NO971934L - Flourinerte vitamin D3 -analoger - Google Patents

Flourinerte vitamin D3 -analoger

Info

Publication number: NO971934L
Authority: NO; Norway
Prior art keywords: analogues; fluorinated vitamin; disorders; hydroxyl; hydrogen
Prior art date: 1996-05-23

Application number

NO971934A

Other languages

English (en)

Norwegian (no)

Other versions

NO971934D0 (no

Inventor

Bernard Michael Hennessy

Milan Radoje Uskokovic

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-23

Filing date

1997-04-25

Publication date

1997-11-24

1997-04-25 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-04-25 Publication of NO971934D0 publication Critical patent/NO971934D0/no

1997-11-24 Publication of NO971934L publication Critical patent/NO971934L/no

Links

QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
208000015390 Sebaceous gland disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
230000003463 hyperproliferative effect Effects 0.000 abstract 1
230000001613 neoplastic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Hematology (AREA)
Oncology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Obesity (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO971934A 1996-05-23 1997-04-25 Flourinerte vitamin D3 -analoger NO971934L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US1818796P	1996-05-23	1996-05-23

Publications (2)

Publication Number	Publication Date
NO971934D0 NO971934D0 (no)	1997-04-25
NO971934L true NO971934L (no)	1997-11-24

Family

ID=21786696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO971934A NO971934L (no)	1996-05-23	1997-04-25	Flourinerte vitamin D3 -analoger

Country Status (30)

Country	Link
US (1)	US5888994A (de)
EP (1)	EP0808831B1 (de)
JP (1)	JP2858571B2 (de)
KR (1)	KR100237523B1 (de)
CN (1)	CN1081184C (de)
AR (1)	AR007240A1 (de)
AT (1)	ATE195514T1 (de)
AU (1)	AU720098B2 (de)
BR (1)	BR9703373A (de)
CA (1)	CA2204478C (de)
CO (1)	CO4840512A1 (de)
CZ (1)	CZ157997A3 (de)
DE (1)	DE69702812T2 (de)
DK (1)	DK0808831T3 (de)
ES (1)	ES2150719T3 (de)
GR (1)	GR3034832T3 (de)
HR (1)	HRP970274A2 (de)
HU (1)	HUP9700927A3 (de)
IL (1)	IL120842A0 (de)
MA (1)	MA24345A1 (de)
NO (1)	NO971934L (de)
NZ (1)	NZ314838A (de)
PL (1)	PL320131A1 (de)
PT (1)	PT808831E (de)
SG (1)	SG50831A1 (de)
TR (1)	TR199700418A3 (de)
TW (1)	TW374762B (de)
UY (1)	UY24563A1 (de)
YU (1)	YU19997A (de)
ZA (1)	ZA974334B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO971934L (no) *	1996-05-23	1997-11-24	Hoffmann La Roche	Flourinerte vitamin D3 -analoger
EP0981514B1 (de) *	1997-05-16	2006-04-05	Woman & Infants Hospital	3-epi-vitamin d2 verbindungen und ihre anwendungen
CA2289209C (en)	1997-05-16	2006-07-25	Women & Infants Hospital	Cyclic ether vitamin d3 compounds, 1.alpha. (oh) 3-epi-vitamin d3 compounds and uses thereof
CA2303248A1 (en) *	1997-09-08	1999-03-18	F. Hoffmann-La Roche Ag	1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
WO2000051554A2 (en) *	1999-03-05	2000-09-08	Johns Hopkins University	Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound
US7148211B2 (en) *	2002-09-18	2006-12-12	Genzyme Corporation	Formulation for lipophilic agents
CA2586679A1 (en)	2004-11-12	2006-05-18	Bioxell Spa	Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
SI1993559T1 (sl)	2006-02-03	2017-01-31	Opko Renal, Llc	Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3
PT3357496T (pt)	2006-06-21	2020-05-12	Opko Ireland Global Holdings Ltd	Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d
KR20190141269A (ko)	2007-04-25	2019-12-23	사이토크로마 인코포레이티드	비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
CN101668532B (zh)	2007-04-25	2014-08-20	赛特克罗公司	治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的组合物及其相应的制药用途
CA2797537C (en)	2010-03-29	2021-11-23	Cytochroma Inc.	Use of 25-hydroxyvitamin d compound for reducing parathyroid levels
WO2012065050A1 (en)	2010-11-12	2012-05-18	Wisconsin Alumni Research Foundation	22-haloacetoxy-homopregnacalciferol analogs and their uses
KR101847947B1 (ko)	2013-03-15	2018-05-28	옵코 아이피 홀딩스 Ⅱ 인코포레이티드	안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en)	2014-08-07	2019-03-05	Opko Ireland Global Holdings, Ltd.	Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
EP4596045A3 (de)	2016-03-28	2025-10-15	EirGen Pharma Ltd.	Verfahren zur behandlung von vitamin d

