
US7476662B2 (en)	2001-06-12	2009-01-13	Janssen Pharmaceutica N.V.	Substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine
EP1785424A3 (en) *	2003-04-11	2009-12-23	High Point Pharmaceuticals, LLC	Fused 1,2,4-triazoles and pharmaceutical uses thereof
EP1615647B1 (en) *	2003-04-11	2010-01-20	High Point Pharmaceuticals, LLC	Pharmaceutical use of fused 1,2,4-triazoles
RU2239637C1 (ru) *	2003-07-17	2004-11-10	Дж.Б.Кемикалс Энд Фармасьютикалс Лтд.	Улучшенный способ получения 5-[2-этокси-5-(4-метилпиперазин-1-илсульфонил)фенил]-1 метил-3-н-пропил-1,6-дигидро-7h-пиразол [4,3-d] пиримидин-7-она
EP1802623A1 (en) *	2004-10-12	2007-07-04	Novo Nordisk A/S	11beta-hydroxysteroid dehydrogenase type 1 active spiro compounds
EA200801243A1 (ru) *	2005-11-01	2008-10-30	Транстек Фарма	Фармацевтическое применение замещенных амидов
KR20080069189A (ko) *	2005-11-01	2008-07-25	트랜스테크 파르마, 인크.	치환된 아미드의 약학적 사용
JP2009530346A (ja) *	2006-03-21	2009-08-27	ハイポイントファーマシューティカルズ，リミティドライアビリティカンパニー	メタボリックシンドロームの治療用のアダマンタン誘導体
KR20090014347A (ko)	2006-04-07	2009-02-10	하이 포인트 파마슈티칼스, 엘엘씨	11β-히드록시스테로이드 탈수소효소 타입 1 활성 화합물
EP1878721A1 (en) *	2006-07-13	2008-01-16	Novo Nordisk A/S	4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
WO2008006702A1 (en) *	2006-07-13	2008-01-17	High Point Pharmaceuticals, Llc.	11beta-hydroxysteroid dehydrogenase type 1 active compounds
WO2008101885A1 (en) *	2007-02-23	2008-08-28	High Point Pharmaceuticals, Llc	N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
EP2150526B1 (en)	2007-02-23	2017-09-20	vTv Therapeutics LLC	N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
EP2125704A1 (en) *	2007-02-23	2009-12-02	High Point Pharmaceuticals, LLC	N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
EP2129652A2 (en) *	2007-02-23	2009-12-09	High Point Pharmaceuticals, LLC	N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
WO2008110196A1 (en) *	2007-03-09	2008-09-18	High Point Pharmaceuticals, Llc	Indole- and benzimidazole amides as hydroxysteroid dehydrogenase inhibitors
US20100056600A1 (en) *	2007-03-28	2010-03-04	Soren Ebdrup	11beta-hsd1 active compounds
CN101677562A (zh) *	2007-04-11	2010-03-24	高点制药有限责任公司	新化合物
ES2393230T3 (es) *	2007-04-24	2012-12-19	High Point Pharmaceuticals, Llc	Uso farmacéutico de amidas sustituidas
KR102431436B1 (ko)	2014-08-29	2022-08-10	테스 파마 에스.알.엘.	α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1211437A (en) *	1981-08-12	1986-09-16	Rene Borer	Benzazepines
US4894372A (en) *	1982-03-17	1990-01-16	Smith Kline & French Laboratories Limited	Pyridine compounds which have useful histamine-H2 antagonist activity
DE69110685T2 (de) *	1990-10-10	1995-11-09	Schering Corp	Substituierte imidazobenzazepine und imidazopyridoazepine.
IL101850A (en) *	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
HU223465B1 (hu) *	1992-12-04	2004-07-28	Janssen Pharmaceutica N.V.	Allergia elleni triazolo(pirrolo, tieno vagy furán)-azepin-származékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények
ES2199224T3 (es) *	1992-12-04	2004-02-16	Janssen Pharmaceutica N.V.	Derivados de imidazo(1,2-a)tieno(2,3-d)azepina antialergicos.

