NO980574L - (1S,2S)-1-(4-Hydroksyfenyl)-2-(4-hydroksy-4-fenylpiperidin-1-yl)-1-propanol-metansulfonattrihydrat - Google Patents

(1S,2S)-1-(4-Hydroksyfenyl)-2-(4-hydroksy-4-fenylpiperidin-1-yl)-1-propanol-metansulfonattrihydrat

Info

Publication number: NO980574L
Authority: NO; Norway
Prior art keywords: phenylpiperidine; hydroxyphenyl; hydroxy; propanol methanesulfonate; methanesulfonate
Prior art date: 1995-08-11

Application number

NO980574A

Other languages

English (en)

Other versions

NO980574D0 (no

NO310458B1 (no

Inventor

Marta Maria Andino

Terry Gene Sinay

Eugene Fred Fiese

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-11

Filing date

1998-02-10

Publication date

1998-02-10

1998-02-10 Application filed by Pfizer filed Critical Pfizer

1998-02-10 Publication of NO980574D0 publication Critical patent/NO980574D0/no

1998-02-10 Publication of NO980574L publication Critical patent/NO980574L/no

2001-07-09 Publication of NO310458B1 publication Critical patent/NO310458B1/no

Links

JXMMHWDXGROLEN-OXJNMPFZSA-N [(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)propyl] methanesulfonate Chemical compound C1([C@H](OS(C)(=O)=O)[C@H](C)N2CCC(O)(CC2)C=2C=CC=CC=2)=CC=C(O)C=C1 JXMMHWDXGROLEN-OXJNMPFZSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

NO19980574A 1995-08-11 1998-02-10 (1S,2S)-1-(4-hydroksyfenyl)-2-(4-hydroksy-4-fenylpiperidin-1- yl)-1-propanol-metansulfonattrihydrat, anvendelse derav samtfarmasöytisk preparat NO310458B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US223895P	1995-08-11	1995-08-11
PCT/IB1996/000592 WO1997007098A1 (en)	1995-08-11	1996-06-20	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanolmethanesulfonate trihydrate

Publications (3)

Publication Number	Publication Date
NO980574D0 NO980574D0 (no)	1998-02-10
NO980574L true NO980574L (no)	1998-02-10
NO310458B1 NO310458B1 (no)	2001-07-09

Family

ID=21699847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19980574A NO310458B1 (no)	1995-08-11	1998-02-10	(1S,2S)-1-(4-hydroksyfenyl)-2-(4-hydroksy-4-fenylpiperidin-1- yl)-1-propanol-metansulfonattrihydrat, anvendelse derav samtfarmasöytisk preparat

Country Status (41)

