NO993709L - Stabilisert blanding omfattende fibrinogen - Google Patents

Stabilisert blanding omfattende fibrinogen

Info

Publication number: NO993709L
Authority: NO; Norway
Prior art keywords: fibrinogen; solution; arginine; lysine; stabilized composition
Prior art date: 1997-01-31

Application number

NO993709A

Other languages

English (en)

Norwegian (no)

Other versions

NO993709D0 (no

Inventor

Israel Nur

Lilliana Bar

Oded Lieberman

Original Assignee

Omrix Biopharm Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-31

Filing date

1999-07-30

Publication date

1999-09-28

1997-01-31 Priority claimed from EP97101569A external-priority patent/EP0856317A1/en

1999-07-30 Application filed by Omrix Biopharm Sa filed Critical Omrix Biopharm Sa

1999-07-30 Publication of NO993709D0 publication Critical patent/NO993709D0/no

1999-09-28 Publication of NO993709L publication Critical patent/NO993709L/no

Links

102000008946 Fibrinogen Human genes 0.000 title abstract 3
108010049003 Fibrinogen Proteins 0.000 title abstract 3
229940012952 fibrinogen Drugs 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
239000000243 solution Substances 0.000 abstract 3
239000004475 Arginine Substances 0.000 abstract 2
239000004472 Lysine Substances 0.000 abstract 2
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 2
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 2
239000012736 aqueous medium Substances 0.000 abstract 1
239000008366 buffered solution Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
210000002381 plasma Anatomy 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 abstract 1
229960000401 tranexamic acid Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Surgery (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)

NO993709A 1997-01-31 1999-07-30 Stabilisert blanding omfattende fibrinogen NO993709L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97101569A EP0856317A1 (en)	1997-01-31	1997-01-31	A stabilized mixture comprising fibrinogen
PCT/EP1998/000502 WO1998033533A1 (en)	1997-01-31	1998-01-30	A stabilized mixture comprising fibrinogen

Publications (2)

Publication Number	Publication Date
NO993709D0 NO993709D0 (no)	1999-07-30
NO993709L true NO993709L (no)	1999-09-28

Family

ID=8226433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO993709A NO993709L (no)	1997-01-31	1999-07-30	Stabilisert blanding omfattende fibrinogen

Country Status (13)

Country	Link
US (1)	US6121232A (ko)
JP (1)	JP3825055B2 (ko)
KR (1)	KR100345570B1 (ko)
CN (1)	CN1182879C (ko)
AT (1)	ATE218365T1 (ko)
AU (1)	AU724715B2 (ko)
BR (1)	BR9807043A (ko)
CA (1)	CA2279419A1 (ko)
DE (1)	DE69805772T2 (ko)
ES (1)	ES2178153T3 (ko)
HU (1)	HUP0000908A3 (ko)
NO (1)	NO993709L (ko)
PL (1)	PL194316B1 (ko)

