NO993709L - Stabilisert blanding omfattende fibrinogen - Google Patents

Stabilisert blanding omfattende fibrinogen

Info

Publication number: NO993709L
Authority: NO; Norway
Prior art keywords: fibrinogen; solution; arginine; lysine; stabilized composition
Prior art date: 1997-01-31

Application number

NO993709A

Other languages

English (en)

Norwegian (no)

Other versions

NO993709D0 (no

Inventor

Israel Nur

Lilliana Bar

Oded Lieberman

Original Assignee

Omrix Biopharm Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-31

Filing date

1999-07-30

Publication date

1999-09-28

1997-01-31 Priority claimed from EP97101569A external-priority patent/EP0856317A1/de

1999-07-30 Application filed by Omrix Biopharm Sa filed Critical Omrix Biopharm Sa

1999-07-30 Publication of NO993709D0 publication Critical patent/NO993709D0/no

1999-09-28 Publication of NO993709L publication Critical patent/NO993709L/no

Links

102000008946 Fibrinogen Human genes 0.000 title abstract 3
108010049003 Fibrinogen Proteins 0.000 title abstract 3
229940012952 fibrinogen Drugs 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
239000000243 solution Substances 0.000 abstract 3
239000004475 Arginine Substances 0.000 abstract 2
239000004472 Lysine Substances 0.000 abstract 2
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 2
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 2
239000012736 aqueous medium Substances 0.000 abstract 1
239000008366 buffered solution Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
210000002381 plasma Anatomy 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 abstract 1
229960000401 tranexamic acid Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Public Health (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

NO993709A 1997-01-31 1999-07-30 Stabilisert blanding omfattende fibrinogen NO993709L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97101569A EP0856317A1 (de)	1997-01-31	1997-01-31	Fibrinogen enthaltende stabilisierte Mischung
PCT/EP1998/000502 WO1998033533A1 (en)	1997-01-31	1998-01-30	A stabilized mixture comprising fibrinogen

Publications (2)

Publication Number	Publication Date
NO993709D0 NO993709D0 (no)	1999-07-30
NO993709L true NO993709L (no)	1999-09-28

Family

ID=8226433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO993709A NO993709L (no)	1997-01-31	1999-07-30	Stabilisert blanding omfattende fibrinogen

Country Status (13)

Country	Link
US (1)	US6121232A (de)
JP (1)	JP3825055B2 (de)
KR (1)	KR100345570B1 (de)
CN (1)	CN1182879C (de)
AT (1)	ATE218365T1 (de)
AU (1)	AU724715B2 (de)
BR (1)	BR9807043A (de)
CA (1)	CA2279419A1 (de)
DE (1)	DE69805772T2 (de)
ES (1)	ES2178153T3 (de)
HU (1)	HUP0000908A3 (de)
NO (1)	NO993709L (de)
PL (1)	PL194316B1 (de)

