NO965097L - Nye elastaseinhibitorer - Google Patents

Nye elastaseinhibitorer

Info

Publication number
NO965097L
NO965097L NO965097A NO965097A NO965097L NO 965097 L NO965097 L NO 965097L NO 965097 A NO965097 A NO 965097A NO 965097 A NO965097 A NO 965097A NO 965097 L NO965097 L NO 965097L
Authority
NO
Norway
Prior art keywords
inhibitors
elastase inhibitors
elastase
compounds
new
Prior art date
Application number
NO965097A
Other languages
English (en)
Norwegian (no)
Other versions
NO965097D0 (no
Inventor
Jr William Arthur Metz
Steven Lee Gallion
Joseph Paul Burkhart
Michael Richard Angelastro
Norton Paul Peet
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO965097D0 publication Critical patent/NO965097D0/no
Publication of NO965097L publication Critical patent/NO965097L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO965097A 1994-06-02 1996-11-29 Nye elastaseinhibitorer NO965097L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25279994A 1994-06-02 1994-06-02
PCT/US1995/005618 WO1995033763A1 (en) 1994-06-02 1995-05-05 Novel elastase inhibitors

Publications (2)

Publication Number Publication Date
NO965097D0 NO965097D0 (no) 1996-11-29
NO965097L true NO965097L (no) 1997-01-31

Family

ID=22957608

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965097A NO965097L (no) 1994-06-02 1996-11-29 Nye elastaseinhibitorer

Country Status (20)

Country Link
EP (1) EP0804465B1 (de)
JP (1) JP3623799B2 (de)
KR (1) KR100347285B1 (de)
CN (1) CN1149877A (de)
AT (1) ATE246708T1 (de)
AU (1) AU689589B2 (de)
CA (1) CA2189527C (de)
DE (1) DE69531459T2 (de)
DK (1) DK0804465T3 (de)
ES (1) ES2199992T3 (de)
FI (1) FI964781A7 (de)
HU (1) HU221197B1 (de)
IL (1) IL113940A (de)
NO (1) NO965097L (de)
NZ (1) NZ285565A (de)
PT (1) PT804465E (de)
SI (1) SI0804465T1 (de)
TW (1) TW403762B (de)
WO (1) WO1995033763A1 (de)
ZA (1) ZA954430B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221311B1 (en) * 1994-06-02 2002-09-28 Merrell Pharma Inc Perfluoroalkyl tripeptides inhibitors of elastase, pharmaceutical compositions comprising thereof and their use
AU696292B2 (en) * 1994-06-02 1998-09-03 Merrell Pharmaceuticals Inc. Acylated enol derivatives as prodrugs of elastase inhibitors
US6172044B1 (en) 1995-12-01 2001-01-09 Aventis Pharmaceuticals Inc. Acylated enol derivative of α-ketoesters and α-ketoamides
US5948886A (en) * 1996-11-20 1999-09-07 Hoechst Marion Roussel, Inc. Acylated enol derivatives of α-ketoesters and α-ketoamides
US6767991B1 (en) 1997-08-11 2004-07-27 Boehringer Ingelheim (Canada) Ltd. Hepatitis C inhibitor peptides
CA2522577C (en) 2003-05-21 2011-04-26 Boehringer Ingelheim International Gmbh Hepatitis c inhibitor compounds
UY29016A1 (es) 2004-07-20 2006-02-24 Boehringer Ingelheim Int Analogos de dipeptidos inhibidores de la hepatitis c
ES2366478T3 (es) 2004-07-20 2011-10-20 Boehringer Ingelheim International Gmbh Análogos peptídicos inhibidores de la hepatitis c.
JP2009538327A (ja) 2006-05-23 2009-11-05 アイアールエム・リミテッド・ライアビリティ・カンパニー チャネル活性化プロテアーゼ阻害剤である化合物および組成物
BRPI0807483A2 (pt) 2007-02-09 2014-05-13 Irm Llc Compostos e composições como inibidores de protease de ativação de canal
BR112022004861A2 (pt) 2019-09-17 2022-06-07 Univ Duke Alvelestat para uso no tratamento de rejeição de transplante, síndrome de bronquiolite obliterante e doença de transplante versus hospedeiro
SI4106757T1 (sl) 2020-04-16 2023-11-30 Mereo Biopharma 4 Limited Postopki, ki vključujejo zaviralec nevtrofilne elastaze alvelestat, za zdravljenje bolezni dihal, ki jo sproži pomanjkanje antitripsina alfa-1
IL312002A (en) 2021-10-20 2024-06-01 Mereo Biopharma 4 Ltd Neutrophil elastase inhibitors for use in the treatment of fibrosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8600263D0 (en) * 1985-01-22 1986-02-12 Ici America Inc Peptide derivatives
EP0204571B1 (de) * 1985-06-07 1992-01-22 Ici Americas Inc. Selektionierte Difluorverbindungen
CA2021660A1 (en) * 1989-07-26 1991-01-27 Philippe Bey Peptidase inhibitors
WO1992012140A1 (en) * 1990-12-28 1992-07-23 Georgia Tech Research Corporation Peptides ketoamides, ketoacids, and ketoesters
ZA926185B (en) * 1991-08-22 1993-03-01 Merrell Dow Pharma Novel orally-active elastase inhibitors.

Also Published As

Publication number Publication date
FI964781L (fi) 1997-01-29
ES2199992T3 (es) 2004-03-01
CA2189527C (en) 2000-12-19
ATE246708T1 (de) 2003-08-15
MX9606030A (es) 1998-05-31
JP3623799B2 (ja) 2005-02-23
FI964781A0 (fi) 1996-11-29
EP0804465A1 (de) 1997-11-05
AU2470995A (en) 1996-01-04
FI964781A7 (fi) 1997-01-29
DE69531459D1 (de) 2003-09-11
NZ285565A (en) 1998-08-26
PT804465E (pt) 2003-12-31
KR100347285B1 (ko) 2003-01-15
CA2189527A1 (en) 1995-12-14
JPH10500992A (ja) 1998-01-27
HU221197B1 (en) 2002-08-28
AU689589B2 (en) 1998-04-02
SI0804465T1 (en) 2003-12-31
IL113940A0 (en) 1995-08-31
HU9603312D0 (en) 1997-01-28
IL113940A (en) 1999-12-31
DK0804465T3 (da) 2003-11-24
DE69531459T2 (de) 2004-06-24
ZA954430B (en) 1996-02-13
NO965097D0 (no) 1996-11-29
CN1149877A (zh) 1997-05-14
EP0804465B1 (de) 2003-08-06
WO1995033763A1 (en) 1995-12-14
HUT76926A (hu) 1998-01-28
TW403762B (en) 2000-09-01

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