PH30490A - Hypoglycemic agents - Google Patents

Hypoglycemic agents

Info

Publication number: PH30490A
Authority: PH; Philippines
Prior art keywords: hypoglycemic agents; triarylethylenes; aroylbenzothiophenes; phenylindoles; dihydronaphthalenes
Prior art date: 1993-06-24

Application number

PH48503A

Other languages

English (en)

Inventor

George J Cullinan

Terence T Yen

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-24

Filing date

1994-06-22

Publication date

1997-05-28

1994-06-22 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1997-05-28 Publication of PH30490A publication Critical patent/PH30490A/en

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrane Compounds (AREA)
Indole Compounds (AREA)
Furan Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Thiazole And Isothizaole Compounds (AREA)

PH48503A 1993-06-24 1994-06-22 Hypoglycemic agents PH30490A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US8221893A	1993-06-24	1993-06-24

Publications (1)

Publication Number	Publication Date
PH30490A true PH30490A (en)	1997-05-28

Family

ID=22169806

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH48503A PH30490A (en)	1993-06-24	1994-06-22	Hypoglycemic agents

Country Status (23)

Country	Link
US (1)	US5567713A (de)
EP (1)	EP0635264B1 (de)
JP (1)	JP2886453B2 (de)
KR (1)	KR100325034B1 (de)
CN (1)	CN1086576C (de)
AT (1)	ATE157869T1 (de)
AU (1)	AU669627B2 (de)
CA (1)	CA2126400A1 (de)
CZ (1)	CZ285522B6 (de)
DE (1)	DE69405491T2 (de)
DK (1)	DK0635264T3 (de)
ES (1)	ES2105525T3 (de)
GR (1)	GR3025315T3 (de)
HU (1)	HUT75253A (de)
IL (1)	IL110052A (de)
NO (1)	NO312398B1 (de)
NZ (1)	NZ260790A (de)
PH (1)	PH30490A (de)
PL (1)	PL181025B1 (de)
RU (1)	RU2132682C1 (de)
TW (1)	TW275584B (de)
UA (1)	UA34441C2 (de)
ZA (1)	ZA944377B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6515009B1 (en)	1991-09-27	2003-02-04	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en)	1993-01-28	1998-09-22	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
USRE39049E1 (en)	1992-07-28	2006-03-28	Eli Lilly And Company	Methods for inhibiting bone loss
USRE38968E1 (en)	1992-07-28	2006-02-07	Eli Lilly And Company	Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride
TW366342B (en) *	1992-07-28	1999-08-11	Lilly Co Eli	The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
US6251920B1 (en)	1993-05-13	2001-06-26	Neorx Corporation	Prevention and treatment of cardiovascular pathologies
US6491938B2 (en)	1993-05-13	2002-12-10	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
WO1996040098A2 (en) *	1995-06-07	1996-12-19	Neorx Corporation	Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
US6417198B1 (en)	1993-12-21	2002-07-09	Eli Lilly And Company	Methods of inhibiting CNS problems in post-menopausal women
US5478847A (en)	1994-03-02	1995-12-26	Eli Lilly And Company	Methods of use for inhibiting bone loss and lowering serum cholesterol
US5629425A (en) *	1994-09-19	1997-05-13	Eli Lilly And Company	Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
CO4410191A1 (es)	1994-09-19	1997-01-09	Lilly Co Eli	SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS
US6562862B1 (en)	1994-10-20	2003-05-13	Eli Lilly And Company	Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
US6391892B1 (en) *	1995-03-10	2002-05-21	Eli Lilly And Company	Naphthyl pharmaceutical compounds
IL120266A (en)	1996-02-28	2005-05-17	Pfizer	Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
TW442286B (en) *	1996-02-28	2001-06-23	Pfizer	New therapeutic uses of estrogen agonists
AU5258696A (en) *	1996-03-19	1997-10-10	Eli Lilly And Company	Synthesis of 3-{4-(2-aminoethoxy)-benzoyl}-2-aryl-6-hydroxy-benzo{b}thiop henes
US6465445B1 (en)	1998-06-11	2002-10-15	Endorecherche, Inc.	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en)	1998-06-11	2006-02-28	Endorecherche, Inc.	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
JP4790178B2 (ja) *	1999-07-06	2011-10-12	アンドルシェルシュ・インコーポレイテッド	体重増加の処置方法および／または抑制方法
AU7896100A (en) *	1999-10-14	2001-04-23	Endorecherche Inc.	Selective estrogen receptor modulators in the treatment or reduction of the riskof acquiring hypertension, cardiovascular diseases, and insulin resistance
US6613083B2 (en)	2001-05-02	2003-09-02	Eckhard Alt	Stent device and method
US20030216358A1 (en) *	2001-07-05	2003-11-20	Muchmore Douglas Boyer	Method for enhancing bone mineral density gain
RU2198199C1 (ru) *	2001-09-21	2003-02-10	Закрытое акционерное общество научно-производственная компания "Панджшер-Холдинг"	Способ получения топливных дистиллятов
RU2188000C1 (ru) *	2001-09-27	2002-08-27	Нестерук Владимир Викторович	Лекарственное средство на основе тамоксифена
US20060106010A1 (en) *	2003-05-27	2006-05-18	Black Larry J	Methods for inhibiting bone loss
CA2697057A1 (en) *	2007-08-22	2009-02-26	Gilead Colorado, Inc.	Therapy for complications of diabetes
US20120172344A1 (en) *	2009-07-16	2012-07-05	Kyushu University, National University Corporation	Insulin-producing cell inducer, glucose intake enhancer, and therapeutic agent for diabetes or diabetes complications
EP3205648A1 (de)	2010-06-10	2017-08-16	Seragon Pharmaceuticals, Inc.	Östrogenrezeptormodulatoren und verwendungen davon
EP2791132A4 (de)	2011-12-14	2015-08-05	Seragon Pharmaceuticals Inc	Östrogenrezeptormodulatoren und verwendungen davon
EP3493794A4 (de) *	2016-08-04	2020-05-06	University of Iowa Research Foundation	Verwendung von swell1-inhibitoren und -modulatoren zur behandlung von typ-2-diabetes und adipositas