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DE10025001A1 (de) *	2000-05-22	2001-11-29	Aventis Behring Gmbh	Gewebekleber mit verbesserten anti-adhäsiven Eigenschaften
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CN100345591C (zh) *	2003-08-01	2007-10-31	上海新兴医药股份有限公司	耐干热处理的速溶冻干纤维蛋白原制剂
US7186684B2 (en) *	2003-08-07	2007-03-06	Ethicon, Inc.	Hemostatic device containing a protein precipitate
CN102091347A (zh) *	2004-10-20	2011-06-15	伊西康公司	可吸收的止血物
US9358318B2 (en) *	2004-10-20	2016-06-07	Ethicon, Inc.	Method of making a reinforced absorbable multilayered hemostatic wound dressing
FR2887883B1 (fr)	2005-06-29	2007-08-31	Lab Francais Du Fractionnement	Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
ES2485901T3 (es) *	2007-03-22	2014-08-14	The Chemo-Sero-Therapeutic Research Institute	Preparación sólida de fibrinógeno
EP2011524A1 (en)	2007-07-02	2009-01-07	Omrix Biopharmaceuticals Ltd.	Fibrin glue with a visualization agent
EP2034010A1 (en)	2007-08-30	2009-03-11	Omrix Biopharmaceuticals Ltd.	Compositions suitable for repair and/or treatment of injured spinal tissue
US10039865B2 (en) *	2008-09-22	2018-08-07	Omrix Biopharmaceuticals Ltd.	Implantable device comprising a substrate pre-coated with stabilized fibrin
JP5805542B2 (ja) *	2009-02-20	2015-11-04	オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘＢｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ．	少なくとも２成分の薬物を投与する装置
KR101786786B1 (ko) *	2010-01-28	2017-10-18	옴릭스 바이오파머슈티컬스 리미티드	개선된 피브린 밀봉 방법
IL207586A0 (en)	2010-08-12	2010-12-30	Omrix Biopharmaceuticals Ltd	A fibrin based therapeutic preparation and use thereof
CN107389932B (zh) *	2010-09-15	2019-11-22	德比奥法姆国际股份有限公司	用于从含纤维蛋白原的样品中分离目标分子或颗粒的方法
ES2951828T3 (es)	2010-09-23	2023-10-25	Leading Biosciences Inc	Administración de inhibidores de serina proteasa al estómago
IL210162A0 (en)	2010-12-21	2011-03-31	Omrix Biopharmaceuticals	Viral inactivated platelet extract, use and preparation thereof
IL213375A0 (en)	2011-06-05	2011-07-31	Omrix Biopharmaceuticals	Device for spraying fluids in proximity to a surface
US20150064141A1 (en)	2012-04-05	2015-03-05	The Regents Of The University Of California	Regenerative sera cells and mesenchymal stem cells
US10130346B2 (en)	2012-07-24	2018-11-20	Omrix Biopharmaceuticals Ltd.	Device and method for the application of a curable fluid composition to a bodily organ
EP2934603A1 (en)	2012-12-20	2015-10-28	Omrix Biopharmaceuticals Ltd.	Viral inactivated biological mixture
BR112015015703A2 (pt)	2012-12-30	2020-02-04	Omrix Biopharmaceuticals Ltd	dispositivo e método para a aplicação de uma composição fluida curável a uma porção de um órgão do corpo
USD754325S1 (en)	2013-06-06	2016-04-19	Omrix Biopharmaceuticals Ltd.	Device of a curable fluid composition to a bodily organ
IL230150A0 (en)	2013-12-24	2014-09-30	Omrix Biopharmaceuticals Ltd	One-component fibrin glue containing zymogens
IL230151A0 (en)	2013-12-24	2014-09-30	Omrix Biopharmaceuticals Ltd	One-component fibrin glue containing a polymerization inhibitor
EP3122349B1 (en)	2014-03-25	2021-12-22	Leading Biosciences, Inc.	Compositions for the treatment of autodigestion
IL231792A0 (en)	2014-03-27	2014-08-31	Omrix Biopharmaceuticals Ltd	Device and method for the preparation and administration of one-component fibrin glue
IL234246A0 (en)	2014-08-21	2014-11-30	Omrix Biopharmaceuticals Ltd	Stabilized thrombin
IL235751A0 (en)	2014-11-18	2015-02-26	Omrix Biopharmaceuticals Ltd	An addition to the spray dryer
WO2016079727A1 (en)	2014-11-18	2016-05-26	Omrix Biopharmaceuticals Ltd.	Spray-drying apparatus and method of use
CA2976875A1 (en)	2015-02-25	2016-09-01	Omrix Biopharmaceuticals Ltd.	Method for purifying and quantifying thrombin and its degradation polypeptides
US10159720B2 (en)	2015-12-08	2018-12-25	Omrix Biopharmaceuticals Ltd	Thrombin microcapsules, preparation and uses thereof
IL242984A0 (en)	2015-12-08	2016-02-29	Omrix Biopharmaceuticals Ltd	Thrombin microcapsules, their preparation and how to use them
IL242924A0 (en)	2015-12-03	2016-04-21	Omrix Biopharmaceuticals Ltd	Syringe system for storing and mixing two ingredients
CN108883086B (zh)	2016-01-11	2021-10-26	恒翼生物医药科技(上海)有限公司	用于治疗和预防粘连及肠梗阻的组合物和方法
JP2017177073A (ja) *	2016-03-31	2017-10-05	テルモ株式会社	塗布具
IL247821A0 (en)	2016-09-14	2017-01-31	Omrix Biopharmaceuticals Ltd	Adhesive preparations and their use
CN109081789B (zh) *	2017-06-13	2021-01-01	首都医科大学	氨基正己酰氨基甲环酰氨基正己酰脂肪氨基酸，其合成，活性和应用
IL261190A (en)	2018-08-16	2019-01-31	Omrix Biopharmaceuticals Ltd	Stable liquid preparations of thrombin
IL263679A (en)	2018-12-12	2019-03-31	Omrix Biopharmaceuticals Ltd	Kits, methods, and compositions for preventing tissue adhesion
WO2020121290A1 (en)	2018-12-12	2020-06-18	Omrix Biopharmaceuticals Ltd.	High concentrated protein compositions for preventing tissue adhesion
JP2024534444A (ja)	2021-09-16	2024-09-20	エシコン・インコーポレイテッド	組織経路封止用組成物のためのキット
US20250073313A1 (en)	2021-12-21	2025-03-06	Omrix Biopharmaceuticals Ltd.	Highly soluble fibrinogen compositions
US20250108142A1 (en)	2023-09-28	2025-04-03	Ethicon, Inc.	Methods for treating leakage from a gastrointestinal site