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US7276235B2 (en) *	1998-11-18	2007-10-02	Zlb Behring Gmbh	Tissue glue with improved antiadhesive properties
DE10025001A1 (de) *	2000-05-22	2001-11-29	Aventis Behring Gmbh	Gewebekleber mit verbesserten anti-adhäsiven Eigenschaften
CN100345591C (zh) *	2003-08-01	2007-10-31	上海新兴医药股份有限公司	耐干热处理的速溶冻干纤维蛋白原制剂
US7186684B2 (en) *	2003-08-07	2007-03-06	Ethicon, Inc.	Hemostatic device containing a protein precipitate
EP1809343B1 (de) *	2004-10-20	2012-08-15	Ethicon, Inc.	Verstärkter resorbierbarer mehrschichtiger hämostatischer wundverband und herstellungsverfahren
US9358318B2 (en) *	2004-10-20	2016-06-07	Ethicon, Inc.	Method of making a reinforced absorbable multilayered hemostatic wound dressing
FR2887883B1 (fr)	2005-06-29	2007-08-31	Lab Francais Du Fractionnement	Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
WO2008117746A1 (ja) *	2007-03-22	2008-10-02	Juridical Foundation The Chemo-Sero-Therapeutic Research Institute	固体状フィブリノゲン製剤
EP2011524A1 (de) *	2007-07-02	2009-01-07	Omrix Biopharmaceuticals Ltd.	Fibrinleim mit Visualisierungsmittel
EP2034010A1 (de)	2007-08-30	2009-03-11	Omrix Biopharmaceuticals Ltd.	Zusammensetzungen zur Reparatur und/oder Behandlung von verletztem Rückenmarksgewebe
EP2331158B1 (de) *	2008-09-22	2013-09-11	Omrix Biopharmaceuticals Ltd.	Implantierbare vorrichtung mit einem substrat, das mit stabilisiertem fibrin vorbeschichtet ist
EP2398394B1 (de)	2009-02-20	2021-08-04	Omrix Biopharmaceuticals Ltd.	Vorrichtung zur verabreichung einer aus mindestens zwei komponenten bestehenden substanz
MX2012008845A (es) *	2010-01-28	2012-09-28	Omrix Biopharmaceuticals Ltd	Metodo para sellado de fibrina mejorado.
IL207586A0 (en)	2010-08-12	2010-12-30	Omrix Biopharmaceuticals Ltd	A fibrin based therapeutic preparation and use thereof
AU2011303467C1 (en) *	2010-09-15	2017-03-09	Debiopharm International Sa	Method for separating target molecules or particles from fibrinogen-containing samples including blood components
EP2624823A4 (de)	2010-09-23	2016-08-03	Inflammagen	Verabreichung von serinproteasehemmern in den magen
IL210162A0 (en)	2010-12-21	2011-03-31	Omrix Biopharmaceuticals	Viral inactivated platelet extract, use and preparation thereof
IL213375A0 (en)	2011-06-05	2011-07-31	Omrix Biopharmaceuticals	Device for spraying fluids in proximity to a surface
US20150064141A1 (en)	2012-04-05	2015-03-05	The Regents Of The University Of California	Regenerative sera cells and mesenchymal stem cells
US10130346B2 (en)	2012-07-24	2018-11-20	Omrix Biopharmaceuticals Ltd.	Device and method for the application of a curable fluid composition to a bodily organ
JP6254187B2 (ja)	2012-12-20	2017-12-27	オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘＢｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ．	ウイルス不活性化生物学的混合物
BR112015015703A2 (pt)	2012-12-30	2020-02-04	Omrix Biopharmaceuticals Ltd	dispositivo e método para a aplicação de uma composição fluida curável a uma porção de um órgão do corpo
USD754325S1 (en)	2013-06-06	2016-04-19	Omrix Biopharmaceuticals Ltd.	Device of a curable fluid composition to a bodily organ
IL230151A0 (en)	2013-12-24	2014-09-30	Omrix Biopharmaceuticals Ltd	One-component fibrin glue containing a polymerization inhibitor
IL230150A0 (en)	2013-12-24	2014-09-30	Omrix Biopharmaceuticals Ltd	One-component fibrin glue containing zymogens
KR20220068266A (ko)	2014-03-25	2022-05-25	리딩 바이오사이언시즈, 인크.	자가소화의 치료용의 조성물
IL231792A0 (en)	2014-03-27	2014-08-31	Omrix Biopharmaceuticals Ltd	Device and method for the preparation and administration of one-component fibrin glue
IL234246A0 (en)	2014-08-21	2014-11-30	Omrix Biopharmaceuticals Ltd	Stabilized thrombin
IL235751A0 (en)	2014-11-18	2015-02-26	Omrix Biopharmaceuticals Ltd	An addition to the spray dryer
BR112017010250A2 (pt)	2014-11-18	2018-01-02	Omrix Biopharmaceuticals Ltd	aparelho para secagem por aspersão e método de uso do mesmo
US10066224B2 (en)	2015-02-25	2018-09-04	Omrix Biopharmaceuticals Ltd.	Method for purifying and quantifying thrombin and its degradation polypeptides
IL242984A0 (en)	2015-12-08	2016-02-29	Omrix Biopharmaceuticals Ltd	Thrombin microcapsules, their preparation and how to use them
US10159720B2 (en)	2015-12-08	2018-12-25	Omrix Biopharmaceuticals Ltd	Thrombin microcapsules, preparation and uses thereof
IL242924A0 (en)	2015-12-03	2016-04-21	Omrix Biopharmaceuticals Ltd	Syringe system for storing and mixing two ingredients
CA3010986A1 (en)	2016-01-11	2017-07-20	Leading BioSciences, Inc.	Compositions and methods for treating and preventing adhesions and ileus
JP2017176713A (ja) *	2016-03-31	2017-10-05	テルモ株式会社	塗布具
IL247821A0 (en) *	2016-09-14	2017-01-31	Omrix Biopharmaceuticals Ltd	Adhesive preparations and their use
CN109081789B (zh) *	2017-06-13	2021-01-01	首都医科大学	氨基正己酰氨基甲环酰氨基正己酰脂肪氨基酸，其合成，活性和应用
IL261190A (en)	2018-08-16	2019-01-31	Omrix Biopharmaceuticals Ltd	Stable liquid preparations of thrombin
IL263679A (en) *	2018-12-12	2019-03-31	Omrix Biopharmaceuticals Ltd	Kits, methods, and compositions for preventing tissue adhesion
WO2020121290A1 (en)	2018-12-12	2020-06-18	Omrix Biopharmaceuticals Ltd.	High concentrated protein compositions for preventing tissue adhesion
JP2024534444A (ja)	2021-09-16	2024-09-20	エシコン・インコーポレイテッド	組織経路封止用組成物のためのキット
WO2023119277A1 (en)	2021-12-21	2023-06-29	Omrix Biopharmaceuticals Ltd.	Highly soluble fibrinogen compositions
US20250108142A1 (en)	2023-09-28	2025-04-03	Ethicon, Inc.	Methods for treating leakage from a gastrointestinal site