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2914563A (en) *	1957-08-06	1959-11-24	Wm S Merrell Co	Therapeutic composition
US3274213A (en) *	1961-09-05	1966-09-20	Upjohn Co	Alkoxy-substituted 2-phenyl-1-(tertiary-aminoalkoxy)phenyl-3, 4-dihydronaphthalenes
BE637389A (de) *	1962-09-13
US4133814A (en) *	1975-10-28	1979-01-09	Eli Lilly And Company	2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4230862A (en) *	1975-10-28	1980-10-28	Eli Lilly And Company	Antifertility compounds
US4323707A (en) *	1975-10-28	1982-04-06	Eli Lilly And Company	Antifertility compounds
US4400543A (en) *	1975-10-28	1983-08-23	Eli Lilly And Company	3-Phenyl-4-benzoyl-1,2-dihydronaphthalenes
US4418068A (en) *	1981-04-03	1983-11-29	Eli Lilly And Company	Antiestrogenic and antiandrugenic benzothiophenes
US4729999A (en) *	1984-10-12	1988-03-08	Bcm Technologies	Antiestrogen therapy for symptoms of estrogen deficiency
US4970237A (en) *	1987-03-20	1990-11-13	Yale University	Use of clomiphene to increase bone mass in premenopausal women
FR2654337B1 (fr) *	1989-11-15	1994-08-05	Roussel Uclaf	Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
DE69023906T2 (de) *	1990-08-09	1996-04-11	Council Scient Ind Res	Benzopyrane und Verfahren zu deren Herstellung.
JPH04312526A (ja) *	1991-04-09	1992-11-04	Fujisawa Pharmaceut Co Ltd	骨疾患治療剤
JP3157882B2 (ja) *	1991-11-15	2001-04-16	帝国臓器製薬株式会社	新規なベンゾチオフエン誘導体

1994
- 1994-06-20 AT AT94304441T patent/ATE157869T1/de not_active IP Right Cessation
- 1994-06-20 TW TW083105543A patent/TW275584B/zh active
- 1994-06-20 DE DE69405491T patent/DE69405491T2/de not_active Expired - Fee Related
- 1994-06-20 ZA ZA944377A patent/ZA944377B/xx unknown
- 1994-06-20 IL IL11005294A patent/IL110052A/en not_active IP Right Cessation
- 1994-06-20 ES ES94304441T patent/ES2105525T3/es not_active Expired - Lifetime
- 1994-06-20 EP EP94304441A patent/EP0635264B1/de not_active Expired - Lifetime
- 1994-06-20 DK DK94304441.2T patent/DK0635264T3/da active
- 1994-06-20 NZ NZ260790A patent/NZ260790A/en unknown
- 1994-06-20 CZ CZ941520A patent/CZ285522B6/cs not_active IP Right Cessation
- 1994-06-21 NO NO19942363A patent/NO312398B1/no not_active IP Right Cessation
- 1994-06-21 CA CA002126400A patent/CA2126400A1/en not_active Abandoned
- 1994-06-21 PL PL94303937A patent/PL181025B1/pl unknown
- 1994-06-22 AU AU64882/94A patent/AU669627B2/en not_active Ceased
- 1994-06-22 PH PH48503A patent/PH30490A/en unknown
- 1994-06-22 UA UA94005271A patent/UA34441C2/uk unknown
- 1994-06-22 KR KR1019940014148A patent/KR100325034B1/ko not_active Expired - Fee Related
- 1994-06-23 CN CN94107566A patent/CN1086576C/zh not_active Expired - Fee Related
- 1994-06-23 HU HU9401904A patent/HUT75253A/hu unknown
- 1994-06-23 RU RU94022479A patent/RU2132682C1/ru not_active IP Right Cessation
- 1994-06-23 JP JP6141553A patent/JP2886453B2/ja not_active Expired - Fee Related
1995
- 1995-01-09 US US08/370,062 patent/US5567713A/en not_active Expired - Fee Related
1997
- 1997-11-07 GR GR970402957T patent/GR3025315T3/el unknown

