NO963805L - Cefalosporinderivater - Google Patents

Cefalosporinderivater

Info

Publication number: NO963805L
Authority: NO; Norway
Prior art keywords: fluoro; lower alkyl; hydroxyphenyl; carboxy; substituted
Prior art date: 1995-09-12

Application number

NO963805A

Other languages

English (en)

Norwegian (no)

Other versions

NO963805D0 (no

Inventor

Paul Hebeisen

Ingrid Heinze-Krauss

Hans Richter

Valeri Runtz

Henri Stalder

Urs Weiss

George Petros Yiannikouros

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-12

Filing date

1996-09-11

Publication date

1997-03-13

1996-09-11 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1996-09-11 Publication of NO963805D0 publication Critical patent/NO963805D0/no

1997-03-13 Publication of NO963805L publication Critical patent/NO963805L/no

Links

229930186147 Cephalosporin Natural products 0.000 title abstract 2
229940124587 cephalosporin Drugs 0.000 title abstract 2
150000001780 cephalosporins Chemical class 0.000 title abstract 2
-1 4-carboxyphenyl Chemical group 0.000 abstract 12
125000000217 alkyl group Chemical group 0.000 abstract 5
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
125000005843 halogen group Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
YCWRFIYBUQBHJI-UHFFFAOYSA-N 2-(4-aminophenyl)acetonitrile Chemical group NC1=CC=C(CC#N)C=C1 YCWRFIYBUQBHJI-UHFFFAOYSA-N 0.000 abstract 1
125000004847 2-fluorobenzyl group Chemical group [H]C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000004198 2-fluorophenyl group Chemical group [H]C1=C([H])C(F)=C(*)C([H])=C1[H] 0.000 abstract 1
125000002927 2-methoxybenzyl group Chemical group [H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])* 0.000 abstract 1
125000004204 2-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C(OC([H])([H])[H])C([H])=C1[H] 0.000 abstract 1
125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
125000006284 3-fluorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C(F)=C1[H])C([H])([H])* 0.000 abstract 1
125000004180 3-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(F)=C1[H] 0.000 abstract 1
125000006291 3-hydroxybenzyl group Chemical group [H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])* 0.000 abstract 1
125000004208 3-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C([H])C(*)=C1[H] 0.000 abstract 1
125000006497 3-methoxybenzyl group Chemical group [H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])* 0.000 abstract 1
125000004207 3-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(OC([H])([H])[H])=C1[H] 0.000 abstract 1
125000004176 4-fluorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])* 0.000 abstract 1
125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004217 4-methoxybenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])* 0.000 abstract 1
125000001318 4-trifluoromethylbenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])*)C(F)(F)F 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 abstract 1
125000003386 piperidinyl group Chemical group 0.000 abstract 1
125000003373 pyrazinyl group Chemical class 0.000 abstract 1
125000002098 pyridazinyl group Chemical group 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000714 pyrimidinyl group Chemical class 0.000 abstract 1
125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1
125000003831 tetrazolyl group Chemical group 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO963805A 1995-09-12 1996-09-11 Cefalosporinderivater NO963805L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95114304		1995-09-12
EP95114303		1995-09-12

Publications (2)

Publication Number	Publication Date
NO963805D0 NO963805D0 (no)	1996-09-11
NO963805L true NO963805L (no)	1997-03-13

Family

ID=26138799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO963805A NO963805L (no)	1995-09-12	1996-09-11	Cefalosporinderivater

Country Status (15)