Country	Link
US (1)	US6008233A (no)
EP (1)	EP0843661B1 (no)
JP (1)	JP3099072B2 (no)
KR (1)	KR100291882B1 (no)
CN (2)	CN1615861A (no)
AP (1)	AP755A (no)
AR (1)	AR004676A1 (no)
AT (1)	ATE215072T1 (no)
AU (1)	AU710984B2 (no)
BG (1)	BG63678B1 (no)
BR (1)	BR9610766A (no)
CA (1)	CA2228752C (no)
CO (1)	CO4750830A1 (no)
CZ (1)	CZ296236B6 (no)
DE (1)	DE69620191T2 (no)
DK (1)	DK0843661T3 (no)
DZ (1)	DZ2083A1 (no)
ES (1)	ES2170857T3 (no)
GT (1)	GT199600051A (no)
HR (1)	HRP960372B1 (no)
HU (1)	HUP9802862A3 (no)
IL (1)	IL122649A (no)
IS (1)	IS1945B (no)
MA (1)	MA23957A1 (no)
NO (1)	NO310458B1 (no)
NZ (1)	NZ309134A (no)
OA (1)	OA10664A (no)
PE (1)	PE4898A1 (no)
PL (1)	PL185603B1 (no)
PT (1)	PT843661E (no)
RO (1)	RO120134B1 (no)
RS (1)	RS49521B (no)
RU (1)	RU2140910C1 (no)
SA (1)	SA96170171B1 (no)
SK (1)	SK284209B6 (no)
TN (1)	TNSN96104A1 (no)
TR (1)	TR199800208T1 (no)
TW (1)	TW495502B (no)
UA (1)	UA59341C2 (no)
WO (1)	WO1997007098A1 (no)
ZA (1)	ZA966760B (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100224961B1 (ko) *	1994-08-18	1999-10-15	디. 제이. 우드	신경보호성 3-(피페리디닐-1)-크로만-4,7-디올 및 1-(4-하이드로페닐)-2-(피페리디닐-1)-알칸올 유도체
NZ309134A (en) *	1995-08-11	1999-09-29	Pfizer	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1- propranolmethanesulfonate trihydrate
GB9820405D0 (en)	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process
EP1182193A4 (en) *	1999-04-09	2002-09-11	Mochida Pharm Co Ltd	REMEDIES FOR NEUROGENIC PAIN
GB9920919D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel compound
GB9920917D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel process
US6620830B2 (en) *	2000-04-21	2003-09-16	Pfizer, Inc.	Thyroid receptor ligands
YU27801A (sh) *	2000-04-28	2003-04-30	Pfizer Products Inc.	Postupak za dobijanje trihidrata mezilatne soli 1-(4- hidroksifenil)-2-(4-hidroksi-4-fenilpiperidin-1-il)-1-propanola i korisnih intermedijera
YU27701A (sh) *	2000-04-28	2003-04-30	Pfizer Products Inc.	Postupak za dobijanje trihidrata mezilatne soli 1-(4- hidroksifenil)-2-(4-hidroksi-4-fenilpiperidin-1-il)1-propanola
PL363365A1 (en)	2000-08-16	2004-11-15	Pharmacia & Upjohn Company	Compounds for the treatment of addictive disorders
EP1186303A3 (en) *	2000-09-06	2003-12-10	Pfizer Products Inc.	Pharmaceutical combinations, for the treatment of stroke and traumatic brain injury, containing a neutrophil inhibiting factor and an selective NMDA-NR2B receptor antagonist
EP1674087A1 (en)	2000-10-02	2006-06-28	Pfizer Products Inc.	Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
IL145584A0 (en)	2000-10-02	2002-06-30	Pfizer Prod Inc	Nmda nr2b antagonists for treatment
UA73619C2 (en) *	2000-12-13	2005-08-15	Pfizer Prod Inc	Stable pharmaceutical compositions of nmda receptor agonist (variants) and method of treatment
IL161308A0 (en) *	2001-10-19	2004-09-27	Toyama Chemical Co Ltd	Alkyl ether derivatives or their salts
KR100517638B1 (ko)	2002-04-08	2005-09-28	주식회사 엘지생명과학	게미플록사신 산염의 새로운 제조방법
RU2416603C9 (ru)	2005-10-25	2012-06-20	Сионоги Энд Ко., Лтд.	Производные аминодигидротиазина
EP2151435A4 (en)	2007-04-24	2011-09-14	Shionogi & Co	PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALZHEIMER'S DISEASE
EP2147914B1 (en)	2007-04-24	2014-06-04	Shionogi&Co., Ltd.	Aminodihydrothiazine derivatives substituted with cyclic groups
WO2009151098A1 (ja)	2008-06-13	2009-12-17	塩野義製薬株式会社	βセクレターゼ阻害作用を有する含硫黄複素環誘導体
CN102186841A (zh)	2008-10-22	2011-09-14	盐野义制药株式会社	具有bace1抑制活性的2-氨基嘧啶-4-酮及2-氨基吡啶衍生物
TWI488852B (zh)	2009-12-11	2015-06-21	Shionogi & Co	衍生物
JP5766198B2 (ja)	2010-10-29	2015-08-19	塩野義製薬株式会社	縮合アミノジヒドロピリミジン誘導体
JP5816630B2 (ja)	2010-10-29	2015-11-18	塩野義製薬株式会社	ナフチリジン誘導体
TW201247635A (en)	2011-04-26	2012-12-01	Shionogi & Co	Oxazine derivatives and a pharmaceutical composition for inhibiting BAC1 containing them
EP2912035A4 (en)	2012-10-24	2016-06-15	Shionogi & Co	DERIVATIVES OF DIHYDROOXAZINE OR OXAZEPINE HAVING BACE1 INHIBITING ACTIVITY
AU2015317886A1 (en)	2014-09-15	2017-03-09	Rugen Holdings (Cayman) Limited	Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists
EP3197440A4 (en) *	2014-09-22	2018-04-18	Rugen Holdings (Cayman) Limited	Treatment of anxiety disorders and autism spectrum disorders
EP3253761A4 (en)	2015-02-04	2018-06-20	Rugen Holdings (Cayman) Limited	3,3-difluoro-piperidine derivatives as nr2b nmda receptor antagonists
BR112017025023B1 (pt)	2015-06-01	2024-01-30	Rugen Holdings (Cayman) Limited	Compostos heterocíclicos de carbamato de 3,3-difluoropiperidina, seu uso como antagonistas do receptor nmda nr2b e composição farmacêutica que os compreende
WO2018098128A1 (en)	2016-11-22	2018-05-31	Rugen Holdings (Cayman) Limited	Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disorders