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AT359653B (de) *	1979-02-15	1980-11-25	Immuno Ag	Verfahren zur herstellung eines gewebekleb- stoffes
DK475386D0 (da) *	1986-10-03	1986-10-03	Weis Fogh Ulla Sivertsen	Fremgangsmaade og apparat til fremstilling af biologiske stoffer
US5278189A (en) *	1990-06-04	1994-01-11	Rath Matthias W	Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A)
ATE187651T1 (de) *	1993-03-30	2000-01-15	Omrix Biopharm Sa	Zweikomponenten-fibrinkleber

1997
- 1997-02-10 US US08/797,328 patent/US6121232A/en not_active Expired - Lifetime
1998
- 1998-01-30 CN CNB988021757A patent/CN1182879C/zh not_active Expired - Fee Related
- 1998-01-30 KR KR1019997006883A patent/KR100345570B1/ko not_active Expired - Fee Related
- 1998-01-30 HU HU0000908A patent/HUP0000908A3/hu unknown
- 1998-01-30 CA CA002279419A patent/CA2279419A1/en not_active Abandoned
- 1998-01-30 PL PL98334547A patent/PL194316B1/pl unknown
- 1998-01-30 ES ES98904163T patent/ES2178153T3/es not_active Expired - Lifetime
- 1998-01-30 AT AT98904163T patent/ATE218365T1/de active
- 1998-01-30 AU AU62145/98A patent/AU724715B2/en not_active Ceased
- 1998-01-30 JP JP53253698A patent/JP3825055B2/ja not_active Expired - Fee Related
- 1998-01-30 BR BR9807043-6A patent/BR9807043A/pt not_active IP Right Cessation
- 1998-01-30 DE DE69805772T patent/DE69805772T2/de not_active Expired - Lifetime
1999
- 1999-07-30 NO NO993709A patent/NO993709L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO993709D0 (no)	1999-07-30
JP2000509630A (ja)	2000-08-02
AU724715B2 (en)	2000-09-28
JP3825055B2 (ja)	2006-09-20
AU6214598A (en)	1998-08-25
ES2178153T3 (es)	2002-12-16
KR20000070634A (ko)	2000-11-25
CN1182879C (zh)	2005-01-05
PL194316B1 (pl)	2007-05-31
CA2279419A1 (en)	1998-08-06
DE69805772D1 (de)	2002-07-11
HUP0000908A3 (en)	2001-05-28
HUP0000908A2 (hu)	2000-08-28
US6121232A (en)	2000-09-19
CN1246069A (zh)	2000-03-01
BR9807043A (pt)	2000-03-28
ATE218365T1 (de)	2002-06-15
KR100345570B1 (ko)	2002-07-26
PL334547A1 (en)	2000-03-13
DE69805772T2 (de)	2003-01-30