Country	Link
US (1)	US5804577A (fr)
JP (1)	JPH09132578A (fr)
KR (1)	KR100209839B1 (fr)
CN (1)	CN1060778C (fr)
AU (1)	AU709077B2 (fr)
CA (1)	CA2184971A1 (fr)
CO (1)	CO4750667A1 (fr)
CZ (1)	CZ251896A3 (fr)
HU (1)	HUP9602433A3 (fr)
IL (1)	IL119215A0 (fr)
MA (1)	MA23970A1 (fr)
NO (1)	NO963805L (fr)
PL (1)	PL316032A1 (fr)
SG (1)	SG52841A1 (fr)
TR (1)	TR199600715A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4033630B2 (ja) *	1998-06-22	2008-01-16	バジリアファルマスーチカアーゲー	プロペニルセファロスポリン誘導体
EP1006689B1 (fr) *	1998-11-30	2008-02-06	Matsushita Electric Industries Co., Ltd.	Commande de retransmission de paquets utilisant des informations prioritaires
ES2251508T3 (es) *	2000-08-14	2006-05-01	Basilea Pharmaceutica Ag	Preparacion de sales de fosfonio sustituidas por 3-pirrolidina lactama n-protegida.
RU2361872C2 (ru) *	2004-05-26	2009-07-20	Эйсай Ар Энд Ди Менеджмент Ко., Лтд.	Циннамидное соединение
DE602005019602D1 (de)	2004-10-26	2010-04-08	Eisai R&D Man Co Ltd	Amorphe form einer zimtsäureamidverbindung
US20090048448A1 (en) *	2005-11-18	2009-02-19	Ikuo Kushida	Salts of cynnamide compound or solvates thereof
CN101309916A (zh) *	2005-11-18	2008-11-19	卫材R&D管理有限公司	制备肉桂酰胺衍生物的方法
TWI378091B (en)	2006-03-09	2012-12-01	Eisai R&D Man Co Ltd	Multi-cyclic cinnamide derivatives
KR20090016591A (ko) *	2006-05-19	2009-02-16	에자이 알앤드디 매니지먼트 가부시키가이샤	헤테로사이클 타입의 신나미드 유도체
JPWO2007135969A1 (ja) *	2006-05-19	2009-10-01	エーザイ・アール・アンド・ディー・マネジメント株式会社	ウレア系−シンナミド誘導体
CL2008000582A1 (es) *	2007-02-28	2008-06-27	Eisai R&D Man Co Ltd	Compuestos ciclicos derivados de oximorfolina condensados; farmacos que comprenden a dichos compuestos; y su uso para tratar enfermedad de alzheimer, demencia senil, sindrome de down o amiloidosis.
US20080306272A1 (en) *	2007-05-16	2008-12-11	Eisai R&D Management Co., Ltd.	One-pot methods for preparing cinnamide derivatives
US7935815B2 (en)	2007-08-31	2011-05-03	Eisai R&D Management Co., Ltd.	Imidazoyl pyridine compounds and salts thereof
BRPI0815773A2 (pt) *	2007-08-31	2019-09-24	Eisai R&D Man Co Ltd	composto, e, medicamento.
WO2009096349A1 (fr) *	2008-01-28	2009-08-06	Eisai R & D Management Co., Ltd.	Composés cristallins de cinnamide ou sels de ceux-ci

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4255423A (en) *	1977-07-27	1981-03-10	Merck & Co., Inc.	Cephalosporin compounds
GB8821797D0 (en) *	1988-09-16	1988-10-19	Beecham Group Plc	Novel compounds
PT620225E (pt) *	1993-04-16	2003-03-31	Basilea Pharmaceutica Ag	Derivados de cefalosporina
US5523400A (en) *	1993-04-16	1996-06-04	Hoffmann-La Roche Inc.	Cephalosporin antibiotics

1996
- 1996-08-27 CZ CZ962518A patent/CZ251896A3/cs unknown
- 1996-08-27 US US08/708,161 patent/US5804577A/en not_active Expired - Fee Related
- 1996-09-05 HU HU9602433A patent/HUP9602433A3/hu unknown
- 1996-09-06 AU AU65506/96A patent/AU709077B2/en not_active Ceased
- 1996-09-06 IL IL11921596A patent/IL119215A0/xx unknown
- 1996-09-06 CA CA002184971A patent/CA2184971A1/fr not_active Abandoned
- 1996-09-11 CN CN96112538A patent/CN1060778C/zh not_active Expired - Fee Related
- 1996-09-11 NO NO963805A patent/NO963805L/no not_active Application Discontinuation
- 1996-09-11 CO CO96048398A patent/CO4750667A1/es unknown
- 1996-09-11 PL PL96316032A patent/PL316032A1/xx unknown
- 1996-09-11 SG SG1996010602A patent/SG52841A1/en unknown
- 1996-09-12 KR KR1019960039493A patent/KR100209839B1/ko not_active Expired - Fee Related
- 1996-09-12 TR TR96/00715A patent/TR199600715A2/xx unknown
- 1996-09-12 JP JP8242253A patent/JPH09132578A/ja active Pending
- 1996-09-12 MA MA24350A patent/MA23970A1/fr unknown