Family Cites Families (4)

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Publication number	Priority date	Publication date	Assignee	Title
SK232890A3 (en) *	1989-05-17	1998-11-04	Pfizer	2-piperidino and 2-pyrrolidino-1-alkanols derivatives and preparation method thereof
US5272160A (en) *	1989-05-17	1993-12-21	Pfizer Inc	2-piperidino-1-alkanol derivatives as antiischemic agents
KR100224961B1 (ko) *	1994-08-18	1999-10-15	디. 제이. 우드	신경보호성 3-(피페리디닐-1)-크로만-4,7-디올 및 1-(4-하이드로페닐)-2-(피페리디닐-1)-알칸올 유도체
NZ309134A (en) *	1995-08-11	1999-09-29	Pfizer	(1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1- propranolmethanesulfonate trihydrate

1996
- 1996-06-20 NZ NZ309134A patent/NZ309134A/en unknown
- 1996-06-20 ES ES96916266T patent/ES2170857T3/es not_active Expired - Lifetime
- 1996-06-20 TR TR1998/00208T patent/TR199800208T1/xx unknown
- 1996-06-20 PL PL96325050A patent/PL185603B1/pl not_active IP Right Cessation
- 1996-06-20 DE DE69620191T patent/DE69620191T2/de not_active Expired - Fee Related
- 1996-06-20 US US09/011,426 patent/US6008233A/en not_active Expired - Fee Related
- 1996-06-20 HU HU9802862A patent/HUP9802862A3/hu unknown
- 1996-06-20 CN CNA031584969A patent/CN1615861A/zh active Pending
- 1996-06-20 EP EP96916266A patent/EP0843661B1/en not_active Expired - Lifetime
- 1996-06-20 IL IL12264996A patent/IL122649A/xx not_active IP Right Cessation
- 1996-06-20 WO PCT/IB1996/000592 patent/WO1997007098A1/en not_active Ceased
- 1996-06-20 AT AT96916266T patent/ATE215072T1/de not_active IP Right Cessation
- 1996-06-20 KR KR1019980700989A patent/KR100291882B1/ko not_active Expired - Fee Related
- 1996-06-20 DK DK96916266T patent/DK0843661T3/da active
- 1996-06-20 CN CN96195649A patent/CN1198739A/zh active Pending
- 1996-06-20 CZ CZ0039098A patent/CZ296236B6/cs not_active IP Right Cessation
- 1996-06-20 RU RU98102116A patent/RU2140910C1/ru not_active IP Right Cessation
- 1996-06-20 BR BR9610766A patent/BR9610766A/pt not_active Application Discontinuation
- 1996-06-20 UA UA98020673A patent/UA59341C2/uk unknown
- 1996-06-20 AU AU59084/96A patent/AU710984B2/en not_active Ceased
- 1996-06-20 PT PT96916266T patent/PT843661E/pt unknown
- 1996-06-20 RO RO98-00231A patent/RO120134B1/ro unknown
- 1996-06-20 JP JP09509083A patent/JP3099072B2/ja not_active Expired - Fee Related
- 1996-06-20 CA CA002228752A patent/CA2228752C/en not_active Expired - Fee Related
- 1996-06-20 SK SK166-98A patent/SK284209B6/sk unknown
- 1996-06-24 TW TW085107571A patent/TW495502B/zh not_active IP Right Cessation
- 1996-07-04 GT GT199600051A patent/GT199600051A/es unknown
- 1996-07-23 SA SA96170171A patent/SA96170171B1/ar unknown
- 1996-08-06 PE PE1996000587A patent/PE4898A1/es not_active Application Discontinuation
- 1996-08-07 DZ DZ960127A patent/DZ2083A1/fr active
- 1996-08-07 MA MA24335A patent/MA23957A1/fr unknown
- 1996-08-07 AR ARP960103904A patent/AR004676A1/es unknown
- 1996-08-07 TN TNTNSN96104A patent/TNSN96104A1/fr unknown
- 1996-08-08 AP APAP/P/1996/000856A patent/AP755A/en active
- 1996-08-08 ZA ZA9606760A patent/ZA966760B/xx unknown
- 1996-08-09 RS YU46196A patent/RS49521B/sr unknown
- 1996-08-09 CO CO96042164A patent/CO4750830A1/es unknown
- 1996-08-09 HR HR960372A patent/HRP960372B1/xx not_active IP Right Cessation
1997
- 1997-12-30 IS IS4643A patent/IS1945B/is unknown
1998
- 1998-02-10 NO NO19980574A patent/NO310458B1/no unknown
- 1998-02-10 OA OA9800021A patent/OA10664A/en unknown
- 1998-02-27 BG BG102289A patent/BG63678B1/bg unknown

