NO976044L - Meioseregulerende forbindelser - Google Patents

Meioseregulerende forbindelser

Info

Publication number
NO976044L
NO976044L NO976044A NO976044A NO976044L NO 976044 L NO976044 L NO 976044L NO 976044 A NO976044 A NO 976044A NO 976044 A NO976044 A NO 976044A NO 976044 L NO976044 L NO 976044L
Authority
NO
Norway
Prior art keywords
meios
regulating compounds
regulating
compounds
meios regulating
Prior art date
Application number
NO976044A
Other languages
English (en)
Other versions
NO314231B1 (no
NO976044D0 (no
Inventor
Frederik Groenvald
Peter Faarup
Erling Guddal
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO976044D0 publication Critical patent/NO976044D0/no
Publication of NO976044L publication Critical patent/NO976044L/no
Publication of NO314231B1 publication Critical patent/NO314231B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19976044A 1995-06-23 1997-12-22 Meioseregulerende forbindelser og anvendelse derav til fremstilling av medikamenter NO314231B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK73095 1995-06-23
DK72895 1995-06-23
DK146195 1995-12-22
PCT/DK1996/000273 WO1997000884A1 (en) 1995-06-23 1996-06-21 Meiosis regulating compounds

Publications (3)

Publication Number Publication Date
NO976044D0 NO976044D0 (no) 1997-12-22
NO976044L true NO976044L (no) 1998-02-20
NO314231B1 NO314231B1 (no) 2003-02-17

Family

ID=27220892

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19976044A NO314231B1 (no) 1995-06-23 1997-12-22 Meioseregulerende forbindelser og anvendelse derav til fremstilling av medikamenter

Country Status (18)

