OA12053A - HexahydrofuroÄ2,3-bÜfuran-3-yl-N-ä3-Ä(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)aminoÜ-1-benzyl-2-hydroxypropylücarbamate as retroviral protease inhibitor. - Google Patents

HexahydrofuroÄ2,3-bÜfuran-3-yl-N-ä3-Ä(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)aminoÜ-1-benzyl-2-hydroxypropylücarbamate as retroviral protease inhibitor. Download PDF

Info

Publication number: OA12053A
Authority: OA; OAPI
Prior art keywords: compound; daims; substance; composition; retrovirus
Prior art date: 1999-10-06

Application number

OA1200200096A

Other languages

English (en)

Inventor

Piet Tom Bert Paul Wigerinck

Guangyang Wang

Michael Eissenstat

John W Erickson

Original Assignee

Tibotec Pharm Ltd

Us Gov Health & Human Serv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-06

Filing date

2000-10-06

Publication date

2006-05-02

2000-10-06 Application filed by Tibotec Pharm Ltd, Us Gov Health & Human Serv filed Critical Tibotec Pharm Ltd

2006-05-02 Publication of OA12053A publication Critical patent/OA12053A/en

Links

230000001177 retroviral effect Effects 0.000 title claims description 5
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229940124158 Protease/peptidase inhibitor Drugs 0.000 title description 3
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
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Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

OA1200200096A 1999-10-06 2000-10-06 HexahydrofuroÄ2,3-bÜfuran-3-yl-N-ä3-Ä(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)aminoÜ-1-benzyl-2-hydroxypropylücarbamate as retroviral protease inhibitor. OA12053A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US15785099P	1999-10-06	1999-10-06

Publications (1)

Publication Number	Publication Date
OA12053A true OA12053A (en)	2006-05-02

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ID=22565540

Family Applications (1)

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OA1200200096A OA12053A (en)	1999-10-06	2000-10-06	HexahydrofuroÄ2,3-bÜfuran-3-yl-N-ä3-Ä(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)aminoÜ-1-benzyl-2-hydroxypropylücarbamate as retroviral protease inhibitor.

Country Status (25)

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US (2)	US6649651B1 (da)
EP (1)	EP1222192B8 (da)
JP (1)	JP4951179B2 (da)
KR (1)	KR100792391B1 (da)
CN (1)	CN1191256C (da)
AP (1)	AP1459A (da)
AT (1)	ATE398623T1 (da)
AU (1)	AU781656B2 (da)
BR (1)	BR0014602A (da)
CA (1)	CA2386850C (da)
CZ (1)	CZ300031B6 (da)
DE (1)	DE60039244D1 (da)
DK (1)	DK1222192T3 (da)
ES (1)	ES2307533T3 (da)
HU (1)	HU228938B1 (da)
IL (2)	IL149005A0 (da)
MX (1)	MXPA02003607A (da)
NO (1)	NO327996B1 (da)
NZ (1)	NZ518580A (da)
OA (1)	OA12053A (da)
PL (1)	PL204924B1 (da)
RU (1)	RU2247123C2 (da)
SK (1)	SK287153B6 (da)
WO (1)	WO2001025240A1 (da)
ZA (1)	ZA200202655B (da)

