OA08720A - Activated RNase L as a maker for viral infections. - Google Patents

Activated RNase L as a maker for viral infections.

Info

Publication number
OA08720A
OA08720A OA59294A OA59294A OA08720A OA 08720 A OA08720 A OA 08720A OA 59294 A OA59294 A OA 59294A OA 59294 A OA59294 A OA 59294A OA 08720 A OA08720 A OA 08720A
Authority
OA
OAPI
Prior art keywords
pathway
rnase
aids
biochemical
inhibitor
Prior art date
Application number
OA59294A
Other languages
English (en)
Inventor
William A Carter
Original Assignee
Hem Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Res Inc filed Critical Hem Res Inc
Publication of OA08720A publication Critical patent/OA08720A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/922—Ribonucleases (RNAses); Deoxyribonucleases (DNAses)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
OA59294A 1987-03-03 1988-03-03 Activated RNase L as a maker for viral infections. OA08720A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2137287A 1987-03-03 1987-03-03

Publications (1)

Publication Number Publication Date
OA08720A true OA08720A (en) 1989-03-31

Family

ID=21803819

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59294A OA08720A (en) 1987-03-03 1988-03-03 Activated RNase L as a maker for viral infections.

Country Status (20)

Country Link
EP (1) EP0285263B1 (de)
JP (1) JPH0675520B2 (de)
KR (1) KR880011593A (de)
AT (1) ATE107964T1 (de)
AU (1) AU618525B2 (de)
CA (1) CA1337278C (de)
DE (1) DE3850428T2 (de)
DK (1) DK112888A (de)
ES (1) ES2058252T3 (de)
FI (1) FI880959A7 (de)
IE (1) IE66831B1 (de)
IL (1) IL85576A0 (de)
MX (1) MX173802B (de)
NO (1) NO880934L (de)
NZ (1) NZ223721A (de)
OA (1) OA08720A (de)
PH (1) PH30882A (de)
PT (1) PT86878B (de)
RU (1) RU2049336C1 (de)
ZA (1) ZA881471B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0306347B1 (de) * 1987-09-04 1995-05-10 Hem Pharmaceuticals Corp. Diagnose von Mangelzuständen doppelsträngiger RNS
US5593973A (en) * 1987-09-04 1997-01-14 Hemispherx Biopharma Inc. Treatment of viral hepatitis with mismatched dsRNA
AU724056B2 (en) * 1987-09-04 2000-09-14 Hem Research, Inc. Diagnosis and treatment of double stranded deficiency states
DE68914201T2 (de) * 1988-07-07 1994-07-14 Hem Pharma Corp Diagnose und Behandlung chronischer Ermüdungserscheinungen.
US5985565A (en) * 1996-10-09 1999-11-16 Temple University-Of The Commonwealth System Of Higher Education Chronic fatigue syndrome diagnosis
US6207366B1 (en) 1999-04-14 2001-03-27 Temple University- Of The Commonwealth System Of Higher Education Chronic fatigue syndrome diagnosis
US6080554A (en) * 1999-04-27 2000-06-27 R.E.D. Laboratories, N.V. Methods and compositions for use in characterizing multiple sclerosis disease activity in a subject
RU2202110C1 (ru) * 2001-07-26 2003-04-10 Научно-исследовательский испытательный центр (медико-биологической защиты) Государственного научно-исследовательского испытательного института военной медицины МО РФ Способ определения активности и функционального состояния синтетазы оксида азота
WO2017193051A1 (en) * 2016-05-06 2017-11-09 The Trustees Of Princeton University Methods of monitoring rnase l activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0113162B1 (de) * 1982-09-16 1989-07-19 Hem Research, Inc. Wucherungshemmende Wirkung von ds-Ribonucleinsäuren auf Tumorzellen
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
PT86878B (pt) 1992-05-29
IE880587L (en) 1988-09-03
FI880959A0 (fi) 1988-03-02
ZA881471B (en) 1988-12-28
DE3850428T2 (de) 1994-11-24
IL85576A0 (en) 1988-08-31
AU1256388A (en) 1988-09-01
FI880959A7 (fi) 1988-09-04
KR880011593A (ko) 1988-10-29
MX173802B (es) 1994-03-29
DE3850428D1 (de) 1994-08-04
JPH0675520B2 (ja) 1994-09-28
RU2049336C1 (ru) 1995-11-27
JPS63309200A (ja) 1988-12-16
PT86878A (pt) 1988-04-01
NO880934L (no) 1988-09-05
NO880934D0 (no) 1988-03-02
AU618525B2 (en) 1992-01-02
EP0285263B1 (de) 1994-06-29
CA1337278C (en) 1995-10-10
ES2058252T3 (es) 1994-11-01
DK112888D0 (da) 1988-03-02
IE66831B1 (en) 1996-02-07
PH30882A (en) 1997-12-23
DK112888A (da) 1988-09-04
EP0285263A2 (de) 1988-10-05
ATE107964T1 (de) 1994-07-15
EP0285263A3 (en) 1990-04-18
NZ223721A (en) 1991-02-26

Similar Documents

Publication Publication Date Title
Player et al. The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
PH30882A (en) Activated Rnase L as a maker for viral infections.
WO1994023041A3 (en) Method for selective inactivation of viral replication
NZ228645A (en) 1,3-dioxolane derivatives substituted in the 5th position by a purine or pyrimidine radical; treatment of viral infections
FI883763A0 (fi) Frigoering av vaerdens foersvarsmediatorer i biologiska vaetskor genom systematisk behandling med dubbelstraengat rna.
ZA931647B (en) Therapeutic nucleosides
SE8601435D0 (sv) Aktivt pansar
EP0135713A3 (de) Antivirale Zusammensetzungen
PT84219A (en) Process for the preparation of an antiviral compound containin g an antiviral purine nucleoside and a transport inhibiting nucleoside
IE880588L (en) Synergistic interplay of lymphokines and double-stranded¹RNAs
ES8100620A1 (es) Perfeccionamientos en empunaduras de pistola
GB2011041A (en) Practice or Fragmentation Projectiles
DK615788A (da) Nucleosidforbindelser til anvendelse mod virale infektioner
ES2000853A6 (es) Proyectil portador para mortero
DK0625158T3 (da) Terapeutiske nucleosider af 2',3'-dideoxy-3'-fluorpurinrækken
EP0034424A3 (de) Siebengliedrige Ringverbindungen als Cytidin-Deaminase-Inhibitoren
DE60128565D1 (en) Polycyclische xanthone als antibiotika
ES8303680A1 (es) "perfeccionamientos en la fabricacion de proyectiles con accionamiento pirotecnico".
WO1988007080A3 (en) Transgenic animal cells resistant to viral infection
ES2053601T3 (es) Agentes de biocontrol fundidos.
YU53790A (sh) Postupak za inhibiciju hiv korišćenjem sinergističkih kombinacija nukleozidnih derivata
GB1411748A (en) Derivatives of double-stranded rna