PH30054A - Substitution analogues of magainin peptides - Google Patents

Substitution analogues of magainin peptides

Info

Publication number
PH30054A
PH30054A PH40802A PH40802A PH30054A PH 30054 A PH30054 A PH 30054A PH 40802 A PH40802 A PH 40802A PH 40802 A PH40802 A PH 40802A PH 30054 A PH30054 A PH 30054A
Authority
PH
Philippines
Prior art keywords
magainin
magainin peptides
substitution analogues
analogues
substitution
Prior art date
Application number
PH40802A
Other languages
English (en)
Inventor
Richard A Houghten
Julio H Cuervo
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Priority to PH45486A priority Critical patent/PH30219A/en
Priority to PH45488A priority patent/PH30218A/en
Priority to PH45487A priority patent/PH30410A/en
Publication of PH30054A publication Critical patent/PH30054A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PH40802A 1989-07-07 1990-07-06 Substitution analogues of magainin peptides PH30054A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PH45486A PH30219A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of sperms
PH45488A PH30218A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of virus
PH45487A PH30410A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of tumor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37675489A 1989-07-07 1989-07-07

Publications (1)

Publication Number Publication Date
PH30054A true PH30054A (en) 1996-11-08

Family

ID=23486335

Family Applications (4)

Application Number Title Priority Date Filing Date
PH40802A PH30054A (en) 1989-07-07 1990-07-06 Substitution analogues of magainin peptides
PH45488A PH30218A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of virus
PH45486A PH30219A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of sperms
PH45487A PH30410A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of tumor

Family Applications After (3)

Application Number Title Priority Date Filing Date
PH45488A PH30218A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of virus
PH45486A PH30219A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of sperms
PH45487A PH30410A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of tumor

Country Status (16)

Country Link
EP (4) EP0437556B1 (fr)
JP (1) JP2854970B2 (fr)
CN (1) CN1055480C (fr)
AT (1) ATE146188T1 (fr)
AU (1) AU650236B2 (fr)
CA (1) CA2020663C (fr)
DE (1) DE69029377T2 (fr)
DK (1) DK0437556T3 (fr)
ES (1) ES2095255T3 (fr)
IE (1) IE63842B1 (fr)
IL (1) IL94939A (fr)
PH (4) PH30054A (fr)
PT (1) PT94625B (fr)
SG (1) SG47913A1 (fr)
WO (1) WO1991000869A1 (fr)
ZA (1) ZA905203B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991000869A1 (fr) * 1989-07-07 1991-01-24 Scripps Clinic And Research Foundation Analogues de substitution des peptides de la magainine
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
AU648140B2 (en) * 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
WO1992022317A1 (fr) * 1991-06-12 1992-12-23 Magainin Pharmaceuticals, Inc. Composition de peptides biologiquement actifs presentant des substitutions au niveau de leur terminaison c et traitement a l'aide de ces peptides
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
CN101928340A (zh) * 2009-12-24 2010-12-29 深圳市圣西马生物技术有限公司 一组抗菌肽衍生物及其应用
CN104710523B (zh) * 2013-12-11 2017-12-29 华东理工大学 对铜绿假单胞菌具有抗菌性能的Magainin肽修饰物及其制备方法
KR20180022971A (ko) * 2015-07-02 2018-03-06 다나-파버 캔서 인스티튜트 인크. 안정화된 항미생물성 펩티드
WO2017151617A1 (fr) 2016-02-29 2017-09-08 Dana-Farber Cancer Institute, Inc. Peptides antimicrobiens agrafés à ciblage intracellulaire pour traiter une infection
CA3067047A1 (fr) * 2017-07-19 2019-01-24 Dana-Farber Cancer Institute, Inc. Peptides antimicrobiens stabilises pour le traitement d'infections bacteriennes resistantes aux antibiotiques
CN111892646B (zh) * 2020-08-13 2023-05-02 中国人民解放军军事科学院军事医学研究院 抗菌肽衍生物及其在制备抗细菌感染药物中的应用
CN112625092B (zh) * 2021-01-13 2023-03-28 兰州大学 一种基于polybia-MPI的抗菌多肽化合物及其合成与应用
CN114634553B (zh) * 2022-04-27 2024-03-08 贵州医科大学 阳离子肽c9及其应用
CN120081951B (zh) * 2025-03-06 2025-09-30 辽宁波尔莱特农牧实业集团有限公司 一种抗菌肽Magainin 2-hEGF融合蛋白及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU609118B2 (en) * 1987-03-04 1991-04-26 United States of America, as represented by the Secretary, U.S. Department of Commerce, The New synthetic bioactive compounds and method of producing bioactive effect
US4810777A (en) 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds
WO1991000869A1 (fr) * 1989-07-07 1991-01-24 Scripps Clinic And Research Foundation Analogues de substitution des peptides de la magainine

Also Published As

Publication number Publication date
ZA905203B (en) 1991-05-29
EP0751149A3 (fr) 1997-07-02
EP0437556B1 (fr) 1996-12-11
JP2854970B2 (ja) 1999-02-10
EP0437556A1 (fr) 1991-07-24
JPH04506801A (ja) 1992-11-26
AU650236B2 (en) 1994-06-16
ATE146188T1 (de) 1996-12-15
EP0751149A2 (fr) 1997-01-02
IE63842B1 (en) 1995-06-14
ES2095255T3 (es) 1997-02-16
PH30219A (en) 1997-02-05
DE69029377T2 (de) 1997-06-19
SG47913A1 (en) 1998-04-17
PT94625A (pt) 1991-03-20
IL94939A (en) 1996-12-05
DK0437556T3 (da) 1996-12-30
DE69029377D1 (de) 1997-01-23
CN1049166A (zh) 1991-02-13
IE902476A1 (en) 1991-02-13
CN1055480C (zh) 2000-08-16
AU5945490A (en) 1991-02-06
WO1991000869A1 (fr) 1991-01-24
EP0751148A3 (fr) 1997-07-02
CA2020663C (fr) 1999-12-07
EP0751148A2 (fr) 1997-01-02
PT94625B (pt) 1997-03-31
PH30218A (en) 1997-02-05
EP0761684A2 (fr) 1997-03-12
PH30410A (en) 1997-05-09
CA2020663A1 (fr) 1991-01-08
EP0437556A4 (en) 1992-05-20
IL94939A0 (en) 1991-06-10
EP0761684A3 (fr) 1997-07-02

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