NO990484L - Aminosyreester inneholdende azol antisoppmiddel - Google Patents

Aminosyreester inneholdende azol antisoppmiddel

Info

Publication number: NO990484L
Authority: NO; Norway
Prior art keywords: amino acid; acid ester; antifungal agent; ester containing; azole antifungal
Prior art date: 1997-02-11

Application number

NO990484A

Other languages

English (en)

Other versions

NO316668B1 (no

NO990484D0 (no

Inventor

Lieven Meerpoel

Jan Heeres

Robert Jozef Maria Hendrickx

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-02-11

Filing date

1999-02-02

Publication date

1999-10-11

1999-02-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1999-02-02 Publication of NO990484D0 publication Critical patent/NO990484D0/no

1999-10-11 Publication of NO990484L publication Critical patent/NO990484L/no

2004-03-29 Publication of NO316668B1 publication Critical patent/NO316668B1/no

Links

KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title abstract 4
229940121375 antifungal agent Drugs 0.000 title abstract 2
-1 Amino acid ester Chemical class 0.000 title 1
239000003429 antifungal agent Substances 0.000 title 1
WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical class C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 abstract 1
125000000815 N-oxide group Chemical group 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO19990484A 1997-02-11 1999-02-02 Aminosyreesterinneholdende azoler, deres mellomprodukter og anvendelse av forbindelsene, samt farmasoytiske blandinger NO316668B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP97200374		1997-02-11
EP97203228		1997-10-15
PCT/EP1998/000646 WO1998034934A1 (en)	1997-02-11	1998-02-03	Amino acid ester containing azole antifungals

Publications (3)

Publication Number	Publication Date
NO990484D0 NO990484D0 (no)	1999-02-02
NO990484L true NO990484L (no)	1999-10-11
NO316668B1 NO316668B1 (no)	2004-03-29

Family

ID=26146124

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19990484A NO316668B1 (no)	1997-02-11	1999-02-02	Aminosyreesterinneholdende azoler, deres mellomprodukter og anvendelse av forbindelsene, samt farmasoytiske blandinger

Country Status (31)

Country	Link
US (3)	US6262052B1 (no)
EP (1)	EP0958289B1 (no)
JP (1)	JP4347911B2 (no)
KR (1)	KR100509171B1 (no)
CN (1)	CN1238353C (no)
AT (1)	ATE270290T1 (no)
AU (1)	AU725302C (no)
BG (1)	BG63872B1 (no)
BR (1)	BR9809744A (no)
CA (1)	CA2262791C (no)
CZ (1)	CZ297197B6 (no)
DE (1)	DE69824834T2 (no)
DK (1)	DK0958289T3 (no)
EE (1)	EE03876B1 (no)
ES (1)	ES2224364T3 (no)
HU (1)	HU227744B1 (no)
ID (1)	ID21755A (no)
IL (2)	IL128513A (no)
MY (1)	MY129537A (no)
NO (1)	NO316668B1 (no)
NZ (1)	NZ334477A (no)
PL (1)	PL191152B1 (no)
PT (1)	PT958289E (no)
RU (1)	RU2197489C2 (no)
SI (1)	SI0958289T1 (no)
SK (1)	SK284910B6 (no)
TR (1)	TR199900584T2 (no)
TW (1)	TW495508B (no)
UA (1)	UA61919C2 (no)
WO (1)	WO1998034934A1 (no)
ZA (1)	ZA981079B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0957101A1 (en)	1998-05-14	1999-11-17	Janssen Pharmaceutica N.V.	Water soluble azoles as broad-spectrum antifungals
AU1915500A (en)	1998-11-20	2000-06-13	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
ES2194723T3 (es)	1999-05-04	2003-12-01	Janssen Pharmaceutica Nv	Eteres antifungicos.
WO2003052117A2 (en) *	2001-09-19	2003-06-26	Massachusetts Institute Of Technology	Methods and products related to non-viral transfection
ITMI20032020A1 (it)	2003-10-17	2005-04-18	Italfarmaco Spa	Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici
EP2571871B1 (en) *	2010-05-19	2017-06-21	Sandoz AG	Process for the preparation of chiral triazolones
US20170290333A1 (en)	2014-12-30	2017-10-12	Dow Agrosciences Llc	Picolinamide compounds with fungicidal activity
BR102019004480B1 (pt) *	2018-03-08	2023-03-28	Dow Agrosciences Llc	Picolinamidas como fungicidas
CN111138421A (zh) *	2019-12-26	2020-05-12	上海英诺富成生物科技有限公司	抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4267179A (en)	1978-06-23	1981-05-12	Janssen Pharmaceutica, N.V.	Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4791111A (en) *	1985-12-23	1988-12-13	Janssen Pharmaceutica, N.V.	[[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
US4916134A (en)	1987-03-25	1990-04-10	Janssen Pharmacuetica N.V.	4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]me]phenyl]-1-piperazinyl]phenyl]triazolones
CA1331757C (en)	1988-02-29	1994-08-30	Janssen Pharmaceutica Naamloze Vennootschap	5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
NZ233502A (en) *	1989-06-09	1991-11-26	Janssen Pharmaceutica Nv	4-(1,2,4-triazole- or imidazole-phenyl-substituted) -1-(1,3-dioxolan-4-ylmethoxyphenyl) piperazine derivatives; preparatory processes: fungicidal and antiviral compositions
HU221189B1 (en)	1992-03-18	2002-08-28	Janssen Pharmaceutica Nv	Itraconazole and saperconazole stereoisomers, their cyclodextrin complexes and pharmaceutical compositions containing them and process for producing them
PL181193B1 (pl)	1993-12-21	2001-06-29	Schering Corp	Nowe pochodne tetrahydrofuranowe o działaniu przeciwgrzybicznym, kompozycja farmaceutyczna do leczenia infekcji grzybiczych oraz sposób wytwarzania tych związków
NZ278882A (en) *	1994-01-24	1997-06-24	Janssen Pharmaceutica Nv	Piperazine-containing azole antifungal compounds
SK27097A3 (en) *	1995-06-02	1997-09-10	Schering Corp	Tetrahydrofuran antifungals
CA2224707A1 (en) *	1995-06-19	1997-01-03	Schering Corporation	Tetrahydrofuran antifungals

