OA12513A - Novel composition and use. - Google Patents

Novel composition and use. Download PDF

Info

Publication number: OA12513A
Authority: OA; OAPI
Prior art keywords: composition according; thiazolidinedione; carrier; compound; composition
Prior art date: 1999-11-16

Application number

OA1200200145A

Other languages

English (en)

Inventor

Karen Lewis

Nicola Jayne Lilliott

Donald Colin Mackenzie

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-16

Filing date

2000-11-16

Publication date

2006-05-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27447849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA12513(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-11-16 Priority claimed from GBGB9927120.7A external-priority patent/GB9927120D0/en

1999-11-16 Priority claimed from GBGB9927119.9A external-priority patent/GB9927119D0/en

2000-05-31 Priority claimed from GB0013240A external-priority patent/GB0013240D0/en

2000-05-31 Priority claimed from GB0013236A external-priority patent/GB0013236D0/en

2000-11-16 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2006-05-29 Publication of OA12513A publication Critical patent/OA12513A/en

Links

239000000203 mixture Substances 0.000 title claims description 128
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ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 claims abstract description 39
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238000012544 monitoring process Methods 0.000 description 1
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SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
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WVWZXTJUCNEUAE-UHFFFAOYSA-M potassium;1,2-bis(ethenyl)benzene;2-methylprop-2-enoate Chemical compound [K+].CC(=C)C([O-])=O.C=CC1=CC=CC=C1C=C WVWZXTJUCNEUAE-UHFFFAOYSA-M 0.000 description 1
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239000008117 stearic acid Substances 0.000 description 1
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Classifications

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

OA1200200145A 1999-11-16 2000-11-16 Novel composition and use. OA12513A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9927120.7A GB9927120D0 (en)	1999-11-16	1999-11-16	Novel composition and use
GBGB9927119.9A GB9927119D0 (en)	1999-11-16	1999-11-16	Novel composition and use
GB0013240A GB0013240D0 (en)	2000-05-31	2000-05-31	Novel composition and use
GB0013236A GB0013236D0 (en)	2000-05-31	2000-05-31	Novel composition and use

Publications (1)

Publication Number	Publication Date
OA12513A true OA12513A (en)	2006-05-29

Family

ID=27447849

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200200145A OA12513A (en)	1999-11-16	2000-11-16	Novel composition and use.

Country Status (40)

Country	Link
US (1)	US8236345B2 (sr)
EP (3)	EP1231918B1 (sr)
JP (2)	JP4865975B2 (sr)
KR (1)	KR100760063B1 (sr)
CN (1)	CN1222290C (sr)
AP (1)	AP1389A (sr)
AR (2)	AR030920A1 (sr)
AT (1)	ATE292466T1 (sr)
AU (3)	AU775654B2 (sr)
BG (1)	BG65616B1 (sr)
BR (1)	BR0015605A (sr)
CA (1)	CA2388846A1 (sr)
CO (1)	CO5300392A1 (sr)
CZ (1)	CZ302500B6 (sr)
DE (1)	DE60019329T2 (sr)
DK (1)	DK1231918T3 (sr)
DZ (1)	DZ3251A1 (sr)
EA (1)	EA004878B1 (sr)
ES (1)	ES2240199T3 (sr)
HK (1)	HK1049788B (sr)
HR (1)	HRP20020416B1 (sr)
HU (1)	HU229960B1 (sr)
IL (3)	IL149618A0 (sr)
MA (1)	MA25567A1 (sr)
ME (1)	ME00318B (sr)
MX (1)	MXPA02005005A (sr)
MY (1)	MY125516A (sr)
NO (1)	NO329926B1 (sr)
NZ (1)	NZ518946A (sr)
OA (1)	OA12513A (sr)
PE (1)	PE20011011A1 (sr)
PL (1)	PL200943B1 (sr)
PT (1)	PT1231918E (sr)
RS (1)	RS51343B (sr)
SI (1)	SI1231918T1 (sr)
SK (1)	SK286985B6 (sr)
TW (1)	TWI240626B (sr)
UA (1)	UA73150C2 (sr)
UY (1)	UY26439A1 (sr)
WO (1)	WO2001035941A2 (sr)