Country Link
EP (1) EP0857173B1 (no)
JP (1) JPH11507929A (no)
KR (1) KR19990028366A (no)
CN (1) CN1191543A (no)
AR (1) AR003441A1 (no)
AT (1) ATE254628T1 (no)
AU (1) AU718246B2 (no)
BR (1) BR9608968A (no)
CA (1) CA2224866A1 (no)
CZ (1) CZ408097A3 (no)
DE (1) DE69630802T2 (no)
HU (1) HUP9900454A3 (no)
IL (1) IL122609A0 (no)
NO (1) NO314231B1 (no)
PL (1) PL185622B1 (no)
RU (1) RU2182909C2 (no)
TW (1) TW474943B (no)
WO (1) WO1997000884A1 (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998052965A1 (en) * 1997-05-16 1998-11-26 Akzo Nobel N.V. 20-ARALKYL-5α-PREGNANE DERIVATIVES
TR199902873T2 (xx) * 1997-06-04 2000-04-21 Akzo Nobel N.V. Miyozun mod�lasyonu i�in 17�-aliloksi(tiyo)alkil-androstan t�revleri.
JP2001526293A (ja) * 1997-12-18 2001-12-18 アクゾ・ノベル・エヌ・ベー １７β−アリール（アリールメチル）オキシ（チオ）アルキル−アンドロスタン誘導体
KR20010043558A (ko) 1998-05-13 2001-05-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 감수분열 조절 화합물
EP0957108A1 (en) * 1998-05-14 1999-11-17 Schering Aktiengesellschaft Unsaturated cholestane derivatives, pharmaceutical compositions comprising them and use of these derivatives for the preparation of meiosis regulating medicaments
IL140216A0 (en) * 1998-06-19 2002-02-10 Novo Nordisk As Meiosis regulating compounds
US6528501B1 (en) 1998-12-11 2003-03-04 Akzo Nobel N.V. 22s-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
AU3118200A (en) * 1998-12-14 2000-07-03 Merck & Co., Inc. Hiv integrase inhibitors
CZ20012866A3 (cs) * 1999-02-10 2002-01-16 Schering Aktiengesellschaft Nenasycené cholestanové deriváty, farmaceutické kompozice obsahující tyto deriváty a pouľití těchto derivátů pro přípravu léčiv regulujících meiozu
AU2794000A (en) 1999-02-24 2000-09-14 Novo Nordisk A/S Treatment of infertility
CN1353617A (zh) * 1999-02-24 2002-06-12 诺沃挪第克公司 不孕症的治疗
CA2382908A1 (en) 1999-09-16 2001-03-22 Novo Nordisk A/S Composition for ivf
EP1127890A1 (en) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments
MXPA02007818A (es) * 2000-02-25 2002-10-23 Schering Ag Tasa de implantacion mejorada utilizando ff-mas.
EP1245572A1 (en) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol compounds, their use in the preparation of meiosis-regulating medicaments and method for their preparation
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
US8399441B2 (en) 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
CN102258004B (zh) * 2010-05-27 2013-07-17 中国科学院动物研究所 一种体外保存/培养卵母细胞以抑制卵母细胞生发泡破裂的方法
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
CA2848212C (en) 2011-09-08 2022-03-29 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
PT2968369T (pt) 2013-03-13 2018-12-05 Sage Therapeutics Inc Esteroides neuroativos e métodos para o seu uso
HRP20220112T1 (hr) 2013-12-24 2022-04-15 Virginia Commonwealth University Upotreba oksidacijskog sulfata kolesterola (ocs) za liječenje akutne insuficijencije jetre
US10259840B2 (en) 2014-06-18 2019-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
EA024619B1 (ru) * 2014-11-21 2016-10-31 Эльвин Гаджи оглы Керимли ФРАКСИНОСТЕРИН - 24β-ЭТИЛХОЛЕСТА-20-КАРБОКСИ-6(7),8(9)-ДИЕН 3β-ОЛА И ЕГО ПРОИЗВОДНОЕ
HUE071964T2 (hu) 2015-07-06 2025-10-28 Sage Therapeutics Inc Oxiszterolok és alkalmazási eljárásaik
CA2991311C (en) 2015-07-06 2025-05-06 Sage Therapeutics, Inc. OXYSTEROLS AND THEIR METHODS OF USE
EP3828194B1 (en) 2015-07-06 2025-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
SMT202200300T1 (it) 2016-04-01 2022-09-14 Sage Therapeutics Inc Ossisteroli e relativi metodi d'uso
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
ES2884071T3 (es) 2016-07-07 2021-12-10 Sage Therapeutics Inc 24-hidroxiesteroles sustituidos en 11 para el tratamiento de afecciones relacionadas con NMDA
EP3494125B1 (en) 2016-08-02 2022-06-22 Virginia Commonwealth University Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide
ES2935057T3 (es) 2016-09-30 2023-03-01 Sage Therapeutics Inc C7 oxisteroles sustituidos y estos compuestos para su uso como moduladores de la NMDA
RU2019115113A (ru) 2016-10-18 2020-11-24 Сейдж Терапьютикс, Инк. Оксистеролы и способы их применения
KR20230051723A (ko) 2016-10-18 2023-04-18 세이지 테라퓨틱스, 인크. 옥시스테롤 및 그의 사용 방법
CN112430251A (zh) * 2020-11-23 2021-03-02 广州瀚信通信科技股份有限公司 一种治疗白内障的化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols

Also Published As

Publication number Publication date
AR003441A1 (es) 1998-08-05
AU6122796A (en) 1997-01-22
WO1997000884A1 (en) 1997-01-09
IL122609A0 (en) 1998-08-16
TW474943B (en) 2002-02-01
NO314231B1 (no) 2003-02-17
CA2224866A1 (en) 1997-01-09
DE69630802D1 (de) 2003-12-24
RU2182909C2 (ru) 2002-05-27
BR9608968A (pt) 1999-06-29
PL324219A1 (en) 1998-05-11
AU718246B2 (en) 2000-04-13
CN1191543A (zh) 1998-08-26
HUP9900454A3 (en) 1999-11-29
DE69630802T2 (de) 2004-08-12
EP0857173A1 (en) 1998-08-12
MX9800123A (es) 1998-03-29
JPH11507929A (ja) 1999-07-13
HUP9900454A2 (hu) 1999-06-28
CZ408097A3 (cs) 1998-06-17
KR19990028366A (ko) 1999-04-15
PL185622B1 (pl) 2003-06-30
EP0857173B1 (en) 2003-11-19
ATE254628T1 (de) 2003-12-15
NO976044D0 (no) 1997-12-22

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