OA12173A - Dual inhibitors of cholesterol ester and wax estersynthesis for sebaceous gland disorders. - Google Patents

Dual inhibitors of cholesterol ester and wax estersynthesis for sebaceous gland disorders. Download PDF

Info

Publication number: OA12173A
Authority: OA; OAPI
Prior art keywords: phenyl; acné; diisopropyl; acetyl; use according
Prior art date: 2000-02-02

Application number

OA1200200234A

Other languages

English (en)

Inventor

Reynold Homan

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-02

Filing date

2001-01-23

Publication date

2006-05-08

2001-01-23 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2006-05-08 Publication of OA12173A publication Critical patent/OA12173A/en

Links

208000015390 Sebaceous gland disease Diseases 0.000 title claims abstract description 22
239000003112 inhibitor Substances 0.000 title description 15
230000009977 dual effect Effects 0.000 title description 3
150000001840 cholesterol esters Chemical class 0.000 title description 2
150000001875 compounds Chemical class 0.000 claims abstract description 50
238000011282 treatment Methods 0.000 claims abstract description 32
PTQXTEKSNBVPQJ-UHFFFAOYSA-N Avasimibe Chemical compound CC(C)C1=CC(C(C)C)=CC(C(C)C)=C1CC(=O)NS(=O)(=O)OC1=C(C(C)C)C=CC=C1C(C)C PTQXTEKSNBVPQJ-UHFFFAOYSA-N 0.000 claims abstract description 31
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208000008742 seborrheic dermatitis Diseases 0.000 claims abstract description 4
208000009675 Perioral Dermatitis Diseases 0.000 claims abstract description 3
-1 2,4,6-triisopropyl-phenyl Chemical group 0.000 claims description 40
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235000011007 phosphoric acid Nutrition 0.000 description 1
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239000002798 polar solvent Substances 0.000 description 1
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239000011591 potassium Substances 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
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239000007909 solid dosage form Substances 0.000 description 1
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239000011550 stock solution Substances 0.000 description 1
230000009897 systematic effect Effects 0.000 description 1
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239000000454 talc Substances 0.000 description 1
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239000003981 vehicle Substances 0.000 description 1
239000011345 viscous material Substances 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

OA1200200234A 2000-02-02 2001-01-23 Dual inhibitors of cholesterol ester and wax estersynthesis for sebaceous gland disorders. OA12173A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US17977800P	2000-02-02	2000-02-02

Publications (1)

Publication Number	Publication Date
OA12173A true OA12173A (en)	2006-05-08

Family

ID=22657957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200200234A OA12173A (en)	2000-02-02	2001-01-23	Dual inhibitors of cholesterol ester and wax estersynthesis for sebaceous gland disorders.

Country Status (34)

Country	Link
US (2)	US6730703B2 (de)
EP (1)	EP1263421B1 (de)
JP (1)	JP2003531113A (de)
KR (1)	KR20020073574A (de)
CN (1)	CN1398182A (de)
AP (1)	AP2002002612A0 (de)
AT (1)	ATE295724T1 (de)
AU (1)	AU781563B2 (de)
BG (1)	BG107042A (de)
BR (1)	BR0107954A (de)
CA (1)	CA2398219A1 (de)
CR (1)	CR6712A (de)
DE (1)	DE60110897T2 (de)
DZ (1)	DZ3288A1 (de)
EA (1)	EA004255B1 (de)
EE (1)	EE200200429A (de)
ES (1)	ES2239145T3 (de)
GE (1)	GEP20043286B (de)
HR (1)	HRP20020717A2 (de)
HU (1)	HUP0301010A3 (de)
IL (1)	IL150865A0 (de)
IS (1)	IS6478A (de)
MA (1)	MA26872A1 (de)
MX (1)	MXPA02007309A (de)
NO (1)	NO20023659L (de)
NZ (1)	NZ520330A (de)
OA (1)	OA12173A (de)
PL (1)	PL357041A1 (de)
PT (1)	PT1263421E (de)
SK (1)	SK10972002A3 (de)
UA (1)	UA75345C2 (de)
WO (1)	WO2001056556A2 (de)
YU (1)	YU57502A (de)
ZA (1)	ZA200206075B (de)

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US20050031699A1 (en)	2003-06-26	2005-02-10	L'oreal	Porous particles loaded with cosmetically or pharmaceutically active compounds
ATE409470T1 (de)	2003-10-09	2008-10-15	Warner Lambert Co	Pharmazeutische zusammensetzungen mit malonamid- derivaten zur verringerung der talg-produktion
MX2007010374A (es)	2005-02-24	2007-09-25	Warner Lambert Co	Inhibidor de acat cristalino.
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FR2904002A1 (fr) *	2006-07-19	2008-01-25	Galderma Res & Dev S N C Snc	Modulateurs de la lanosterol synthetase dans le traitement de l'acne ou de l'hyperseborrhee
FR2938342A1 (fr) *	2008-11-13	2010-05-14	Galderma Res & Dev	Ciblage de modulateurs de ces1 et/ou ces3 dans le traitement de l'acne, d'une dermatite seborrheique ou de l'hyperseborrhee
EP2391342A2 (de)	2009-01-28	2011-12-07	Nanobio Corporation	Zusammensetzungen für behandlung und prophylaxe von akne, verfahren zur herstellung der zusammensetzungen und verwendungsverfahren dafür
US20210260055A1 (en) *	2018-06-21	2021-08-26	Dermavant Sciences GmbH	Topical formulations of dgat1 inhibitors and their methods of use