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2000
- 2000-11-15 MY MYPI20005360A patent/MY125516A/en unknown
- 2000-11-15 AR ARP000106019A patent/AR030920A1/es active IP Right Grant
- 2000-11-16 IL IL14961800A patent/IL149618A0/xx unknown
- 2000-11-16 SI SI200030697T patent/SI1231918T1/xx unknown
- 2000-11-16 BR BR0015605-1A patent/BR0015605A/pt not_active Application Discontinuation
- 2000-11-16 AU AU14040/01A patent/AU775654B2/en not_active Expired
- 2000-11-16 WO PCT/GB2000/004368 patent/WO2001035941A2/en not_active Ceased
- 2000-11-16 NZ NZ518946A patent/NZ518946A/en not_active IP Right Cessation
- 2000-11-16 UA UA2002064826A patent/UA73150C2/uk unknown
- 2000-11-16 CZ CZ20021679A patent/CZ302500B6/cs not_active IP Right Cessation
- 2000-11-16 OA OA1200200145A patent/OA12513A/en unknown
- 2000-11-16 CA CA002388846A patent/CA2388846A1/en not_active Abandoned
- 2000-11-16 KR KR1020027006271A patent/KR100760063B1/ko not_active Expired - Lifetime
- 2000-11-16 AP APAP/P/2002/002505A patent/AP1389A/en active
- 2000-11-16 SK SK679-2002A patent/SK286985B6/sk not_active IP Right Cessation
- 2000-11-16 RS YUP-388/02A patent/RS51343B/sr unknown
- 2000-11-16 HU HU0204122A patent/HU229960B1/hu unknown
- 2000-11-16 DZ DZ003251A patent/DZ3251A1/fr active
- 2000-11-16 AT AT00976156T patent/ATE292466T1/de active
- 2000-11-16 CN CNB008178224A patent/CN1222290C/zh not_active Expired - Lifetime
- 2000-11-16 EP EP00976156A patent/EP1231918B1/en not_active Expired - Lifetime
- 2000-11-16 DE DE60019329T patent/DE60019329T2/de not_active Expired - Lifetime
- 2000-11-16 EP EP07120386A patent/EP1913945A3/en not_active Withdrawn
- 2000-11-16 HK HK03100745.5A patent/HK1049788B/en not_active IP Right Cessation
- 2000-11-16 MX MXPA02005005A patent/MXPA02005005A/es active IP Right Grant
- 2000-11-16 PT PT00976156T patent/PT1231918E/pt unknown
- 2000-11-16 PL PL355331A patent/PL200943B1/pl unknown
- 2000-11-16 ME MEP-2008-340A patent/ME00318B/me unknown
- 2000-11-16 DK DK00976156T patent/DK1231918T3/da active
- 2000-11-16 HR HR20020416A patent/HRP20020416B1/xx not_active IP Right Cessation
- 2000-11-16 ES ES00976156T patent/ES2240199T3/es not_active Expired - Lifetime
- 2000-11-16 UY UY26439A patent/UY26439A1/es not_active IP Right Cessation
- 2000-11-16 EP EP04078538A patent/EP1520581A1/en not_active Withdrawn
- 2000-11-16 EA EA200200571A patent/EA004878B1/ru not_active IP Right Cessation
- 2000-11-16 PE PE2000001226A patent/PE20011011A1/es not_active Application Discontinuation
- 2000-11-16 JP JP2001537934A patent/JP4865975B2/ja not_active Expired - Lifetime
- 2000-11-20 CO CO00088045A patent/CO5300392A1/es not_active Application Discontinuation
- 2000-12-04 TW TW089125730A patent/TWI240626B/zh not_active IP Right Cessation
2002
- 2002-05-13 IL IL149618A patent/IL149618A/en unknown
- 2002-05-15 MA MA26640A patent/MA25567A1/fr unknown
- 2002-05-15 NO NO20022334A patent/NO329926B1/no not_active IP Right Cessation
- 2002-05-29 BG BG106747A patent/BG65616B1/bg unknown
2004
- 2004-11-04 AU AU2004226955A patent/AU2004226955B2/en not_active Expired
2006
- 2006-12-05 AR ARP060105370A patent/AR057970A2/es active IP Right Grant
2007
- 2007-07-18 US US11/779,546 patent/US8236345B2/en not_active Expired - Fee Related
2008