Also Published As

Publication number	Publication date
HRP960372A2 (en)	1998-04-30
PE4898A1 (es)	1998-03-16
KR19990036321A (ko)	1999-05-25
HUP9802862A2 (hu)	1999-04-28
IS4643A (is)	1997-12-30
OA10664A (en)	2000-11-06
BG63678B1 (bg)	2002-09-30
EP0843661B1 (en)	2002-03-27
NZ309134A (en)	1999-09-29
NO980574D0 (no)	1998-02-10
ATE215072T1 (de)	2002-04-15
JPH10510552A (ja)	1998-10-13
DK0843661T3 (da)	2002-07-22
BR9610766A (pt)	1999-07-13
RU2140910C1 (ru)	1999-11-10
NO310458B1 (no)	2001-07-09
IS1945B (is)	2004-08-13
SA96170171B1 (ar)	2006-05-20
DE69620191T2 (de)	2002-07-18
SK16698A3 (en)	1999-06-11
AP755A (en)	1999-08-02
MX9801149A (es)	1998-05-31
DZ2083A1 (fr)	2002-10-23
AR004676A1 (es)	1999-03-10
AU5908496A (en)	1997-03-12
RO120134B1 (ro)	2005-09-30
CZ39098A3 (cs)	1999-02-17
YU46196A (sh)	1999-07-28
CA2228752A1 (en)	1997-02-27
CA2228752C (en)	2002-12-10
GT199600051A (es)	1997-12-26
JP3099072B2 (ja)	2000-10-16
ZA966760B (en)	1998-02-09
KR100291882B1 (ko)	2001-10-26
DE69620191D1 (de)	2002-05-02
PT843661E (pt)	2002-07-31
WO1997007098A1 (en)	1997-02-27
RS49521B (sr)	2006-10-27
SK284209B6 (en)	2004-11-03
TW495502B (en)	2002-07-21
UA59341C2 (uk)	2003-09-15
ES2170857T3 (es)	2002-08-16
AP9600856A0 (en)	1996-10-31
CN1198739A (zh)	1998-11-11
CO4750830A1 (es)	1999-03-31
HUP9802862A3 (en)	1999-05-28
HRP960372B1 (en)	2003-04-30
TR199800208T1 (no)	1998-05-21
IL122649A0 (en)	1998-08-16
AU710984B2 (en)	1999-10-07
PL325050A1 (en)	1998-07-06
EP0843661A1 (en)	1998-05-27
US6008233A (en)	1999-12-28
TNSN96104A1 (fr)	2005-03-15
CN1615861A (zh)	2005-05-18
MA23957A1 (fr)	1997-04-01
CZ296236B6 (cs)	2006-02-15
IL122649A (en)	2001-08-26
PL185603B1 (pl)	2003-06-30
BG102289A (en)	1998-09-30

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