NO992228L - 1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor - Google Patents

1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor

Info

Publication number: NO992228L
Authority: NO; Norway
Prior art keywords: hiv protease; phenylmethylcyclic; aminoindazol; protease inhibitor; urea suitable
Prior art date: 1996-11-08

Application number

NO992228A

Other languages

English (en)

Norwegian (no)

Other versions

NO992228D0 (no

Inventor

James David Rodgers

Iii Robert Frank Kaltenbach

Original Assignee

Du Pont Pharm Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-08

Filing date

1999-05-07

Publication date

1999-06-07

1999-05-07 Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co

1999-05-07 Publication of NO992228D0 publication Critical patent/NO992228D0/no

1999-06-07 Publication of NO992228L publication Critical patent/NO992228L/no

Links

-1 3-Aminoindazol-5-yl Chemical group 0.000 title 1
229940122440 HIV protease inhibitor Drugs 0.000 title 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
239000004202 carbamide Substances 0.000 title 1
239000004030 hiv protease inhibitor Substances 0.000 title 1
238000009007 Diagnostic Kit Methods 0.000 abstract 1
108010010369 HIV Protease Proteins 0.000 abstract 1
208000036142 Viral infection Diseases 0.000 abstract 1
238000004458 analytical method Methods 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
150000003839 salts Chemical group 0.000 abstract 1
230000009385 viral infection Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
AIDS & HIV (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO992228A 1996-11-08 1999-05-07 1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor NO992228L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US74710496A	1996-11-08	1996-11-08
US2974596P	1996-11-08	1996-11-08
PCT/US1997/020035 WO1998020008A1 (fr)	1996-11-08	1997-11-04	Urees 1-(3-aminoindazol-5-yl)-3-phenylmethyl-cycliques utiles en tant qu'inhibiteurs de protease de vih

Publications (2)

Publication Number	Publication Date
NO992228D0 NO992228D0 (no)	1999-05-07
NO992228L true NO992228L (no)	1999-06-07

Family

ID=26705293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO992228A NO992228L (no)	1996-11-08	1999-05-07	1-(3-aminoindazol-5-yl)-3-fenylmetyl-syklisk urea egnet som HIV protease inhibitor

Country Status (21)

Country	Link
EP (1)	EP0937067B1 (fr)
JP (1)	JP2001503428A (fr)
KR (1)	KR20000053122A (fr)
CN (1)	CN1235602A (fr)
AT (1)	ATE244714T1 (fr)
AU (1)	AU5165198A (fr)
BR (1)	BR9712910A (fr)
CA (1)	CA2270966A1 (fr)
CZ (1)	CZ157599A3 (fr)
DE (1)	DE69723456T2 (fr)
EA (1)	EA199900452A1 (fr)
EE (1)	EE9900188A (fr)
ES (1)	ES2202645T3 (fr)
HU (1)	HUP9904676A2 (fr)
IL (1)	IL129727A0 (fr)
LV (1)	LV12375B (fr)
NO (1)	NO992228L (fr)
PL (1)	PL333421A1 (fr)
SI (1)	SI20074A (fr)
SK (1)	SK59699A3 (fr)
WO (1)	WO1998020008A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6870098A (en) *	1997-03-31	1998-10-22	Du Pont Merck Pharmaceutical Company, The	Indazoles of cyclic ureas useful as hiv protease inhibitors
US7135575B2 (en)	2003-03-03	2006-11-14	Array Biopharma, Inc.	P38 inhibitors and methods of use thereof
RS52298B (sr)	2006-01-31	2012-12-31	Array Biopharma Inc.	Inhibitori kinaze i postupak njihove upotrebe

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5610294A (en) *	1991-10-11	1997-03-11	The Du Pont Merck Pharmaceutical Company	Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
US5532357A (en) *	1995-06-07	1996-07-02	The Dupont Merck Pharmaceutical Company	Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas

1997
- 1997-11-04 EA EA199900452A patent/EA199900452A1/ru unknown
- 1997-11-04 SI SI9720072A patent/SI20074A/sl unknown
- 1997-11-04 CZ CZ991575A patent/CZ157599A3/cs unknown
- 1997-11-04 CA CA002270966A patent/CA2270966A1/fr not_active Abandoned
- 1997-11-04 HU HU9904676A patent/HUP9904676A2/hu unknown
- 1997-11-04 DE DE69723456T patent/DE69723456T2/de not_active Expired - Fee Related
- 1997-11-04 SK SK596-99A patent/SK59699A3/sk unknown
- 1997-11-04 WO PCT/US1997/020035 patent/WO1998020008A1/fr not_active Ceased
- 1997-11-04 IL IL12972797A patent/IL129727A0/xx unknown
- 1997-11-04 EE EEP199900188A patent/EE9900188A/xx unknown
- 1997-11-04 ES ES97946494T patent/ES2202645T3/es not_active Expired - Lifetime
- 1997-11-04 BR BR9712910A patent/BR9712910A/pt not_active Application Discontinuation
- 1997-11-04 CN CN97199419A patent/CN1235602A/zh active Pending
- 1997-11-04 PL PL97333421A patent/PL333421A1/xx unknown
- 1997-11-04 JP JP52168198A patent/JP2001503428A/ja active Pending
- 1997-11-04 KR KR1019990704048A patent/KR20000053122A/ko not_active Withdrawn
- 1997-11-04 AT AT97946494T patent/ATE244714T1/de not_active IP Right Cessation
- 1997-11-04 AU AU51651/98A patent/AU5165198A/en not_active Abandoned
- 1997-11-04 EP EP97946494A patent/EP0937067B1/fr not_active Expired - Lifetime
1999
- 1999-04-29 LV LVP-99-76A patent/LV12375B/en unknown
- 1999-05-07 NO NO992228A patent/NO992228L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2270966A1 (fr)	1998-05-14
DE69723456T2 (de)	2004-05-27
HUP9904676A2 (hu)	2000-06-28
EE9900188A (et)	1999-12-15
SK59699A3 (en)	1999-12-10
CN1235602A (zh)	1999-11-17
EA199900452A1 (ru)	2000-02-28
BR9712910A (pt)	2000-03-21
JP2001503428A (ja)	2001-03-13
EP0937067A1 (fr)	1999-08-25
IL129727A0 (en)	2000-02-29
SI20074A (sl)	2000-04-30
LV12375B (en)	2000-04-20
NO992228D0 (no)	1999-05-07
ATE244714T1 (de)	2003-07-15
KR20000053122A (ko)	2000-08-25
ES2202645T3 (es)	2004-04-01
PL333421A1 (en)	1999-12-06
WO1998020008A1 (fr)	1998-05-14
AU5165198A (en)	1998-05-29
EP0937067B1 (fr)	2003-07-09
LV12375A (lv)	1999-11-20
DE69723456D1 (de)	2003-08-14
CZ157599A3 (cs)	1999-11-17

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Legal Events

Date	Code	Title	Description
2002-09-02	FC2A	Withdrawal, rejection or dismissal of laid open patent application