NO960029L - Nye (1-fenyl-1-heterocyklyl)alkanderivater og deres anvendelse som neurobeskyttelsesmidler - Google Patents

Nye (1-fenyl-1-heterocyklyl)alkanderivater og deres anvendelse som neurobeskyttelsesmidler

Info

Publication number
NO960029L
NO960029L NO960029A NO960029A NO960029L NO 960029 L NO960029 L NO 960029L NO 960029 A NO960029 A NO 960029A NO 960029 A NO960029 A NO 960029A NO 960029 L NO960029 L NO 960029L
Authority
NO
Norway
Prior art keywords
heterocyclyl
phenyl
new
neuroprotective agents
alkane derivatives
Prior art date
Application number
NO960029A
Other languages
English (en)
Other versions
NO305862B1 (no
NO960029D0 (no
Inventor
Bernard Robin Boar
Alan John Cross
Duncan Alastair Gray
Alfred Richard Green
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO960029L publication Critical patent/NO960029L/no
Publication of NO960029D0 publication Critical patent/NO960029D0/no
Publication of NO305862B1 publication Critical patent/NO305862B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO960029A 1993-07-06 1996-01-04 Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler NO305862B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939302333A SE9302333D0 (sv) 1993-07-06 1993-07-06 New compounds
PCT/SE1994/000664 WO1995001967A1 (en) 1993-07-06 1994-07-05 Novel (1-phenyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents

Publications (3)

Publication Number Publication Date
NO960029L true NO960029L (no) 1996-01-04
NO960029D0 NO960029D0 (no) 1996-01-04
NO305862B1 NO305862B1 (no) 1999-08-09

Family

ID=20390540

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960029A NO305862B1 (no) 1993-07-06 1996-01-04 Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler

Country Status (18)

Country Link
US (1) US5747515A (no)
EP (1) EP0707573A1 (no)
JP (1) JPH08512313A (no)
CN (1) CN1044705C (no)
AU (1) AU691191B2 (no)
BR (1) BR9406924A (no)
CA (1) CA2164876A1 (no)
CZ (1) CZ4196A3 (no)
FI (1) FI960077A7 (no)
HU (1) HUT74673A (no)
IS (1) IS1742B (no)
NO (1) NO305862B1 (no)
NZ (1) NZ268690A (no)
PL (1) PL179021B1 (no)
RU (1) RU2137763C1 (no)
SE (1) SE9302333D0 (no)
SK (1) SK281025B6 (no)
WO (1) WO1995001967A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726569D0 (en) * 1997-12-16 1998-02-11 Univ Southampton Neuroprotective agents
FR2774596B1 (fr) * 1998-02-11 2000-03-17 Rhone Poulenc Rorer Sa Utilisation de composes selenies dans la prevention et le traitement de la maladie d'alzheimer
WO1999054309A1 (en) * 1998-04-23 1999-10-28 Takeda Chemical Industries, Ltd. Naphthalene derivatives, their production and use
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
US6156775A (en) * 1999-03-01 2000-12-05 Novartis Ag Use of fluorinated triazoles in treating affective and attention disorders
AU5566400A (en) * 1999-06-22 2001-01-09 Takeda Chemical Industries Ltd. Process for the preparation of imidazole derivatives
SE9904177D0 (sv) * 1999-11-18 1999-11-18 Astra Ab Novel compounds
RU2275195C2 (ru) * 2003-06-19 2006-04-27 Наталья Борисовна Кармен Средство для защиты головного мозга от гипоксически-ишемического повреждения
EP1735287A1 (en) * 2004-04-03 2006-12-27 Astrazeneca AB Therapeutic agents
WO2008064317A1 (en) * 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Lipophilic opioid receptor active compounds
JP2014525442A (ja) * 2011-08-30 2014-09-29 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
CN104932538B (zh) * 2015-07-03 2018-02-23 中国计量科学研究院 光机旋转装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE121520C (no) *
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
FR2625199B1 (fr) * 1987-12-23 1991-03-22 Irceba Derives oxyimino du thiazole, procede de preparation et utilisation en therapeutique
DE3884966T2 (de) * 1987-12-29 1994-02-03 Dainippon Pharmaceutical Co Mittel zur behandlung der ischämischen gehirnkrankheit.
JPH01249760A (ja) * 1988-03-29 1989-10-05 Yamaha Corp ホトクロミック化合物
JPH0291076A (ja) * 1988-09-28 1990-03-30 Tokuyama Soda Co Ltd フォトクロミック性化合物及びその製造方法
GB8909737D0 (en) * 1989-04-27 1989-06-14 Shell Int Research Thiazole derivatives
TW224461B (no) * 1990-09-18 1994-06-01 Ciba Geigy Ag
US5177079A (en) * 1991-01-31 1993-01-05 Warner-Lambert Company 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
CA2099868C (en) * 1991-01-31 2002-04-02 Thomas Richard Belliotti Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines
GB9125924D0 (en) * 1991-06-18 1992-02-05 Orion Yhtymae Oy Stereoisomers of an imidazole derivative

Also Published As

Publication number Publication date
SE9302333D0 (sv) 1993-07-06
PL179021B1 (pl) 2000-07-31
RU2137763C1 (ru) 1999-09-20
FI960077A0 (fi) 1996-01-08
FI960077A7 (fi) 1996-01-08
BR9406924A (pt) 1996-07-30
CA2164876A1 (en) 1995-01-19
CN1044705C (zh) 1999-08-18
NZ268690A (en) 1997-11-24
NO305862B1 (no) 1999-08-09
SK159995A3 (en) 1996-06-05
IS4183A (is) 1995-01-07
PL312427A1 (en) 1996-04-29
HU9503742D0 (en) 1996-02-28
HUT74673A (en) 1997-01-28
WO1995001967A1 (en) 1995-01-19
NO960029D0 (no) 1996-01-04
IS1742B (is) 2000-02-21
JPH08512313A (ja) 1996-12-24
AU691191B2 (en) 1998-05-14
CZ4196A3 (en) 1996-06-12
CN1126990A (zh) 1996-07-17
US5747515A (en) 1998-05-05
SK281025B6 (sk) 2000-11-07
EP0707573A1 (en) 1996-04-24
AU7197894A (en) 1995-02-06

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Free format text: LAPSED IN JANUARY 2002