- 2008-03-17 IL IL190220A patent/IL190220A0/en unknown
- 2008-08-18 AU AU2008207375A patent/AU2008207375A1/en not_active Abandoned
2011
- 2011-08-11 JP JP2011175883A patent/JP5282130B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP5282130B2 (ja)	2013-09-04
JP4865975B2 (ja)	2012-02-01
ME00318B (me)	2011-05-10
EP1520581A1 (en)	2005-04-06
JP2011252007A (ja)	2011-12-15
DE60019329D1 (de)	2005-05-12
DZ3251A1 (fr)	2001-05-25
CO5300392A1 (es)	2003-07-31
BR0015605A (pt)	2002-07-09
CA2388846A1 (en)	2001-05-25
JP2003514012A (ja)	2003-04-15
AU775654B2 (en)	2004-08-12
IL149618A0 (en)	2002-12-01
MA25567A1 (fr)	2002-10-01
AP2002002505A0 (en)	2002-06-30
NO329926B1 (no)	2011-01-24
SK286985B6 (sk)	2009-08-06
YU38802A (sh)	2005-03-15
IL149618A (en)	2008-07-08
BG65616B1 (bg)	2009-03-31
AU2004226955B2 (en)	2008-08-28
AR030920A1 (es)	2003-09-03
PL200943B1 (pl)	2009-02-27
DE60019329T2 (de)	2006-03-09
NO20022334L (no)	2002-07-09
RS51343B (sr)	2011-02-28
AU2004226955A1 (en)	2004-12-02
WO2001035941A2 (en)	2001-05-25
ATE292466T1 (de)	2005-04-15
HUP0204122A2 (hu)	2003-03-28
SK6792002A3 (en)	2002-09-10
KR20030019300A (ko)	2003-03-06
CN1414852A (zh)	2003-04-30
AR057970A2 (es)	2007-12-26
NZ518946A (en)	2003-10-31
MEP34008A (en)	2011-02-10
HUP0204122A3 (en)	2006-01-30
KR100760063B1 (ko)	2007-09-18
HRP20020416B1 (hr)	2011-04-30
EA004878B1 (ru)	2004-08-26
CZ302500B6 (cs)	2011-06-22
NO20022334D0 (no)	2002-05-15
AP1389A (en)	2005-04-14
EP1231918B1 (en)	2005-04-06
EP1913945A2 (en)	2008-04-23
EP1231918A2 (en)	2002-08-21
WO2001035941A3 (en)	2002-05-23
ES2240199T3 (es)	2005-10-16
EA200200571A1 (ru)	2002-12-26
PE20011011A1 (es)	2001-10-28
HU229960B1 (hu)	2015-03-30
US20070275054A1 (en)	2007-11-29
TWI240626B (en)	2005-10-01
WO2001035941A8 (en)	2002-08-29
MXPA02005005A (es)	2003-10-14
UY26439A1 (es)	2001-07-31
EP1913945A3 (en)	2008-04-30
PL355331A1 (en)	2004-04-19
HRP20020416A2 (en)	2004-08-31
AU2008207375A1 (en)	2008-09-11
HK1049788A1 (en)	2003-05-30
CN1222290C (zh)	2005-10-12
MY125516A (en)	2006-08-30
IL190220A0 (en)	2008-11-03
AU1404001A (en)	2001-05-30
SI1231918T1 (en)	2005-08-31
PT1231918E (pt)	2005-08-31
DK1231918T3 (da)	2005-08-01
HK1049788B (en)	2005-11-04
US8236345B2 (en)	2012-08-07
BG106747A (en)	2003-01-31
UA73150C2 (uk)	2005-06-15

Publication	Publication Date	Title
OA12513A (en)	2006-05-29	Novel composition and use.
AU768994B2 (en)	2004-01-15	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
US20040081697A1 (en)	2004-04-29	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
KR100732599B1 (ko)	2007-06-27	조절 방출형 인슐린 감작제용 제약 조성물
ZA200203865B (en)	2002-11-22	Novel composition and use.
HK1076045A (en)	2006-01-06	Composition based on a thiazolidinedione and metformin and its use
HK1116681A (en)	2009-01-02	Composition based on a thiazolidinedione and metformin and its use
AU2757202A (en)	2002-05-16	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
ZA200103843B (en)	2002-05-14	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent.
AU2005200704A1 (en)	2005-03-17	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
AU2008203540A1 (en)	2008-08-28	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
HK1106135A (en)	2008-03-07	Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
HK1127277A (en)	2009-09-25	Novel modified release composition and use