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2001
- 2001-01-23 HU HU0301010A patent/HUP0301010A3/hu unknown
- 2001-01-23 KR KR1020027009943A patent/KR20020073574A/ko not_active Ceased
- 2001-01-23 OA OA1200200234A patent/OA12173A/en unknown
- 2001-01-23 YU YU57502A patent/YU57502A/sh unknown
- 2001-01-23 DE DE60110897T patent/DE60110897T2/de not_active Expired - Fee Related
- 2001-01-23 CN CN01804520A patent/CN1398182A/zh active Pending
- 2001-01-23 ES ES01948936T patent/ES2239145T3/es not_active Expired - Lifetime
- 2001-01-23 SK SK1097-2002A patent/SK10972002A3/sk not_active Application Discontinuation
- 2001-01-23 EA EA200200764A patent/EA004255B1/ru not_active IP Right Cessation
- 2001-01-23 PT PT01948936T patent/PT1263421E/pt unknown
- 2001-01-23 DZ DZ013288A patent/DZ3288A1/fr active
- 2001-01-23 AU AU29718/01A patent/AU781563B2/en not_active Ceased
- 2001-01-23 WO PCT/US2001/002190 patent/WO2001056556A2/en not_active Ceased
- 2001-01-23 EP EP01948936A patent/EP1263421B1/de not_active Expired - Lifetime
- 2001-01-23 PL PL01357041A patent/PL357041A1/xx not_active Application Discontinuation
- 2001-01-23 BR BR0107954-9A patent/BR0107954A/pt not_active Application Discontinuation
- 2001-01-23 CA CA002398219A patent/CA2398219A1/en not_active Abandoned
- 2001-01-23 GE GEAP20016597A patent/GEP20043286B/en unknown
- 2001-01-23 UA UA2002076160A patent/UA75345C2/uk unknown
- 2001-01-23 AP APAP/P/2002/002612A patent/AP2002002612A0/en unknown
- 2001-01-23 NZ NZ520330A patent/NZ520330A/en unknown
- 2001-01-23 HR HR20020717A patent/HRP20020717A2/hr not_active Application Discontinuation
- 2001-01-23 US US10/182,847 patent/US6730703B2/en not_active Expired - Fee Related
- 2001-01-23 MX MXPA02007309A patent/MXPA02007309A/es active IP Right Grant
- 2001-01-23 IL IL15086501A patent/IL150865A0/xx unknown
- 2001-01-23 AT AT01948936T patent/ATE295724T1/de not_active IP Right Cessation
- 2001-01-23 EE EEP200200429A patent/EE200200429A/xx unknown
- 2001-01-23 JP JP2001556248A patent/JP2003531113A/ja active Pending
2002
- 2002-07-19 IS IS6478A patent/IS6478A/is unknown
- 2002-07-24 CR CR6712A patent/CR6712A/es not_active Application Discontinuation
- 2002-07-30 ZA ZA200206075A patent/ZA200206075B/en unknown
- 2002-08-01 NO NO20023659A patent/NO20023659L/no not_active Application Discontinuation
- 2002-08-01 MA MA26756A patent/MA26872A1/fr unknown
- 2002-08-29 BG BG107042A patent/BG107042A/bg unknown
2004
- 2004-02-06 US US10/773,354 patent/US20040161393A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1263421A2 (de)	2002-12-11
EP1263421B1 (de)	2005-05-18
NO20023659L (no)	2002-09-25
US6730703B2 (en)	2004-05-04
YU57502A (sh)	2006-01-16
AP2002002612A0 (en)	2002-09-30
DE60110897D1 (de)	2005-06-23
US20040161393A1 (en)	2004-08-19
IS6478A (is)	2002-07-19
PT1263421E (pt)	2005-08-31
EA200200764A1 (ru)	2002-12-26
ATE295724T1 (de)	2005-06-15
HUP0301010A3 (en)	2005-03-29
AU781563B2 (en)	2005-06-02
HRP20020717A2 (en)	2003-12-31
ES2239145T3 (es)	2005-09-16
DE60110897T2 (de)	2006-03-23
DZ3288A1 (en)	2001-08-09
HUP0301010A2 (hu)	2003-08-28
UA75345C2 (en)	2006-04-17
MXPA02007309A (es)	2002-11-29
CR6712A (es)	2004-01-14
BR0107954A (pt)	2002-10-22
ZA200206075B (en)	2003-10-30
CA2398219A1 (en)	2001-08-09
EA004255B1 (ru)	2004-02-26
IL150865A0 (en)	2003-02-12
MA26872A1 (fr)	2004-12-20
JP2003531113A (ja)	2003-10-21
AU2971801A (en)	2001-08-14
PL357041A1 (en)	2004-07-12
BG107042A (bg)	2003-04-30
NZ520330A (en)	2004-02-27
NO20023659D0 (no)	2002-08-01
US20030060507A1 (en)	2003-03-27
CN1398182A (zh)	2003-02-19
WO2001056556A2 (en)	2001-08-09
KR20020073574A (ko)	2002-09-27
WO2001056556A3 (en)	2002-03-07
EE200200429A (et)	2003-12-15
SK10972002A3 (sk)	2003-07-01
GEP20043286B (en)	2004-07-26

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CN115554184A (zh)	2023-01-03	一种延缓薁磺酸钠氧化的方法
HK1051813A (en)	2003-08-22	Dual inhibitors of cholesteryl ester and wax ester synthesis for sebaceous gland disorders
KR20030084484A (ko)	2003-11-01	여드름 피부용 화장료 조성물