PH26811A - Monohydrate and solvates of a B-lactam antibiotics - Google Patents

Monohydrate and solvates of a B-lactam antibiotics Download PDF

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Publication number
PH26811A
PH26811A PH37637A PH37637A PH26811A PH 26811 A PH26811 A PH 26811A PH 37637 A PH37637 A PH 37637A PH 37637 A PH37637 A PH 37637A PH 26811 A PH26811 A PH 26811A
Authority
PH
Philippines
Prior art keywords
formula
compound
dmf
solvate
crystalline
Prior art date
Application number
PH37637A
Other languages
English (en)
Inventor
John Brennan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PH26811A publication Critical patent/PH26811A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH37637A 1987-10-07 1988-10-04 Monohydrate and solvates of a B-lactam antibiotics PH26811A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10576287A 1987-10-07 1987-10-07

Publications (1)

Publication Number Publication Date
PH26811A true PH26811A (en) 1992-11-05

Family

ID=22307652

Family Applications (1)

Application Number Title Priority Date Filing Date
PH37637A PH26811A (en) 1987-10-07 1988-10-04 Monohydrate and solvates of a B-lactam antibiotics

Country Status (24)

Country Link
EP (1) EP0311365A1 (ro)
JP (1) JPH02270871A (ro)
KR (1) KR890006643A (ro)
CN (1) CN1032442A (ro)
AU (1) AU605635B2 (ro)
BG (1) BG47035A3 (ro)
CS (1) CS270593B2 (ro)
DD (1) DD280112A5 (ro)
DK (1) DK553888A (ro)
FI (1) FI884555L (ro)
HU (1) HU205112B (ro)
IL (1) IL87904A0 (ro)
MX (1) MX13276A (ro)
MY (1) MY103554A (ro)
NO (1) NO884417L (ro)
NZ (1) NZ226451A (ro)
OA (1) OA09017A (ro)
PH (1) PH26811A (ro)
PL (2) PL159766B1 (ro)
PT (1) PT88663B (ro)
RO (2) RO102423B1 (ro)
RU (1) RU1776260C (ro)
YU (1) YU46700B (ro)
ZA (1) ZA887408B (ro)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate
IL101748A0 (en) * 1991-05-10 1992-12-30 Lilly Co Eli Process for preparing doubly blocked 1-carba(1-dethia)-3-cephem-4-carboxylic acids

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate

Also Published As

Publication number Publication date
RO102423B1 (en) 1992-08-01
PT88663A (pt) 1989-07-31
BG47035A3 (bg) 1990-04-16
PL275092A1 (en) 1989-05-16
EP0311365A1 (en) 1989-04-12
MX13276A (es) 1993-11-01
AU2337188A (en) 1989-04-13
OA09017A (fr) 1991-03-31
IL87904A0 (en) 1989-03-31
PT88663B (pt) 1993-10-29
FI884555A7 (fi) 1989-04-08
MY103554A (en) 1993-07-31
PL163113B1 (pl) 1994-02-28
DK553888A (da) 1989-04-08
FI884555A0 (fi) 1988-10-04
CS270593B2 (en) 1990-07-12
KR890006643A (ko) 1989-06-15
RU1776260C (ru) 1992-11-15
AU605635B2 (en) 1991-01-17
ZA887408B (en) 1990-06-27
JPH02270871A (ja) 1990-11-05
HUT48883A (en) 1989-07-28
CS666588A2 (en) 1989-11-14
NO884417L (no) 1989-04-10
PL159766B1 (pl) 1993-01-29
NZ226451A (en) 1990-10-26
YU46700B (sh) 1994-04-05
DD280112A5 (de) 1990-06-27
HU205112B (en) 1992-03-30
FI884555L (fi) 1989-04-08
NO884417D0 (no) 1988-10-05
YU184688A (en) 1990-04-30
DK553888D0 (da) 1988-10-04
RO105809B1 (ro) 1992-12-30
CN1032442A (zh) 1989-04-19

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