Legal Events

Date	Code	Title	Description
2002-09-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO993709L (no)	1999-09-28	Stabilisert blanding omfattende fibrinogen
JPS6440433A (en)	1989-02-10	Aqueous liquid composition of thrombin
DK0830376T3 (da)	2004-05-24	Fremgangsmåde til fremstilling af erythropoietin, som er fri for animalske proteiner
KR920019371A (ko)	1992-11-19	안정화된 인자 ⅷ 제제
BR9610511B1 (pt)	2010-10-19	construções de dna, úteis em terapia genética, compreendendo ao menos uma sequência nucléica de interesse e composição farmacêutica.
CA2034489A1 (en)	1990-12-16	Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions
IL143670A0 (en)	2002-04-21	Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same
ATE205090T1 (de)	2001-09-15	Eine glucagon enthaltende pharmazeutische zubereitung
ATA29997A (de)	1999-05-15	Verfahren zur inaktivierung von lipidumhüllten viren
BG60102B2 (bg)	1993-10-29	Метод за получаване на 5-флуор-2(((4-циклопропил- метокси-2-пиридинил)метил)тионил)-1н-бензимидазол
ES2053676T3 (es)	1994-08-01	Formulacion de proteinas plasmaticas y recombinantes en medios de fuerza ionica elevada.
DK0454898T3 (da)	1996-04-15	Glycosaminoglycan-modificeret protein, fremgangsmåde til fremstilling af proteinet, farmaceutiske præparater indeholdende proteinet samt anvendelse af proteinet
ATE79273T1 (de)	1992-08-15	Stabilisierte zusammensetzungen von menschlichen aktivatoren des gewebeplasminogens.
JPS6485096A (en)	1989-03-30	Hybrid human protein c and biotechnological synthesis thereof
ATE223728T1 (de)	2002-09-15	Stabilisierte pharmazeutische zusammensetzung von bdnf
DE69728869D1 (de)	2004-06-03	Von aminosauren und hydroxysauren substituierte benzamidinderivate und deren verwendung als antikoagulantien
ATE211391T1 (de)	2002-01-15	Verwendung von hmg proteinen zur herstellung von arzneimitteln mit zytotoxischer wirkung
BR9808376A (pt)	2000-05-23	Moléculas bi- ou multifuncionais com base em uma armação de dendroaspina
DK0754463T3 (da)	2004-06-28	Stabiliserede vandige flydende præparater af blodkoagulationsfaktor XIII
ATE272436T1 (de)	2004-08-15	Mikrofiltration unter verwendung von aktivkohle
ATE373083T1 (de)	2007-09-15	Methode und zusammensetzungen zur identifizierung von morphogen-analogen
DK165411C (da)	1993-04-13	Fremgangsmaade til oploesning af peptider, anvendelse deraf og ikke-vandige oploesninger indeholdende peptid/crown-ether complexer
ES2170747T3 (es)	2002-08-16	Analogos superiores de trombomodulina para uso farmaceutico.
DE19781038T1 (de)	1998-12-10	Keratinozytenwachstumsfaktor-2-Produkte
AR004224A1 (es)	1998-11-04	Procedimiento para la inactivacion de virus en soluciones de proteinas