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5039671A (en) *	1984-12-19	1991-08-13	Hoffmann-La Roche Inc.	Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
US5145846A (en) *	1988-01-20	1992-09-08	Hoffmann-La Roche Inc.	Vitamin D3 analogs
GB9007236D0 (en) *	1990-03-30	1990-05-30	Leo Pharm Prod Ltd	Chemical compounds
GB9017890D0 (en) *	1990-08-15	1990-09-26	Leo Pharm Prod Ltd	Chemical compounds i
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) *	1991-08-27	1993-05-11	Daikin Industries, Ltd.	Vitamin d3 analogues
US5200536A (en) *	1992-02-10	1993-04-06	Daikin Industries Ltd.	Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) *	1992-03-26	1992-05-06	Leo Pharm Prod Ltd	Chemical compounds
ATE141914T1 (de) *	1992-05-20	1996-09-15	Hoffmann La Roche	Fluorierte analoge vitamins d3
CA2096105A1 (en) *	1992-10-07	1994-04-08	Enrico Giuseppe Baggiolini (Deceased)	Vitamin d3 fluorinated analogs
TW267161B (de) *	1992-11-20	1996-01-01	Hoffmann La Roche
US5428029A (en) *	1993-11-24	1995-06-27	Hoffmann-La Roche Inc.	Vitamin D3 fluorinated analogs
US5384314B1 (en) *	1994-03-11	1997-08-05	Hoffmann La Roche	1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) *	1996-05-23	1997-11-24	Hoffmann La Roche	Flourinerte vitamin D3 -analoger

1997
- 1997-04-25 NO NO971934A patent/NO971934L/no unknown
- 1997-04-28 TW TW086105570A patent/TW374762B/zh active
- 1997-05-05 CA CA002204478A patent/CA2204478C/en not_active Expired - Fee Related
- 1997-05-12 SG SG1997001491A patent/SG50831A1/en unknown
- 1997-05-14 DE DE69702812T patent/DE69702812T2/de not_active Expired - Fee Related
- 1997-05-14 PT PT97107848T patent/PT808831E/pt unknown
- 1997-05-14 DK DK97107848T patent/DK0808831T3/da active
- 1997-05-14 EP EP97107848A patent/EP0808831B1/de not_active Expired - Lifetime
- 1997-05-14 AT AT97107848T patent/ATE195514T1/de not_active IP Right Cessation
- 1997-05-14 ES ES97107848T patent/ES2150719T3/es not_active Expired - Lifetime
- 1997-05-16 IL IL12084297A patent/IL120842A0/xx unknown
- 1997-05-16 NZ NZ314838A patent/NZ314838A/en unknown
- 1997-05-16 US US08/857,883 patent/US5888994A/en not_active Expired - Fee Related
- 1997-05-19 ZA ZA9704334A patent/ZA974334B/xx unknown
- 1997-05-20 HR HR60/018,187A patent/HRP970274A2/xx not_active Application Discontinuation
- 1997-05-20 YU YU19997A patent/YU19997A/sh unknown
- 1997-05-20 JP JP9129238A patent/JP2858571B2/ja not_active Expired - Fee Related
- 1997-05-21 CO CO97027698A patent/CO4840512A1/es unknown
- 1997-05-21 HU HU9700927A patent/HUP9700927A3/hu unknown
- 1997-05-21 MA MA24629A patent/MA24345A1/fr unknown
- 1997-05-21 AR ARP970102157A patent/AR007240A1/es active IP Right Grant
- 1997-05-22 CZ CZ971579A patent/CZ157997A3/cs unknown
- 1997-05-22 AU AU23572/97A patent/AU720098B2/en not_active Ceased
- 1997-05-22 KR KR1019970019921A patent/KR100237523B1/ko not_active Expired - Fee Related
- 1997-05-22 UY UY24563A patent/UY24563A1/es not_active Application Discontinuation
- 1997-05-22 PL PL97320131A patent/PL320131A1/xx unknown
- 1997-05-23 TR TR97/00418A patent/TR199700418A3/tr unknown
- 1997-05-23 CN CN97111050A patent/CN1081184C/zh not_active Expired - Fee Related
- 1997-05-23 BR BR9703373A patent/BR9703373A/pt not_active Application Discontinuation
2000
- 2000-11-13 GR GR20000402519T patent/GR3034832T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ314838A (en)	1998-01-26
MA24345A1 (fr)	1998-07-01
CO4840512A1 (es)	1999-09-27
ES2150719T3 (es)	2000-12-01
EP0808831B1 (de)	2000-08-16
GR3034832T3 (en)	2001-02-28
AU720098B2 (en)	2000-05-25
AR007240A1 (es)	1999-10-27
BR9703373A (pt)	1998-09-15
SG50831A1 (en)	1998-07-20
EP0808831A2 (de)	1997-11-26
CN1081184C (zh)	2002-03-20
EP0808831A3 (de)	1999-02-03
UY24563A1 (es)	2000-12-29
CA2204478A1 (en)	1997-11-23
HRP970274A2 (en)	1998-04-30
JP2858571B2 (ja)	1999-02-17
HU9700927D0 (en)	1997-07-28
CN1169425A (zh)	1998-01-07
DE69702812T2 (de)	2001-01-25
ATE195514T1 (de)	2000-09-15
ZA974334B (en)	1997-11-24
DE69702812D1 (de)	2000-09-21
KR970074763A (ko)	1997-12-10
US5888994A (en)	1999-03-30
YU19997A (sh)	1999-07-28
HUP9700927A2 (hu)	1998-01-28
AU2357297A (en)	1997-11-27
TR199700418A2 (xx)	1997-12-21
KR100237523B1 (ko)	2000-01-15
HUP9700927A3 (en)	1999-07-28
IL120842A0 (en)	1997-09-30
MX9703776A (es)	1998-06-30
TR199700418A3 (tr)	1997-12-21
TW374762B (en)	1999-11-21
DK0808831T3 (da)	2001-01-02
CA2204478C (en)	2006-11-21
PL320131A1 (en)	1997-11-24
NO971934D0 (no)	1997-04-25
CZ157997A3 (en)	1997-12-17
JPH1045712A (ja)	1998-02-17
PT808831E (pt)	2000-12-29

