PH12014500925A1 - Therapeutic combinations and methods of treating melanoma - Google Patents

Therapeutic combinations and methods of treating melanoma

Info

Publication number
PH12014500925A1
PH12014500925A1 PH1/2014/500925A PH12014500925A PH12014500925A1 PH 12014500925 A1 PH12014500925 A1 PH 12014500925A1 PH 12014500925 A PH12014500925 A PH 12014500925A PH 12014500925 A1 PH12014500925 A1 PH 12014500925A1
Authority
PH
Philippines
Prior art keywords
methods
therapeutic combinations
treating melanoma
melanoma
combinations
Prior art date
Application number
PH1/2014/500925A
Other languages
English (en)
Inventor
Jyoti Asundi
Suzanna Clark
Paul Polakis
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PH12014500925A1 publication Critical patent/PH12014500925A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PH1/2014/500925A 2011-10-28 2012-10-24 Therapeutic combinations and methods of treating melanoma PH12014500925A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161552893P 2011-10-28 2011-10-28
US201261678978P 2012-08-02 2012-08-02
PCT/US2012/061533 WO2013063001A1 (en) 2011-10-28 2012-10-24 Therapeutic combinations and methods of treating melanoma

Publications (1)

Publication Number Publication Date
PH12014500925A1 true PH12014500925A1 (en) 2014-06-09

Family

ID=48168400

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2014/500925A PH12014500925A1 (en) 2011-10-28 2012-10-24 Therapeutic combinations and methods of treating melanoma

Country Status (19)

Country Link
EP (1) EP2776051A4 (es)
JP (2) JP6251682B2 (es)
KR (1) KR20140097205A (es)
CN (1) CN104039340B (es)
AR (1) AR088509A1 (es)
AU (1) AU2012328980A1 (es)
BR (1) BR112014009953A2 (es)
CA (1) CA2850034A1 (es)
CL (1) CL2014001092A1 (es)
CO (1) CO7151543A2 (es)
EA (1) EA201490879A1 (es)
IL (1) IL232135A0 (es)
IN (1) IN2014CN03062A (es)
MX (1) MX2014004991A (es)
PE (1) PE20142312A1 (es)
PH (1) PH12014500925A1 (es)
SG (1) SG11201401815XA (es)
TW (1) TW201325613A (es)
WO (1) WO2013063001A1 (es)

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EP2739358B1 (en) 2011-08-01 2018-11-28 F.Hoffmann-La Roche Ag Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors
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MX2017000546A (es) 2014-07-15 2017-03-08 Genentech Inc Composiciones para el tratamiento del cancer mediante el uso de antagonistas de union al eje de pd-1 e inhibidores de mek.
WO2016055907A1 (en) * 2014-10-10 2016-04-14 Pfizer Inc. Synergistic auristatin combinations
MX2018001507A (es) * 2015-08-03 2018-09-18 Enb Therapeutics Llc Composiciones y metodos para tratar cánceres asociados con la activacion del etbr.
FR3053042B1 (fr) 2016-06-24 2018-08-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Anticorps dirige contre le sous-type b des recepteurs aux endothelines et ses utilisations
CN110291089B (zh) 2017-01-17 2022-05-27 海帕瑞吉尼克斯股份有限公司 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂
EP4688830A1 (en) 2023-04-07 2026-02-11 Commissariat à l'Energie Atomique et aux Energies Alternatives Use of antibody against the endothelin receptor b for diagnostic and therapeutic applications
FR3155709A1 (fr) * 2023-11-27 2025-05-30 Skymab Biotherapeutics Conjugue anticorps-medicament et ses utilisations
FR3155708A1 (fr) * 2023-11-27 2025-05-30 Skymab Biotherapeutics Conjugue anticorps-medicament et ses utilisations
EP4721765A1 (en) 2024-10-04 2026-04-08 Commissariat à l'Energie Atomique et aux Energies Alternatives Bi-functionalized antibody conjugates against the endothelin receptor b

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KR20140097205A (ko) 2014-08-06
AR088509A1 (es) 2014-06-11
JP2014532648A (ja) 2014-12-08
IL232135A0 (en) 2014-05-28
JP6251682B2 (ja) 2017-12-20
BR112014009953A2 (pt) 2017-12-05
CA2850034A1 (en) 2013-05-02
CO7151543A2 (es) 2014-12-29
SG11201401815XA (en) 2014-05-29
EP2776051A4 (en) 2015-06-17
PE20142312A1 (es) 2015-01-25
EA201490879A1 (ru) 2014-08-29
CL2014001092A1 (es) 2014-07-25
AU2012328980A1 (en) 2014-04-24
IN2014CN03062A (es) 2015-07-31
CN104039340B (zh) 2017-04-05
WO2013063001A1 (en) 2013-05-02
TW201325613A (zh) 2013-07-01
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EP2776051A1 (en) 2014-09-17
MX2014004991A (es) 2014-05-22

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