Also Published As

Publication number	Publication date
JPH09132578A (ja)	1997-05-20
KR100209839B1 (ko)	1999-07-15
SG52841A1 (en)	1998-09-28
HUP9602433A2 (en)	1997-05-28
MA23970A1 (fr)	1997-04-01
IL119215A0 (en)	1996-12-05
PL316032A1 (en)	1997-03-17
US5804577A (en)	1998-09-08
CZ251896A3 (en)	1997-04-16
MX9604017A (es)	1997-07-31
AU6550696A (en)	1997-03-20
KR970015593A (ko)	1997-04-28
HU9602433D0 (en)	1996-10-28
CN1060778C (zh)	2001-01-17
HUP9602433A3 (en)	2001-04-28
CO4750667A1 (es)	1999-03-31
CN1150950A (zh)	1997-06-04
NO963805D0 (no)	1996-09-11
AU709077B2 (en)	1999-08-19
CA2184971A1 (fr)	1997-03-13
TR199600715A2 (tr)	1997-03-21

Legal Events

Date	Code	Title	Description
2002-06-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO963805L (no)	1997-03-13	Cefalosporinderivater
HU9301155D0 (en)	1993-07-28	Methods for producing steroide derivatives and for their application in medical treatment
NO20013369L (no)	2001-09-03	Arylpiperazinyl-cykloheksyl-indol-derivater for behandling av depresjon
IN2015DN01133A (fr)	2015-06-26
CA2296031A1 (fr)	1999-01-28	Nouveaux composes spiroazabicycliques heterocycliques
WO2004087056A3 (fr)	2005-02-24	Inhibiteurs bi-cycliques a base de pyrimidine de tgf$g(b)
NO991048L (no)	1999-05-03	Indazolderivater og deres anvendelse som inhibitorer av fosfodiesterase (PDE) type IV og fremstillingen av tumornekrosefaktor (TNF)
CA2066640A1 (fr)	1991-04-15	Composes heterocycliques
AU3821889A (en)	1990-01-25	4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use
WO2003051275A3 (fr)	2003-10-30	Derives de benzodiazepine, preparation et utilisation de ceux-ci
NO994900L (no)	1999-11-19	Forbindelser
HU9401298D0 (en)	1994-08-29	Substituted pyrrol derivatives
CA2073633A1 (fr)	1993-01-12	Utilisation des derives de la xanthine pour le traitement des lesions des cellules nerveuses secondaires et des troubles fonctionnels a la suite de traumatismes cranio-cerebraux
NO20022123L (no)	2002-05-03	Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
AU7624394A (en)	1995-04-03	Optically active imidazolidinone derivative and process for producing the same
NO20065873L (no)	2007-02-20	3-(4-(2-dihydroisoksazol-3-ylpyridin-5-yl)fenyl)-5-triazol-1-ylmetyloksoazolidin-2-on derivater som MAO inhibitorer i behandlingen av bakterielle infeksjoner
WO2004000214A3 (fr)	2004-03-25	Utilisation de composes presentant un noyau amine pour produire un medicament servant a traiter des pathologies associees au facteur viia
CA2048959A1 (fr)	1992-02-14	Les 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines et leurs derives
NO950974L (no)	1995-03-14	Nye N,N,N',N'-tetrasubstituert-1,2-etandiaminderivatforbindelser
PT90261A (pt)	1989-11-10	Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno
NO993372L (no)	1999-07-08	Substituerte 4-(6-fluor-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridin for behandling av CNS-forstyrrelser
AU538882B2 (en)	1984-08-30	2,3-dihydro-imidazo(1,2-g)pyridazine derivatives
NO911081L (no)	1991-09-23	Fremgangsmaate for fremstilling av substituerte puriner, og deres anvendelse som antivirale midler.
AU2287499A (en)	1999-08-09	Azetidinecarboxamide derivatives for treating cns disorders
AU570541B2 (en)	1988-03-17	Pharmaceutically active piperidine derivatives