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AT359653B (de) *	1979-02-15	1980-11-25	Immuno Ag	Verfahren zur herstellung eines gewebekleb- stoffes
DK475386D0 (da) *	1986-10-03	1986-10-03	Weis Fogh Ulla Sivertsen	Fremgangsmaade og apparat til fremstilling af biologiske stoffer
US5278189A (en) *	1990-06-04	1994-01-11	Rath Matthias W	Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A)
DE69422165T2 (de) *	1993-03-30	2001-10-04	Omrix Biopharmaceuticals S.A., Bruessel/Bruxelles	Zweikomponenten-fibrinkleber

1997
- 1997-02-10 US US08/797,328 patent/US6121232A/en not_active Expired - Lifetime
1998
- 1998-01-30 PL PL98334547A patent/PL194316B1/pl unknown
- 1998-01-30 KR KR1019997006883A patent/KR100345570B1/ko not_active Expired - Fee Related
- 1998-01-30 DE DE69805772T patent/DE69805772T2/de not_active Expired - Lifetime
- 1998-01-30 HU HU0000908A patent/HUP0000908A3/hu unknown
- 1998-01-30 AU AU62145/98A patent/AU724715B2/en not_active Ceased
- 1998-01-30 JP JP53253698A patent/JP3825055B2/ja not_active Expired - Fee Related
- 1998-01-30 ES ES98904163T patent/ES2178153T3/es not_active Expired - Lifetime
- 1998-01-30 BR BR9807043-6A patent/BR9807043A/pt not_active IP Right Cessation
- 1998-01-30 CN CNB988021757A patent/CN1182879C/zh not_active Expired - Fee Related
- 1998-01-30 AT AT98904163T patent/ATE218365T1/de active
- 1998-01-30 CA CA002279419A patent/CA2279419A1/en not_active Abandoned
1999
- 1999-07-30 NO NO993709A patent/NO993709L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU724715B2 (en)	2000-09-28
ATE218365T1 (de)	2002-06-15
AU6214598A (en)	1998-08-25
PL194316B1 (pl)	2007-05-31
PL334547A1 (en)	2000-03-13
KR100345570B1 (ko)	2002-07-26
ES2178153T3 (es)	2002-12-16
JP3825055B2 (ja)	2006-09-20
HUP0000908A2 (hu)	2000-08-28
US6121232A (en)	2000-09-19
DE69805772D1 (de)	2002-07-11
CA2279419A1 (en)	1998-08-06
KR20000070634A (ko)	2000-11-25
NO993709D0 (no)	1999-07-30
HUP0000908A3 (en)	2001-05-28
BR9807043A (pt)	2000-03-28
JP2000509630A (ja)	2000-08-02
DE69805772T2 (de)	2003-01-30
CN1246069A (zh)	2000-03-01
CN1182879C (zh)	2005-01-05