Also Published As

Publication number	Publication date
US5567713A (en)	1996-10-22
NZ260790A (en)	1997-06-24
PL303937A1 (en)	1995-01-09
ZA944377B (en)	1995-12-20
IL110052A0 (en)	1994-10-07
CN1100933A (zh)	1995-04-05
DE69405491D1 (de)	1997-10-16
KR100325034B1 (ko)	2002-08-21
UA34441C2 (uk)	2001-03-15
EP0635264A2 (de)	1995-01-25
ES2105525T3 (es)	1997-10-16
GR3025315T3 (en)	1998-02-27
HUT75253A (en)	1997-05-28
KR950000145A (ko)	1995-01-03
TW275584B (de)	1996-05-11
NO312398B1 (no)	2002-05-06
PL181025B1 (pl)	2001-05-31
ATE157869T1 (de)	1997-09-15
CZ285522B6 (cs)	1999-08-11
EP0635264A3 (de)	1995-04-12
NO942363L (no)	1994-12-27
AU6488294A (en)	1995-01-05
JP2886453B2 (ja)	1999-04-26
CN1086576C (zh)	2002-06-26
RU2132682C1 (ru)	1999-07-10
RU94022479A (ru)	1997-03-20
CZ152094A3 (en)	1995-03-15
IL110052A (en)	2001-04-30
HU9401904D0 (en)	1994-09-28
NO942363D0 (de)	1994-06-21
AU669627B2 (en)	1996-06-13
CA2126400A1 (en)	1994-12-25
DK0635264T3 (da)	1997-10-20
EP0635264B1 (de)	1997-09-10
DE69405491T2 (de)	1998-02-19
JPH0748252A (ja)	1995-02-21

Publication	Publication Date	Title
IL110052A0 (en)	1994-10-07	Hypoglycemic agents
HU9502193D0 (en)	1995-09-28	Combination treatment for inhibiting bone loss
PH30032A (en)	1996-11-08	Methods for inhibiting bone loss
EG24755A (en)	2010-07-26	Glucagon-like peptide -1 analogs.
GB2317615A (en)	1998-04-01	Antifungal agent compound therefor process for producing the same
NZ333588A (en)	2000-07-28	Sulphamates as anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS)
GB2359077B (en)	2004-04-14	Pushout mechanism for I.S. machine
GB2223404B (en)	1992-04-08	Inositoltrisphosphate for the treatment of abnormal levels of lipoproteins
HUT50787A (en)	1990-03-28	Process for producing pharmaceutical compositions comprising 4-aryl-4-piperidine-, pyrrolidine- or hexahydroazepincarbinol derivatives or heterocyclic analogs thereof as active ingredient and process for producing the new compounds
NZ247406A (en)	1999-05-28	Treatment of osteoporosis with 1 alpha, 24(r)-dihydroxy-22(e)-dehydro-vitamin d3
GR3018651T3 (en)	1996-04-30	Treatment of ocular hypertention with a synergistic combination
EP0641533A3 (de)	1996-04-10	Sitz eines Operateurstuhles.
UA29461C2 (uk)	2000-11-15	Засіб для лікування амілоїдозу, спосіб лікування амілоїдозу
EP0488587A3 (en)	1993-09-15	Plunger mechanism for an i.s. machine
EP0799181A4 (de)	1998-03-25	3,3-(disubstituierte)cyclohexan-1-carbonsäure dimere und derivate
FR2631966B1 (de)	1992-03-13
PL281255A1 (en)	1991-03-11	Method for manufacturing a new 3-(6,6-dimethylbicyclo (3.1.0) hextrans-3-yl) ethyl (prop-2)e) enate
PL281256A1 (en)	1991-03-11	Method for manufacturing a new 3-(6,6-dimethylbicyclo (3.1.0) hextrans-3-yl) ehtyl propanion
PL281257A1 (en)	1991-03-11	Method for manufacturing a new 3-(6,6-dimethylbicyclo (3.1.0) hextrans-3-yl propanol