1998
- 1998-02-03 AU AU66207/98A patent/AU725302C/en not_active Expired
- 1998-02-03 SK SK1059-99A patent/SK284910B6/sk not_active IP Right Cessation
- 1998-02-03 NZ NZ334477A patent/NZ334477A/en not_active IP Right Cessation
- 1998-02-03 DK DK98908064T patent/DK0958289T3/da active
- 1998-02-03 DE DE69824834T patent/DE69824834T2/de not_active Expired - Lifetime
- 1998-02-03 JP JP53376398A patent/JP4347911B2/ja not_active Expired - Lifetime
- 1998-02-03 PT PT98908064T patent/PT958289E/pt unknown
- 1998-02-03 CN CNB988011352A patent/CN1238353C/zh not_active Expired - Lifetime
- 1998-02-03 EP EP98908064A patent/EP0958289B1/en not_active Expired - Lifetime
- 1998-02-03 SI SI9830687T patent/SI0958289T1/xx unknown
- 1998-02-03 HU HU0001050A patent/HU227744B1/hu unknown
- 1998-02-03 US US09/355,369 patent/US6262052B1/en not_active Expired - Lifetime
- 1998-02-03 ES ES98908064T patent/ES2224364T3/es not_active Expired - Lifetime
- 1998-02-03 BR BR9809744-0A patent/BR9809744A/pt not_active Application Discontinuation
- 1998-02-03 ID IDW990505A patent/ID21755A/id unknown
- 1998-02-03 WO PCT/EP1998/000646 patent/WO1998034934A1/en not_active Ceased
- 1998-02-03 IL IL12851398A patent/IL128513A/en not_active IP Right Cessation
- 1998-02-03 RU RU99106585/04A patent/RU2197489C2/ru active
- 1998-02-03 PL PL332008A patent/PL191152B1/pl unknown
- 1998-02-03 KR KR10-1999-7001983A patent/KR100509171B1/ko not_active Expired - Lifetime
- 1998-02-03 TR TR1999/00584T patent/TR199900584T2/xx unknown
- 1998-02-03 CZ CZ0283599A patent/CZ297197B6/cs not_active IP Right Cessation
- 1998-02-03 CA CA002262791A patent/CA2262791C/en not_active Expired - Lifetime
- 1998-02-03 EE EEP199900100A patent/EE03876B1/xx unknown
- 1998-02-03 AT AT98908064T patent/ATE270290T1/de active
- 1998-02-09 MY MYPI98000513A patent/MY129537A/en unknown
- 1998-02-09 TW TW087101662A patent/TW495508B/zh not_active IP Right Cessation
- 1998-02-10 ZA ZA9801079A patent/ZA981079B/xx unknown
- 1998-03-02 UA UA99020835A patent/UA61919C2/uk unknown
1999
- 1999-02-02 NO NO19990484A patent/NO316668B1/no not_active IP Right Cessation
- 1999-02-11 BG BG103171A patent/BG63872B1/bg unknown
2001
- 2001-05-04 US US09/848,989 patent/US6512116B2/en not_active Expired - Lifetime
2002
- 2002-04-23 IL IL149285A patent/IL149285A/en not_active IP Right Cessation
- 2002-11-15 US US10/298,038 patent/US6703506B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US20030158210A1 (en)	2003-08-21
PL191152B1 (pl)	2006-03-31
AU725302B2 (en)	2000-10-12
IL149285A0 (en)	2002-11-10
BG103171A (en)	1999-09-30
PL332008A1 (en)	1999-08-16
IL149285A (en)	2007-08-19
US6703506B2 (en)	2004-03-09
ES2224364T3 (es)	2005-03-01
CA2262791A1 (en)	1998-08-13
BR9809744A (pt)	2000-06-20
US20010039281A1 (en)	2001-11-08
UA61919C2 (uk)	2003-12-15
JP4347911B2 (ja)	2009-10-21
SK105999A3 (en)	2000-06-12
HUP0001050A2 (hu)	2001-04-28
CN1236366A (zh)	1999-11-24
RU2197489C2 (ru)	2003-01-27
DK0958289T3 (da)	2004-11-01
EP0958289A1 (en)	1999-11-24
TW495508B (en)	2002-07-21
ID21755A (id)	1999-07-22
CZ283599A3 (cs)	2000-02-16
SK284910B6 (sk)	2006-02-02
DE69824834D1 (de)	2004-08-05
US6262052B1 (en)	2001-07-17
NO316668B1 (no)	2004-03-29
ZA981079B (en)	1999-08-10
DE69824834T2 (de)	2005-07-21
NZ334477A (en)	2001-05-25
AU6620798A (en)	1998-08-26
CN1238353C (zh)	2006-01-25
BG63872B1 (bg)	2003-04-30
IL128513A0 (en)	2000-01-31
KR20000068526A (ko)	2000-11-25
CA2262791C (en)	2008-10-28
HU227744B1 (en)	2012-02-28
CZ297197B6 (cs)	2006-09-13
JP2001508080A (ja)	2001-06-19
NO990484D0 (no)	1999-02-02
MY129537A (en)	2007-04-30
PT958289E (pt)	2004-11-30
EP0958289B1 (en)	2004-06-30
IL128513A (en)	2002-11-10
EE9900100A (et)	1999-10-15
SI0958289T1 (en)	2004-12-31
EE03876B1 (et)	2002-10-15
TR199900584T2 (xx)	1999-10-21
WO1998034934A1 (en)	1998-08-13
HUP0001050A3 (en)	2001-07-30
AU725302C (en)	2001-08-23
US6512116B2 (en)	2003-01-28
ATE270290T1 (de)	2004-07-15
KR100509171B1 (ko)	2005-08-22

