PH30413A - Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides - Google Patents

Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides

Info

Publication number: PH30413A
Authority: PH; Philippines
Prior art keywords: azabicyclo; endo; dihydro; oct; methyl
Prior art date: 1992-03-26

Application number

PH45858A

Other languages

English (en)

Inventor

Enzo Cereda

Antoine Ezhaya

Marco Turconi

Enrica Dubini

Gracia Maffione

Original Assignee

Boehringer Ingelheim Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-26

Filing date

1993-03-11

Publication date

1997-05-09

1992-03-26 Priority claimed from ITMI920720A external-priority patent/IT1254562B/it

1992-03-26 Priority claimed from ITMI920723A external-priority patent/IT1254565B/it

1993-03-11 Application filed by Boehringer Ingelheim Italia filed Critical Boehringer Ingelheim Italia

1997-05-09 Publication of PH30413A publication Critical patent/PH30413A/en

Links

YLEIFZAVNWDOBM-ZTNXSLBXSA-N ac1l9hc7 Chemical compound C([C@H]12)C[C@@H](C([C@@H](O)CC3)(C)C)[C@@]43C[C@@]14CC[C@@]1(C)[C@@]2(C)C[C@@H]2O[C@]3(O)[C@H](O)C(C)(C)O[C@@H]3[C@@H](C)[C@H]12 YLEIFZAVNWDOBM-ZTNXSLBXSA-N 0.000 abstract 1
SRVFFFJZQVENJC-IHRRRGAJSA-N aloxistatin Chemical compound CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C SRVFFFJZQVENJC-IHRRRGAJSA-N 0.000 abstract 1
150000004682 monohydrates Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

PH45858A 1992-03-26 1993-03-11 Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides PH30413A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITMI920720A IT1254562B (it)	1992-03-26	1992-03-26	Forma cristallina dell'endo-3-etil-2,3-diidro-n-(8-metil-8-azabiciclo (3.2.1) ott-3-il)- 2-oxo-1h-benzimidazolo-1-carbossamide cloridrato
ITMI920723A IT1254565B (it)	1992-03-26	1992-03-26	Forma cristallina dell'endo-2,3-diidro-n-(8 metil-8-azabiciclo-(3.2.1) ott-3-il)-2-oxo-1h-benzimidazolo-1-carbossamide cloridrato

Publications (1)

Publication Number	Publication Date
PH30413A true PH30413A (en)	1997-05-09

Family

ID=26330860

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH45858A PH30413A (en)	1992-03-26	1993-03-11	Crystalline forms of endo-2,3-dihydro-n-(8-methyl)-8-azabicyclo-(3,2,1)oct-3-yl)-2-oxo-1h-benzimidazole-1-carboxamides

Country Status (27)

Country	Link
US (1)	US5468758A (de)
EP (1)	EP0567767B1 (de)
JP (1)	JP3279707B2 (de)
AT (1)	ATE169016T1 (de)
AU (1)	AU654082B2 (de)
BR (1)	BR1100564A (de)
CA (1)	CA2092510C (de)
CZ (1)	CZ286590B6 (de)
DE (1)	DE69319955T2 (de)
DK (1)	DK0567767T3 (de)
ES (1)	ES2118846T3 (de)
FI (1)	FI113472B (de)
HR (1)	HRP930479B1 (de)
HU (2)	HU211075B (de)
IL (1)	IL105143A (de)
MX (1)	MX9301668A (de)
NO (1)	NO300975B1 (de)
NZ (1)	NZ247234A (de)
PH (1)	PH30413A (de)
PL (1)	PL172890B1 (de)
RU (1)	RU2125054C1 (de)
SG (1)	SG43225A1 (de)
SI (1)	SI9300150B (de)
SK (1)	SK280555B6 (de)
TW (1)	TW385310B (de)
UA (1)	UA37179C2 (de)
UY (2)	UY25938A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2240637T3 (es)	1996-01-17	2005-10-16	Ricoh Company, Ltd.	Aparato de fijacion para un aparato de formacion de imagenes.
JPH1039679A (ja) *	1996-05-24	1998-02-13	Ricoh Co Ltd	定着装置
PE20001420A1 (es)	1998-12-23	2000-12-18	Pfizer	Moduladores de ccr5
US8697722B2 (en) *	2007-11-02	2014-04-15	Sri International	Nicotinic acetylcholine receptor modulators
RU2560729C2 (ru) *	2010-01-11	2015-08-20	АСТРАЕА ТЕРАПЕУТИКС, ЭлЭлСи	Модуляторы никотиновых ацетилхолиновых рецепторов

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4136189A (en) *	1975-09-16	1979-01-23	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T.	2-(5-nitro-furfurylidene)-amino-benzimidoles and fungicidal compositions containing the same
IT1231413B (it) *	1987-09-23	1991-12-04	Angeli Inst Spa	Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht
US5223511A (en) *	1987-09-23	1993-06-29	Boehringer Ingelheim Italia S.P.A.	Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists
GB9121835D0 (en) *	1991-10-15	1991-11-27	Smithkline Beecham Plc	Pharmaceuticals
PH31171A (en) *	1992-02-04	1998-03-20	Esai Co Ltd	Aminobenzonic acid derivatives useful for treatinggastrointestinal conditions.