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US7981929B2 (en) *	2007-03-16	2011-07-19	Sequoia Pharmaceuticals, Inc.	Benzofuran derived HIV protease inhibitors
CN101796040A (zh)	2007-07-06	2010-08-04	吉里德科学公司	治疗剂的药代动力学特性调节剂
PT2231628E (pt)	2008-01-04	2015-12-29	Gilead Sciences Inc	Inibidores de citocromo p450
WO2009091941A1 (en) *	2008-01-17	2009-07-23	Purdue Research Foundation	Small molecule inhibitors of hiv proteases
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2000
- 2000-10-06 WO PCT/EP2000/009917 patent/WO2001025240A1/en not_active Ceased
- 2000-10-06 CN CNB008165874A patent/CN1191256C/zh not_active Expired - Lifetime
- 2000-10-06 IL IL14900500A patent/IL149005A0/xx active IP Right Grant
- 2000-10-06 US US10/089,991 patent/US6649651B1/en not_active Expired - Lifetime
- 2000-10-06 EP EP00966144A patent/EP1222192B8/en not_active Expired - Lifetime
- 2000-10-06 HU HU0203130A patent/HU228938B1/hu unknown
- 2000-10-06 OA OA1200200096A patent/OA12053A/en unknown
- 2000-10-06 BR BR0014602-1A patent/BR0014602A/pt not_active Application Discontinuation
- 2000-10-06 JP JP2001528184A patent/JP4951179B2/ja not_active Expired - Lifetime
- 2000-10-06 AP APAP/P/2002/002472A patent/AP1459A/en active
- 2000-10-06 NZ NZ518580A patent/NZ518580A/en not_active IP Right Cessation
- 2000-10-06 DE DE60039244T patent/DE60039244D1/de not_active Expired - Lifetime
- 2000-10-06 MX MXPA02003607A patent/MXPA02003607A/es active IP Right Grant
- 2000-10-06 PL PL354351A patent/PL204924B1/pl unknown
- 2000-10-06 AT AT00966144T patent/ATE398623T1/de not_active IP Right Cessation
- 2000-10-06 RU RU2002111657/04A patent/RU2247123C2/ru active
- 2000-10-06 SK SK570-2002A patent/SK287153B6/sk not_active IP Right Cessation
- 2000-10-06 CZ CZ20021419A patent/CZ300031B6/cs not_active IP Right Cessation
- 2000-10-06 DK DK00966144T patent/DK1222192T3/da active
- 2000-10-06 AU AU76638/00A patent/AU781656B2/en not_active Expired
- 2000-10-06 ES ES00966144T patent/ES2307533T3/es not_active Expired - Lifetime
- 2000-10-06 CA CA2386850A patent/CA2386850C/en not_active Expired - Lifetime
- 2000-10-06 KR KR1020027004284A patent/KR100792391B1/ko not_active Expired - Lifetime
2002
- 2002-04-04 NO NO20021598A patent/NO327996B1/no not_active IP Right Cessation
- 2002-04-04 ZA ZA200202655A patent/ZA200202655B/xx unknown
- 2002-04-04 IL IL149005A patent/IL149005A/en unknown
2003
- 2003-06-25 US US10/606,342 patent/US7157495B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2307533T3 (es)	2008-12-01
NO20021598D0 (no)	2002-04-04
NZ518580A (en)	2004-01-30
HUP0203130A3 (en)	2005-01-28
DE60039244D1 (de)	2008-07-31
ZA200202655B (en)	2003-09-23
IL149005A (en)	2006-12-31
US20050261364A1 (en)	2005-11-24
HK1054746A1 (en)	2003-12-12
WO2001025240A1 (en)	2001-04-12
SK5702002A3 (en)	2003-01-09
NO20021598L (no)	2002-05-29
AP1459A (en)	2005-08-22
EP1222192B8 (en)	2008-10-01
CA2386850C (en)	2010-03-30
PL354351A1 (en)	2004-01-12
NO327996B1 (no)	2009-11-02
AU781656B2 (en)	2005-06-02
BR0014602A (pt)	2002-06-11
AU7663800A (en)	2001-05-10
DK1222192T3 (da)	2008-10-20
KR100792391B1 (ko)	2008-01-08
HU228938B1 (hu)	2013-06-28
EP1222192A1 (en)	2002-07-17
CN1191256C (zh)	2005-03-02
ATE398623T1 (de)	2008-07-15
JP2003511383A (ja)	2003-03-25
AP2002002472A0 (en)	2002-06-30
KR20020067503A (ko)	2002-08-22
CN1407987A (zh)	2003-04-02
IL149005A0 (en)	2002-11-10
EP1222192B1 (en)	2008-06-18
CZ300031B6 (cs)	2009-01-14
CA2386850A1 (en)	2001-04-12
US6649651B1 (en)	2003-11-18
JP4951179B2 (ja)	2012-06-13
HUP0203130A2 (hu)	2003-01-28
US7157495B2 (en)	2007-01-02
MXPA02003607A (es)	2003-07-28
SK287153B6 (sk)	2010-01-07
CZ20021419A3 (cs)	2002-10-16
PL204924B1 (pl)	2010-02-26
RU2247123C2 (ru)	2005-02-27

Publication	Publication Date	Title
US6649651B1 (en)	2003-11-18	Hexahydrofuro[2,3-B]furan-3-yl-n{3[(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino]-1-benzyl-2-hydroxypropyl}carbamate as retroviral protease inhibitor
AU2003262561B2 (en)	2008-10-16	Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors
KR100872029B1 (ko)	2008-12-05	광범위 2-(치환된-아미노)-벤즈옥사졸 설폰아미드 ｈｉｖ프로테아제 저해제
EP1960404B1 (en)	2015-06-17	Substituted aminophenylsulfonamide compounds as hiv protease inhibitors
KR20050013549A (ko)	2005-02-04	광범위 스펙트럼의 치환된 벤즈이속사졸 설폰아미드ｈｉｖ 프로테아제 저해제
KR101327772B1 (ko)	2013-11-11	광범위 2-아미노-벤조티아졸 설폰아미드 ｈｉｖ 프로테아제 저해제
US7803836B2 (en)	2010-09-28	Aminophenylsulfonamide derivatives as HIV protease inhibitor
HK1054746B (en)	2005-12-09	Hexahydrofuro'2,3-b!furan-3-yl-n- {3'(1,3-benzodioxol -5- ylsulfonyl) (isobutyl) amino! -1-benzyl-2-hydroxypropyl} carbamate as retroviral protease inhibitor
IL163960A (en)	2013-08-29	Benzimidazoles Sulphonamides are broad-spectrum as vih protease inhibitors and as an overall preparation
IL172935A (en)	2012-09-24	Inhibitors of HIV penetration