Publication	Publication Date	Title
NO971934L (no)	1997-11-24	Flourinerte vitamin D3 -analoger
NO972304L (no)	1997-11-24	Vitamin D3-analoger
GB2102287B (en)	1985-02-27	Use of aromatase-inhibitors with antiandrogens for treatment of prostatic hyperplasia.
HU9301361D0 (en)	1993-09-28	Method for producing 4-aryl-piperazines and 4-aryl-piperidines
NO983266L (no)	1998-09-15	Distribuert Behandling
ZA899251B (en)	1990-09-26	Hypocholesterolemic and antiatherosclerotic uses of bis(3,5-ditertiary-butyl-4-hydroxyphenylthio)methane
DE69409148D1 (de)	1998-04-30	Verfahren zur Herstellung von Wasserstoffperoxid
ID24308A (id)	2000-07-13	Plasma darah yang dapat diaplikasikan secara universal
ATE141914T1 (de)	1996-09-15	Fluorierte analoge vitamins d3
MX9703024A (es)	1997-10-31	Cristalizacion de levobupivacaina y sus analogos.
NO934197D0 (no)	1993-11-19	Vitamin D-3-analoger
NO973366L (no)	1997-07-21	Fremgangsmåte for behandling av multippel sklerose
DK0520372T3 (da)	1997-05-12	Inositol-phosphat-analoger som calciumantagonistiske stoffer
ECSP972130A (es)	1998-07-23	Analogos de vitamina d3 - fluorinados
GR3034688T3 (en)	2001-01-31	Use of 6,7-substituted-2-aminotetralines for preparing pharmaceutical compositions useful for the treatment of septic shock, and antipyretic and antiinflammatory pharmaceutical compositions
MX9708190A (es)	1998-04-30	Metodo para tratar dioxido de cloro.
NO995132L (no)	1999-10-21	Fremgangsmåte for reduksjon av fibrinogen
FI934442A7 (fi)	1993-10-29	Katalysoitu menetelmä hypokloriitti-ionien hajottamiseksi
ATE174965T1 (de)	1999-01-15	Verfahren zur herstellung von halogenierten hydroxyphenylessigsäuren
KR960700729A (ko)	1996-02-24	26,26,26,27,27,27-헥사플루오로-1 알파, 25-디히드록시콜레칼시페롤의 칼슘 대사 장애의 치료 용도(Use of 26,26,26,27,27,27-Hexafluoro-1alpha, 25-Dihydroxycholecalciferol for the treatment of Calcium Metabolism Disorders)
MD259C2 (ro)	1995-12-31	Metodă de tratament al maladiei ulceroase a duodenului, complicată cu stenoză piloroduodenală
IT1244888B (it)	1994-09-13	Procedimento per la sintesi di composti aromatici fluorurati
RU2072690C1 (ru)	1997-01-27	Штамм бактерий morganella morganii - продуцент термолабильного энтеротоксина
ECSP972129A (es)	1998-07-23	Analogos de vitamina d3
GR960100116A (el)	1996-12-31	Μεθοδος παρασκευης 1-κυκλοπροπυλο-6-φλουορο-1,4-διυδρο-7-[(1s,4s)-5-μεθυλο-2,5-διαζαβικυκλο[2.2.1]-επτ-2-υλο] -4-οξο-3-κουινολινοκαρβοξυλικο οξυ και αλατα αυτων.