Legal Events

Date	Code	Title	Description
2002-09-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO993709D0 (no)	1999-07-30	Stabilisert blanding omfattende fibrinogen
DK1394179T3 (da)	2006-11-20	Fremgangsmåde til fremstilling af erythropoietin fri for animalske proteiner
KR920019371A (ko)	1992-11-19	안정화된 인자 ⅷ 제제
BR9610511B1 (pt)	2010-10-19	construções de dna, úteis em terapia genética, compreendendo ao menos uma sequência nucléica de interesse e composição farmacêutica.
ATE248150T1 (de)	2003-09-15	Lactam-enthaltende hydroxamsäure-derivate, deren herstellung und deren verwendung als inhibitoren von matrix-metalloproteasen
CA2034489A1 (en)	1990-12-16	Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions
IL143670A0 (en)	2002-04-21	Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same
DE69522562D1 (de)	2001-10-11	Eine glucagon enthaltende pharmazeutische zubereitung
ATA29997A (de)	1999-05-15	Verfahren zur inaktivierung von lipidumhüllten viren
DK0454898T3 (da)	1996-04-15	Glycosaminoglycan-modificeret protein, fremgangsmåde til fremstilling af proteinet, farmaceutiske præparater indeholdende proteinet samt anvendelse af proteinet
JPS6485096A (en)	1989-03-30	Hybrid human protein c and biotechnological synthesis thereof
ATE265409T1 (de)	2004-05-15	Von aminosauren und hydroxysauren substituierte benzamidinderivate und deren verwendung als antikoagulantien
DE69715414D1 (de)	2002-10-17	Stabilisierte pharmazeutische zusammensetzung von bdnf
DE69023648D1 (de)	1995-12-21	Herstellung eines virus und reinigung von virenüberzugsproteinen zur impfstoffverwendung.
TW337997B (en)	1998-08-11	Pharmaceutical preparation containing plasminogen activators
ATE272436T1 (de)	2004-08-15	Mikrofiltration unter verwendung von aktivkohle
ATE262315T1 (de)	2004-04-15	Stabilisiertes wässriges flüssiges blutgerinnungsfaktor xiii-präparat
ATE373083T1 (de)	2007-09-15	Methode und zusammensetzungen zur identifizierung von morphogen-analogen
DK165411C (da)	1993-04-13	Fremgangsmaade til oploesning af peptider, anvendelse deraf og ikke-vandige oploesninger indeholdende peptid/crown-ether complexer
ES2170747T3 (es)	2002-08-16	Analogos superiores de trombomodulina para uso farmaceutico.
DK0935652T3 (da)	2004-07-26	Keratinocyt vækstfaktor-2 produkter
AR004224A1 (es)	1998-11-04	Procedimiento para la inactivacion de virus en soluciones de proteinas
ATE149354T1 (de)	1997-03-15	Pharmazeutische zusammensetzung von stabilisiertem (leu 13>-motilin-hse
FI102541B1 (fi)	1998-12-31	Uudet glukoosi-isomeraasientsyymit ja niiden käyttö
NO963806L (no)	1996-09-11	Rekombinante viruser som koder for en glutamat-dekarboksylase (GAD)aktivitet