1993
- 1993-03-11 PH PH45858A patent/PH30413A/en unknown
- 1993-03-19 CZ CZ1993443A patent/CZ286590B6/cs not_active IP Right Cessation
- 1993-03-19 AT AT93104564T patent/ATE169016T1/de active
- 1993-03-19 EP EP93104564A patent/EP0567767B1/de not_active Expired - Lifetime
- 1993-03-19 DE DE69319955T patent/DE69319955T2/de not_active Expired - Lifetime
- 1993-03-19 DK DK93104564T patent/DK0567767T3/da active
- 1993-03-19 SG SG1996005867A patent/SG43225A1/en unknown
- 1993-03-19 ES ES93104564T patent/ES2118846T3/es not_active Expired - Lifetime
- 1993-03-22 SK SK226-93A patent/SK280555B6/sk not_active IP Right Cessation
- 1993-03-23 HR HRMI92A000723A patent/HRP930479B1/xx not_active IP Right Cessation
- 1993-03-24 AU AU35413/93A patent/AU654082B2/en not_active Ceased
- 1993-03-24 NZ NZ247234A patent/NZ247234A/en not_active IP Right Cessation
- 1993-03-24 IL IL10514393A patent/IL105143A/en not_active IP Right Cessation
- 1993-03-24 TW TW082102205A patent/TW385310B/zh not_active IP Right Cessation
- 1993-03-25 MX MX9301668A patent/MX9301668A/es not_active IP Right Cessation
- 1993-03-25 HU HU9300868A patent/HU211075B/hu not_active IP Right Cessation
- 1993-03-25 CA CA002092510A patent/CA2092510C/en not_active Expired - Lifetime
- 1993-03-25 PL PL93298263A patent/PL172890B1/pl not_active IP Right Cessation
- 1993-03-25 JP JP06649293A patent/JP3279707B2/ja not_active Expired - Lifetime
- 1993-03-25 FI FI931329A patent/FI113472B/fi not_active IP Right Cessation
- 1993-03-25 RU RU93004710A patent/RU2125054C1/ru not_active IP Right Cessation
- 1993-03-25 NO NO931112A patent/NO300975B1/no not_active IP Right Cessation
- 1993-03-26 SI SI9300150A patent/SI9300150B/sl not_active IP Right Cessation
- 1993-06-08 UA UA93002686A patent/UA37179C2/uk unknown
1994
- 1994-06-22 US US08/264,104 patent/US5468758A/en not_active Expired - Lifetime
1995
- 1995-06-30 HU HU95P/P00677P patent/HU211131A9/hu unknown
1997
- 1997-05-13 BR BR1100564-5A patent/BR1100564A/pt active IP Right Grant
2000
- 2000-01-17 UY UY25938A patent/UY25938A1/es unknown
- 2000-01-17 UY UY25939A patent/UY25939A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
MX9301668A (es)	1993-09-01
SK22693A3 (en)	1993-11-10
NO931112D0 (no)	1993-03-25
UA37179C2 (uk)	2001-05-15
JPH0673053A (ja)	1994-03-15
FI113472B (fi)	2004-04-30
JP3279707B2 (ja)	2002-04-30
FI931329L (fi)	1993-09-27
US5468758A (en)	1995-11-21
NZ247234A (en)	1995-12-21
CZ44393A3 (en)	1994-01-19
SK280555B6 (sk)	2000-03-13
AU3541393A (en)	1993-09-30
SI9300150B (sl)	1998-06-30
NO300975B1 (no)	1997-08-25
CA2092510C (en)	2004-02-03
PL172890B1 (pl)	1997-12-31
NO931112L (no)	1993-09-27
CA2092510A1 (en)	1993-09-27
CZ286590B6 (cs)	2000-05-17
BR1100564A (pt)	2000-06-27
EP0567767A1 (de)	1993-11-03
ES2118846T3 (es)	1998-10-01
HU211131A9 (en)	1995-10-30
HRP930479A2 (en)	1995-02-28
PL298263A1 (en)	1994-01-10
DK0567767T3 (da)	1999-02-01
HUT63846A (en)	1993-10-28
HU211075B (en)	1995-10-30
DE69319955T2 (de)	1999-04-15
SG43225A1 (en)	1997-10-17
TW385310B (en)	2000-03-21
EP0567767B1 (de)	1998-07-29
FI931329A0 (fi)	1993-03-25
ATE169016T1 (de)	1998-08-15
HRP930479B1 (en)	1999-10-31
SI9300150A (en)	1993-09-30
IL105143A (en)	1996-10-16
DE69319955D1 (de)	1998-09-03
UY25939A1 (es)	2001-08-27
HK1010719A1 (en)	1999-06-25
AU654082B2 (en)	1994-10-20
HU9300868D0 (en)	1993-06-28
RU2125054C1 (ru)	1999-01-20
UY25938A1 (es)	2000-09-29

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