Legal Events

Date	Code	Title	Description
2018-02-12	MK1K	Patent expired

Publication	Publication Date	Title
ATE61050T1 (de)	1991-03-15	Pyridazinamine wirksam gegen viren.
DE69818649D1 (de)	2003-11-06	Mit durch n- oder c-verbundenen imidazole substituierten farnesyl-transferase inhibitorenden 1,8-annellierten chinolon-derivate
ES2062417T3 (es)	1994-12-16	Composiciones farmaceuticas de cimetidina.
BG60102B2 (bg)	1993-10-29	Метод за получаване на 5-флуор-2(((4-циклопропил- метокси-2-пиридинил)метил)тионил)-1н-бензимидазол
TR199903191T2 (xx)	2000-09-21	Vorikonazol i�eren ila� form�lasyonlar�.
NO920035L (no)	1992-07-01	Trifluormetylketon-derivater, og deres fremstilling og anvendelse
ATE73799T1 (de)	1992-04-15	Derivate des ((4-(4-(4-phenyl-1piperazinyl)phenoxymethyl>-1,3-dioxolan2yl>methyl>-1h-imidazol und 1h-1,2,4-triazol.
NO990484D0 (no)	1999-02-02	Aminosyreester inneholdende azol antisoppmiddel
SE0102055D0 (sv)	2001-06-08	New Compounds
TR200003322T2 (tr)	2001-02-21	Geniş spektrumlu mantar ilacı olarak kullanılan suda çözülebilen azoller
BR9807330A (pt)	2000-04-18	Agentes inibidores do progresso de pterìgio e recorrência pós-operatória do mesmo
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
HUP9901282A2 (hu)	1999-08-30	Karbamát- és karbonsavamidszármazék hatóanyagokat tartalmazó szinergetikus hatású fungicid keverékek és alkalmazásuk
RU94040865A (ru)	1996-08-10	Производные пептида и их терапевтически приемлемые соли, способ их получения, фармацевтическая и косметическая композиция с антивирусной активностью
TR199902055T2 (xx)	2000-07-21	Kinoksalindiyonlar.