1993
- 1993-11-25 CA CA002150806A patent/CA2150806C/en not_active Expired - Fee Related
- 1993-11-25 ES ES94901886T patent/ES2196020T3/es not_active Expired - Lifetime
- 1993-11-25 US US08/433,388 patent/US5932569A/en not_active Expired - Fee Related
- 1993-11-25 DE DE69332830T patent/DE69332830T2/de not_active Expired - Fee Related
- 1993-11-25 JP JP51372094A patent/JP3572074B2/ja not_active Expired - Fee Related
- 1993-11-25 AT AT94901886T patent/ATE236164T1/de not_active IP Right Cessation
- 1993-11-25 NZ NZ258551A patent/NZ258551A/en unknown
- 1993-11-25 WO PCT/EP1993/003320 patent/WO1994013671A1/en not_active Ceased
- 1993-11-25 PL PL93309253A patent/PL176593B1/pl not_active IP Right Cessation
- 1993-11-25 AU AU56278/94A patent/AU676701B2/en not_active Ceased
- 1993-11-25 HU HU9501621A patent/HU223464B1/hu not_active IP Right Cessation
- 1993-11-25 EP EP94901886A patent/EP0675887B1/en not_active Expired - Lifetime
- 1993-11-25 RU RU95114439A patent/RU2126802C1/ru not_active IP Right Cessation
- 1993-11-25 KR KR1019950702169A patent/KR100251893B1/ko not_active Expired - Fee Related
1995
- 1995-06-02 FI FI952722A patent/FI952722A0/fi unknown
- 1995-06-02 NO NO952198A patent/NO305250B1/no unknown

Also Published As

Publication number	Publication date
NO305250B1 (no)	1999-04-26
KR100251893B1 (ko)	2000-04-15
JP3572074B2 (ja)	2004-09-29
HU9501621D0 (en)	1995-08-28
HUT71811A (en)	1996-02-28
AU676701B2 (en)	1997-03-20
CA2150806C (en)	2006-01-31
EP0675887A1 (en)	1995-10-11
ES2196020T3 (es)	2003-12-16
DE69332830D1 (de)	2003-05-08
FI952722A7 (fi)	1995-06-02
US5932569A (en)	1999-08-03
AU5627894A (en)	1994-07-04
PL176593B1 (pl)	1999-06-30
HU223464B1 (hu)	2004-07-28
RU95114439A (ru)	1997-06-10
NZ258551A (en)	1996-06-25
FI952722A0 (fi)	1995-06-02
WO1994013671A1 (en)	1994-06-23
DE69332830T2 (de)	2004-01-29
PL309253A1 (en)	1995-10-02
RU2126802C1 (ru)	1999-02-27
JPH08503952A (ja)	1996-04-30
EP0675887B1 (en)	2003-04-02
NO952198D0 (no)	1995-06-02
ATE236164T1 (de)	2003-04-15
CA2150806A1 (en)	1994-06-23

Publication	Publication Date	Title
NO305250B1 (no)	1999-04-26	Triazolbenzazepinderivater med antiallergisk virkning
MY117557A (en)	2004-07-31	1-(1,2-disubstituted piperidinyl)-4- substituted piperidine derivatives
CA2234096A1 (en)	1997-05-09	1-(1,2-disubstituted piperidinyl)-4-substituted piperazine derivatives
NL350075I2 (no)	2017-02-07
GR3034991T3 (en)	2001-03-30	Dihydrobenzofuranes
EE200100350A (et)	2002-10-15	Fenüülfenantridiinid, nende kasutamine ravimite valmistamiseks ning neid sisaldav ravim
AU2291097A (en)	1997-10-17	Novel phenanthridines substituted in the 6 position
NO924929L (no)	1992-12-18	Farmasoeytisk aktive benzoquinazolinforbindelser
TW429256B (en)	2001-04-11	1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives
IT1243801B (it)	1994-06-28	Intermedi per agenti chelanti con simmetria prefissata, e procedimentoper la loro preparazione
WO2003022797A1 (en)	2003-03-20	Carba-sugar amine derivatives and treatments for disorder of glycolipid metabolism containing the same as the active ingredient
SE9603285D0 (sv)	1996-09-10	New compounds
DE59604901D1 (de)	2000-05-11	Carbamoylcarbonsäureamide
NO952200D0 (no)	1995-06-02	Triazol (pyrrol, Tien eller furan)-azepinderivater med antiallergisk virkning
NZ501982A (en)	2000-10-27	N-oxide forms of 2,4,4-trisubstituted-1,3-dioxolane as anti-fungal agents
DK1104419T3 (da)	2002-09-23	N-substituerede azabicyloheptan-derivater, deres fremstilling og anvendelse
ATE227989T1 (de)	2002-12-15	Zubereitung enthaltend derivate von phenylaminothiophenessigsäure zur behandlung der akuten respiratorischen insuffizienz (ards) und der akuten respiratorischen insuffizienz bei kindern (irds)
NO932002L (no)	1993-12-06	Nye tiosemikarbazonsyreestere
NO952292D0 (no)	1995-06-09	Nye triazolokinazoliner, deres fremstilling og anvendelse
DK0662081T3 (da)	1997-05-05	Ureidoacetamidderivater, deres fremstilling og lægemidler indeholdende disse derivater